Journal of traumatic stress最新文献_第5页

Enhancing cognitive processing therapy via stellate ganglion blocks: A pilot randomized trial. 通过星状神经节阻滞增强认知加工治疗：一项试点随机试验。

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-14 DOI: 10.1002/jts.70116

Philip Held, Sarah A Pridgen, Dale L Smith, Daniel R Szoke, Asokumar Buvanendran, Robert J McCarthy

{"title":"Enhancing cognitive processing therapy via stellate ganglion blocks: A pilot randomized trial.","authors":"Philip Held, Sarah A Pridgen, Dale L Smith, Daniel R Szoke, Asokumar Buvanendran, Robert J McCarthy","doi":"10.1002/jts.70116","DOIUrl":"https://doi.org/10.1002/jts.70116","url":null,"abstract":"Although trauma-focused psychotherapies, such as cognitive processing therapy (CPT), are effective treatments for posttraumatic stress disorder (PTSD), a substantial portion of individuals exhibit a diminished response. Stellate ganglion block (SGB), an anesthetic procedure targeting the sympathetic nervous system, has shown promise for PTSD but has only recently begun to be evaluated as an augmentation to evidence-based psychotherapy. This randomized, placebo-controlled, double-blind pilot trial assessed the efficacy of 1-week accelerated CPT augmented with SGB versus a placebo injection. Of 54 consented individuals, 39 participants (Mage = 38.1 years, SD = 11.0; 69.2% female; 79.5% White) who met the DSM-5 criteria for PTSD were randomized to receive SGB (n = 18) or a saline injection (n = 21), followed by 10 virtual CPT sessions over 5 days. The primary outcome was clinician-assessed PTSD severity (Clinician-Administered PTSD Scale for DSM-5; CAPS-5); secondary outcomes included self-reported PTSD (PTSD Checklist for DSM-5; PCL-5) and depressive symptoms (Patient Health Questionnaire-9; PHQ-9). Of 39 randomized participants, 37 (94.9%) completed treatment. Both groups experienced large improvements in PTSD symptoms, CAPS-5 (baseline-3-months): d = 1.77, PCL-5: d = 1.67, and depressive symptoms, PHQ-9: d = 0.86. Treatment Condition x Time interactions were not significant for the CAPS-5, PCL-5, or PHQ-9, ps = .144-.958. Post hoc comparisons indicated significantly lower PCL-5 scores in the SGB group on Day 1 of CPT, B = -11.99, p = .015. Augmenting accelerated CPT with SGB was highly feasible but did not produce significantly larger symptom reductions compared to placebo.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structurally competent care for families facing the continuous traumatic stress of community violence and systemic racism. 为面临社区暴力和系统性种族主义造成的持续创伤压力的家庭提供结构上合格的护理。

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-05 DOI: 10.1002/jts.70113

Bradley C Stolbach, Seeba Anam, Keyona Allen, Emma-Lorraine Baaba Bart-Plange, Royce Lee, Aashana Daru, Angel Boulware, Sonya Mathies Dinizulu

引用次数: 0

Effects of continuous traumatic stress and coping efficacy on mental health outcomes during an ongoing war in Ukraine. 乌克兰持续战争期间持续创伤应激和应对效能对心理健康结果的影响。

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-05 DOI: 10.1002/jts.70115

Iryna Frankova, Kathryn S Macia, Kimberly K Ecker, Kayleigh N Watters, Leah Danson, Monika Fňašková, Daija Jackson, Iryna Leshchuk, Tolou Maslahati, Vuyokazi Ntlantsana, Jenna Sanfilippo, Arieh Y Shalev

{"title":"Effects of continuous traumatic stress and coping efficacy on mental health outcomes during an ongoing war in Ukraine.","authors":"Iryna Frankova, Kathryn S Macia, Kimberly K Ecker, Kayleigh N Watters, Leah Danson, Monika Fňašková, Daija Jackson, Iryna Leshchuk, Tolou Maslahati, Vuyokazi Ntlantsana, Jenna Sanfilippo, Arieh Y Shalev","doi":"10.1002/jts.70115","DOIUrl":"https://doi.org/10.1002/jts.70115","url":null,"abstract":"War profoundly affects the well-being of civilian populations and shapes subsequent mental health outcomes. This study aimed to investigate the effects of continuous traumatic stress (CTS) and coping efficacy on mental health outcomes among adults in Ukraine amid ongoing warfare over time. We examined how changes in CTS responses, coping efficacy, and stressful life events predicted posttraumatic stress disorder (PTSD) symptoms and broad mental health outcomes (depression, anxiety, insomnia, well-being). Participants were 157 adults who experienced war-related stress and completed two online surveys approximately 12 months apart. Moderately small but significant symptom reductions were observed, ds = 0.18-0.32, ps = .005-.026. Structural equation models analyzing the associations between initial status and changes in CTS, coping efficacy, and stressful life events and Time 2 PTSD symptoms and broad mental health outcomes explained most of the variance in PTSD symptoms and broad mental health outcomes, R2 = .84‒.85. Higher initial severity and worsening CTS responses over time predicted higher PTSD symptom severity, standardized estimate (Eststd) = 0.29‒0.32, ps = .001‒.006, and poorer broad mental health outcomes, Eststd = 0.25‒0.28, ps = .001‒.016. Increased stressful life event exposure was linked to worse broad mental health outcomes, Eststd = 0.16, p = .001. Improvements in coping efficacy predicted superior broad mental health outcomes, Eststd = -0.43, p < .001. Assessing and addressing the impact of CTS, considering the toll of stressful life events, and enhancing coping efficacy may help to optimize service delivery in ongoing war environments.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of written exposure therapy for reducing depressive symptoms in individuals with posttraumatic stress disorder: A systematic review. 书面暴露疗法减轻创伤后应激障碍患者抑郁症状的有效性：一项系统综述

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-05 DOI: 10.1002/jts.70114

Eunice Tao, Bruce Arroll, Andrew Jull, Fiona Moir, Rachel Roskvist, Nicholas Hoeh, Ranche Johnson, Nika Nova

{"title":"Effectiveness of written exposure therapy for reducing depressive symptoms in individuals with posttraumatic stress disorder: A systematic review.","authors":"Eunice Tao, Bruce Arroll, Andrew Jull, Fiona Moir, Rachel Roskvist, Nicholas Hoeh, Ranche Johnson, Nika Nova","doi":"10.1002/jts.70114","DOIUrl":"https://doi.org/10.1002/jts.70114","url":null,"abstract":"Written exposure therapy (WET) has become increasingly recognized alongside other evidence-based treatments of posttraumatic stress disorder (PTSD), with a rapidly growing evidence base. However, current research has not yet investigated the effect of WET on comorbid depression. We conducted a systematic review to examine the efficacy of WET for comorbid depression among PTSD populations. The primary aim of this review was to investigate WET's effectiveness in reducing depression at posttreatment and follow-up. A review of five major databases, with no language or publication date restrictions, yielded 18 papers that met all inclusion criteria. Due to variability among studies, including study design, population studied, and modifications to WET, we integrated the current literature descriptively. The individual study findings reported an overall reduction in depressive symptoms, with within-group effect sizes ranging from small to large, ds = 0.39-1.43. The noninferiority randomized controlled trial included in the review found that WET was comparable to CPT, d = 0.19. These findings suggest that WET may be effective for reducing depressive symptoms in PTSD populations, and future trials should measure and report depression outcomes to contribute to the WET literature.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148679177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oppression-based stressors, posttraumatic stress symptoms, and self-injurious thoughts and behaviors among a national sample of queer adolescents of color 全国有色人种酷儿青少年样本中基于压迫的压力源、创伤后应激症状和自残思想与行为。

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-04 Epub Date: 2026-04-22 DOI: 10.1002/jts.70069

Tara R. Sullivan, Marianna Amato, Jeremy T. Goldbach, Ethan H. Mereish

{"title":"Oppression-based stressors, posttraumatic stress symptoms, and self-injurious thoughts and behaviors among a national sample of queer adolescents of color","authors":"Tara R. Sullivan, Marianna Amato, Jeremy T. Goldbach, Ethan H. Mereish","doi":"10.1002/jts.70069","DOIUrl":"10.1002/jts.70069","url":null,"abstract":"Oppression-based stressors (OBS; e.g., heterosexism-based stressors) are associated with a higher risk of trauma-related symptoms and self-injurious thoughts and behaviors (SITB) for queer (e.g., lesbian, gay, bisexual) adolescents. However, prior research has yet to examine posttraumatic stress symptoms (PTSS) and SITB in the context of the unique, intersectional OBS experienced by queer adolescents who are also Black, Indigenous, and/or people of color (BIPOC). This study examined the associations among intersectional OBS, PTSS, and SITB and tested identity outness as a potential moderator of these associations. A national sample of 1,009 queer BIPOC adolescents (Mage = 15.97 years, SD = 0.93; 62.0% cisgender girls, 50.1% plurisexual) was recruited online. After accounting for sociodemographic characteristics and overall perceived stress, OBS, β = .08, and identity outness, β = .08, were significantly associated with higher PTSS. OBS and identity outness were also associated with a higher likelihood of endorsing all three suicide outcomes (suicidal ideation, suicide planning, and suicide attempts), adjusted odds ratios (aORs) = 1.35 and 1.55, respectively, as well as a higher likelihood of nonsuicidal self-injury, aORs = 1.22 and 1.21. Identity outness did not serve as a moderator in the associations among OBS, PTSS, and SITB. The findings suggest that intersectional OBS may serve as a risk factor for PTSS and severe levels of SITB among queer BIPOC adolescents. Further research is needed to identify the unique role of outness among queer BIPOC adolescents and additional factors that may protect against the negative mental health outcomes associated with OBS.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":"39 4","pages":"655-662"},"PeriodicalIF":3.4,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jts.70069","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147775188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transness is our salve: How trans identity facilitates healing from relational trauma with parental figures 变性是我们的良药：变性身份如何促进与父母关系创伤的愈合。

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-04 Epub Date: 2026-01-28 DOI: 10.1002/jts.70044

Joonwoo Lee, Sebastian Barr, Alberta M. Gloria, Tonya J. Roberts, Stephanie L. Budge

{"title":"Transness is our salve: How trans identity facilitates healing from relational trauma with parental figures","authors":"Joonwoo Lee, Sebastian Barr, Alberta M. Gloria, Tonya J. Roberts, Stephanie L. Budge","doi":"10.1002/jts.70044","DOIUrl":"10.1002/jts.70044","url":null,"abstract":"Transgender and nonbinary (TNB) individuals experience high rates of relational trauma from parental figures, yet their pathways to healing remain underexplored. This qualitative study used constructivist grounded theory to develop a theoretical framework of how TNB adults heal from parental relational trauma. In-depth interviews with 15 racially and socioeconomically diverse U.S.-based TNB adults who experienced parental relational trauma generated the core phenomenon: “TNB identity and experiences initiate and sustain pathways of healing from parental relational trauma.” This captures that rather than being a source of this trauma, recognizing and actualizing one's TNB identity is the central catalyst for healing from it. The healing process began with three conditions: (a) connecting with one's TNB identity/self, (b) gaining new clarity in parental harm through TNB-related parental harm, and (c) experiencing joy and oppression as TNB while lacking parental support. These conditions gave rise to strategies including (d) creating safer homes through queer/TNB chosen family, (e) committing to individual healing through therapy, and (f) reimagining life through ongoing actualization as TNB. The consequences of these strategies, in turn, created conditions that enabled subsequent strategies, including (g) attempting repair and intergenerational work with families of origin, (h) distancing as self-preservation, and (i) returning to TNB communities to sustain healing across generations. The consequences of these processes included personal, intergenerational, and collective healing. The study offers implications for research, clinical practice, and advocacy, calling for approaches that frame TNB identity not as a source of familial conflict but as a central resource for recovery.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":"39 4","pages":"616-628"},"PeriodicalIF":3.4,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jts.70044","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146064469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sexual orientation differences in trauma exposure and posttraumatic stress symptoms among adults in treatment for obsessive–compulsive disorder 成人强迫症治疗中创伤暴露和创伤后应激症状的性取向差异。

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-04 Epub Date: 2026-06-04 DOI: 10.1002/jts.70082

Andreas Bezahler, Nathaniel Van Kirk, Brian A. Feinstein, Martha J. Falkenstein, Jennie M. Kuckertz

{"title":"Sexual orientation differences in trauma exposure and posttraumatic stress symptoms among adults in treatment for obsessive–compulsive disorder","authors":"Andreas Bezahler, Nathaniel Van Kirk, Brian A. Feinstein, Martha J. Falkenstein, Jennie M. Kuckertz","doi":"10.1002/jts.70082","DOIUrl":"10.1002/jts.70082","url":null,"abstract":"Sexual minority individuals are at increased risk for developing mental health disorders, including obsessive–compulsive disorder (OCD) and posttraumatic stress disorder (PTSD). Prior research has identified that individuals with comorbid OCD and PTSD may have a more complex clinical presentation and worse treatment outcomes. Although PTSD is not the main focus of exposure with response prevention (ERP), the first-line therapy for OCD, symptoms are inadvertently targeted through overlapping mechanisms with exposure-based PTSD treatments. No prior research has compared sexual minority and heterosexual individuals receiving treatment for OCD regarding trauma history and posttraumatic stress symptom (PTSS) treatment outcomes. Participants (N = 696) included heterosexual (n = 554, 80.0%); bisexual, pansexual, and/or queer (bi+ ; n = 87, 13.0%); gay/lesbian (n = 39, 5.6%); and asexual (n = 16, 2.3%) adults in treatment for OCD and related disorders. Sexual minority participants were significantly more likely to report experiencing an interpersonal traumatic event compared to heterosexual participants, χ2(1, N = 695) = 5.97, p = .015. No significant differences were identified regarding noninterpersonal trauma, χ2(1, N = 695) = 0.84, p = .360. Further, bi+ participants reported significantly higher PTSS at baseline compared to heterosexual participants, but gay/lesbian and asexual participants did not differ from heterosexual participants. Participants reported significantly improved PTSS while receiving ERP, and this did not differ by sexual minority status. Clinical implications include assessing trauma among sexual minority patients, especially bi+ individuals; utilizing trauma-informed care; and incorporating sexual minority stressors into treatment for OCD.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":"39 4","pages":"677-688"},"PeriodicalIF":3.4,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148163839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between health care access and posttraumatic stress disorder symptoms among rural and urban lesbian, gay, bisexual, transgender, and queer adults 农村和城市女同性恋、男同性恋、双性恋、变性人和酷儿成人中医疗保健获取与创伤后应激障碍症状的关系

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-04 Epub Date: 2026-02-07 DOI: 10.1002/jts.70039

Emily A. Kenyon, Michelle A. Stage, Reina Kiefer, Mollie A. Ruben, Nicholas A. Livingston, Danielle S. Berke, Jillian C. Shipherd

{"title":"Associations between health care access and posttraumatic stress disorder symptoms among rural and urban lesbian, gay, bisexual, transgender, and queer adults","authors":"Emily A. Kenyon, Michelle A. Stage, Reina Kiefer, Mollie A. Ruben, Nicholas A. Livingston, Danielle S. Berke, Jillian C. Shipherd","doi":"10.1002/jts.70039","DOIUrl":"10.1002/jts.70039","url":null,"abstract":"Lesbian, gay, bisexual, transgender, and queer (LGBTQ+) individuals experience elevated rates of trauma exposure, minority stress, and posttraumatic stress disorder (PTSD). Yet, research examining how geographic location and LGBTQ+ identity shape PTSD outcomes is scant, particularly studies considering structural facilitators and barriers, such as health care access. This cross-sectional, secondary study investigated associations between several individual- and structural-level factors and PTSD symptoms in LGBTQ+ adults (N = 131) recruited from urban and rural U.S. regions, most of whom identified as non-Hispanic White, bisexual, cisgender women. Analyses examined whether intersecting demographic characteristics, urban or rural location, perceived health care access, LGBTQ+ identity disclosure to providers, and experiences of LGBTQ+ discrimination were associated with PTSD symptom severity and probable PTSD diagnosis. Approximately 62% of participants reported experiencing a DSM-5 Criterion A traumatic event; of these individuals, 24.4% met the criteria for probable PTSD. General health care access, β = −.27, 95% CI [−.45, −.09], p = .003, and LGBTQ+ identity disclosure, β = −.19, 95% CI [−.31, −.07], p = .039, were significantly associated with PTSD symptom severity. Higher health care access was associated with 50.0% lower odds of probable PTSD, ORadj = 0.50, 95% CI [0.29, 0.84], p = .009. Bisexual cisgender women had 4-times higher odds of a probable PTSD diagnosis compared to LGQ+ participants, ORadj = 3.96, 95% CI [1.15, 13.7], p = .030. Improving access to health care and supporting identity disclosure may reduce PTSD risk among LGBTQ+ adults, especially for bisexual cisgender women and rurally situated individuals.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":"39 4","pages":"663-676"},"PeriodicalIF":3.4,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examining stressful life experiences as risk factors for self-injurious behaviors as a function of sexual minority status in adults 研究压力生活经历作为成人性少数群体自残行为的风险因素。

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-04 Epub Date: 2026-06-12 DOI: 10.1002/jts.70096

Samantha M. Haas, Naomi Sadeh

{"title":"Examining stressful life experiences as risk factors for self-injurious behaviors as a function of sexual minority status in adults","authors":"Samantha M. Haas, Naomi Sadeh","doi":"10.1002/jts.70096","DOIUrl":"10.1002/jts.70096","url":null,"abstract":"Self-injurious behaviors (SIBs) represent a major public health concern in the United States. Although sexual minority individuals experience disproportionately high rates of SIBs, research identifying population-specific risk factors remains limited. This study examined how stressful experiences common among sexual minority (SM) adults relate to the likelihood of SIBs in SM versus heterosexual adults. A community sample of adults aged 18–54 years (Mage = 30.52 years, SD = 9.66, 59.8% assigned female at birth) completed self-report and interview measures of trait-level SIB risk factors (emotional reactivity, disinhibition), stressful life experiences (childhood trauma, discrimination), and lifetime history of nonsuicidal self-injury (NSSI) and suicide attempts. One third of participants (33.3%) reported SM attraction, 48.2% identified as a racial/ethnic minority, and 42.3% earned a high school diploma or less. A substantial minority reported a history of NSSI (24.1%) and/or a suicide attempt (12.4%). SM versus heterosexual attraction was associated with both NSSI, r = .36, p < .001, and suicide attempts, r = .25, p < .001, at the bivariate level. SM attraction moderated the link between discrimination and the odds of a suicide attempt, OR = 4.10, p = .030, such that discrimination was positively associated with the odds of a suicide attempt among SM, p = .008, but not heterosexual participants, p = .643. These findings highlight that everyday discrimination exerts a disproportionate impact on the risk of suicide attempts among SM adults, emphasizing the importance of interventions that confront discrimination and minority stressors to mitigate these disparities.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":"39 4","pages":"689-701"},"PeriodicalIF":3.4,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jts.70096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148226125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inclusion of sexual- and gender-minoritized individuals in randomized clinical trials of first-line treatments for posttraumatic stress disorder: A systematic literature review 在创伤后应激障碍一线治疗的随机临床试验中纳入性和性别少数个体：系统的文献综述。

IF 3.4 3区医学

Journal of traumatic stress Pub Date : 2026-08-04 Epub Date: 2026-01-19 DOI: 10.1002/jts.70043

Marley Warren, Lia J. Smith, Sarah A. Pridgen, Philip Held

{"title":"Inclusion of sexual- and gender-minoritized individuals in randomized clinical trials of first-line treatments for posttraumatic stress disorder: A systematic literature review","authors":"Marley Warren, Lia J. Smith, Sarah A. Pridgen, Philip Held","doi":"10.1002/jts.70043","DOIUrl":"10.1002/jts.70043","url":null,"abstract":"Clinical treatment guidelines consistently recommend cognitive processing therapy (CPT), prolonged exposure (PE), and eye movement desensitization and reprocessing (EMDR) for posttraumatic stress disorder (PTSD). The efficacy of these interventions among sexual- and/or gender-minoritized (SGM) individuals has not been thoroughly investigated within randomized clinical trials (RCTs), despite known elevations in exposure to potentially traumatic events and PTSD symptoms relative to cisgender heterosexual individuals. We conducted a systematic literature review to examine the frequency with which SGM adults were enrolled in RCTs of CPT, PE, and EMDR and investigate these interventions’ efficacy in reducing PTSD symptoms among SGM adults. We searched eight databases to identify RCTs published before August 7, 2025. The inclusion criteria were: written in English; RCT investigating the impact of CPT, PE, or EMDR on PTSD symptoms; utilized a standardized PTSD measure; reported PTSD outcome data; and enrolled individuals who were at least 18 years old. Literature reviews, case studies, protocols, and non–peer reviewed articles were excluded. Our search returned 1,821 unique records, with 519 meeting all eligibility criteria. Ten records reported sexual orientation and gender identity (SOGI) information and enrolled at least one SGM individual. Among studies that reported SOGI information, 12.1% and 2.2% of participants identified as sexual- and gender-minoritized, respectively. Results highlight that SOGI information is underreported in PTSD treatment research, posing significant challenges in determining the relative efficacy of these treatments and the extent to which SGM-affirmative adaptations are necessary. We offer recommendations for clinicians and researchers, including consistent reporting of full SOGI data.","PeriodicalId":17519,"journal":{"name":"Journal of traumatic stress","volume":"39 4","pages":"716-729"},"PeriodicalIF":3.4,"publicationDate":"2026-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146003788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0