Journal of the European Academy of Dermatology and Venereology最新文献

{"title":"Evaluation of liver fibrosis by transient elastography in Brazilian patients with psoriasis using methotrexate.","authors":"Mariana Dos Santos Pereira, Daniela Kampel Stolnicki, Luna Azulay-Abulafia, Renata de Mello Perez, Carlos Antônio Rodrigues Terra Filho, João Carlos Regazzi Avelleira","doi":"10.1111/jdv.20654","DOIUrl":"https://doi.org/10.1111/jdv.20654","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the environmental sustainability of dermatology conferences.","authors":"P N Lim, T Griffiths, R Sheppeard, A Gan, A Wernham, S Tso","doi":"10.1111/jdv.20652","DOIUrl":"https://doi.org/10.1111/jdv.20652","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Passive versus active educational interventions for nevus and melanoma classification: A randomized controlled study.","authors":"M Spadafora, R Pampena, K Peris, L Del Regno, L Cornacchia, M C Fargnoli, C Pellegrini, P Quaglino, S Ribero, P G Calzavara-Pinton, M C Arisi, M Mirra, M Raucci, A Fusco, S Kaleci, J Chester, G Pellacani, C Longo","doi":"10.1111/jdv.20649","DOIUrl":"https://doi.org/10.1111/jdv.20649","url":null,"abstract":"<p><strong>Backgrounds: </strong>Patients or family members first notice around 50% of primary melanoma lesions. Targeted educational campaigns for non-medical individuals improve melanoma detection rates, but the most effective initiatives are unclear.</p><p><strong>Objectives: </strong>To compare the efficacy of passive versus active intervention for non-medical individuals in classifying nevi and melanomas.</p><p><strong>Methods: </strong>A multicentric randomized controlled study randomly assigned subjects to receive active intervention (a dermatologist explaining basic rules for melanoma detection) or passive intervention (subject independently reading the basic rules). Subjects were asked to classify 60 clinical photos of nevi and melanomas as 'at risk' of malignancy and nominated the rule(s) they applied at 3 time points-before (T0), immediately following (T1), and 30 ± 2 days after (T2) the educational intervention.</p><p><strong>Results: </strong>We randomized 364 patients. We included in the analysis 336 subjects (female 61.3%, 156 in the passive and 180 in the active intervention group) with a mean age of 44.5 years. Overall, detection rates of lesions 'at risk' improved from 71.2% (T0) to 86.4% (T1). At T2, detection rates were significantly higher after active intervention (83.7% vs. 86.8%, p = 0.017). Although an overall improvement was described after both interventions, rates of correct responses according to lesion-specific features were significantly higher in the active intervention group for lesions that met ugly duckling (UD) rule criteria at T1 and both rules (ABCDE and UD rules) criteria at T2. Correct (full or partial) rule applications were observed in 80% at T1 (40.2% and 38.4%, respectively) and at T2 (40.4% and 37.8%, respectively), with significantly higher correct rule application in the active group at T1 (p = 0.001) and T2 (p = 0.03).</p><p><strong>Conclusions: </strong>Active educational intervention is more effective than passive education in improving nevi and melanomas classification and correct rule application in non-medical individuals, with stable performance observed over time.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anorectal melanoma: Clinico-pathological features of a rare and aggressive malignancy in a multicentric study.","authors":"Giovanni Paolino, Giulio Tosti, Domenico Mascagni, Matteo Riccardo Di Nicola, Mario Valenti, Marco Ardigò, Carmen Cantisani, Antonio Podo Brunetti, Chiara Eberspacher, Laura Giacomelli, Vincenzo Russo, Rossella Melcarne, Massimiliano Mistrangelo, Pietro Quaglino, Rebecca Senetta, Arcangelo Picciariello, Leonardo Vincenti, Daniela Rega, Paolo Delrio, Corrado Caracò, Mariarosaria Portinaio, Giuseppe Damiano, Alessandra Bulotta, Nathalie Rizzo, Stefano Arcieri, Franco Rongioletti, Andrea Carugno, Sofia Maria Di Ciaccio, Rosa Falcone, Francesco Ricci, Riccardo Pampena, Santo Raffaele Mercuri","doi":"10.1111/jdv.20647","DOIUrl":"https://doi.org/10.1111/jdv.20647","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term scarring after Monkeypox virus infection in 40 men who have sex with men.","authors":"Juliette Salvia Prats, Vincent Bérot, Agathe Nouchi, Justin Destoop, Elise Ouedraogo, Camille Aubron-Olivier, Valérie Pourcher, Gentiane Monsel, Romain Palich","doi":"10.1111/jdv.20643","DOIUrl":"https://doi.org/10.1111/jdv.20643","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnic disparities in the treatment of port-wine stains in patients with Sturge-Weber syndrome.","authors":"Sabrina Duran, Iraj Hasan, Lauren Parsons, Wei Fang, Zachary Zinn","doi":"10.1111/jdv.20645","DOIUrl":"https://doi.org/10.1111/jdv.20645","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Completed suicide in patients with skin disease: A systematic review and meta-analysis.","authors":"B Hrvatin Stancic, M A S Henning, N Eriksen, J Emilie Dornonville de la Cour, D M L Saunte, G B E Jemec","doi":"10.1111/jdv.20609","DOIUrl":"https://doi.org/10.1111/jdv.20609","url":null,"abstract":"<p><strong>Background: </strong>Several skin diseases have been associated with suicidality. However, the term 'suicidality' encompasses ideation, which weakens the conclusions. In contrast, the much stronger endpoint of completed suicide and skin disease remains ambiguous.</p><p><strong>Objective: </strong>To determine the risk of completed suicide in adult patients with skin diseases.</p><p><strong>Methods: </strong>The Pubmed, Embase and PsycINFO databases were performed from inception up to June 2023. All original studies in English with a minimum of 10 adult patients that assessed the relationship between a skin disease and death by suicide, were eligible for inclusion.</p><p><strong>Results: </strong>Thirty-seven met the inclusion criteria. Owing to expected interstudy variations, a random effects model was used. A total of 13 skin diseases were identified: 17 population-based high-quality studies, 3,800,748 patients with skin disease, and 33,722,675+ controls were included in the meta-analysis (MA). Each skin disease was analysed separately. Psoriasis: six studies were included in the MA (odds ratio (OR): 1.42, 95% confidence interval (CI) (0.76; 2.68) and found no association. Dermatitis: five studies were included in the MA OR: 1.54, 95% CI (0.57; 4.17) and found no association. Melanoma: four studies were included in the MA, which found an association between melanoma and suicide Standardized mortality rate (SMR): 2.89, 95% CI (1.97; 3.81). Non-melanoma skin cancer: two studies were included in the MA; female patients showed an increased risk of completed suicide compared to the control group SMR: 1.30, 95% CI (1.12; 1.49). In patients with hidradenitis suppurativa, two studies were included in the MA OR: 2.86, 95% CI (1.56; 5.24) and showed a positive association between HS and completed suicide.</p><p><strong>Conclusions: </strong>Suicidality should be considered by physicians when treating dermatological disease, especially when treating patients with hidradenitis suppurativa and melanoma. The association between other skin diseases and completed suicide remains unclear, and further research is indicated.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143649412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carbon footprint analyses: A valuable tool for dermatology journals to pioneer sustainable practices.","authors":"Eugene Tan, Dennis Niebel, Misha Rosenbach","doi":"10.1111/jdv.20644","DOIUrl":"https://doi.org/10.1111/jdv.20644","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review of checkpoint inhibitor-induced epidermal necrolysis.","authors":"Rebecca Creamer, Freya Hamar-Davies, Mark Harries, Daniel Creamer","doi":"10.1111/jdv.20621","DOIUrl":"https://doi.org/10.1111/jdv.20621","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haematopoietic stem cell transplant in cutaneous T-cell lymphomas: A multicentre propensity-score matched study.","authors":"Lía Bejarano, Mercè Grau-Pérez, Marina Paíno-Román, María Pilar García Muret, Mercedes Morillo, Cristina Muniesa, Juan Torre-Castro, M Teresa Estrach, Elena Amutio Díez, Rosa Mª Lzu Belloso, Yeray Peñate, Constanza Martínez-Mera, Rafael Botella-Estrada, Miren Josune Michelena Eceiza, Pablo L Ortiz Romero, Mar Blanes, Ricardo Fernández-de-Misa, Lucía Prieto-Torres, María Elisabet Parera Amer, Helena Iznardo, Carlos Moreno-Vílchez, Octavio Servitje, Ignacio García-Doval, Javier Cañueto","doi":"10.1111/jdv.20638","DOIUrl":"https://doi.org/10.1111/jdv.20638","url":null,"abstract":"<p><strong>Background: </strong>Advanced cutaneous T-cell lymphomas (CTCL) are rare, generally refractory to therapeutic options, and have a poor prognosis. Haematopoietic stem cell transplantation (HSCT), mainly allogeneic HSCT (allo-HSCT), is considered a potentially curative option in CTCL refractory to other therapies. However, around half of patients relapse, and allo-HSCT is associated with significant adverse events. The available evidence on the usefulness of HSCT in CTCL generally comes from isolated cases and case series with a limited number of patients.</p><p><strong>Objective: </strong>Our aim was to evaluate the outcome of patients undergoing HSCT for advanced primary CTCL in Spain in a real-world environment and to compare their survival with that of similar patients who did not receive HSCT.</p><p><strong>Methods: </strong>We performed a retrospective observational study nested within the Primary Cutaneous Lymphoma Registry (RELCP) of the Spanish Academy of Dermatology and Venereology, collecting data on all patients receiving HSCT. Then, we performed propensity score matching (PSM) to pair HSCT patients with non-HSCT patients, adjusting for diagnosis, highest disease stage and age at diagnosis. We then performed survival analysis by means of Cox regression.</p><p><strong>Results: </strong>Of 2848 patients included in the RELCP, 51 patients underwent HSCT. Thirty-six patients (70.6%) achieved a complete response and seven patients (13.7%) partial response. Relapse was developed by 56.9% of patients, and 39.2% died (19.6% due to disease progression and 15.7% due to HSCT complications, mainly graft-versus-host disease (GVHD) and sepsis). Overall survival (OS) after HSCT at 5 years was 58.9%. No differences in OS were found between HSCT and non-HSCT groups.</p><p><strong>Conclusions: </strong>We did not observe a survival benefit among HSCT patients compared to non-HSCT patients within the RELCP cohort. This could be due to patients having received a mean of 6.3 lines of treatment before HSCT. Larger studies might help identify subgroups of patients who might benefit from HSCT.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143597103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}