Journal of the Turkish Chemical Society, Section A: Chemistry最新文献_第9页

Voltammetric Analysis of Cephalexin and Cefazoline in Pharmaceutical Formulation and Biological Samples 制剂和生物样品中头孢氨苄和头孢唑啉的伏安分析

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.469028

S. Özkorucuklu, Besnik Uka, Gizem Yıldırım Baştemur

引用次数: 9

Morphological and rheological study of the epoxy polymer and their nanocomposite (NGTHTPTBAE/MDA/TSP) crosslinked by methylene dianiline and formulated by trisodium phosphate 亚甲基二苯胺交联磷酸三钠制备环氧聚合物及其纳米复合材料（NGTHTPTBAE/MDA/TSP）的形态和流变学研究

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.477191

R. Hsissou, M. Berradi, M. E. Bouchti, A. Harfi

引用次数: 7

Simultaneous Deposition of Poly(o-anisidine) and Noble Ag Particles on Wool Fabric and The Evaluation of Its Performance as Catalyst in Dye Reduction 聚(o-茴香胺)和银粒子在羊毛织物上的同时沉积及其作为染料还原催化剂的性能评价

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.512360

M. K. Erdoğan, M. Karakışla

引用次数: 3

Inhibition of Carbonic Anhydrase, Acetylcholinesterase and Butyrylcholinesterase by BisPMB, A Synthetic Analogue of Ajoene Ajoene的合成类似物BisPMB对碳酸酐酶、乙酰胆碱酯酶和丁酰胆碱酯酶的抑制作用

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.484444

N. Stellenboom

引用次数: 2

Solution Combustion Synthesis of Iron Oxyborate (Fe3BO6) 溶液燃烧合成氧硼酸铁（Fe3BO6）

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.500355

D. Ozer, O. Icten

引用次数: 4

Concentration of heavy metals in Mirusha and Stanishor rivers of Gjilan municipality and their impact on pollution of the Morava river, Kosovo Gjilan市Mirusha河和Stanishor河的重金属浓度及其对科索沃Morava河污染的影响

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.489098

V. Beluli, Ismet Mulliqi

{"title":"Concentration of heavy metals in Mirusha and Stanishor rivers of Gjilan municipality and their impact on pollution of the Morava river, Kosovo","authors":"V. Beluli, Ismet Mulliqi","doi":"10.18596/JOTCSA.489098","DOIUrl":"https://doi.org/10.18596/JOTCSA.489098","url":null,"abstract":"Pollution with the heavy metals of Kosovo's rivers has been and continues to be a serious concern not only for the population, but also for responsible institutions that deal with environmental protection in our country. Based on this fact and our doubts regarding the quality of the river waters of the Municipality of Gjilan, we were motivated to conduct a study of the quality of the Mirusha, Stanishor and Morava river waters. During our research, we have set eight monitoring points for determining the exact level of concentration of heavy metals in the river waters quoted above. The heavy metals analyzed in this study were: Pb, Hg, Mn, Cu, Fe, Ni, Cr, Cd, Zn and Ba. The analytical technique used to determine the concentration of heavy metals was ICP-OES. The obtained results show that Fe, Mn and Ba exceed the allowed level at several monitoring points of the Mirusha and Stanishor rivers and appears in the degree of pollution with these metals of Morava river waters. The presence of heavy metals in the waters of these rivers negatively affects habitat waters and indirectly human health. Therefore, the identification and then suggestions regarding elimination of polluting sources are the subject of this study.","PeriodicalId":17402,"journal":{"name":"Journal of the Turkish Chemical Society, Section A: Chemistry","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41501250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis, Characterization, and Carbonic Anhydrase Inhibitory Properties of Silver(I) Complexes of Benzimidazole Derivatives 苯并咪唑衍生物银配合物的合成、表征及碳酸酐酶抑制性能

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-05-21 DOI: 10.18596/JOTCSA.546960

Mert Ogun Karataş, Adem Ergün

引用次数: 1

Phytochemical Evaluation of Morus alba Seeds and Cold Pressed Oil 桑树种子和冷榨油的植物化学评价

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-05-15 DOI: 10.18596/JOTCSA.470279

Zeliha Ustun Argon, N. Ilhan, A. Gökyer, S. Öztürk, Beril Koparal

{"title":"Phytochemical Evaluation of Morus alba Seeds and Cold Pressed Oil","authors":"Zeliha Ustun Argon, N. Ilhan, A. Gökyer, S. Öztürk, Beril Koparal","doi":"10.18596/JOTCSA.470279","DOIUrl":"https://doi.org/10.18596/JOTCSA.470279","url":null,"abstract":"This study has focused on Morus alba, which is grown in Turkey mostly for fruit production. M. alba seeds’ analysis results showed that oil, protein, ash, ash insoluble in hydrochloric acid, total carbohydrate were 21%, 21.58±0.13g, 3.99±0.13g, 0.9±0.00g, 54.76±2.42 g/100g respectively, main minerals were calcium, phosphorus and potassium. Dominated fatty acids were linoleic acid (80.56±0.22), palmitic acid (7.96±0.06), oleic acid (7.11±0.05). The primary volatiles were l-limonene, 2,2-dimethyldecane, hexanal. Sterol components were found as beta-sitosterol>delta-5-avenasterol>campesterol>cholestanol with 5501.49±44.26 mg/kg total sterols. Tocopherols were δ-tocopherol, γ-tocopherol, β-tocopherol, α-tocopherol, total phenolic content, the radical scavenging activity were 257.67 ± 4.51, 18.23 ± 0.11, 6.71 ± 0.13, 3.23 ± 0.06 mg/kg, 137.1±0.36 mgGAE/100goil, 19.9±0.46% respectively. Other physicochemical properties were free fatty acid (1.55±0.89% oleic acid), peroxide value (3.23±0.55 meqO 2 /kg oil), p-anisidine value (1.18±0.55) and refractive index (40 0 C) (1.4687±0.00). As a result, M. alba seeds and oil with its fatty acid, tocopherol, sterol and mineral composition can be used as nutritional supplements.","PeriodicalId":17402,"journal":{"name":"Journal of the Turkish Chemical Society, Section A: Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44970727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Discovery of New DNA Topoisomerase II Inhibitors using Structure Based Virtual Screening Method 基于结构的虚拟筛选方法发现新的DNA拓扑异构酶II抑制剂

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-05-15 DOI: 10.18596/JOTCSA.466457

T. Ertan-Bolelli, K. Bolelli

{"title":"Discovery of New DNA Topoisomerase II Inhibitors using Structure Based Virtual Screening Method","authors":"T. Ertan-Bolelli, K. Bolelli","doi":"10.18596/JOTCSA.466457","DOIUrl":"https://doi.org/10.18596/JOTCSA.466457","url":null,"abstract":"DNA topoisomerases are proved therapeutic targets of anticancer and antibacterial drugs. Structures of topoisomerase–DNA and inhibitor ternary complexes have revealed the exact binding sites and mechanisms of topoisomerase poisons. There are two isoforms of Human Topoisomerase II; α and β. Both of them perform similar functions and their levels differ depending on the replicative activity and type of tissue. Topo IIα is preferentially expressed in proliferating cells. Thus selective Topo IIα inhibitors have been of particular interest in cancer therapy, as they may represent a more targeted approach to highly proliferative cells. In this study, we use structure based virtual screening method with molecules which are commercially available in the ZINC database. Docking studies were performed by Glide module available in Schrodinger software, Ligand filtration was also done to obtain an efficient collection of hit molecules by employing Lipinski “rule of five” and pharmacokinetic properties of the compounds were tested using Qikprop module. From approximately ten thousand compounds from Zinc database it was possible to select 4 top chemical structures with good inhibiting profile for topo II, with suitable ADME/Tox properties, thus comp. 1-4 could be the promising inhibitors of human topo IIα enzyme.","PeriodicalId":17402,"journal":{"name":"Journal of the Turkish Chemical Society, Section A: Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49567362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Doping Agent Naphazoline Hydrochloride: Development of Simple and Fast Voltammetric Method for Its Determination in Human Serum 掺杂剂盐酸萘唑啉:建立简单快速测定人血清中萘唑啉的伏安法

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-05-15 DOI: 10.18596/JOTCSA.450793

Tuğçe Çetinkol, F. Öztürk, P. Erden

引用次数: 1