宫内生长受限新生儿延迟脐带夹紧的效果评价。

IF 1.1 4区 医学 Q2 PEDIATRICS
Sabriye Korkut, Yüksel Oğuz, Davut Bozkaya, Şehribanu Işık, Demet Çam, Dilek Uygur, Sara Erol, Şerife Suna Oğuz
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引用次数: 0

摘要

目的探讨出生时延迟脐带夹紧(DCC)对诊断为宫内生长受限(IUGR)的新生儿的影响。这项前瞻性、随机、对照研究纳入妊娠随访期间诊断为IUGR且胎龄≥28周的新生儿。早期脐带夹紧(ECC)在出生后立即进行,而DCC在分娩后60 s进行。根据脐带血和24小时静脉红细胞压积水平、红细胞增多率和与红细胞增多症相关的临床并发症对ECC组和DCC组进行比较。分析96例新生儿,每组48例。两组妊娠周数、出生体重、Apgar评分、分娩方式、产妇特征相似(P < 0.05)。出生后24 h, DCC组的红细胞压积值(61.27%±5.93%)显著高于ECC组(57.42%±7.10%)(P = 0.005)。DCC组24小时红细胞增多率也较高(31.3%比12.5%,P = 0.02)。DCC组1例新生儿(2.1%)需要部分交换输血(PET)。两组患者呼吸窘迫、需要光疗的黄疸、头2天内低血糖、重症监护入院、需要密切监测的发生率相似(P < 0.05)。在IUGR新生儿中,出生时延迟脐带夹紧60秒导致静脉红细胞压积水平升高和红细胞增多率升高。需要更大规模的研究来阐明DCC是否影响PET的需要以及红细胞增多症相关临床并发症的频率和严重程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of the effects of delayed cord clamping in neonates with intrauterine growth restriction.

To assess the effects of delayed cord clamping (DCC) at birth on newborns diagnosed with intrauterine growth restriction (IUGR). This prospective, randomized, controlled study included newborns diagnosed with IUGR during pregnancy follow-up and born at a gestational age of ≥28 weeks. Early cord clamping (ECC) was performed immediately after birth, whereas DCC was performed 60 s postdelivery. The ECC and DCC groups were compared based on cord blood and 24-h venous hematocrit levels, polycythemia rates, and clinical complications associated with polycythemia. A total of 96 newborns, 48 in each group, were analyzed. Gestational weeks, birth weight, Apgar score, delivery mode, and maternal features were similar between the groups (P > .05). At 24 h postnatally, hematocrit values were significantly higher in the DCC group (61.27% ± 5.93%) compared to the ECC group (57.42% ± 7.10%) (P = .005). The 24-h polycythemia rate was also higher in the DCC group (31.3% vs. 12.5%, P = .02). Partial exchange transfusion (PET) was required for one neonate in the DCC group (2.1%). The rates of respiratory distress, phototherapy-requiring jaundice, hypoglycemia within the first two days, intensive care admission, and need for close monitoring were similar between the groups (P > .05). In neonates with IUGR, delayed cord clamping for 60 s at birth led to increased venous hematocrit levels and a higher polycythemia rate. Larger studies are warranted to clarify whether DCC influences the need for PET and the frequency or severity of polycythemia-associated clinical complications.

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来源期刊
Journal of Tropical Pediatrics
Journal of Tropical Pediatrics 医学-热带医学
CiteScore
4.00
自引率
0.00%
发文量
97
审稿时长
6-12 weeks
期刊介绍: The Journal of Tropical Pediatrics provides a link between theory and practice in the field. Papers report key results of clinical and community research, and considerations of programme development. More general descriptive pieces are included when they have application to work preceeding elsewhere. The journal also presents review articles, book reviews and, occasionally, short monographs and selections of important papers delivered at relevant conferences.
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