{"title":"Comparative effects of epidermal and fibroblast growth factor-infused collagen patches on wound healing in a full-thickness rat model","authors":"Fahri Sabanciogullarindan , Mehmet Bozkurt , Nilsen Yildirim Erdogan , Yasar Samet Gokceoglu , Percin Karakol","doi":"10.1016/j.jtv.2025.100903","DOIUrl":"10.1016/j.jtv.2025.100903","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the effects of Epidermal Growth Factor (EGF)- and Fibroblast Growth Factor (FGF)-infused collagen patches on wound healing in an experimental rat model. The focus was on acute and chronic inflammation, granulation tissue formation, fibroblast maturation, re-epithelialization, neovascularization, and collagen remodeling.</div></div><div><h3>Methods</h3><div>Full-thickness cranial wounds (12 mm) were created on the dorsal regions of 21 male Wistar rats and divided into four groups: Group 1 (collagen patch alone), Group 2 (collagen + EGF), Group 3 (collagen + FGF). The kaudal defects served as a chronic wound model with secondary intention healing, monitored for 21 days. Tissue biopsies were collected on days 3, 7, and 21. Histopathological evaluation included inflammation scores, granulation tissue formation, fibroblast maturation, re-epithelialization, neovascularization, and Type 1/Type 3 collagen ratio. Data were analyzed using one-way ANOVA, Kruskal–Wallis test, and other appropriate post hoc tests. Statistical significance was set at p < 0.05.</div></div><div><h3>Results</h3><div>Acute inflammation significantly decreased in Group 3 on day 7 (p = 0.001), while chronic inflammation was minimal by day 21 in Groups 1 and 3. Group 2 showed the highest granulation tissue formation on day 21 (p < 0.05). Fibroblast maturation peaked in Group 3 on day 21 (p = 0.004). Re-epithelialization was complete in Groups 1 and 3 by day 21, significantly outperforming Group 2 (p < 0.005). Group 3 demonstrated superior collagen deposition and the highest Type 1/Type 3 collagen ratio (p < 0.05).</div></div><div><h3>Conclusions</h3><div>FGF-infused collagen patches significantly improved fibroblast maturation, epithelialization, and collagen remodeling, outperforming EGF and standalone collagen patches. These findings highlight the potential of FGF as a therapeutic agent in wound healing.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100903"},"PeriodicalIF":2.4,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143850543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ying Liu , Rong Hu , Peifang Li , Lin Zhang , Liqun Wang , Junhong Qu , Xingcui Pu , Ning Ning , Jiali Chen
{"title":"Factors influencing Patient engagement in preventing pressure injuries: A cross-sectional study in Orthopedic inpatients","authors":"Ying Liu , Rong Hu , Peifang Li , Lin Zhang , Liqun Wang , Junhong Qu , Xingcui Pu , Ning Ning , Jiali Chen","doi":"10.1016/j.jtv.2025.100902","DOIUrl":"10.1016/j.jtv.2025.100902","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to explore the level of patients’ engagement behaviours in preventing pressure injury (PI) and the influencing factors related to it.</div></div><div><h3>Background</h3><div>The importance of “Patient and Family Engagement” was recognized as one of the key components in the outline of the 2023 Global Patient Safety Report. PIs were common and concerning patient safety events in Orthopaedics department. Active patient participation behaviour can effectively prevent the occurrence of PIs.</div></div><div><h3>Method</h3><div>This was a cross-sectional study involving 366 participants from Orthopaedics in China who has high level of risk in PI. The behavioural level of patients' participation in PI prevention was measured using a research tool designed by the research team. Based on the theory of planned behaviour, the possible influencing factors were determined, and the corresponding research tools were selected for evaluation. Univariate analysis, correlation analysis and multiple stepwise regression were used to determine the influencing factors of patients’ participation behaviour with SPSS 25.0.</div></div><div><h3>Results</h3><div>The total score of orthopaedic inpatients participating in PI preventive behaviour was 89.45 ± 10.64, with a scoring rate of 85.19 % (actual score/maximum possible score × 100 %), indicating relatively high adherence. Multiple regression analysis revealed that social support showed the strongest positive association (β = 0.291, P < 0.001), suggesting enhanced support networks facilitate engagement. Participation attitude (β = 0.211, P < 0.001) and health literacy (β = 0.233, P < 0.001) were key cognitive facilitators. Unexpectedly, cohabitation with children exhibited negative correlation (β = −0.141, P = 0.001), potentially indicating caregiving role transfer. Inter-hospital transfers (β = −0.120, P = 0.004) and medium-length stays (4–7 days, β = −0.089, P = 0.010) were inversely related, possibly reflecting care continuity challenges. Social Security recipients demonstrated greater participation (β = 0.108, P = 0.009), highlighting socioeconomic influences.</div></div><div><h3>Conclusion</h3><div>Our findings may guide clinical healthcare providers to develop more targeted interventions to promote patient engagement in self-care, including encouraging family members to involve in PI prevention with patients, improving patients’ attitude of participation, and supporting more health education of PI prevention. It was a potential suggestion for patient participation behaviour in medical services to prevent other types of adverse events as well.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100902"},"PeriodicalIF":2.4,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review of the effects of far infrared radiation on muscle injury caused by centrifugal exercise","authors":"Lin Ren , Ran He","doi":"10.1016/j.jtv.2025.100900","DOIUrl":"10.1016/j.jtv.2025.100900","url":null,"abstract":"<div><h3>Objective</h3><div>Explore the recovery effect of FIR on high-intensity centrifugal contraction or lower limb muscle fiber injury caused by long-term endurance exercise.</div></div><div><h3>Methods</h3><div>Collect and organize relevant literature on FIR, and explore the recovery effect and possible mechanism of FIR intervention on subtle muscle fiber damage caused by exercise.</div></div><div><h3>Result</h3><div>FIR can reduce COX-2, inhibit PGE<sub>2</sub>, accelerate hydrogen peroxide clearance, alleviate pain caused by various conditions, promote cell proliferation, and increase blood flow; Among the two main processing tools of FIR, FIR lighting fixtures that are exposed to radiation for 30 min a day after exercise can effectively alleviate the human induced DOMS condition, while FIR clothing needs to be worn for 9 h a day to have the effect of slowing down DOMS.</div></div><div><h3>Conclusion</h3><div>FIR may be developed into one of the auxiliary strategies for warm-up before competitions and after intermission in the future.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100900"},"PeriodicalIF":2.4,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143838514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hamilton Dollaku , Mara Dalladonna , Marika Giuliano , Michele Rossi , Paola Barbetti , Maria Sipontina Marcolongo , Emanuele Buccione , Paolo Iovino , Claudio Macchi
{"title":"Randomized clinical trial of the efficacy of the EmoLED medical device in the treatment of stage 2 and stage 3 pressure ulcers: The RISE_UP study","authors":"Hamilton Dollaku , Mara Dalladonna , Marika Giuliano , Michele Rossi , Paola Barbetti , Maria Sipontina Marcolongo , Emanuele Buccione , Paolo Iovino , Claudio Macchi","doi":"10.1016/j.jtv.2025.100895","DOIUrl":"10.1016/j.jtv.2025.100895","url":null,"abstract":"<div><h3>Aim of the study</h3><div>Pressure ulcers are an important public health issue, impacting quality of life and causing health deterioration. Blue light photobiomodulation has been shown promoting wound healing in vascular, diabetic, rheumatologic ulcers and lesions in spinal cord injury patients. Based on these preliminary results, this study was developed to assess the effectiveness of blue light therapy in second and third stage pressure ulcers.</div></div><div><h3>Materials and methods</h3><div>This study was a randomized controlled trial enrolling hospitalized patients with poor mobility. The intervention group included blue light treatment in addition to standard care, three times a week, for 4 consecutive weeks. The primary objective is the difference in the healing process by measuring the average difference of the lesion's PUSH score between the first and the last visit.</div></div><div><h3>Results</h3><div>The analysis shows that the mean PUSH reduction and the probability of belonging to responder patients were higher in the treatment group. A latent profile analysis that identifies two trajectory classes based on treatment response, shows an association in the probability of following best trajectory for the treatment group (30 % vs 2 %).</div></div><div><h3>Conclusions</h3><div>The result shows that blue light photobiomodulation promotes recovery of tissue repair in pressure ulcers, and in stabilizing wounds that would otherwise worsen despite standard of care treatment. This therapy may be a valuable contribution to the daily management of pressure lesions since it has an excellent safety profile and the addition of this therapy to a treatment program may speed healing, improving the quality of life.</div><div>(<span><span>Clinicaltrials.gov</span><svg><path></path></svg></span> Ref. numb.: NCT05130814)</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100895"},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of the structural and histopathological challenges of binary electrospun PET-based nanofibers for tissue engineering applications","authors":"Afsaneh Jahani , Davod Mohebbi-Kalhori , Farkhonde Sarhaddi , Gholam Hosein Kazemzadeh , Reza Taheri , Mehdi Ahmadi , Nafiseh Jirofti","doi":"10.1016/j.jtv.2025.100888","DOIUrl":"10.1016/j.jtv.2025.100888","url":null,"abstract":"<div><div>Tissue engineering and regenerative medicine aim to address tissue lesions and organ degenerations, enhancing clinical outcomes by restoring damaged tissues and functionalities. Recent progress in materials science and medicine has led to the development of regenerative engineering, revolutionizing the production of polymeric artificial scaffolds by electrospinning method, which mimic the extracellular matrix (ECM). Polyurethane (PU) is recognized for its elastic nature, comprising soft and hard segments, and possesses bioactive as well as biocompatible properties. Polycaprolactone (PCL), on the other hand, is a non-toxic polymer with a viscous nature, known for its favorable mechanical properties. This study focuses on the comprehensive histological evaluation of binary electrospun PET-based nanofiber scaffolds, as widely used in tissue engineering. The structural analysis involved FE-SEM imaging, porosity measurement, FTIR, and DSC examinations. In vitro assessments included degradation rates, water uptake, cell viability, morphological cell examination, and cell attachment studies. Additionally, scaffolds were subcutaneously implanted in rats for pathological examination. After a 30 days implantation period, histological and pathological parameters such as edema, inflammation, foreign body giant cell reaction, fibrosis, necrosis, and calcification were evaluated. The results highlight the successful application of blend electrospinning in producing PET/PCL and PET/PU nanofiber scaffolds with various composition ratios. FE-SEM imaging revealed uniform nanostructures without bead formation. Histological analysis showed favorable biocompatibility, with the PET/PCL (25:75) composition demonstrating superior structural characteristics compared to other ratios. The cell studies indicated that PET-based nanofiber scaffolds exhibited suitable cell viability and attachment, underscoring their potential for tissue engineering applications.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100888"},"PeriodicalIF":2.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eric McMullen , Rokhshid Aflaki , Pranav Jignesh Khatri , Dea Metko , Kyle Storm , Abu Bakar Butt , Mahan Maazi , Raghav Gupta , Rajan Grewal , Trevor Champagne
{"title":"Machine learning methods for determining skin age: A systematic review","authors":"Eric McMullen , Rokhshid Aflaki , Pranav Jignesh Khatri , Dea Metko , Kyle Storm , Abu Bakar Butt , Mahan Maazi , Raghav Gupta , Rajan Grewal , Trevor Champagne","doi":"10.1016/j.jtv.2025.100887","DOIUrl":"10.1016/j.jtv.2025.100887","url":null,"abstract":"<div><h3>Aim</h3><div>This systematic review explores how machine learning is used in determining skin aging, aiming to evaluate accuracy, limitations, and gaps in the current literature.</div></div><div><h3>Materials and methods</h3><div>OVID Embase, OVID Medline, IEEE Xplore, and ACM Digitial Library were searched from inception to March 16, 2024.</div></div><div><h3>Results</h3><div>A total of 1467 non-duplicate articles were screened, and 27 were ultimately included in the systematic review. The machine learning models exhibited a range of accuracies from a mean absolute error of 2.30–8.16 years. The most common approach was full facial image analysis, followed by non-image-based studies utilizing biomarkers such as the methylome and the proteome. The incorporation of dynamic facial expressions in the analysis was shown to improve the accuracy of age estimation, with a mean absolute error of 3.74. Confocal microscopy demonstrated potential for accurate skin aging estimation, with some studies achieving up to 85 % accuracy. Many studies were found with high PROBAST risk of bias scores, most commonly due to small sample sizes.</div></div><div><h3>Conclusion</h3><div>Future studies should aim for greater diversity in ethnicity and variables within datasets to improve generalizability.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100887"},"PeriodicalIF":2.4,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143748702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qianwen Chao , Juhong Pei , Yuting Wei , Zhuang Yang , Xiaorui Wang , Li Du , Lin Han
{"title":"Evaluation methods of pressure injury stages: A systematic review and meta-analysis","authors":"Qianwen Chao , Juhong Pei , Yuting Wei , Zhuang Yang , Xiaorui Wang , Li Du , Lin Han","doi":"10.1016/j.jtv.2025.100894","DOIUrl":"10.1016/j.jtv.2025.100894","url":null,"abstract":"<div><h3>Background</h3><div>Pressure injury is prevalent in clinical settings and demands precise staging for optimal care. Subjectivity and imprecision in traditional visual assessments have sparked the creation of advanced technology-based evaluation tools.</div></div><div><h3>Aims</h3><div>To systematically assess pressure injury staging methods, analyze their evaluation results, and provide reference for clinical practice.</div></div><div><h3>Design</h3><div>Systematic review and meta-analysis.</div></div><div><h3>Data sources</h3><div>PubMed, Embase, Cochrane Library, Web of Science, CINAHL, and manual searches of academic journals and conference proceedings were utilized.</div></div><div><h3>Methods</h3><div>The study conducted a systematic search of databases in April 2024, utilizing Endnote X9 to document findings. Two reviewers independently extracted data and evaluated its quality using the QUADAS-2 tool. The meta-analysis, conducted in Meta-disc, focused on metrics such as AUC, sensitivity, and specificity. Heterogeneity among the studies was assessed using Cochran's Q and <em>I</em><sup><em>2</em></sup> tests.</div></div><div><h3>Results</h3><div>This review screened 15312 articles and ultimately included 15 studies. These studies described methods for pressure injury staging, including visual assessment, 29 machine learning models, and human-model integrated evaluation. The accuracy of traditional visual assessment was relatively low and showed significant variability. Eight studies involving 24 machine learning models were included in the meta-analysis, demonstrating significantly high accuracy, with an AUC of 0.93, and the combined sensitivity, specificity, and diagnostic odds ratio were 0.81, 0.87, and 20.48, respectively.</div></div><div><h3>Conclusion</h3><div>The review underscores the advantages of machine learning in diagnosing pressure injuries, offering higher accuracy over traditional methods. Integrating clinical expertise with machine learning enhances medical service quality and efficiency.</div></div><div><h3>Prospero registration number</h3><div>CRD42023462951.</div></div><div><h3>Prospero registration link</h3><div><span><span>crd.york.ac.uk/prospero/display_record.php?ID=CRD42023462951</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100894"},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Esra Özkan , Burçak Şahin Köze , Meryem Yavuz van Giersbergen
{"title":"Effectiveness of plant and animal-based interventions in preventing and reducing pressure injuries: A systematic review and meta-analysis","authors":"Esra Özkan , Burçak Şahin Köze , Meryem Yavuz van Giersbergen","doi":"10.1016/j.jtv.2025.100893","DOIUrl":"10.1016/j.jtv.2025.100893","url":null,"abstract":"<div><h3>Background</h3><div>Pressure injuries (PIs) are a significant concern among the elderly and bedridden patients, often resulting from prolonged pressure on the skin. Various interventions, including plant and animal-based therapies, are used to prevent and treat PIs. However, there is a lack of comprehensive understanding of the effectiveness of these natural interventions.</div></div><div><h3>Aim</h3><div>This study aims to systematically review and conduct a meta-analysis of studies using plant and animal-based interventions to prevent and treat pressure injuries.</div></div><div><h3>Methods</h3><div>A systematic review and meta-analysis were performed according to the PRISMA guidelines. Searches were conducted in PubMed, Web of Science, SCOPUS, and Cochrane databases using keywords related to pressure injuries and natural interventions. Studies published between 2003 and 2023 were included. The inclusion criteria were experimental, quasi-experimental, and case-control studies. Data extraction and quality assessment were performed independently by two researchers. The effect size was calculated using Hedges' g, and heterogeneity was assessed using Cochrane Q and I<sup>2</sup> tests.</div></div><div><h3>Results</h3><div>A total of 13,563 records were identified, with 20 studies meeting the inclusion criteria after screening and full-text review. The total sample size was 2541 participants. The meta-analysis revealed a significant overall effect size (g = −0.614, 95 % CI: −0.890 to −0.337) indicating moderate effectiveness of plant and animal-based interventions in preventing and reducing PIs. Aloe vera, olive oil, and fish oil showed significant effects with p-values <0.05. High heterogeneity was observed among the studies (Q = 91.007, p < 0.05; I<sup>2</sup> = 79.123 %), leading to the use of a random effects model.</div></div><div><h3>Conclusions</h3><div>Plant and animal-based interventions are moderately effective in preventing and reducing pressure injuries. These findings support the integration of natural therapies into clinical practice for PI management. Further research is needed to standardize protocols and explore the long-term effects of these interventions.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100893"},"PeriodicalIF":2.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hannah Wilson , Aglecia Moda Vitoriano Budri , Liane Araujo Teixeira , Pinar Avsar , Linda Nugent , Niamh Dillon , Declan Naughton , Wendy Chaboyer , Tom O'Connor , Killian Walsh , Sharon Latimer , Zena Moore
{"title":"Synthesising the evidence for patient and public involvement in pressure ulcer research: A scoping review protocol","authors":"Hannah Wilson , Aglecia Moda Vitoriano Budri , Liane Araujo Teixeira , Pinar Avsar , Linda Nugent , Niamh Dillon , Declan Naughton , Wendy Chaboyer , Tom O'Connor , Killian Walsh , Sharon Latimer , Zena Moore","doi":"10.1016/j.jtv.2025.100892","DOIUrl":"10.1016/j.jtv.2025.100892","url":null,"abstract":"<div><h3>Introduction</h3><div>There is a growing shift toward greater inclusion of patients and the public in the design, conduct, and implementation of research to ensure it is more meaningful, relevant and impactful. This involvement creates a partnership in which patients and the public contribute to decisions throughout the research lifecycle. While the impact and importance of patient and public involvement (PPI) in research is becoming increasingly recognised, the extent of PPI in pressure ulcer (PU) research has yet to be fully established. This scoping review aims to provide insights into how PPI has been included and reported in PU research, ultimately placing a spotlight on the impact and importance of reporting PPI to guide future PU research.</div></div><div><h3>Methods and analysis</h3><div>Through synthesising literature from a diverse global landscape, this scoping review aims to achieve the following objectives (1) To explore and map the stage(s) of the PU research cycle where PPI has been incorporated (2) To identify and describe the range of participatory methods, including frameworks, guidelines, or tools, that have been used to facilitate the involvement of patients and the public in PU research. (3) To identify and synthesise reporting impacts of including PPI in PU research, and (4) To map and analyse the terminology commonly used to describe PPI in PU research.</div><div>The Joanna Briggs Institute scoping review methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for scoping reviews framework will guide the conduct and reporting of this review. Nine databases will be included in the search strategy and all articles will be independently screened for eligibility by two authors. Data from eligible articles will be extracted using a pre-defined data extraction table, and the results will be analysed and synthesised using the PAGER (Patterns, Advances, Gaps, Evidence for practice and Research recommendations) framework.</div></div><div><h3>Ethics and dissemination</h3><div>Ethics approval will not be required considering the nature of this scoping review. PPI advisory partners will be consulted for disseminating the results in a format that is accessible and understood by a layperson, in order to communicate the findings to a wide audience and diverse communities. This scoping review will be published in a peer reviewed journal and results will be disseminated at local national and international conferences.</div></div><div><h3>Registration</h3><div>This scoping review is registered on the Open Science Framework (<span><span>https://doi.org/10.17605/OSF.IO/JHT34</span><svg><path></path></svg></span>). As is typical with scoping reviews, this protocol may evolve over time. Any updates will be documented on the Open Science Framework platform, along with a clear rationale for the changes.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 2","pages":"Article 100892"},"PeriodicalIF":2.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143706508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Herminigildo II Lo , Eleanor Hollywood , Rosemarie Derwin
{"title":"Bridging the gap: ICU nurses’ experiences in detecting pressure injuries across diverse skin tones","authors":"Herminigildo II Lo , Eleanor Hollywood , Rosemarie Derwin","doi":"10.1016/j.jtv.2025.100891","DOIUrl":"10.1016/j.jtv.2025.100891","url":null,"abstract":"<div><h3>Background</h3><div>Pressure Injury detection remains a challenge in patients with darker skin tones due to the absence of visible erythema, resulting in delayed diagnosis and poorer patient outcomes. Despite international guidelines, nurses face barriers in early recognition due to knowledge gaps and inadequate training in skin tone diversity. A timely assessment is critical for effective treatment. This necessitates that healthcare professionals recognise how early pressure ulcer signs may present in patients of all skin tone types.</div></div><div><h3>Aim</h3><div>To explore ICU nurses’ experiences in assessing pressure areas in patients with dark skin tones and identify challenges and solutions.</div></div><div><h3>Methodology</h3><div>Following ethical approval, semi-structured interviews were conducted with 11 ICU Nurses. Interview data were analysed using thematic analysis using NVivo software.</div></div><div><h3>Findings</h3><div>Three key themes emerged: (1) Gaps in education and training on diverse skin tones, (2) Challenges in early detection due to “white normativity” in assessment tools, and (3) The need for inclusive education and advanced diagnostic tools to mitigate disparities.</div></div><div><h3>Conclusion</h3><div>Urgent improvements in nursing curricula and clinical training are required to ensure equitable pressure injury detection for all skin tones. The study advocates for greater inclusivity in educational materials, continuous professional development, and the integration of advanced tools like infrared thermography and subepidermal moisture scanners.</div></div>","PeriodicalId":17392,"journal":{"name":"Journal of tissue viability","volume":"34 3","pages":"Article 100891"},"PeriodicalIF":2.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}