{"title":"Adjustment of surface condition for self-generation of droplet array using oil-water replacement","authors":"H. Yasuga, N. Miki","doi":"10.1109/TRANSDUCERS.2017.7994507","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994507","url":null,"abstract":"This paper demonstrates a method to self-generate a two-dimensional (2D) array of nanoliter-scale droplets. 2D droplet arrays are powerful tools for high throughput and low-cost processes in the field of biology or medicine. We recently developed a self-generation method of droplet array without precise liquid control such as precise pipetting or pumping. The next challenge of the self-generation is the further miniaturization of generated droplets. Here, we addressed it by applying a photoresist off-stoichiometry thiol-ene (OSTE), of which surface energy can be tuned by polymer chain grafting. We experimentally found the surface conditions to self-generate an array of nanoliter-scale droplets.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129674974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Tao, H. Chang, J. Wu, L. H. Tang, A. Kottapalli, L. Hu, S. Lye, J. Miao
{"title":"Enhanced performance of electrostatic energy harvester with integrated opposite-charged electrets","authors":"K. Tao, H. Chang, J. Wu, L. H. Tang, A. Kottapalli, L. Hu, S. Lye, J. Miao","doi":"10.1109/TRANSDUCERS.2017.7994428","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994428","url":null,"abstract":"This paper presents a novel electrostatic vibration energy harvester with two opposite-charged-electret design for enhanced output performance. The device consists mainly of three parallel silicon plates. The middle plate of spring-mass resonant system is double-side patterned with electrodes. The negatively and positively charged electret plates are located on the bottom and top positions, respectively. Therefore, when the movable mass reaches its highest and lowest positions, maximum charge can be induced at both extremes. These are superior to the traditional two-plate configuration where maximum charge can only be created at lowest position of seismic mass. As a proof of concept, an electret-based energy harvester (e-VEH) has been designed and fabricated. Experimental results demonstrate the output voltage increases by 18.6% and 80.9% compared to the bottom electret alone and top alone configurations, respectively. This research provides a simple and effective method for improving the performance of e-VEHs.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124923683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differentiation of neural stem cells regulated by three-dimensional tissue shape","authors":"Yuki Matsushiro, M. Kato‐Negishi, H. Onoe","doi":"10.1109/TRANSDUCERS.2017.7994044","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994044","url":null,"abstract":"This paper describes the effect of three-dimensional (3D) tissue shape on differentiation ratio of neurons. We cultured mouse neural stem cells (mNSCs) in the closed agarose microchamber sealed with an agarose sheet. We succeeded in fabricating mNSC tissues of various 3D shapes in the closed agarose microchamber and induced differentiation of the lane-shaped mNSC tissues to neurons and glial cells. We confirmed that tissues of thin width and thickness have higher differentiation ratio of neurons than that of spherical-shaped tissue, by changing the width and thickness of the lane shaped tissues.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128148620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhenzhen Xie, M. V. R. Raju, Benjamin S. Brown, Andrew C. Stewart, M. Nantz, Xiao-an Fu
{"title":"Electronic nose for detection of toxic volatile organic compounds in air","authors":"Zhenzhen Xie, M. V. R. Raju, Benjamin S. Brown, Andrew C. Stewart, M. Nantz, Xiao-an Fu","doi":"10.1109/TRANSDUCERS.2017.7994326","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994326","url":null,"abstract":"We demonstrate a general approach using novel thiols to functionalize gold nanoparticles for fabricating gas sensors to detect toxic volatile organic compounds (VOCs) in air. Poor selectivity and low sensitivity are common challenges for chemiresistor-based gas sensors. Gold nanoparticle-based gas sensors have the advantage of accommodating thiols for surface modification. The designed thiols with a molecular recognition motif for interaction with target analytes dramatically increase both selectivity and sensitivity of the sensors. The sensors showed a linear response relationship in a broad vapor concentration range from 0.1 ppb to 1000 ppm for various VOCs. A sensor array of the thiol functionalized gold nanoparticles enables analysis of target VOCs.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132104848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masahide Gotanda, K. Kamiya, T. Osaki, S. Fujii, N. Misawa, N. Miki, S. Takeuchi
{"title":"Sequential production of various types of asymmetric lipid vesicles using pulse jet flow","authors":"Masahide Gotanda, K. Kamiya, T. Osaki, S. Fujii, N. Misawa, N. Miki, S. Takeuchi","doi":"10.1109/TRANSDUCERS.2017.7994113","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994113","url":null,"abstract":"This paper describes a method of sequential formation of asymmetric lipid vesicles, which applies pulse jet flow to an asymmetric planar lipid bilayer with multiple lipid components formed by Droplet Split-and-Contact Method. In our previous work, we generated asymmetric lipid vesicles by deforming an asymmetric planar lipid bilayer using a pulsed jet flow. However, it was difficult to create various types or large amounts of the asymmetric lipid vesicles in a single double-well device. In this study, asymmetric planar lipid bilayers with multiple lipid components were formed by contacting various types of lipid monolayers using movable wells on a revolving table. We successfully produced two types of the asymmetric lipid vesicles containing red or green fluorescent lipids on the outer leaflet with a single device in a high-throughput manner using the proposed method. The asymmetricity of the generated vesicles was evaluated by the distribution of the fluorescence intensities. The proposed device will be applicable for generating artificial cell models with multiple asymmetric lipid components.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124226677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ballistic energy conversion","authors":"J. Eijkel, A. van den Berg, Yanbo Xie","doi":"10.1109/TRANSDUCERS.2017.7994000","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994000","url":null,"abstract":"Ballistic energy conversion is the direct conversion of kinetic energy into electrical energy. Aqueous droplet-based platforms are eminently suitable for this method, as droplets can be conveniently supplied with both kinetic energy and electrical charge. Starting with the 19th century gravity-driven Kelvin thunderstorm and the electrostatic generators of Melcher and Zahn from the 1960s, we describe the recent development of ballistic energy conversion both in experiment and theory. With this method experimental efficiencies of 48% have been reached at 20 kV operating voltage with an extremely simple setup. Theory predicts maximal efficiencies of more than 90%, operation at <100 Volt. Downscaling also promises to remove one of the largest disadvantages of electrostatic generators, namely the low power density: power densities of 1–1000 kW/m2 are predicted.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127655274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiple structural color hydrogel array integrated with microfluidic chip for biochemical sensor","authors":"Kenta Niibe, H. Onoe","doi":"10.1109/TRANSDUCERS.2017.7994027","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994027","url":null,"abstract":"This paper describes multiple structural color hydrogel array integrated with a two-layered microfluidic chip. The microfluidic chip can sense multiple physical/chemical targets (ex. concentration of chemicals and temperature) at the same time simply by eye-visible color changes of the arrayed stimuli-responsive structural color hydrogels in the top chambers. Sample solution was introduced in the bottom channel and react to the arrayed hydrogel via sandwiched porous membrane. We evaluated our device by measuring ethanol/water concentration and temperature, and confirmed the visible color changes of our sensor without any external equipment. We believe that our sensing device could be applied to a biochemical sensor or microanalytical chip for environmental monitoring sensor and wearable healthcare devices.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126934514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Broadband frequency viscositymeasurement using low TCF shear mode resonators consisting of C-axis tilted scaln thin film on thick at-cut quartz plate","authors":"Y. Yamakawa, K. Sano, R. Karasawa, T. Yanagitani","doi":"10.1109/TRANSDUCERS.2017.7994497","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994497","url":null,"abstract":"In order to study relaxation characteristics of acoustic velocity and viscoelasticity of the liquid, a wide frequency sweep in the range of MHz to GHz is desired. Thickness shear acoustic mode (TSM) viscosity sensors such as QCM or FBAR can only operate at the MHz range or the GHz range, respectively. In this study, therefore, we report a new type HBAR (High-overtone Bulk Acoustic Resonator) sensor which makes it possible to operate in a wide frequency range. The HBAR consists of the c-axis tilted ScAlN film grown on a zero TCF AT-cut quartz crystal plate. Frequency shifts were measured for various concentration of glycerine solutions. As a result, the tendency of resonant frequency decreasing caused by liquid viscosity increasing is observed in both theoretical and experimental data.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115330065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yumiko Tanaka, N. Suzuki, Kazuyo Mora, J. Mizuno, S. Shoji, S. Uemura, Y. Shirasaki
{"title":"Widefield real-time single-cell secretion imaging with optical waveguide technique","authors":"Yumiko Tanaka, N. Suzuki, Kazuyo Mora, J. Mizuno, S. Shoji, S. Uemura, Y. Shirasaki","doi":"10.1109/TRANSDUCERS.2017.7994363","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994363","url":null,"abstract":"We report the novel methodology which enables us to analyze single-cell secretion dynamics on the widefield total internal reflection fluorescence imaging with high spatial and temporal resolution using the optical waveguide technique. The practical system was achieved after some sensitivity improvements in an optical waveguide imaging, which has succeeded in detecting very weak fluorescence signals reflecting single-cell secretion dynamics in spite of using a low magnification objective lens. Our methodology is more advantageous than other traditional microscopic technologies in real-time imaging of cell-to-cell communication through humoral factor secretion among actively migrating cells, like immune cells do in vivo.","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122493228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An ultrasensitive mercury sensor based on self-assembled graphene and gold nanoparticles on shrink polymer","authors":"Zonghao Wu, G. Jing, T. Cui","doi":"10.1109/TRANSDUCERS.2017.7994031","DOIUrl":"https://doi.org/10.1109/TRANSDUCERS.2017.7994031","url":null,"abstract":"Ultrasensitive trace mercury (II) micro sensor fabricated by mixed gold nanoparticle (Au NPs) and graphene suspension solution, and layer-by-layer self-assembled (LBL SA) on a shrink polymer based micro gold electrode is reported for the first time. Owing to the unique wrinkle surface structure and superior properties of modification film, performance of the LBL SA Graphene-Au NPs shrink sensor has enhanced greatly in determination of Hg (II) using anodic stripping voltammetry (ASV): compared with a shrink gold electrode without surface modification, the sensitivity is improved for about 3.7 times from 0.197 μA/ppb to 0.721 μA/ppb; compared with a same-sized sensor without surface modification nor shrink, the sensitivity is improved for over 50 times. This sensor's detection limit of Hg (II) achieved 0.931 ppb with a sensitivity of 0.721 μΑ/ppb. This simple but highly sensitive sensor can be widely used in applications of on-line environmental monitoring of Hg (II).","PeriodicalId":174774,"journal":{"name":"2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126574720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}