Journal of Tropical Pediatrics最新文献

Frequency and predictors of red blood cell transfusion in the pediatric intensive care unit: a prospective observational study. 儿科重症监护室输注红细胞的频率和预测因素：一项前瞻性观察研究。

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmaf004

Surya Kant Tiwari, Jomol Rajesh, Neethu Mariya Mathew, Nitin Dhochak, Rakesh Lodha, Poonam Joshi

{"title":"Frequency and predictors of red blood cell transfusion in the pediatric intensive care unit: a prospective observational study.","authors":"Surya Kant Tiwari, Jomol Rajesh, Neethu Mariya Mathew, Nitin Dhochak, Rakesh Lodha, Poonam Joshi","doi":"10.1093/tropej/fmaf004","DOIUrl":"https://doi.org/10.1093/tropej/fmaf004","url":null,"abstract":"Red blood cell (RBC) transfusion is crucial in treating anemia in the pediatric intensive care unit (PICU), though safety and necessity concerns persist. This prospective observational study examined the frequency and predictors of RBC transfusions among critically ill children, highlighting implications for low- and middle-income countries (LMICs). A single-center observational study enrolled 104 children admitted to a PICU from January to September 2021. Demographic details, past medical history, Pediatric Index of Mortality-3 scores, sedation, inotrope administration, ventilator-associated pneumonia (VAP), new-onset shock, respiratory failure, sepsis, renal failure, new or progressive multiple organ dysfunction syndrome (MODS), and duration of ventilation were recorded. Our results showed that 37 patients (35.6%) received RBC transfusions. The mean pre-transfusion hemoglobin level was 6.58 grams per deciliter (g/dl) (SD 1.71). The transfused group required more sedation (P < .001) and vasoactive agents (P < .001), had longer PICU stays (P = .013), and developed VAP (P = .037), new-onset shock (P = .025), respiratory failure (P = .021), and MODS (P = .023) more often than the non-transfused group. Logistic regression analysis showed that hemoglobin >10 g/dl at admission reduced the odds of RBC transfusion [odds ratio (OR) = 0.57, confidence interval (CI) = 0.43-0.74], while sepsis at admission increased the odds (OR = 3.24, CI = 1.09-9.60). The current study demonstrates that about one-third of critically ill children received RBC transfusions. Hemoglobin above 10 g/dl at admission was associated with significantly lower odds of RBC transfusion, while sepsis at admission significantly increased the odds. These findings are particularly relevant for LMICs, where resource constraints necessitate careful evaluation of transfusion practices to optimize patient outcomes and resource utilization.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seroprevalence of SARS-CoV-2 infection among hospitalized children at a tertiary care center in North-East India.

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmaf007

Chabungbam Smilie, Sareet Kumari Nandeibam, Chongtham Shyamsunder Singh, Khuraijam Ranjana Devi, Yendrembam Bidyalakshmi Devi, Yumlembam Bishwabati Devi, Ngamba Akham, Sareet Laxmi Nandeibam

{"title":"Seroprevalence of SARS-CoV-2 infection among hospitalized children at a tertiary care center in North-East India.","authors":"Chabungbam Smilie, Sareet Kumari Nandeibam, Chongtham Shyamsunder Singh, Khuraijam Ranjana Devi, Yendrembam Bidyalakshmi Devi, Yumlembam Bishwabati Devi, Ngamba Akham, Sareet Laxmi Nandeibam","doi":"10.1093/tropej/fmaf007","DOIUrl":"https://doi.org/10.1093/tropej/fmaf007","url":null,"abstract":"To estimate the seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection among hospitalized children aged between 1 and 12 years. A cross-sectional study was conducted to determine the seroprevalence of SARS-CoV-2 antibodies among hospitalized children at a tertiary care hospital in the North-East region of India for a period of 13 months (October 2022-November 2023). The presence of SARS-CoV-2 antibodies was estimated using enzyme-linked immunosorbent assay method. Sociodemographic characteristics and clinical profile of the participants were analyzed. The seroprevalence of SARS-CoV-2 infection among hospitalized children aged between 1 and 12 years was estimated to be 98.4%. This was comparable for children between the age groups 1-5 years (97.9%) and 6-12 years (99.1%) (P-value = .478). The most commonly reported symptoms among the seropositive children were fever (76.8%), nasal stuffiness (69.5%), cough (67.8%), diarrhea (23.6%), and nausea/vomiting (23.2%). None of the study participants had a prior history of laboratory confirmed coronavirus disease (COVID-19) infection in the past and none were vaccinated against COVID-19. Results of the univariate analysis showed that there was no significant difference between the seropositive and seronegative children in the distribution of sociodemographic characteristics, clinical profile, and laboratory findings. Our study observed a remarkably high anti-SARS-CoV-2 seropositivity rate of 98.4%, suggesting a significant under-recognized burden of COVID-19 in the pediatric population. The findings highlight the need for continued preventive measures and the development of age-appropriate vaccination strategies, particularly in tropical settings.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of nutritional supplementation with lipid-based therapeutic food on body composition of non-severely malnourished African children aged 6-59 months hospitalized with severe pneumonia.

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmaf010

Damalie Nalwanga, Victor Musiime, Sarah Kiguli, Peter Olupot-Olupot, Florence Alaroker, Robert Opoka, Abner Tagoola, Hellen Mnjala, Christabel Mogaka, Eva Nabawanuka, Elisa Giallongo, Charles Karamagi, André Briend, Kathryn Maitland

{"title":"Effect of nutritional supplementation with lipid-based therapeutic food on body composition of non-severely malnourished African children aged 6-59 months hospitalized with severe pneumonia.","authors":"Damalie Nalwanga, Victor Musiime, Sarah Kiguli, Peter Olupot-Olupot, Florence Alaroker, Robert Opoka, Abner Tagoola, Hellen Mnjala, Christabel Mogaka, Eva Nabawanuka, Elisa Giallongo, Charles Karamagi, André Briend, Kathryn Maitland","doi":"10.1093/tropej/fmaf010","DOIUrl":"https://doi.org/10.1093/tropej/fmaf010","url":null,"abstract":"Pneumonia remains an important cause of morbidity and mortality among children in low- and middle-income countries. Poor outcomes are associated with undernutrition. Nutritional supplementation may be beneficial. We examined the effect of supplementation with lipid-based ready-to-use therapeutic food (RUTF) on the body composition of children with severe pneumonia. Non-severely malnourished children (6-59 months) with severe pneumonia enrolled into the Children's Oxygen Administration Strategies and Nutrition trial in Uganda and Kenya, and randomized to receive a diet supplemented with RUTF (500 Kcal/day) for 56 days versus usual diet alone (control) were included. We assessed arm anthropometry and bioimpedance analysis at admission and days 28, 90, and 180 of follow-up. We used mixed effects linear regression to compare body composition between groups. We included 737 participants (369 in intervention; 368 in control group). The median age was 16 months (IQR; 9, 26), and 58.1% were male. Overall, baseline mean arm fat area (AFA), arm muscle area, and arm muscle circumference were 5.8 ± 1.8 cm2, 11.6 ± 2.3 cm2, and 12.3 ± 1.2 cm2, respectively. The mean fat mass and fat-free mass calculated in 116 participants were 5.5 ± 1.5 kg and 5.5 ± 1.5 kg, respectively. There were modest increases in most body composition parameters. RUTF significantly increased AFA at days 28 and 90 but not at day 180 (P-value = .03, .02, and .99, respectively). RUTF did not change other body composition parameters. Despite initial increases in AFA, RUTF did not change the body composition of children with severe pneumonia.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colistin-resistant Klebsiella pneumoniae sepsis in neonates and infants: an alarming crisis in an Indian NICU.

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmae044

Sushil Kumar, Akanksha Verma, Anita Singh, Kirti M Naranje, Richa Misra

{"title":"Colistin-resistant Klebsiella pneumoniae sepsis in neonates and infants: an alarming crisis in an Indian NICU.","authors":"Sushil Kumar, Akanksha Verma, Anita Singh, Kirti M Naranje, Richa Misra","doi":"10.1093/tropej/fmae044","DOIUrl":"https://doi.org/10.1093/tropej/fmae044","url":null,"abstract":"Emergence of multidrug-resistant strain of Klebsiella pneumoniae has led to limited number of antimicrobial options for treatment. Even though outbreaks of colistin-carbapenem-resistant K. pneumoniae (CCRKp) are evolving, reported literature is scarce. This is a retrospective case series of three infants who acquired CCRKp sepsis during an outbreak in a Level III neonatal intensive care unit (NICU) of a tertiary care centre in Northern India. Data were retrieved from medical records of patients. Three babies developed new onset clinical worsening during an outbreak of sepsis. All had respiratory comorbidities and previous antibiotic exposure prior to isolation of CCRKp sepsis from blood. The organism was sensitive to combination of ceftazidime plus avibactam and tetracyclines in two infants; in one other newborn, no sensitive antibiotic was found. Two neonates deceased due to multiorgan dysfunction. An outbreak investigation revealed one common source of sterile water used in a humidifier. The outbreak was resolved by temporarily closing the NICU, segregating the infected infants and using corrective measures such as procuring a fresh batch of sterile water bottles, disinfecting the NICU, and reinforcing the use of antiseptic techniques. The emergence of CCRKp is alarming, particularly in low- and middle-income countries and tropical regions where such outbreaks are difficult to control due to limited healthcare infrastructure. These findings highlight the urgent need for stringent antimicrobial stewardship practices, enhanced infection control, and tailored interventions in resource-limited settings. It is also to be emphasized that the main mechanism of carbapenem resistance in Kp organisms in Asia seems to be different from the West and is mainly mediated by metallo-beta-lactamases and Class D carbapenemases.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluid restriction for term infants with hypoxic-ischemic encephalopathy following perinatal asphyxia-a randomized controlled trial.

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmaf009

Anitha Ananthan, Haribalakrishna Balasubramanian, Ruchi Nanavati, Prashanth Raghavendra

{"title":"Fluid restriction for term infants with hypoxic-ischemic encephalopathy following perinatal asphyxia-a randomized controlled trial.","authors":"Anitha Ananthan, Haribalakrishna Balasubramanian, Ruchi Nanavati, Prashanth Raghavendra","doi":"10.1093/tropej/fmaf009","DOIUrl":"https://doi.org/10.1093/tropej/fmaf009","url":null,"abstract":"Fluid management in the first postnatal week among infants with perinatal asphyxia and hypoxic-ischemic encephalopathy (HIE) is an important knowledge gap. We aimed to evaluate the effects of fluid restriction on short- and long-term outcomes in infants with HIE. Term infants with moderate or severe HIE on therapeutic hypothermia were randomized within 6 hours of age to receive either restricted intravenous maintenance fluids (45 ml/kg/day on day 1 to a maximum of 120 ml/kg/day on day 6) vs conventional fluid (60 ml/kg/day on day 1 to a maximum of 150 ml/kg/day on day 6). The primary outcome was a composite of mortality or neurological abnormality at hospital discharge. We studied neurodevelopmental disability at 18-24 months using Bayley Scales of Infant Development, third edition. A total of 210 infants were randomized. Three infants died during the hospital stay. The primary outcome of mortality or neurological abnormality at discharge was not significantly different between the restricted and the conventional fluid group [57% vs 53%, RR: 1.07 (95% CI: 0.83, 1.37), P-value .58]. The incidence of cranial magnetic resonance imaging abnormalities was similar in the groups (65% vs 71%, P-value .30). There were no differences in the rates of severe neurodevelopmental disability at 18-24 months in the two groups [27% vs 28%, RR: 0.96 (95% CI: 0.62, 1.50), P-value .88]. Adverse outcomes were similar in both groups. Fluid restriction in the first postnatal week of life did not improve short- and long-term neurodevelopmental outcomes in term infants with moderate or severe HIE.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous positive airway pressure versus conventional oxygen therapy in meconium aspiration syndrome: a randomized controlled trial.

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmaf002

Arifa Mustaqeem, Anita Yadav, Jogender Kumar, Pradeep Debata

引用次数: 0

Evaluating the efficacy of very high-dose oral prednisolone in West syndrome: in Uttar Pradesh, India, a resource-limited setting.

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmaf005

Chandra Prabha, Chandra Kanta, Arpita Bhriguvanshi, Sanjeev Kumar Verma

{"title":"Evaluating the efficacy of very high-dose oral prednisolone in West syndrome: in Uttar Pradesh, India, a resource-limited setting.","authors":"Chandra Prabha, Chandra Kanta, Arpita Bhriguvanshi, Sanjeev Kumar Verma","doi":"10.1093/tropej/fmaf005","DOIUrl":"https://doi.org/10.1093/tropej/fmaf005","url":null,"abstract":"Managing West syndrome (WS) becomes arduous in regions where access to adrenocorticotropic hormone and vigabatrin is limited, particularly in developing nations. This study aimed to evaluate the efficacy of very high-dose oral prednisolone in children diagnosed with WS. Children aged 2-36 months presenting with WS were consecutively enrolled and given oral prednisolone @ 8 mg/kg/day (maximum 40 mg) for two weeks followed by tapering doses over the subsequent two weeks. Weekly follow-ups were conducted until therapy completion, followed by bi-weekly assessments for three months. Responses (primary outcome) were assessed at two weeks and categorized as complete (spasm-free), partial (>25% reduction), or no response (<25% reduction). Neurodevelopmental outcomes, clinical-radiological profiles, safety, and therapy response predictors were also assessed. Of the 80 children, 73.7% exhibited a complete response, while 21.2% and 5% showed partial and no response, respectively. The mean age at spasm onset and presentation was 4.98 ± 4.37 months and 14.36 ± 7.13 months, respectively. Perinatal brain injury accounted for 87.5% of WS cases. Adverse effects, including weight gain (8.7%), irritability, hypertension, and disturbed sleep (3.7% each), were noted. Spasm cessation at 2 weeks, appropriate gestational age, and the absence of other seizure types were predictive of a favorable response. High-dose oral prednisolone emerges as an effective, low-cost, and safer first-line treatment option with minimal adverse effects in the Uttar Pradesh region in India, and this would likely be true in other resource-limited settings.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Septic pulmonary embolism associated with Staphylococcus aureus: case series and review of the literature. 与金黄色葡萄球菌相关的化脓性肺栓塞：系列病例和文献综述。

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmaf008

Asena Ünal, Ulaş Özdemir, Nisanur Tapaç, Fatma Kılınç, Emel Bakanoğlu, Fatma Tuğba Çetin, Merve Kılıç Çil, Ümmühan Çay, Özlem Özgür Gündeşlioğlu, Rıza Dinçer Yıldızdaş, Ümit Çelik, Derya Alabaz

{"title":"Septic pulmonary embolism associated with Staphylococcus aureus: case series and review of the literature.","authors":"Asena Ünal, Ulaş Özdemir, Nisanur Tapaç, Fatma Kılınç, Emel Bakanoğlu, Fatma Tuğba Çetin, Merve Kılıç Çil, Ümmühan Çay, Özlem Özgür Gündeşlioğlu, Rıza Dinçer Yıldızdaş, Ümit Çelik, Derya Alabaz","doi":"10.1093/tropej/fmaf008","DOIUrl":"https://doi.org/10.1093/tropej/fmaf008","url":null,"abstract":"Septic pulmonary embolism (SPE) is a rare, life-threatening disease in children. We assessed the clinical, microbiological, radiological, and treatment results of patients who developed SPE due to Staphylococcus aureus (S. aureus). We retrospectively reviewed the medical records of patients with SPE associated with S. aureus between 2012 and 2023. Six patients were included in the study; the median age was 13 years (range: 9-16 years), and four (66.7%) of them were boys. At admission, the most common complaints were chest pain (83.3%), respiratory distress (83.3%), limb swelling (83.3%), limitation of movement in the extremities (83.3%), fever (50%), fatigue (50%), and cough (16.7%). Extrapulmonary septic foci were identified as follows: septic arthritis in four patients (66.7%), soft tissue infection in one patient (16.7%), and deep vein thrombosis in one patient (16.7%). Methicillin-resistant S. aureus was the most common causative pathogen (66.7%) and methicillin-susceptible S. aureus was found in 33% of patients. The median length of hospital stay was 43.5 days (range: 25-45 days). Three (50%) patients required intensive care, and one required mechanical ventilation support. No mortality was observed. In our study, the clinical and radiological features of staphylococcal SPE in children were nonspecific, similar to the literature. Although no mortality was observed in our study, previous studies have reported mortality rates of up to 11.8% in children with SPE. Early diagnosis, appropriate antibiotic treatment, and respiratory support are important in patients with SPE, especially in low-income settings where timely access to healthcare and diagnostic resources may be limited.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital syphilis: epidemiological profile of Brazilian regions in the last decade.

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2025-02-05 DOI: 10.1093/tropej/fmaf003

Maria Eugênia Costa Casagrande, Anderson Soares da Silva, Altacílio Aparecido Nunes

{"title":"Congenital syphilis: epidemiological profile of Brazilian regions in the last decade.","authors":"Maria Eugênia Costa Casagrande, Anderson Soares da Silva, Altacílio Aparecido Nunes","doi":"10.1093/tropej/fmaf003","DOIUrl":"https://doi.org/10.1093/tropej/fmaf003","url":null,"abstract":"Congenital syphilis (CS) is transmitted to the fetus through the transplacental route at any stage of gestation when the pregnant women are either untreated or inadequately treated. In this study, we aimed to analyze trends in epidemiological indicators of CS in Brazil. This is a cross-sectional study utilizing data on CS across Brazilian regions from 1 January 2012 to 31 December 2021. Epidemiological indicators such as incidence, prevalence, and case-fatality rates were calculated. During the evaluated period, 192 055 CS cases were recorded in Brazil. Among pregnant women who underwent prenatal care, 58.5% were diagnosed during pregnancy, 33.9% at the time of birth, and 7.5% after birth. In 77.5% of the notifications, the partners were not treated. The average number of cases diagnosed during prenatal care was 5.6 times higher than those not reported. The Southeast region presented the highest incidence rate per 1000 live births, whereas the Midwest region had the lowest incidence. Despite an increase in rates across all regions and Brazil overall, there was no significant difference (P-value > .05) between the means for the two evaluated periods. However, there was a significant decrease (P-value < .05) in the case-fatality rate in the Northeast (1.9%-1.25%) and South (2.15%-0.92%) regions, as well as throughout Brazil (from 1.77% to 1.24%). The findings indicate that the incidence rates of CS continue to rise, suggesting that the disease remains a significant public health issue in Brazil. Effective preventive measures are urgently required.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 2","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and associated factors of anaemia and iron-deficiency anaemia among adolescent Sudanese schoolchildren: a cross-sectional study. 苏丹青少年学童中贫血和缺铁性贫血的患病率及其相关因素：一项横断面研究。

IF 1.8 4区医学

Journal of Tropical Pediatrics Pub Date : 2024-12-05 DOI: 10.1093/tropej/fmae047

Hiba M Osman, Almarwa A Osman, Abdullah Al-Nafeesah, Ashwaq AlEed, Ishag Adam

{"title":"Prevalence and associated factors of anaemia and iron-deficiency anaemia among adolescent Sudanese schoolchildren: a cross-sectional study.","authors":"Hiba M Osman, Almarwa A Osman, Abdullah Al-Nafeesah, Ashwaq AlEed, Ishag Adam","doi":"10.1093/tropej/fmae047","DOIUrl":"https://doi.org/10.1093/tropej/fmae047","url":null,"abstract":"Anaemia among adolescents is a worldwide health problem; however, data on anaemia among adolescents in Sudan are scarce. A cross-sectional study was conducted to investigate the prevalence and associated factors of anaemia and iron-deficiency anaemia among adolescent schoolchildren in northern Sudan. Socio-demographic information was collected using a questionnaire. A total of 309 adolescents (52.4% female and 47.6% male) were enrolled in the study. Seventy-five (24.3%) adolescents had anaemia, and none had severe anaemia. In the multivariate analysis, history of pica [adjusted odds ratio (AOR) = 2.30, 95% confidence interval (CI) = 1.31-4.02] was associated with increased odds of anaemia, and an increased level of serum ferritin (AOR = 0.97, 95% CI = 0.95-0.99) was associated with decreased odds of anaemia. Of the adolescents, 189 (61.2%) and 55 (17.8%) had iron deficiency and iron-deficiency anaemia, respectively. In the multivariate analysis, being female (AOR = 3.13, 95% CI = 1.88-5.23) and having a history of pica (AOR = 1.85, 95% CI = 1.03-3.31) were associated with increased odds of iron deficiency. This study showed a high prevalence of anaemia and iron-deficiency anaemia among adolescents in this part of Sudan, which was associated with a history of pica.","PeriodicalId":17521,"journal":{"name":"Journal of Tropical Pediatrics","volume":"71 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0