Journal of The Serbian Chemical Society最新文献_第10页

The RP-HPLC method for analysis of usnic acid as potential marker of herbal drugs-based formulations containing Usnea barbata 采用反相高效液相色谱法分析山茱萸中药制剂中山茱萸酸的潜在标记物

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc201216045t

V. Tadić, A. Zugic, S. Djordjevic, I. Zizović, I. Homšek, D. Mišić, I. Nešić

引用次数: 3

Synthesis of novel fluorinated 1,5-benzothiazepine derivatives and their biological evaluation as anticancer and antibacterial agent 新型氟化1,5-苯并噻唑类衍生物的合成及其抗癌、抗菌生物学评价

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc210428041b

Sonal Bhabal, S. Shaikh, Ishita Yellapurkar, G. Pavale, M. Ramana

{"title":"Synthesis of novel fluorinated 1,5-benzothiazepine derivatives and their biological evaluation as anticancer and antibacterial agent","authors":"Sonal Bhabal, S. Shaikh, Ishita Yellapurkar, G. Pavale, M. Ramana","doi":"10.2298/jsc210428041b","DOIUrl":"https://doi.org/10.2298/jsc210428041b","url":null,"abstract":"A series of novel fluorinated 1,5-benzothiazepine derivatives were synthesized, characterized and evaluated for in vitro anticancer and antibacterial activity. The in vitro anticancer activity of the synthesized compounds 4(a-h) was evaluated against four human cancer cell lines namely lung (A549), breast (MCF-7), liver (HEPG2) and prostate (PC-3) cancer. Compounds 4c, 4d, 4g and 4h exhibited good activity with GI50 <10 ?g ml-1 against all four human cancer cell lines which was comparable to standard drug Adriamycin. Additionally, antibacterial activity of synthesized compounds was estimated using resazurin microtiter assay (REMA) and compared with standard drug Ampicillin. Among the synthesized compounds, 4c, 4d, 4g and 4h showed in good antibacterial activity and all the synthesized compounds were found to be more active towards gram negative than gram positive. These promising results obtained from in vitro anticancer and antibacterial activity, inferred that the synthesized compounds are capable of being anticancer as well as antibacterial agent.","PeriodicalId":17489,"journal":{"name":"Journal of The Serbian Chemical Society","volume":"321 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68507781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of some benzylidene thiosemicarbazide derivatives and evaluation of their cytotoxicity on U87, MCF-7, A549, 3T3 and HUVEC cell lines 一些苄基硫代氨基脲衍生物的合成及其对U87、MCF-7、A549、3T3和HUVEC细胞的细胞毒性评价

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc210630016e

Touba Eslaminejad, Yaghoub Pourshojaei, M. Naghizadeh, Hoda Eslami, Mohammad Daneshpajouh, A. Hassanzadeh

{"title":"Synthesis of some benzylidene thiosemicarbazide derivatives and evaluation of their cytotoxicity on U87, MCF-7, A549, 3T3 and HUVEC cell lines","authors":"Touba Eslaminejad, Yaghoub Pourshojaei, M. Naghizadeh, Hoda Eslami, Mohammad Daneshpajouh, A. Hassanzadeh","doi":"10.2298/jsc210630016e","DOIUrl":"https://doi.org/10.2298/jsc210630016e","url":null,"abstract":"Iron homeostasis is altered in tumours in response to a perturbation in the expression of iron-dependent proteins. Therefore, iron chelators make cancerous cells more vulnerable to iron deficiency. Compounds having thiosemicarbazide scaffold with the ability to metal complex formation have the potential to act as anticancer. A series of thiosemicarbazide derivatives were designed, synthesized successfully and their cytotoxicity was then tested on some cancerous as well as laboratory normal model systems by using colorimetric assay based on WST-1 reagent. According to the cytotoxicity results, some compounds showed high toxicity effect on both the cancerous and healthy cell lines. The results of toxicity assays on U87 and A549 cell lines showed the survivability less than 50% at all concentrations higher than 10 ppm for all the synthesized compounds. The MCF-7 cell line approximately exhibited the same behaviour and had survivability less than 60%. The 3T3 in compared with HUVEC cell line showed a completely different behaviour against the synthesized compounds and had survivability more than 50%. The selectivity index was also measured and based on the study results this could be concluded that the cytotoxicity profile of the synthesized compounds on 3T3 cell line shows a significant difference, indicating a good anticancer effect for these compounds.","PeriodicalId":17489,"journal":{"name":"Journal of The Serbian Chemical Society","volume":"1 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68508032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Green chemical principles based regioselective functionalization of 2,4,6-trichloropyrimidine-5-carbaldehyde: Application in the synthesis of new pyrimidines and pyrrolopyrimidine 基于2,4,6-三氯嘧啶-5-乙醛区域选择性功能化的绿色化学原理:在新嘧啶和吡咯嘧啶合成中的应用

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc210804063u

Allu Udayasri, Manchikanti Chandrasekhar, Brahmeswararao Naga, Ganesh Varanasi, D. Ramakrishna

引用次数: 3

Optimization of the slaughterhouse water treatment rate by a new Marinobacter carbonoclasticus SF and its biosurfactant 新型破碳海洋杆菌及其生物表面活性剂对屠宰场水处理率的优化

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc211029023m

Nadia Mihoubi, S. Ferhat, R. Alouaoui, A. Ibrir, M. Nedjhioui, A. Badis

{"title":"Optimization of the slaughterhouse water treatment rate by a new Marinobacter carbonoclasticus SF and its biosurfactant","authors":"Nadia Mihoubi, S. Ferhat, R. Alouaoui, A. Ibrir, M. Nedjhioui, A. Badis","doi":"10.2298/jsc211029023m","DOIUrl":"https://doi.org/10.2298/jsc211029023m","url":null,"abstract":"The aim of this study consists of the production of a bio-surfactant from a new bacterial strain, Marinobacter hydrocarbono clasticus SF (96.76 % simila-rity) isolated from soil contaminated by hydrocarbons in Hassi-Messaoud. (Southern Algeria) to treat liquid effluent from slaughterhouse water. The characteristics of organic matter biodegradation tests were discussed. Despite the high pollutant load and the unfavorable Physico-chemical composition of the effluent, the specific growth rate of the isolated strain after 10 days of incubation in the range of 0-30 g L-1 of NaCl was at neutral pH 7.4 and temperature of 45 ?C. The best bio-surfactant production yield was obtained after 72 h of incubation and under the optimal production conditions such as diesel as carbon source, ammonium chloride as nitrogen source, and a C/N ration of 5. The bio-surfactant produced is of glycolipid type with a low critical micellar concentration (CMC), good emulsifying power, and chemical and functional stability. Significant pollutant removal efficiency was obtained using the bacterial strain (up to 82 %) and the bio-surfactant (up to 96 %). Several anions, such as nitrates, phosphates, ammonium, and suspended solids, were measured.","PeriodicalId":17489,"journal":{"name":"Journal of The Serbian Chemical Society","volume":"1 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68510506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The influence of different enzymatic preparations and skin contact time on aromatic profile of wines produced from autochthonous grape varieties Krstac and Zizak 不同酶制剂和皮肤接触时间对本地葡萄品种Krstac和Zizak葡萄酒芳香特征的影响

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc220311056m

Valerija Madzgalj, A. Petrovic, U. Čakar, V. Maras, Ivana Sofrenić, V. Tešević

{"title":"The influence of different enzymatic preparations and skin contact time on aromatic profile of wines produced from autochthonous grape varieties Krstac and Zizak","authors":"Valerija Madzgalj, A. Petrovic, U. Čakar, V. Maras, Ivana Sofrenić, V. Tešević","doi":"10.2298/jsc220311056m","DOIUrl":"https://doi.org/10.2298/jsc220311056m","url":null,"abstract":"This study aimed to show aromatic profile of wines produced from two autochthonous grape cultivars Krstac (K) and Zizak (Z). During the wine production two enzymatic preparations (EP) (Lallzyme cuvee blanc (CB) and Lallzyme enzymatic preparation ? (EB)) and different time of skin contact (4 and 8 h) were applied. Aromatic compounds were detected by GC/FID-MS analysis. Significantly higher content of total detected aromatic compounds compared to appropriate controls (168.54 and 161.72 mg L-1) was observed for K EB4h (176.33 mg L-1) and Z CB4h (177.29 mg L-1) wines. Skin contact and usage of EP mostly increased content of 2-phenylethyl and isoamyl alcohols. Wines from both varieties showed higher content of hexanoic and octanoic acids compared to control. It is interesting to emphasize that content of esters which are responsible for fruity aroma of wine which is important for pleasant taste (isoamyl acetate - banana, ethyl hexanoate - ripe banana, 2-phenylethyl acetate - powerful fruity rose like) were increased in all samples compared to controls. The highest grades after sensory evaluation were obtained for K EB 8h (18.0 out of 20.0) and Z CB 8h (18.2 out of 20.0).","PeriodicalId":17489,"journal":{"name":"Journal of The Serbian Chemical Society","volume":"1 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68513889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Ammonia removal by natural modified clinoptilolite 天然改性斜沸石脱氨研究

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc211110051g

Aytaç Günal, Burcu Erdoğan

引用次数: 0

Synthesis of activated carbons from water hyacinth biomass and its application as adsorbents in water pollution control 水葫芦生物质活性炭的合成及其吸附剂在水污染控制中的应用

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc212121006m

Ahmad Mohammaad, M. Kijevčanin

{"title":"Synthesis of activated carbons from water hyacinth biomass and its application as adsorbents in water pollution control","authors":"Ahmad Mohammaad, M. Kijevčanin","doi":"10.2298/jsc212121006m","DOIUrl":"https://doi.org/10.2298/jsc212121006m","url":null,"abstract":"The water hyacinth biomass was used for the synthesis of activated carbons in process of chemical activation with ZnCl2, followed by controlled pyrolysis. The applied impregnation weight ratios ZnCl2 and dry hyacinth biomass were in the range of 0.5 - 3.5. The carbonization was conducted at four different temperatures (T= 400-700?C) under an inert atmosphere. The highest yield of activated carbon was obtained for the impregnation ratio of 0.5 and carbonization temperature of 400?C. The samples were characterized using elemental analysis, adsorption-desorption isotherms of nitrogen and SEM analysis. The activated carbon obtained with an impregnation ratio 2.0 and carbonization temperature of 500?C (2.0AC500) showed the highest values of specific surface area and total pore volume of 1317 m2 g-1 and 0.697 cm3 g-1, respectively. The adsorption of glyphosate, pesticide with a strong negative environmental impact, was fast process, with equilibrium time of 120 min. The adsorption isotherms were fitted with Langmuir and Freundlich model. The Langmuir adsorption capacity of qmax=240.8 mg g-1 for 2.0AC500 classified the selected adsorbent as a very efficient one. The tested adsorption process followed the kinetics of the pseudo-second-order model.","PeriodicalId":17489,"journal":{"name":"Journal of The Serbian Chemical Society","volume":"30 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68512015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Leaching of heavy metals from wood biomass ash, before and after binding in cement composite 水泥复合材料粘结前后木材生物质灰中重金属的浸出

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc220217054d

D. Drljaca, Ljiljana Vukic, Dajana Dragic, A. Borkovic, T. Botic, P. Dugic, Saša Papuga, Marko Solic, S. Maletić, P. Gvero, Jelena Savkovic

{"title":"Leaching of heavy metals from wood biomass ash, before and after binding in cement composite","authors":"D. Drljaca, Ljiljana Vukic, Dajana Dragic, A. Borkovic, T. Botic, P. Dugic, Saša Papuga, Marko Solic, S. Maletić, P. Gvero, Jelena Savkovic","doi":"10.2298/jsc220217054d","DOIUrl":"https://doi.org/10.2298/jsc220217054d","url":null,"abstract":"Wood ash is a complex mixture of inorganic and organic compounds. It is heterogeneous in composition, which can vary considerably. Ash is mainly disposed of in landfills, which poses a risk for air, soil and groundwater contamination by trace elements. In order for wood biomass ash to be used as a secondary raw material, it is necessary to perform leaching tests, to determine which microelements it contains, and which of them could be released into the environment during the ash disposal. Sequential extraction showed that in the exchangeable and carbonate fraction, the most volatile metals As, Cd, Zn and Pb are released the most from the ash of deciduous trees, while the leaching of ash from coniferous trees is significantly lower. The evaluation of risk assessment code (RAC) for the tested biomass ash samples, indicates that Pb is a high-risk leaching element due to its condensation on the ash particles. By performing TCLP (Toxicity Characteristic Leaching Procedure) and SPLP (Synthetic Precipitation Leaching Procedure) tests, it was established that the released concentrations of tested metals are below the maximum allowable concentration, given by the Regulation. The leaching tests of composites, prepared from wood ash in combination with cement, indicate that the leaching of ash is reduced to a minimum, and that all heavy metals are bound in a cement matrix, which indicates the possibility of using wood ash for construction purposes.","PeriodicalId":17489,"journal":{"name":"Journal of The Serbian Chemical Society","volume":"1 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68513302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Divergent synthesis and antitumour activity of novel conformationally constrained (−)-muricatacin analogues 新型构象约束(−)-穆里卡星类似物的发散合成和抗肿瘤活性

IF 1 4区化学

Journal of The Serbian Chemical Society Pub Date : 2022-01-01 DOI: 10.2298/jsc220613069s

Sladjana Stanisavljevic, Bojana Sreco-Zelenovic, Mirjana Popsavin, M. Rodić, V. Popsavin, V. Kojić

引用次数: 0