{"title":"PP3.4 – 00100 Retinoids enhance NK effector functions against HIV infected CD4 T cells","authors":"E. Mcmahon, R. Lynch, A. Bosque","doi":"10.1016/j.jve.2024.100485","DOIUrl":"10.1016/j.jve.2024.100485","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 62"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143134584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Morán, Z. Gentry, O. Mcateer, J. Hamad, J.T. Kim, P. Wender, J. Zack, M. Marsden
{"title":"PP3.5 – 00089 Investigating novel designed and synthesized PKC modulators for use in “kick and kill” HIV cure strategies","authors":"J. Morán, Z. Gentry, O. Mcateer, J. Hamad, J.T. Kim, P. Wender, J. Zack, M. Marsden","doi":"10.1016/j.jve.2024.100486","DOIUrl":"10.1016/j.jve.2024.100486","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 62-63"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143135196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Espinosa Ortiz, R. Fromentin, S.G. Deeks, J.P. Routy, N. Chomont
{"title":"1.3 – 00084 Persistence of HIV genomes in bacteria-specific CD4+ T cells during ART","authors":"A. Espinosa Ortiz, R. Fromentin, S.G. Deeks, J.P. Routy, N. Chomont","doi":"10.1016/j.jve.2024.100396","DOIUrl":"10.1016/j.jve.2024.100396","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 2"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143176159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maximillian Kolbe Domapielle , Sadat Zakari Abugbila , Marshall Kala
{"title":"Bypassing primary antiretroviral therapy centres in Sub-Saharan Africa: An integrative review of the theoretical and empirical literature","authors":"Maximillian Kolbe Domapielle , Sadat Zakari Abugbila , Marshall Kala","doi":"10.1016/j.jve.2024.100580","DOIUrl":"10.1016/j.jve.2024.100580","url":null,"abstract":"<div><div>The uptake of antiretroviral therapy (ART) is critical to meeting the global HIV treatment goal of 95-95-95 by 2025. Although a few Sub-Saharan African countries have already achieved this target, the prevalence of bypassing primary ART centres in many countries in the subregion has negative implications for ART uptake and use. This study used the access to health services framework to analyse the evidence and factors contributing to bypassing primary ART centres by individuals in the sub-region seeking HIV care and support. We found compelling evidence of the prevalence of ART clients bypassing their primary ART centres in search of specialised care in higher-tiered health facilities. Others use bypassing to conceal their HIV-positive status to avoid social stigma. We argue that introducing specialised and differentiated ART at the primary level of care can address this phenomenon. While we anticipate that this measure will satisfy clients' desire for specialised care, we recommend enhancing public awareness about the effectiveness of ART to reduce stigma towards ART clients. Legislation and strict enforcement of anti-HIV stigma laws, which outlaw and criminalise stigmatising people living with HIV (PLHIV), could potentially be an effective stigma-deterring measure. To complement this effort, PLHIV should be empowered to understand legislative instruments and steps to take when confidentiality and discriminatory issues arise. We recommend further research in Sub-Saharan Africa to investigate the relationship between bypassing primary ART centres and client adherence. The findings will help design appropriate strategies to increase ART uptake at primary ART centres.</div></div>","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 4","pages":"Article 100580"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11751520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Perez-Blazquez, E. Valencia, L. Martin-Carbonero, E. Mateos, M. Coiras
{"title":"8.6 – 00097 Increased HIV-1 proviral reactivation and reservoir size in people with HIV on anticancer treatment","authors":"L. Perez-Blazquez, E. Valencia, L. Martin-Carbonero, E. Mateos, M. Coiras","doi":"10.1016/j.jve.2024.100441","DOIUrl":"10.1016/j.jve.2024.100441","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 32-33"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Severi, D. Bercow, K. Stallings, A. Criswell, F. Pennino, R. Acosta, T. Yang, D. Claiborne
{"title":"6.2 – 00049 Multivalent CAR T Cell Therapy Shows Superior Potency in Controlling HIV Escape and Replication in BLT Humanized Mice","authors":"F. Severi, D. Bercow, K. Stallings, A. Criswell, F. Pennino, R. Acosta, T. Yang, D. Claiborne","doi":"10.1016/j.jve.2024.100425","DOIUrl":"10.1016/j.jve.2024.100425","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 21"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S.M. Jablonski, J.A. Jablonski, L. Shuang, L. Ling, A.T. McAuley, R. Ronald Jr, P. Espinoza-Gonzales, B. MacTavish, Q. Gibault, S. Zhang, T. Bannister, S.M. Schader, R. Ptak, V. Garcia, C. Augelli-Szafran, S.T. Valente
{"title":"3.1 – 00145 Exploring novel HIV Tat inhibitors","authors":"S.M. Jablonski, J.A. Jablonski, L. Shuang, L. Ling, A.T. McAuley, R. Ronald Jr, P. Espinoza-Gonzales, B. MacTavish, Q. Gibault, S. Zhang, T. Bannister, S.M. Schader, R. Ptak, V. Garcia, C. Augelli-Szafran, S.T. Valente","doi":"10.1016/j.jve.2024.100406","DOIUrl":"10.1016/j.jve.2024.100406","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 8-9"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ST2.4 – 00035 Bach controls seeding of HIV reservoirs in memory CD4+ T cells","authors":"L. Shan","doi":"10.1016/j.jve.2024.100449","DOIUrl":"10.1016/j.jve.2024.100449","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Pages 38-39"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143179384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Cronin, A.P. Casanova, Z. Vahlas, E. Lee, K. Fisher, A. de Vries-Egan, M. Sharabas, A. Kelleher, C. Vérollet, L. Balboa, S. Palmer, G. Duette
{"title":"7.6 – 00052 The Tuberculosis Associated Microenvironment Reduces CD8+ TCell Control of HIV at the Site of the Coinfection","authors":"S. Cronin, A.P. Casanova, Z. Vahlas, E. Lee, K. Fisher, A. de Vries-Egan, M. Sharabas, A. Kelleher, C. Vérollet, L. Balboa, S. Palmer, G. Duette","doi":"10.1016/j.jve.2024.100435","DOIUrl":"10.1016/j.jve.2024.100435","url":null,"abstract":"","PeriodicalId":17552,"journal":{"name":"Journal of Virus Eradication","volume":"10 ","pages":"Page 28"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143181177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}