Journal of Ultrasound in Medicine最新文献

{"title":"Proof of Concept: Super-Resolution Ultrasound and Viscoelastic Imaging of Hepatic Microcirculation for Early Detection and Staging of Liver Fibrosis in a Murine Model","authors":"Rui Zhang MD,&nbsp;Jieqiong Wang MD,&nbsp;Tingting Liu MMed,&nbsp;Yan Wang MD,&nbsp;Shuai Yang MMed,&nbsp;Fei Yan PhD,&nbsp;Li Xue MD","doi":"10.1002/jum.16703","DOIUrl":"10.1002/jum.16703","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Super-resolution ultrasound microvascular imaging (SRUS) has emerged as a noninvasive technology capable of visualizing the microvasculature with exceptional spatial resolution, surpassing the acoustic diffraction limit. This study aims to assess the potential of SRUS in staging liver fibrosis by evaluating its diagnostic performance against ultrasound viscosity imaging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Liver fibrosis was induced by carbon tetrachloride (CCl₄) in 30 mice. The mice were evenly distributed across five stages (6 mice per stage), categorized from F0 (no fibrosis) to F4 (cirrhosis) based on the extent of collagen deposition. SRUS microvascular imaging and ultrasound viscosity imaging were compared for their efficacy in detecting liver fibrosis stages. Immunohistochemistry and histopathological analyses were conducted to correlate vessel density and collagen deposition.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>SRUS effectively detected microvascular changes across all fibrosis stages. Significant vessel diameter enlargement was observed at early stages (F1), with further increases in advanced stages (F3–F4). Vessel density significantly decreased in later stages, indicating compromised angiogenesis. Ultrasound viscosity imaging showed marked viscoelastic reductions in fibrosis but lacked sensitivity in early-stage detection. SRUS parameters exhibited strong correlations with histological findings, underscoring their potential diagnostic value. Receiver operating characteristic (ROC) curve analysis further demonstrated the superior sensitivity of SRUS (89.59% [95% confidence interval (CI): 84.87–92.96%]), particularly in distinguishing early-stage fibrosis (F0–F1) from advanced stages (F2–F4) (area under the curve [AUC] = 0.9610, 95% CI: 0.9449–0.9771; <i>P</i> &lt; .001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>SRUS microvascular imaging is a promising adjunct to traditional elastography, offering enhanced sensitivity for early-stage liver fibrosis detection. It provides critical insights into microcirculatory dysfunction, complementing stiffness measurements and aiding in accurate diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1481-1491"},"PeriodicalIF":2.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Machine Learning Model for Predicting Axillary Lymph Node Metastasis in Clinically Node Positive Breast Cancer Based on Peritumoral Ultrasound Radiomics and SHAP Feature Analysis”","authors":"","doi":"10.1002/jum.16692","DOIUrl":"10.1002/jum.16692","url":null,"abstract":"<p>Wang SR, Cao CL, Du TT, et al. Machine learning model for predicting axillary lymph node metastasis in clinically node positive breast cancer based on peritumoral ultrasound radiomics and SHAP feature analysis. <i>J Ultrasound Med</i>. 2024;43(9):1611–1625. doi:10.1002/jum.16483</p><p>The author attributions should have been written as: “Si-Rui Wang^†, BMed, Chun-Li Cao^†, MM, Ting-Ting Du, MM, Jin-Li Wang, BMed, Jun Li, PhD, Wen-Xiao Li, MM, Ming Chen, MM. ^†These authors have contributed equally to this work.”</p><p>We apologize for this error.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 7","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jum.16692","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Fetal Posterior Fossa Anomalies at 11–13+6 Gestational Weeks in the Midsagittal Cranial Plane by Three-Dimensional Multiplanar Sonography","authors":"Feng-Qin Liu MD,&nbsp;Ze-Xuan Yang MD,&nbsp;Lin-Hua Yang MD,&nbsp;Ji-Mei Xi MD,&nbsp;Lin Chen MD,&nbsp;Liu-Ying Zhou MD,&nbsp;De-Xin Chen MD","doi":"10.1002/jum.16691","DOIUrl":"10.1002/jum.16691","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The aim of this study was to describe the sonographic appearance of posterior fossa anomalies in fetuses at 11–13⁺⁶ weeks' gestation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This prospective study included 60 healthy fetuses and 15 fetuses with an abnormal posterior brain at 11–13⁺⁶ weeks' gestation. All three-dimensional images were processed using multiplanar image correlation to view the posterior fontanelle in the midsagittal views. The final diagnosis of all fetuses was confirmed using second-trimester ultrasonography, fetal magnetic resonance imaging, and/or genetic testing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The brainstem morphology, fourth ventricle, choroid plexus of the fourth ventricle, vermis, and physiologic Blake pouch were clearly visualized at 11–13⁺⁶ weeks' gestation through the posterior fontanelle from the midsagittal view. Among the 15 fetuses analyzed, two had abnormal brainstem morphology, which was subsequently diagnosed as Walker–Warburg syndrome. The remaining 13 fetuses were diagnosed with posterior fossa cystic malformations (Dandy–Walker malformation, 2 fetuses; Blake's pouch cyst, 2 fetuses; Noonan syndrome, 1 fetus; trisomy 21, 2 fetuses; trisomy 18, 1 fetus; and transient dilatation of the fourth ventricle, 5 fetuses). The extended anterior membranous area and dysplastic vermis were strong markers of Dandy–Walker malformation. In fetuses with Blake pouch cysts, the vermis was visible, with the choroid plexus of the fourth ventricle located backward.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Sonography enables clear visualization of morphological changes in posterior fossa anomalies at 11–13⁺⁶ gestational weeks. An extended anterior membranous area, dysplastic vermis, and abnormal brainstem morphology are direct signs of early recognition of severe posterior fossa anomalies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1379-1387"},"PeriodicalIF":2.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"International Multicentric Study on Ultrasound Characteristics, Layer Location, and Corporal Distribution of Granulomas After Cosmetic Fillers Injections","authors":"Ximena Wortsman MD,&nbsp;Yessenia Valderrama MD,&nbsp;Gabriela Ortiz-Orellana MD,&nbsp;Claudia Gonzalez MD,&nbsp;Francisco de Cabo MD,&nbsp;Stella Desyatnikova MD,&nbsp;Fernanda Aquino Cavallieri MD,&nbsp;Patricia Barrera MD,&nbsp;Rosa Sigrist MD","doi":"10.1002/jum.16700","DOIUrl":"10.1002/jum.16700","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To provide insight into the characteristics, layer locations, and corporal distribution of the granulomatous reactions to cosmetic fillers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An international retrospective multicentric study was performed in centers that scan complications of cosmetic fillers. Inclusion criteria were patients with previous injections of known cosmetic fillers confirmed by ultrasound and ultrasonographic features of granulomatous reactions such as hypoechoic nodules, pseudonodules, or hypoechoic tissue surrounding the deposit regions. The ultrasound studies followed the published guidelines for performing dermatologic ultrasound examinations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 240 cases met the criteria. The leading fillers previously injected were 50.4% hyaluronic acid, 18.8% poly-L-lactic acid, 8.3% polymethylmethacrylate, 6.3% calcium hydroxyapatite, and 3.8% silicone oil. The main regions of granulomas were the lower lid, infraorbital, and medial cheek in 41.7%, the perioral region and lips in 19.2%, the lateral jaw and cheek in 14.6%, and the chin, pre-jowl, and medial jaw in 12.5%. The layers involved by the granulomatous reaction were hypodermis in 37.1%, the deep fat pad in 8.9%, the periosteum in 5.8%, the combination of hypodermis, deep fat pad, and muscle in 5.8%, and the combination of hypodermis, fascia, subfascial, deep fat pad, and muscle in 5.4%. The predominant corporal locations were the face, submandibular, and anterior neck, with 95.8% being 87.5% in the face.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Ultrasound can provide valuable and detailed anatomical information supporting diagnosis and management as well as valuable insights into the granulomatous reactions to fillers.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1447-1455"},"PeriodicalIF":2.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an Ultrasound-Based Clinical-Radiomic Nomogram for Predicting Histologic Subtypes in Focal Testicular Tumors","authors":"Tuo Lin MD,&nbsp;Shunping Chen MD,&nbsp;Shouliang Miao MD","doi":"10.1002/jum.16701","DOIUrl":"10.1002/jum.16701","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Testicular tumors are the most common solid malignancy among males aged 15–35. This study aimed to establish an ultrasound (US) based clinical-radiomic nomogram for the preoperative prediction of testicular tumors histologic subtypes, differentiating testicular germ cell tumors (TGCTs) from testicular non-germ cell tumors (TNGCTs) and then differentiating seminomas (SGCTs) from non-seminomatous tumors (NSGCTs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective study included 148 patients with testicular tumors confirmed by pathology, with 120 cases of TGCTs, including 65 SGCTs and 55 NSGCTs. All patients underwent preoperative ultrasound examinations, and data on clinical information, US features, and radiomics features were collected. The Radscore model was constructed after feature selection. Independent risk factors were identified using univariate and multivariate logistic regression analysis. The nomogram model was assessed using the receiver operating characteristic (ROC) curve analysis and decision curve analysis (DCA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The TGCTs radiomics nomogram model achieved AUCs of 0.89 in both the training and validation datasets. The SGCTs radiomics nomogram model achieved AUCs of 0.93 in the training dataset and 0.91 in the validation dataset, surpassing the predictive performance of both Radscore and clinical models. The calibration curves showed that the nomogram estimation was consistent with the actual observations. DCA also verified the clinical value of the combined model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The ultrasound-based clinical-radiomics nomogram has the potential to non-invasively discriminate the histologic subtypes of testicular tumors.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1457-1471"},"PeriodicalIF":2.1,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Value of Renal Resistive Index in Occult Hemorrhage in Hemodynamically Stable Polytrauma Patients in Emergency Department","authors":"Mustafa Arslan MD,&nbsp;Bedriye Müge Sönmez MD,&nbsp;Gülşen Akçay MD","doi":"10.1002/jum.16696","DOIUrl":"10.1002/jum.16696","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To find out if renal resistive index (RRI) is altered early in the course of posttraumatic hemorrhage and if it may be a surrogate marker of silent hypoperfusion and, in turn, hemorrhagic shock in polytrauma patients presenting to the emergency department (ED).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective single-center cross-sectional study was conducted on 195 patients presenting to the ED with hemodynamically stable polytrauma. The patients were evaluated according to the extended-focused assessments with sonography for trauma (e-FAST) protocol and then underwent RRI measurement using Doppler ultrasonography (US). Measurements were performed by an ED physician with a minimum of 4 years' experience in ED practice and USG examination, plus a certification to perform basic and advanced US training. The primary outcome was the development of hemorrhagic shock according to the American College of Surgeons Advanced Trauma Life Support (ATLS) hemorrhagic shock classification. The secondary outcome was the diagnostic performance of RRI in determining occult hemorrhage.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 84 patients (43.1%) developed hemorrhagic shock. There was a significant difference between the RRI levels of the groups with and without hemorrhagic shock (<i>P</i> &lt; .05). While most of the patients with a mean RRI of &lt;0.05 did not develop hemorrhagic shock, to the contrary, patients with a mean RRI of &gt;0.07 mainly developed hemorrhagic shock. When we used the RRI value as a diagnostic test to detect patients who developed hemorrhagic shock, the area under the curve value was 0.832 (<i>P</i> &lt; .001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>RRI can be a promising noninvasive, early marker of silent hemorrhage.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1405-1414"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Solid Hydrogel Sleeve Couplant for Ultrasound Imaging","authors":"Yunlong Bao PhD,&nbsp;Jiabin Zhang PhD,&nbsp;Jinyu Yang PhD,&nbsp;Yu Xia PhD,&nbsp;Dongdong Liang PhD,&nbsp;Yunlong Zhao PhD,&nbsp;Hao Yu PhD,&nbsp;Shuo Huang PhD,&nbsp;Wenyu Guo PhD,&nbsp;Jue Zhang PhD","doi":"10.1002/jum.16690","DOIUrl":"10.1002/jum.16690","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To address the challenges of ultrasound scanning on curvilinear skin surfaces at joints, this study introduces a novel Shapable and Elastic Couplants sleeve of Hydrogel (SECH) based on a “Curve-to-Smooth” strategy. The aim is to improve acoustic wave transmission, enhance image quality, and enable efficient 3D imaging of high-curvature body parts such as the hand, foot, shoulder, and neck.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The SECH was fabricated using acrylamide (AAm) as the primary monomer, N,N-methylenebisacrylamide (MBAA) as the crosslinking agent, ammonium persulfate (APS) as the initiator, and N,N,N′,N′-tetramethylethylenediamine (TEMED) as the accelerator. A dual-mold strategy was employed to shape the hydrogel to specific body parts. Mechanical characterization was performed using tensile tests and manual stretching/compression cycles. Ultrasound imaging was conducted on a healthy adult male volunteer using the Vevo F2 system with an L38 linear probe transducer. Cyclic scans were performed on the hand, foot, shoulder, and neck, and 3D image reconstruction was achieved using Matlab and ImageJ.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The SECH demonstrated effective mechanical properties, balancing softness and hardness to minimize air gaps and ensure stable acoustic wave transmission. Ultrasound imaging with SECH enabled high-quality 3D reconstructions of high-curvature body parts, including the hand, foot, shoulder, and neck. Multi-planar analysis of the images provided detailed diagnostic information for conditions such as hand fractures, Achilles tendon injuries, shoulder dislocations, and carotid artery stenosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The SECH represents a novel ultrasound scanning strategy that overcomes the limitations of conventional rigid probes on curvilinear surfaces. It facilitates large-area 3D imaging of high-curvature body parts, improving diagnostic accuracy and efficiency in clinical ultrasonography. This customizable hydrogel sleeve has the potential to enable convenient and automated ultrasound scanning for irregular anatomical areas.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1367-1377"},"PeriodicalIF":2.1,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transthoracic Ultrasound to Predict Exudative Pleural Effusion Etiology","authors":"Wanling Huang MD,&nbsp;Chaofan Yuan MD,&nbsp;Kinner M. Patel MD,&nbsp;Alice Mei DO,&nbsp;Kian Avilla BS,&nbsp;Xiaoyue Zhang MS,&nbsp;Sahar Ahmad MD","doi":"10.1002/jum.16687","DOIUrl":"10.1002/jum.16687","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objectives&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Pleural effusions often require invasive sampling to establish underlying etiologies. Transthoracic ultrasound (TUS) has shown promise in the diagnostics of pleural effusions; however, there lacks consensus regarding its clinical application. We evaluated the diagnostic utility of specific TUS findings for exudative effusions, specifically complex parapneumonic effusion and empyema.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Ultrasound-guided pleural effusion drainage cases were retrospectively reviewed at a single university-based medical center from July 2015 to May 2023. Procedure-related images were reviewed for specific ultrasound findings: anechoic, fibrin, septation, loculation, plankton/swirl sign, hematocrit sign, jellyfish sign, and visceral pleura thickening. Exudative or transudative nature, underlying etiology, and other patient data were collected from chart review. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and positive likelihood ratio (LR+) were calculated for these findings, either individually or in combination, to predict nature and specific etiology for pleural effusion. A multivariable logistic regression model was constructed to analyze the association between TUS findings and complicated parapneumonic effusion and empyema.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A total of 389 cases included, 252 (64.8%) were exudative and 137 (35.2%) were transudative effusions. Findings of anechoic and jellyfish sign were more common in the transudative group, while septation, loculation, and pleural thickening appeared more commonly in exudative effusion (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). Absence of all three signs of fibrin, septation, and loculation had 83% sensitivity (95% CI 77–90) and 78% NPV (95% CI 70–86) for transudative effusion. Septation and loculation had 98% specificity (95% CI 95–100) and 94% PPV (95% CI 88–100) for exudative effusion. Fibrin, loculation, and septation, when found concurrently, had 99% specificity (95% CI 98–100) and 96% PPV (95% CI 88–100) for exudative effusion. Multivariable logistic regression showed the presence of septation (odds ratio [OR] 5.3, 95% CI 1.7–16.3, &lt;i&gt;P&lt;/i&gt; = 0.0038) and loculation (OR 3.3, 95% CI 1.1–10.0, &lt;i&gt;P&lt;/i&gt; = 0.0327) were each independently associated with the likelihood of complicated parapneumonic and empyema cases.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;TUS features of loculation or septation are specific and predictive for exudative pleural effusion. The presence of septation and loculation was each associated with a higher likelihood of complicated parapneumonic effusion o","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1343-1353"},"PeriodicalIF":2.1,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143743315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Imaging and Guidance for Plantar Fascia Lesions","authors":"Pelin Analay MD,&nbsp;Murat Kara MD,&nbsp;Ahmad J. Abdulsalam MD,&nbsp;Berkay Yalçınkaya MD,&nbsp;Vincenzo Ricci MD,&nbsp;Giulio Cocco MD, PhD,&nbsp;Ondřej Naňka MD, PhD,&nbsp;Levent Özçakar MD","doi":"10.1002/jum.16694","DOIUrl":"10.1002/jum.16694","url":null,"abstract":"<p>Plantar fascia (PF) lesions, such as plantar fasciitis, PF tear, and plantar fibromatosis (Ledderhose disease), are among the common causes of heel pain. The management of these lesions includes conservative treatments, minimally invasive treatments, and surgical interventions. When conservative treatments fail, minimally invasive injection therapies have been proposed as alternatives for managing PF lesions. Despite the availability of various injectable options, where and how to perform the injection is still controversial in the pertinent literature. In this article, considering the paramount role of ultrasound imaging in the diagnosis, interventions, and follow-up for PF pathologies, we demonstrated our sonographic approach to PF lesions for sonographers/physicians in daily clinical practice.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1509-1518"},"PeriodicalIF":2.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Modifications in Management of Local Anesthetic Systemic Toxicity","authors":"Fu-Liang Yang BSc,&nbsp;Yan-Wen Li BSc,&nbsp;Yuan-Fu Zhou BSc,&nbsp;Liang He MD","doi":"10.1002/jum.16695","DOIUrl":"10.1002/jum.16695","url":null,"abstract":"","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":"44 8","pages":"1523-1524"},"PeriodicalIF":2.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}