Journal of tissue viability最新文献

{"title":"Modification and validation of the Bluebelle Wound Healing Questionnaire (WHQ) for assessing surgical site infection in wounds healing by secondary intention","authors":"Rhiannon Macefield ,&nbsp;Laura Mandefield ,&nbsp;Jane M. Blazeby ,&nbsp;Caroline Fairhurst ,&nbsp;Kalpita Baird ,&nbsp;Catherine Arundel ,&nbsp;Ian Chetter ,&nbsp;Belen Corbacho Martin ,&nbsp;Catherine Hewitt ,&nbsp;Athanasios Gkekas ,&nbsp;Andrew Mott ,&nbsp;Dr Pedro Saramago Goncalves ,&nbsp;Samantha Swan ,&nbsp;David Torgerson ,&nbsp;Jacqueline Wilkinson ,&nbsp;Sabeen Zahra ,&nbsp;Stephen Dixon ,&nbsp;Josie Hatfield ,&nbsp;Angela Oswald ,&nbsp;Jo Dumville ,&nbsp;E. Packer","doi":"10.1016/j.jtv.2025.100889","DOIUrl":"10.1016/j.jtv.2025.100889","url":null,"abstract":"<div><h3>Background</h3><div>Surgical wounds healing by secondary intention are common. Healing is often complicated by surgical site infection (SSI). SSI assessment is important to guide treatment but existing methods generally require in-person assessment, making them resource intensive. A validated patient-reported SSI outcome measure may be useful to overcome this limitation.</div></div><div><h3>Aim</h3><div>To modify and validate the Bluebelle Wound Healing Questionnaire (WHQ) for wounds healing by secondary intention.</div></div><div><h3>Methods</h3><div>The 18-item Bluebelle WHQ developed for wounds healing by primary intention was modified to make it applicable to secondary healing wounds. Testing was performed as part of the SWHSI-2 randomised trial assessing negative pressure wound dressings versus standard care. Participants completed the WHQ at five timepoints; in-person (baseline, post-healing) and by post (3, 6, 12 months). A reference SSI assessment was performed by a research nurse at the time of wound healing. Acceptability and criterion validity (ability of the Bluebelle WHQ to discriminate between SSI/no SSI) were explored by examining questionnaire return rates, levels of missing data and total score sensitivity/specificity values (receiver operating characteristic curve (ROC)).</div></div><div><h3>Results</h3><div>Baseline in-person questionnaire return rates were highest (672/686; 98 %), with postal return rates of 428/615 (68.5 %), 274/416 (65.9 %) and 186/296 (62.8 %) at follow up points. Overall, low levels of item-missing data were observed with few problems completing the questionnaire reported. Ability to discriminate between SSI/no SSI was good (Area under ROC = 0.796).</div></div><div><h3>Conclusion</h3><div>The modified Bluebelle WHQ is a valuable tool for post-discharge assessment of wounds healing by secondary intention. It is recommended for use in research and clinical practice.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100889"},"PeriodicalIF":2.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143936068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new conceptual model for how pressure ulcer risk is negotiated and adherence to preventative advice in the community setting","authors":"Lisa Ledger ,&nbsp;Jo Hope ,&nbsp;Lisette Schoonhoven ,&nbsp;Peter R. Worsley","doi":"10.1016/j.jtv.2025.100890","DOIUrl":"10.1016/j.jtv.2025.100890","url":null,"abstract":"<div><h3>Aim(s)</h3><div>To identify potential factors affecting patient adherence to preventative advice and to explore how pressure ulcer risk is negotiated between nurse and patient in the community setting.</div></div><div><h3>Design</h3><div>A qualitative research design using a pragmatist approach.</div></div><div><h3>Methods</h3><div>Observation of interactions between nurse and patient, evaluation of documentation, and semi-structured interviews with 15 community patients following the nursing interaction. Data was analysed using the principles of Thematic Analysis.</div></div><div><h3>Results</h3><div>Five overarching themes affected patient adherence to pressure ulcer preventative advice: Patient decision-making, difficulty implementing advice, carer involvement, trust in the nurse and the nursing approach. These factors were complex, individualised, dynamic, and context and time specific. How pressure ulcer avoidance was negotiated diverged according to the type of nursing approach adopted, which impacted on adherence.</div></div><div><h3>Conclusion</h3><div>The new conceptual model identifies the importance of an open, participatory nursing approach to support shared decision-making. It accommodates the dynamic nature of patient factors, which affect their ability to acquire and understand PU advice and adhere to preventative strategies.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100890"},"PeriodicalIF":2.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding recurrent pressure injuries: A scoping review of current research and risk factors","authors":"Li Du ,&nbsp;Ning Wang ,&nbsp;Juhong Pei ,&nbsp;Yanxia Jiao ,&nbsp;Jie Xu ,&nbsp;Xinyue Xu ,&nbsp;Anna Wen ,&nbsp;Lin Han ,&nbsp;Lin Lv","doi":"10.1016/j.jtv.2025.100886","DOIUrl":"10.1016/j.jtv.2025.100886","url":null,"abstract":"<div><h3>Aim</h3><div>To describe published studies on the current status of recurrent pressure injuries.</div></div><div><h3>Background</h3><div>Pressure injuries burden patients and the health care system, so it is essential to prevent their recurrence and prevent patients from experiencing secondary injury. However, most current studies focus on primary pressure injury and less on its recurrence.</div></div><div><h3>Design and methods</h3><div>We employed a scoping review methodology. From the database construction until December 9, 2024, we searched PubMed, Embase, Web of Science, CINAHL, and the Cochrane Library. Two researchers independently screened and extracted data.</div></div><div><h3>Results</h3><div>Twenty-eight articles met our criteria, most published after 2000. The included studies showed that 13 articles dealt with the definition of recurrent pressure injuries, but no uniform standard has been formed yet. The incidence of recurrent pressure injuries is 5.4 %–73.6 %. The most commonly reported site of recurrence is the ischium. The high-risk population for recurrence is the patient with spinal cord injury. Eleven studies described 26 risk factors for recurrent pressure injuries, of which albumin was the most commonly reported risk factor, followed by spinal cord injuries, age, hospital stay, and ulcer size. The 26 risk factors were summarised into five aspects: personal factors, social-environmental factors, disease-related factors, physiological and biochemical parameters, and Initial ulcer characteristics.</div></div><div><h3>Conclusions</h3><div>The incidence of recurrent pressure injuries varies widely, and specific definitions and standardised staging criteria must be further determined to improve clinical judgment and reporting accuracy. The risk factors for recurrent pressure injuries involve many aspects. Some studies have described local flaps and overall recurrence risk factors separately, and further verification is needed to determine whether there is a difference between the two.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100886"},"PeriodicalIF":2.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetic foot care behavior and self-efficacy levels in individuals with diabetic foot ulcers in Turkey","authors":"Emine Sezgunsay ,&nbsp;Murat Urkan ,&nbsp;Mustafa Deveci","doi":"10.1016/j.jtv.2025.100885","DOIUrl":"10.1016/j.jtv.2025.100885","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to explore the connection between demographic characteristics, diabetes-related knowledge, foot self-care behaviors, and self-efficacy levels in individuals with diabetic foot ulcers. Additionally, it investigated whether there is a correlation between foot care behaviors and self-efficacy levels among these individuals.</div></div><div><h3>Methods</h3><div>This descriptive and cross-sectional study was conducted with individuals who applied to a training and research hospital with a diabetic foot ulcer and received treatment between October 2019 and October 2020. Data were collected through the Patient Identification Characteristics Form, the Diabetes Management Self-Efficacy Scale, and the Foot Self-Care Behavior Scale. Percentage, mean, Mann-Whitney <em>U</em> test, Kruskal-Wallis test, and Spearman correlation analysis were used to analyze the data.</div></div><div><h3>Results</h3><div>The mean self-efficacy score among individuals with diabetic foot ulcers was 68.39 ± 14.03, while the mean foot self-care behavior score was 59.10 ± 10.13. Previous diabetes education, regular exercise, and educational status significantly influenced scores on both scales. Furthermore, a positive linear relationship was observed between foot self-care behaviors and self-efficacy levels in individuals with diabetic foot.</div></div><div><h3>Conclusions</h3><div>To enhance self-efficacy levels and promote foot self-care behaviors in individuals with diabetic foot ulcers, continuous education, and regular follow-up examinations are essential. Providing tailored care based on demographic characteristics and evolving health conditions related to diabetes is expected to reduce complications effectively.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100885"},"PeriodicalIF":2.4,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence rate and risk factors of intraoperative-acquired pressure injury in posterior interbody fusion: A retrospective study of a national inpatient sample database","authors":"Xuelian Wang ,&nbsp;Mengmeng Shao ,&nbsp;Jian Wang ,&nbsp;Xiaoshuang Liang ,&nbsp;Yuhang Chen ,&nbsp;Haofei Wang ,&nbsp;Jianlong Li","doi":"10.1016/j.jtv.2025.100873","DOIUrl":"10.1016/j.jtv.2025.100873","url":null,"abstract":"<div><h3>Background</h3><div>Intraoperative-acquired pressure injuries (IAPIs) are a common complication in posterior intervertebral fusion surgery, leading to adverse outcomes for patients. However, there is a lack of large-scale national database research analyzing the morbidity and associated risk factors of IAPIs in this surgical procedure.</div></div><div><h3>Methods</h3><div>This retrospective study analyzed data from the National Inpatient Sample (NIS) database from 2010 to 2019. Demographic, hospital, and patient characteristics were examined, including length of stay (LOS), total costs, in-hospital mortality, preoperative comorbidities, and complications.</div></div><div><h3>Result</h3><div>The overall incidence of IAPIs in posterior intervertebral fusion surgery was 0.2 % from 2010 to 2019. The annual occurrence of interbody fusion demonstrated an M-shaped trend, with rates of 0.2 % in 2010, 0.05 % in 2016, and 0.05 % in 2019. IAPIs were associated with increased preoperative complications, longer LOS, higher total hospitalization costs, and higher in-hospital mortality rates. Risk factors for IAPIs included comorbidities, large hospitals, urban hospitals, deficiency anemia, coagulation disorders, fluid electrolyte disorders, paralysis, and weight loss. Additionally, IAPIs were linked to medical complications such as sepsis, deep vein thrombosis, urinary tract infections, acute renal failure, shock, pneumonia, blood transfusion, and surgical complications such as cerebrospinal fluid leak. Elective admission was found to be a protective factor.</div></div><div><h3>Conclusion</h3><div>Identifying risk factors for IAPIs in posterior intervertebral fusion surgery can help identify high-risk patients and develop preventive measures. By targeting these risk factors, the incidence of IAPIs can be reduced, leading to improved patient outcomes.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100873"},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of pressure injuries in patients with spinal cord injury: A systematic review and meta-analysis","authors":"Jie Xu ,&nbsp;Yanxia Jiao ,&nbsp;Ning Wang ,&nbsp;Xinyue Xu ,&nbsp;Limei Yang ,&nbsp;Lin Han ,&nbsp;Lin Lv","doi":"10.1016/j.jtv.2025.100881","DOIUrl":"10.1016/j.jtv.2025.100881","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Objective&lt;/h3&gt;&lt;div&gt;To systematically evaluate the incidence of pressure injuries (PIs) in patients with spinal cord injury (SCI) and to provide a basis for preventing and treating PIs.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A systematic review and meta-analysis were performed according to the Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) guidelines. Electronic databases such as PubMed, Embase, Cochrane Library, Web of Science, China Knowledge Resource Integrated Database (CNKI), Wan-fang Database, Weipu Database (VIP), and the China Biomedical Database (CBM) were searched to collect cross-sectional and cohort studies related to PIs in SCI patients. All electronic literature sources were searched for relevant articles from inception to July 2024. Studies were independently assessed by two researchers and reviewed by a third. Data were extracted and presented in tabular form. The risk of bias was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist and the Agency for Healthcare Quality and Research (AHRQ) Cross-Sectional Study Evaluation Criteria. All data were analysed using Stata 16.0. The &lt;em&gt;I&lt;/em&gt;&lt;sup&gt;&lt;em&gt;2&lt;/em&gt;&lt;/sup&gt; statistics and random effects models were used to determine heterogeneity, and results were expressed as incidence with 95 % confidence intervals (&lt;em&gt;CI&lt;/em&gt;).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;11,754 articles were screened, and 35 studies involving 150,391 patients were finally included. The combined incidence of PIs in SCI patients was 28.8 % (95%&lt;em&gt;CI&lt;/em&gt;: 24.2 to 33.4). For different genders, the incidence of PIs in male SCI patients was 29.2 % (95 % CI: 20.4 to 38.1), while for female SCI patients, it was 25.2 % (95 % &lt;em&gt;CI&lt;/em&gt;: 16.1 to 34.3). The PI incidence rate in patients with SCI was 33.9 % (95 % &lt;em&gt;CI&lt;/em&gt;: 27.1 to 40.7) before 2005, 29.4 % (95 % &lt;em&gt;CI&lt;/em&gt;: 19.1 to 39.7) from 2006 to 2015, and 27.1 % (95 % &lt;em&gt;CI&lt;/em&gt;: 20.8 to 33.3) from 2016 to 2024. According to regional distribution data by country, the combined incidence of PIs in SCI patients was 34.3 % (95 % &lt;em&gt;CI&lt;/em&gt;: 21.0 to 47.6) in European countries, 20.9 % (95 % &lt;em&gt;CI&lt;/em&gt;: 12.8 to 28.9) in Asian countries, 43.3 % (95 % &lt;em&gt;CI&lt;/em&gt;: 16.5 to 70.1) in African countries, 25.0 % (95 % &lt;em&gt;CI&lt;/em&gt;: 15.9 to 34.0) in North American countries, and 65.3 % (95 % CI: 55.9–74.7) in South American countries. In 12 studies that reported the anatomical location of PIs in patients with SCI, 1113 patients developed 1836 PIs. The sacrococcygeal region had the highest number of these injuries, totalling 521 (28.8 %), followed by the sciatic tuberosity, with 233 (12.9 %), then, the heel, with 221 (12.3 %).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusion&lt;/h3&gt;&lt;div&gt;The study's results showed an overall incidence of PIs in patients with SCI of 28.8 %, significantly exceeding the average incidence rate in adults. We found that the incidence of PIs was higher in men than in women in patients with SCI. Therefore, clinical car","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100881"},"PeriodicalIF":2.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing sickle cell leg ulcer healing with combined photodynamic and photobiomodulation therapies: A pilot experience","authors":"Vitor Fortuna ,&nbsp;Gabriel F. Oliveira ,&nbsp;Livia M. Xavier ,&nbsp;Daniele V. Oliveira ,&nbsp;Jaqueline G. Lima ,&nbsp;Yasmin S. Oliveira ,&nbsp;Beatriz S. Costa ,&nbsp;Giselle B. Jesus ,&nbsp;Setondji C.M.A. Yahouedehou ,&nbsp;Elissandra M. Zanchin ,&nbsp;José Roberto Meyer ,&nbsp;José V. Meneses ,&nbsp;Marilda Souza Gonçalves ,&nbsp;Vanderlei S. Bagnato","doi":"10.1016/j.jtv.2025.100879","DOIUrl":"10.1016/j.jtv.2025.100879","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to evaluate the safety and efficacy of combined photodynamic therapy (PDT) and photobiomodulation (PBM) in treating sickle cell leg ulcers (SCLUs), with a focus on pain reduction and enhanced healing.</div></div><div><h3>Materials and methods</h3><div>In this prospective, open-label, uncontrolled pilot study, ten SCD patients with 17 chronic leg ulcers received PDT and PBM treatments. Ulcer severity, pain levels, and microbiome changes were monitored, and clinical data were analyzed using appropriate statistical methods.</div></div><div><h3>Results</h3><div>Among the treated ulcers, 64.7 % (11 out of 17) showed significant healing, with 9 ulcers achieving complete closure. The average reduction in ulcer size was significant, with a median healing time of 123 days. Pain levels decreased significantly in 82.3 % of treated ulcers (p &lt; 0.001), and a 75.4 % reduction in bacterial load was observed, alongside increased microbiome diversity (p &lt; 0.05). Elevated levels of IL-6 and PSGL-1 were associated with non-healing ulcers, indicating their potential as prognostic biomarkers.</div></div><div><h3>Conclusion</h3><div>The combined PDT and PBM therapy proved to be effective and safe for SCLUs, offering significant improvements in healing and pain reduction. These findings suggest that integrating PDT and PBM into standard care protocols could enhance the management of SCLUs.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100879"},"PeriodicalIF":2.4,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intensive care nurses' knowledge regarding medical device-related pressure injuries and factors affecting these: A descriptive and cross-sectional study","authors":"Münevver Sönmez ,&nbsp;Nur Güven Özdemir ,&nbsp;Şirin Harkın Gemicioğlu ,&nbsp;Ayşe Aydın","doi":"10.1016/j.jtv.2025.100880","DOIUrl":"10.1016/j.jtv.2025.100880","url":null,"abstract":"<div><h3>Aim</h3><div>Nurses play a fundamental role in preventing, treating, and reducing the incidence of medical device-related pressure injuries (MDRPIs). Therefore, assessing their level of knowledge on this subject is of utmost importance. The aim of this study is to determine intensive care nurses’ levels of knowledge regarding medical device-related pressure injuries and factors affecting these.</div></div><div><h3>Materials and methods</h3><div>This descriptive and cross-sectional study was conducted with 156 intensive care unit (ICU) nurses between October 2023 and March 2024. Data were collected using the Nurses Information Form, Medical Device Related Pressure Injury Knowledge Assessment Test (MDRPI-KAT).</div></div><div><h3>Results</h3><div>The nurses had a mean score of 9.05 ± 2.54 on the MDRPI-KAT, indicating an overall correct answer percentage of 56.5 %. It was determined that nurses scored the highest in the sub-dimension of “Selection and Suitability of Medical Devices” (87.5 %) and the lowest in the sub-dimension of “Special Patient Groups” (29.5 %). The total MDRPI-KAT score for female nurses is 1.031 times higher than that of male nurses (B = 1.031, p = 0.013). Additionally, nurses with a high school, bachelor's, or postgraduate level of education have a higher total MDRPI-KAT score compared to those with an associate degree (β = 2.393, p = 0.003; β = 2.114, p = 0.005; β = 3.101, p = 0.001). Furthermore, the total MDRPI-KAT score of nurses who believe that a nursing care protocol is necessary for the prevention of MDRPIs is 1.309 times higher than that of those who do not consider it necessary.</div></div><div><h3>Conclusion</h3><div>This study found that ICU nurses' knowledge regarding MDRPIs were insufficient. We identified gender, education level, and the perceived need for a nursing care protocol for the prevention of MDRPIs as variables that influence nurses' level of knowledge. To enhance nurses' knowledge about MDRPIs and ensure the provision of safe and high-quality skin care, we recommend that intensive care nurses receive continuous and practical training on MDRPIs. This should include innovative educational methods such as simulations and case analyses, as well as the organization of online courses and webinars.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100880"},"PeriodicalIF":2.4,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143594235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of topically applied MEBO in healing of traumatic oral ulcer: Randomized controlled trial","authors":"Amany Ahmed AlAraby ,&nbsp;Nadia Fathy Hassabou ,&nbsp;Wessam Ibrahim Shehab Eldin","doi":"10.1016/j.jtv.2025.100877","DOIUrl":"10.1016/j.jtv.2025.100877","url":null,"abstract":"<div><h3>Background</h3><div>MEBO is an analgesic and antibacterial natural agent. Sesame oil extract plays a positive effect in wound healing that may be attributed to its ability to scavenge free radicals and antioxidant properties.</div></div><div><h3>Material and methods</h3><div>In this study, MEBO was topically applied to the site of a traumatic oral ulcer to examine its therapeutic effect on pain relief and wound healing. Patients were randomly assigned into two equal groups: group I (MEBO), group II (control), (n = 15 patients each). Pain was recorded by using the Visual Analogue Scale (VAS), wound size was measured at days 2, 5, and 10. Cytological analysis was also performed using the superficial epithelial cell and keratinization indices.</div></div><div><h3>Results</h3><div>There was a statistically significant difference in VAS scores and wound size between MEBO group and control group (p ≤ 0.001). Cytological results of MEBO group showed a highly significant improvement (p ≤ 0.00001) in re-epithelization and keratinization indices over time.</div></div><div><h3>Conclusion</h3><div>Our results showed that the application of MEBO on traumatic ulcer sites has a significant improvement in wound healing and rapid enhancing effect on the re-epithelialization rate.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100877"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Twenty-one year trends in pressure injury in a Western Australian hospital","authors":"Linda L. Coventry ,&nbsp;Istvan Kabdebo ,&nbsp;Nicole Walsh ,&nbsp;Joelle Winderbaum ,&nbsp;Mark Jenkins ,&nbsp;Prachi Kaistha ,&nbsp;Diane E. Twigg ,&nbsp;Shirley Jansen ,&nbsp;Dimitri Beeckman","doi":"10.1016/j.jtv.2025.100878","DOIUrl":"10.1016/j.jtv.2025.100878","url":null,"abstract":"","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100878"},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143520341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}