Journal of the Turkish Chemical Society, Section A: Chemistry最新文献_第8页

Antioxidant, acetylcholinesterase and butyrylcholinesterase inhibition profiles of histamine Schiff bases 组胺席夫碱对抗氧化剂、乙酰胆碱酯酶和丁酰胆碱酯酶的抑制作用

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.521291

Suleyman Akocak, Nabih Lolak, Muhammed Tuneğ, M. Boğa

引用次数: 13

Molecular Docking Study of Four Chromene Derivatives as Novel HIV-1 Integrase Inhibitors 四种铬衍生物作为新型HIV-1整合酶抑制剂的分子对接研究

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.478772

N. Arslan

引用次数: 3

A Novel ZnO Nanoparticle as Drug Nanocarrier in Therapeutic applications: Kinetic Models and Error Analysis 一种新型ZnO纳米颗粒作为药物纳米载体在治疗中的应用:动力学模型和误差分析

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.405505

S. Karakuş

{"title":"A Novel ZnO Nanoparticle as Drug Nanocarrier in Therapeutic applications: Kinetic Models and Error Analysis","authors":"S. Karakuş","doi":"10.18596/JOTCSA.405505","DOIUrl":"https://doi.org/10.18596/JOTCSA.405505","url":null,"abstract":"Nanotechnology provides promising possibilities for several biomedical and pharmaceutical applications in the medicine industry. Nanostructures play a major role in the recent strategies of technology suitable for novel drug applications. In this work, clindamycin phosphate (CliP) (topical anti-inflammatory drug), xanthan gum (XaG) (biopolymer) and ZnO (zinc oxide) (nanoparticle) nanostructures were synthesised using the sonochemical technique at room temperature. The characterization of the clindamycin phosphate- xanthan gum/ZnO (CliP-XaG/ZnO) nanostructure has been carried out by Fourier transform infrared (FTIR) and X-ray diffraction (XRD). The spectroscopic experiments elucidated in vitro the mechanism of drug delivery system at different pH media (1.2 and 7.4). In this study, the concentration of drug in the solution was analyzed by UV–vis spectroscopy method and several kinetic models and error analysis were calculated to prove a connection with results. The Higuchi model had the best correlation parameters. The percentage of swelling ratio (%) reached up 105% in XaG (pH 1.2) and 190% in XaG/ZnO (pH 1.2) And the swelling ratio (%) reached up 530% within in XaG (pH 7.4) and 655% within in XaG/ZnO (pH 7.4). The results show that the capacity of XaG / ZnO can be preferred as a novel topical anti-inflammatory drug carrier.","PeriodicalId":17402,"journal":{"name":"Journal of the Turkish Chemical Society, Section A: Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42523950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Study on the Synthesis and Characterization of Antibacterial Polystyrenes 抗菌聚苯乙烯的合成与表征研究

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.547471

G. Acik

引用次数: 4

Essential Oil Composition Of Two Scutellaria species from Tokat, Turkey 土耳其托卡特两种黄芩的精油成分

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.466906

M. Kürkçüoǧlu, Gülsüm Yıldız, Y. Köse

引用次数: 6

The Comparison of the Quality Properties of Some Commercial Cold Pressed Seed Oils 几种商品冷榨种子油品质特性的比较

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.496458

Hazal Özyurt

{"title":"The Comparison of the Quality Properties of Some Commercial Cold Pressed Seed Oils","authors":"Hazal Özyurt","doi":"10.18596/JOTCSA.496458","DOIUrl":"https://doi.org/10.18596/JOTCSA.496458","url":null,"abstract":"In this study, it is aimed to define the properties which determine their effects on the quality and health of five different kinds of seed oils produced by the cold pressed extraction method. The cold pressed seed oils known as coffee bean, pomegranate, cherry, apricot, and fig kernels which are produced in the domestic market of Turkey were bought to determine the quality characteristics such as peroxide values, free fatty acidity, and UV-specific absorption values, total phenolic compounds and antioxidant activity of these seed oils. When the peroxide values were examined, the highest peroxide value was found in coffee bean oil and the lowest peroxide value was found in pomegranate seed oil. When the free fatty acidity is considered, the number of free fatty acids is ranked from the highest to the lowest as coffee bean oil, fig kernel oil, sour cherry seed oil, pomegranate seed oil, and apricot kernel oil. The K 232 value was found to be the highest in coffee bean oil while it was the lowest in apricot kernel oil. K 270 values were the highest in pomegranate seed and the lowest in the apricot kernel. As seen in the results of the total phenolic compound analysis performed to recognize the effects on health, this value was highest in coffee bean oil, followed by apricot kernel oil, fig kernel oil, pomegranate seed oil, and sour cherry seed oil. When the results antioxidant activity analysis were examined, the antioxidant activity of apricot kernel oil was found to be the lowest, while this value of fig kernel oil was found to be the highest. According to the analysis of variance, these differences were statistically found to be significant. In addition, these values were compared with the studies in the literature and evaluated according to the legal limits. These products sold on the grounds that they have beneficial effects on health in the market should be implemented with more stringent procedures to be audited by public institutions and legal regulations should be supported by further scientific studies.","PeriodicalId":17402,"journal":{"name":"Journal of the Turkish Chemical Society, Section A: Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45668838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

METAL-ORGANIC FRAMEWORKS (MOFs) DERIVED FROM CARBOXYLATE LIGAND AS POTENTIAL MATERIALS FOR REMEDIATION OF Cu (II) AND Pb (II) FROM AQUEOUS SOLUTION 摘要由羧酸配体衍生的金属有机骨架(MOFs)作为修复水溶液中Cu (II)和Pb (II)的潜在材料

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.454010

H. Okoro, Oluwaseyi Ayika, A. Tella, J. Ngila

引用次数: 2

Synthesis, molecular structure, Hirshfeld surface analysis, spectroscopic and computational studies (DFT) of 6,6'-((1E,1'E)-(1,2-phenylenebis(azanylylidene))bis(methanylylidene))bis(2-(tert-butyl)-4-methylphenol) 6,6'-((1E, 1E)-(1,2-苯基双(azanylylidene)) -(2-(叔丁基)-4-甲基苯酚)的合成、分子结构、Hirshfeld表面分析、光谱和计算研究(DFT)

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.483143

P. Şen, S. Kansız, N. Dege

{"title":"Synthesis, molecular structure, Hirshfeld surface analysis, spectroscopic and computational studies (DFT) of 6,6'-((1E,1'E)-(1,2-phenylenebis(azanylylidene))bis(methanylylidene))bis(2-(tert-butyl)-4-methylphenol)","authors":"P. Şen, S. Kansız, N. Dege","doi":"10.18596/JOTCSA.483143","DOIUrl":"https://doi.org/10.18596/JOTCSA.483143","url":null,"abstract":"Schiff bases have been used in biological processes and as chelating agents for several decades. This work presents the synthesis and characterization of compound, N,N’-Bis(3-tert-Butyl-5-methylsalicylidene)-1,2-diamino phenylene as the Schiff base derivative with the reaction of an aromatic aldehyde derivative and o-phenylenediamine. The spectroscopic properties of the compound were examined by FT-IR, 1 H NMR, 13 C NMR, MS and elemental analyses. The molecular structure of the compound was also confirmed using X-ray single-crystal data. And also theoretical calculations were obtained by using Density Functional Theory (DFT) methods. T he structural parameters were calculated by using DFT/B3LYP/6-31G(d,p) basis set in ground state. Molecular Electrostatic Potential (MEP) map and the frontier molecular orbitals (HOMO-LUMO) of the compound were created by using the optimized structures. The results of theoretical study using the DFT method at the B3LYP/6–31G(d,p) level are in good agreement with the experimental data . Hirshfeld surface analyses and two dimensional fingerprint plots were used to analyse the intermolecular interactions present in the crystal, indicating that the most important contributions for the crystal packing are from H ∙∙∙ H (71.2%), H ∙∙∙ C/C ∙∙∙ H (18.7%), C ∙∙∙ C (4.8%) and H ∙∙∙ N/N ∙∙∙ H (2.7%) interactions.","PeriodicalId":17402,"journal":{"name":"Journal of the Turkish Chemical Society, Section A: Chemistry","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44691700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Voltammetric Analysis of Cephalexin and Cefazoline in Pharmaceutical Formulation and Biological Samples 制剂和生物样品中头孢氨苄和头孢唑啉的伏安分析

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.469028

S. Özkorucuklu, Besnik Uka, Gizem Yıldırım Baştemur

引用次数: 9

Morphological and rheological study of the epoxy polymer and their nanocomposite (NGTHTPTBAE/MDA/TSP) crosslinked by methylene dianiline and formulated by trisodium phosphate 亚甲基二苯胺交联磷酸三钠制备环氧聚合物及其纳米复合材料（NGTHTPTBAE/MDA/TSP）的形态和流变学研究

Journal of the Turkish Chemical Society, Section A: Chemistry Pub Date : 2019-06-15 DOI: 10.18596/JOTCSA.477191

R. Hsissou, M. Berradi, M. E. Bouchti, A. Harfi

引用次数: 7