Journal of Ultrasound in Medicine最新文献

{"title":"Low-Intensity Pulsed Ultrasound Delays the Onset of Osteoporosis and Dyslipidemia in Mice With Premature Ovarian Insufficiency","authors":"Juan Deng MMed,&nbsp;Junfen Li BS,&nbsp;Xinbin Han BE,&nbsp;Yiqing Zhou BS,&nbsp;Sicheng He BS,&nbsp;Jie Xu BS,&nbsp;Juan Qin PhD,&nbsp;Guolin Song MMed,&nbsp;Xinfang Xiao MMed,&nbsp;Liu Wu MMed,&nbsp;Yan Wang PhD","doi":"10.1002/jum.16641","DOIUrl":"10.1002/jum.16641","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The pathogenesis of premature ovarian insufficiency (POI) not only affects the ovarian structure and function but also gives rise to complications such as osteoporosis and dyslipidemia. Although low-intensity pulsed ultrasound (LIPUS) has been proven effective in treating POI, its impact on the associated complications remains unexplored. Therefore, this study aims to investigate the effects of LIPUS irradiation on osteoporosis and dyslipidemia in a mouse model of POI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The post-treatment complications following LIPUS cessation were monitored in POI rats at 30 and 120 days in this trial conducted by us. The secretion of follicle-stimulating hormone (FSH) was assessed using enzyme-linked immunosorbent assay (ELISA) at different time points in POI rats. Pathological changes in the liver and femur were observed through HE staining. Blood lipid and bone metabolism indexes were measured via blood biochemical testing. Osteoporosis was evaluated using MicroCT and Masson staining techniques. The expression level of inflammatory factors in bone tissue was detected by Western blot (WB) test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The serum FSH content showed a significant decrease in the LIPUS group on day 0, day 15, and day 30 (<i>P</i> &lt; .05). On the 30th day following LIPUS treatment, TC, TG, and LDL-C decreased in the LIPUS group while HDL-C increased with no statistically significant differences (<i>P</i> &gt; .05); the indexes of femur parameters (BS/TV, BV/TV, Tb.Th, BMD, and TMD) were increased (<i>P</i> &gt; .05). On the 120th day after LIPUS treatment, TC content demonstrated a significant decrease (<i>P</i> &lt; .05), and TG and LDL-C displayed a downward trend (<i>P</i> &gt; .05) while HDL-C content increased (<i>P</i> &lt; .05); the femur parameters were significantly reduced (<i>P</i> &lt; .05). The LIPUS group exhibited an increased presence of new fibrillar fibers. Levels of IL-6 and IL-1β significantly decreased with LIPUS treatment, whereas osteocalcin (OCN) expression notably increased (<i>P</i> &lt; .05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The application of LIPUS demonstrates potential in mitigating complications associated with POI in rats through the reduction of FSH secretion levels and inhibition of tissue inflammation, thereby presenting a promising avenue for women with POI to explore more efficacious treatment alternatives.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 5","pages":"819-829"},"PeriodicalIF":2.1,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142927362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of Acute Cholecystitis Based on Combination of Patient Age, Patient Sex, Leukocytosis, and Sonographic Murphy Sign","authors":"Anika G. Patel BA,&nbsp;Lea Chen BS,&nbsp;Scott W. Young MD,&nbsp;Nirvikar Dahiya MD, FACR,&nbsp;Nan Zhang MS,&nbsp;Maitray D. Patel MD, FACR","doi":"10.1002/jum.16640","DOIUrl":"10.1002/jum.16640","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To combine sonographic Murphy sign (SMS) with clinical parameters to effectively stratify patients into risk groups for acute cholecystitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Consecutive emergency department patients from April 1, 2019 to August 31, 2022 with possible acute cholecystitis were grouped using patient age, sex, and white blood cell count to determine the rate of acute cholecystitis found in subgroups. Three distinct clinical risk groups were established and then regrouped by prospective assessment of SMS into three non-imaging risk groups. Differences in the rate of acute cholecystitis for clinical parameters, clinical risk groups, and non-imaging risk groups were statistically analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 1231 patients (mean [SD] age, 51.2 [19.5]; 476 [38.7%] male), 156 had acute cholecystitis (mean [SD] age, 62.0 [15.4]; 85 [54.5%] male). Rates differed based on sex (9.4% female vs 17.9% male, <i>P</i> &lt; .001), age group (1.8% for patients &lt;30 years, 9.0% for patients 30–59 years, 22.3% for patients ≥60 years; <i>P</i> &lt; .001), and white blood cell count (23.1% elevated vs 6.6% not elevated; <i>P</i> &lt; .001). The low, average, and high non-imaging risk groups had acute cholecystitis rates of 1.8%, 14.0%, and 43.1%, respectively. Relative risk (95% CI) for the low non-imaging group compared with others was 0.07 (0.04, 0.12; <i>P</i> &lt; .001); relative risk for the high non-imaging risk group compared with others was 7.05 (5.32, 9.43; <i>P</i> &lt; .001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Sonographic Murphy sign assessment combined with patient age, sex, and white blood cell count effectively stratifies acute care patients into distinct acute cholecystitis risk groups.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 5","pages":"807-816"},"PeriodicalIF":2.1,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142921939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved Birthweight Prediction With Feature-Wise Linear Modulation, GRU, and Attention Mechanism in Ultrasound Data","authors":"G. Mohana Priya ME,&nbsp;S. K. B. Sangeetha PhD","doi":"10.1002/jum.16633","DOIUrl":"10.1002/jum.16633","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Birthweight prediction in fetal development presents a challenge in direct measurement and often depends on empirical formulas based on the clinician's experience. Existing methods suffer from low accuracy and high execution times, limiting their clinical effectiveness. This study aims to introduce a novel approach integrating feature-wise linear modulation (FiLM), gated recurrent unit (GRU), and Attention network to improve birthweight prediction using ultrasound data.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The proposed method utilizes FiLM for adaptive modulation, dynamically adjusting layer activations based on input specifics for enhanced information extraction. GRU is employed to capture sequential dependencies, recognizing the evolving maternal and fetal parameters during pregnancy. The Attention network selectively focuses on crucial parameters, dynamically adjusting feature weights for accurate predictions. The study evaluates classification accuracies for three groups: appropriate-for-gestational-age, large-for-gestational-age, and small-for-gestational-age (SGA). Prediction errors are minimized by optimizing parameters and using mean squared error as the loss function. Experimental evaluations are performed using multiple metrics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The proposed strategy attains a high prediction accuracy of 98.8%, outperforming existing methods such as ensemble transfer learning model (83.5%), BabyNet++ (91.7%), bi-directional LSTM with CNN and a hybrid whale with oppositional fruit fly optimization (89.2%), linear regression–random forest–artificial neural network (79.5%), and Attention MFP-Unet (93.6%). The integrated network provides advanced insights into birthweight dynamics, enhancing both interpretability and accuracy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The findings of this study are vital for birthweight prediction, clinical delivery guideline development, and implementation of decision-making. The proposed approach supports clinicians in making informed decisions during obstetric examinations and assists pregnant women in weight management, showcasing significant advancements in maternal healthcare.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 4","pages":"711-725"},"PeriodicalIF":2.1,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on Ultrasound Diagnostic Criteria and New Ultrasound Severity and Activity Scorings of Hidradenitis Suppurativa: Modified SOS-HS and US-HAS","authors":"Corrado Tagliati MD","doi":"10.1002/jum.16637","DOIUrl":"10.1002/jum.16637","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 4","pages":"789"},"PeriodicalIF":2.1,"publicationDate":"2024-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Hidradenitis Suppurativa Assessment","authors":"Alessandra Michelucci MD,&nbsp;Giammarco Granieri MD,&nbsp;Bianca Cei MD,&nbsp;Flavia Manzo Margiotta MD,&nbsp;Agata Janowska MD,&nbsp;Teresa Oranges MD, PhD,&nbsp;Marco Romanelli MD, PhD,&nbsp;Valentina Dini MD, PhD","doi":"10.1002/jum.16635","DOIUrl":"10.1002/jum.16635","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease affecting hair follicles, causing recurrent abscesses and nodules in intertriginous regions. The International HS Severity Score System (IHS4) is widely used to assess HS severity by counting inflammatory nodules, abscesses, and draining fistulas/tunnels. However, traditional clinical examinations may underestimate HS severity due to the presence of subclinical lesions. This study aims to enhance the accuracy of HS severity assessment by incorporating ultra-high frequency ultrasound (UHFUS) to detect subclinical lesions, such as microtunnels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A cohort of 122 patients with HS (75 females and 47 males) was evaluated. Clinical severity was assessed using the IHS4 scoring system. UHFUS assessments were performed using a 70 MHz probe for patients with mild and moderate IHS4 scores. Statistical tools were used to assess the significance of UHFUS in detecting additional lesions not identified during clinical examinations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study found that 23% of patients had mild HS, 58.2% had moderate HS, and 18.9% had severe HS according to IHS4. Among the 28 patients with mild IHS4, 14 had microtunnels detected by UHFUS, leading to a change in disease staging: 11.5% of patients were reclassified as mild, while 69.7% were reclassified as moderate. A statistically significant difference in the distribution of severity classifications before and after UHFUS examination was observed (<i>χ</i>² = 5.11, <i>P</i> = .0238).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The study underscores the critical role of UHFUS as a non-invasive technique for the precise assessment of HS. The integration of UHFUS with a 70 MHz probe significantly enhances the detection of subclinical lesions, such as microtunnels, enabling timely intervention and potentially preventing disease progression. Despite the study's limitations, including its monocentric design and small sample size, the findings support the use of UHFUS in improving the accuracy of HS severity assessment.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 4","pages":"739-745"},"PeriodicalIF":2.1,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142871245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Median Nerve Displays Adaptive Characteristics When Exposed to Repeated Pinch Grip Efforts of Varying Rates of Force Development","authors":"Denise Balogh MSc,&nbsp;Aaron M. Kociolek PhD","doi":"10.1002/jum.16634","DOIUrl":"10.1002/jum.16634","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Repeated gripping with high grip forces and high rates of grip force development are risk factors for carpal tunnel syndrome. As the nerve's adaptive ability is crucial to prevent disease progression, we investigated how these risk factors influence median nerve deformation and displacement over the time course of a repeated pinch grip task.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Seventeen healthy participants performed a repeated grip task against a load cell while their carpal tunnel was scanned with ultrasound. The grip task involved pulp-pinching three consecutive times from 0 to 40% maximal voluntary exertion (MVE), performed at three different rates of force development (RFD): 40% MVE/1 second; 2 seconds; and 5 seconds. Ultrasound images were analyzed at 10% MVE intervals. Nerve circularity, width, height, and cross-sectional area were measured to assess deformation. Median nerve displacement was assessed by its change in position relative to the flexor digitorum superficialis tendon of the third digit (FD) in both radioulnar and palmodorsal axes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Linear mixed modeling indicated that median nerve deformation increased, becoming more circular, with each repeated pulp-pinch (<i>P</i> &lt; .01) and with grip force magnitude (<i>P</i> &lt; .01). However, a faster RFD decreased nerve deformation (<i>P</i> &lt; .01). Furthermore, the nerve displaced ulnarly during pulp-pinching, with greater displacement during the fastest (ie, 40% MVE/1 second) RFD (<i>P</i> &lt; .01).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The median nerve deformed and displaced in response to pulp-pinching; however, faster rates of force development hindered this adaptive response. This likely reflects the viscoelastic properties of the healthy nerve and subsynovial connective tissue, highlighting the importance of tissue compliance in preventing nerve compression.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 4","pages":"727-738"},"PeriodicalIF":2.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jum.16634","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Pattern of Congenital Smooth Muscle Hamartoma of the Skin","authors":"Victor Meza MD,&nbsp;Ligia Aranibar MD,&nbsp;Ximena Wortsman MD","doi":"10.1002/jum.16636","DOIUrl":"10.1002/jum.16636","url":null,"abstract":"<p>Smooth muscle hamartoma (SMH) of the skin is a cutaneous benign proliferation of mature smooth muscle. Congenital SMH (CSMH) of the skin represents the most frequent type, and to date, there are no reports on its ultrasonographic pattern. A retrospective study of the color Doppler ultrasound (US) images of six CSMH patients at high and ultra-high frequencies was performed. Demographic data and US characteristics were analyzed. All cases presented a focal area of dermal thickening, decreased dermal echogenicity, and/or distorted dermal regions with prominent hair follicles. A total of 83.3% of cases showed no signs of internal vascularity at color Doppler imaging. Ultrasonographic features can support clinical diagnosis and follow-up of CSMH, which may potentially avoid biopsies.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 4","pages":"779-785"},"PeriodicalIF":2.1,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonographic Features of the Fallopian Tubes","authors":"Irene Colombi MD,&nbsp;Federica Perelli MD,&nbsp;Silvia Pisaneschi MD,&nbsp;Marco Riccio MD,&nbsp;Alessandro Ginetti MD,&nbsp;Alberto Cannoni MD,&nbsp;Errico Zupi MD,&nbsp;Alberto Mattei MD,&nbsp;Lucia Lazzeri MD","doi":"10.1002/jum.16628","DOIUrl":"10.1002/jum.16628","url":null,"abstract":"<p>Fallopian tubes are not usually visible on a transvaginal pelvic scan unless pelvic fluid or pathological processes are present. Depending on the underlying pathological process, they may exhibit different wall thicknesses, grades of vascularization, and variable echogenicity. Recognizing the affected tube and assessing the possible underlying process is of primary importance in clinical practice, as pathological tubes may represent benign pathologies, oncological state, or life-threatening conditions requiring different treatment to preserve fertility. The aim of this pictorial review is to describe the main characteristics of the most common tubal pathologies to help clinicians recognize them.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 4","pages":"759-777"},"PeriodicalIF":2.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sonographic Characterization of Red-Blue Neurofibromas in Patients With Neurofibromatosis Type 1","authors":"Inés Oteiza-Rius MD,&nbsp;Ángela Estenaga Pérez de Albéniz MD,&nbsp;Ángela Hernández-Martin MD, PhD,&nbsp;Fernando Alfageme Roldán MD, PhD,&nbsp;Francisco Javier García-Martínez MD, PhD","doi":"10.1002/jum.16632","DOIUrl":"10.1002/jum.16632","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Red-blue neurofibromas (RBNs), found in up to 29% of adult neurofibromatosis type 1 (NF1) patients, present as red-blue macules measuring 1–2 cm in diameter, primarily on the trunk. Despite their prevalence, RBNs often go unnoticed due to their subtle appearance. Ultrasound characterization serves as a diagnostic clue yet lacks comprehensive studies in both adult and pediatric populations. This study aims to define and compare RBNs' prevalence, characteristics, and ultrasound features in adult and pediatric patients with NF1.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This prospective study involved 118 patients (92 pediatric patients and 26 adults) diagnosed with NF1. Clinical examinations combined with cutaneous ultrasound scans using linear multifrequency probes (L4–12t, L10–22, ML6–15, or L8–18 MHz) were performed in order to determine the prevalence, and clinical and sonographic characteristics of RBN in both populations. Statistical analyses were performed using <i>t</i> tests and chi-square tests.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>RBNs were found in 26.3% (31) of the patients after clinical examination, including 179 lesions. RBN prevalence differed significantly between pediatric (10.9%) and adult (66.7%) patients. Lesions were primarily on the trunk and exhibited similar clinical characteristics. Ultrasound reveals RBNs as hypoechoic, oval lesions with irregular borders. Our results show that pediatric RBNs are typically more superficial and hypoechogenic, while adult RBNs are deeper and more heterogeneous.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Ultrasound findings showed subtle differences in lesion depth, morphology, and echogenicity between these 2 age-related groups. These changes highlight ultrasound's role in identifying RBNs in patients with NF1 and monitoring their evolution.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 4","pages":"703-709"},"PeriodicalIF":2.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jum.16632","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Multimodal Imaging Features of Hepatic Inflammatory Pseudotumors","authors":"Keke Chen MD,&nbsp;Minhua Luo MD,&nbsp;Yuhong He MD,&nbsp;Danqing Huang MD,&nbsp;Min Tang MD,&nbsp;Jiong Shi MD,&nbsp;Hong Qin MD,&nbsp;Minying Deng MD,&nbsp;Wenping Wang PhD,&nbsp;Wentao Kong PhD","doi":"10.1002/jum.16629","DOIUrl":"10.1002/jum.16629","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Current literature on imaging characteristics of hepatic inflammatory pseudotumor (HIPT) is limited. This study aimed to analyze the contrast-enhanced ultrasound (CEUS) features in HIPT and compare them with contrast-enhanced computed tomography (CECT) and contrast-enhanced magnetic resonance imaging (CEMRI).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 83 patients with histologically proven HIPT from two medical institutions were included in this study. All patients underwent CEUS within 1 week before surgery or biopsy. Some patients received additional CECT or CEMRI. B-mode ultrasound (BMUS) features, enhancement parameters of CEUS, CECT and CEMRI were analyzed. Chi-square test was used to compare the enhancement patterns and diagnostic sensitivity between CEUS and CECT/CEMRI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>On the BMUS, HIPT mainly appeared hypoechoic (83.5%, 66/79), irregular shapes (62.0%, 49/79), heterogeneous echogenicity (72.2%, 57/79), and unclear boundary (65.8%, 52/79). A total of 61.5% (51/83) lesions exhibited mild hyper- or iso-enhancement in the arterial phase (AP), 59.0% (49/83) lesions had internal nonenhanced areas, and most lesions (71.1%, 59/83) showed early wash-out (&lt;60 seconds) on the CEUS. There were significant differences between CEUS and CECT/CEMRI in enhancement intensity of AP and wash-out pattern (<i>P</i> &lt; .05). The sensitivity in the diagnosis of HIPT among the three had no statistical difference (<i>P</i>&gt;.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The CEUS features of HIPT lesions typically include mildly hyper-enhanced or iso-enhanced in AP, rapid wash-out in PVP, and often small nonenhanced areas within the mass. Furthermore, the wash-out pattern of CEUS and CECT/CEMRI are inconsistent, more akin to cholangiocarcinoma. The diagnostic efficacy of the three modalities is similar.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 4","pages":"691-701"},"PeriodicalIF":2.1,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}