{"title":"Reply to 'EuroGuiderm guideline on lichen sclerosus-Treatment of lichen sclerosus'.","authors":"G Kravvas, R Watchorn, A Spencer, C B Bunker","doi":"10.1111/jdv.20596","DOIUrl":"https://doi.org/10.1111/jdv.20596","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivia Bochnig, Thomas Giese, Judith Fischer, Katalin Komlosi, Silvia Mihalceanu, Hagen Ott, Knut Schäkel
{"title":"Immunoprofiling to guide treatment decision in SAM syndrome.","authors":"Olivia Bochnig, Thomas Giese, Judith Fischer, Katalin Komlosi, Silvia Mihalceanu, Hagen Ott, Knut Schäkel","doi":"10.1111/jdv.20597","DOIUrl":"https://doi.org/10.1111/jdv.20597","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automated detection of in-hospital drug hypersensitivity reactions using a privacy-preserving large language model.","authors":"Frédéric Dezoteux, Baptiste Mille, Lucas Shorten, Léa Dehame, Albane Badet, Delphine Staumont-Sallé, Johana Bene, Marie-Amélie Rispal, Aghiles Hamroun, Bastien Le Guellec","doi":"10.1111/jdv.20599","DOIUrl":"https://doi.org/10.1111/jdv.20599","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Syphilis maligna: Uncommon presentation of secondary syphilis.","authors":"Hui-En Chuo, Yu-Hung Wu","doi":"10.1111/jdv.20593","DOIUrl":"https://doi.org/10.1111/jdv.20593","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruth Cova-Martín, Javier Perez-Bootello, Angela Hermosa-Gelbard, Alba Gomez Zubiaur, Ramon Pigem Gasos, Sergio Vaño-Galvan, David Saceda-Corralo
{"title":"Hair transplantation in folliculitis decalvans: Outcome description in a multicentre series of 11 patients.","authors":"Ruth Cova-Martín, Javier Perez-Bootello, Angela Hermosa-Gelbard, Alba Gomez Zubiaur, Ramon Pigem Gasos, Sergio Vaño-Galvan, David Saceda-Corralo","doi":"10.1111/jdv.20558","DOIUrl":"https://doi.org/10.1111/jdv.20558","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L Ambrosio, C Retrosi, M Agozzino, C Cantisani, N di Meo, G Di Lella, R Giuffrida, S Guida, S Lembo, C Longo, I Zalaudek, G Pellacani, C Conforti
{"title":"Treatment of progressive locally advanced and metastatic basal cell carcinoma after two lines of treatment with hedgehog inhibitors and anti-PD1: The role of sonidegib rechallenge.","authors":"L Ambrosio, C Retrosi, M Agozzino, C Cantisani, N di Meo, G Di Lella, R Giuffrida, S Guida, S Lembo, C Longo, I Zalaudek, G Pellacani, C Conforti","doi":"10.1111/jdv.20559","DOIUrl":"https://doi.org/10.1111/jdv.20559","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deval Mehta, Clare Primiero, Brigid Betz-Stablein, Toan D Nguyen, Yaniv Gal, Adrian Bowling, Martin Haskett, Maithili Sashindranath, Paul Bonnington, Victoria Mar, H Peter Soyer, Zongyuan Ge
{"title":"Multi-task AI models in dermatology: Overcoming critical clinical translation challenges for enhanced skin lesion diagnosis.","authors":"Deval Mehta, Clare Primiero, Brigid Betz-Stablein, Toan D Nguyen, Yaniv Gal, Adrian Bowling, Martin Haskett, Maithili Sashindranath, Paul Bonnington, Victoria Mar, H Peter Soyer, Zongyuan Ge","doi":"10.1111/jdv.20551","DOIUrl":"https://doi.org/10.1111/jdv.20551","url":null,"abstract":"<p><strong>Background: </strong>The surge in AI models for diagnosing skin lesions through image analysis is notable, yet their clinical implementation faces challenges. Common limitations include an over reliance on dermoscopy, lack of real-world applicability when only binary output (e.g. benign/malignant) is offered and low accuracy when faced with rare skin conditions.</p><p><strong>Objective: </strong>To address these common constraints associated with limited diagnostic output, and applicability to real-world settings.</p><p><strong>Methods: </strong>We developed an All-In-One Hierarchical-Out of Distribution-Clinical Triage (HOT) AI model for skin lesion analysis. Trained on a large dataset of ~208,000 lesion images, our HOT AI model generates three outputs: a hierarchical three-level prediction, an alert for out-of-distribution (OOD) images and a recommendation for dermoscopy to improve diagnostic prediction.</p><p><strong>Results: </strong>Our hierarchical prediction output provides a binary level 1 prediction (benign/malignant), Level 2 prediction of eight possible categories (e.g. melanocytic and keratinocytic) and a more definitive Level 3 prediction from 44 lesion categories. The model produced high sensitivity for Level 1 prediction (88.14% CI: 87.42-88.51); however, significantly lower for Level 3 prediction (63.90%, CI: 62.27-65.61). By relying on all three prediction levels for consensus, Level 1 false-positives were reduced by 20-25%, and false-negatives were decreased by 11-13% of cases. OOD detection was benchmarked against previous landmark models and outperformed comparative models. Lastly, 44% of images were recommended for dermoscopy, and with additional image input, Level 3 sensitivity increased from 48.13% (CI:45.08-49.57) to 52.54% (CI:50.25-55.04).</p><p><strong>Conclusion: </strong>Our HOT-AI model attempts to address common challenges in existing models by combining three tasks in one model to increase accuracy and clinical utility. By providing a more nuanced prediction, and alert for OOD, the model output provides greater explainability of the AI decision process. Prospective clinical testing is required to measure how this additional output impacts user trust, and how the model performs in a real-world setting.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143365181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Andremasse, J Anriot, G Duru, V Mismetti, J L Perrot, L Thomas
{"title":"Creation and evaluation of an online dermoscopy test for self-evaluation of competences in diagnosis of skin cancer.","authors":"C Andremasse, J Anriot, G Duru, V Mismetti, J L Perrot, L Thomas","doi":"10.1111/jdv.20573","DOIUrl":"https://doi.org/10.1111/jdv.20573","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on 'Beyond the scoreboard: Coaches' UV-related skin cancer knowledge in outdoor sports'.","authors":"Luo-Wei Chan, Shih-Hao Huang, Jian-Chih Chen, Chia-Hao Hsu","doi":"10.1111/jdv.20567","DOIUrl":"https://doi.org/10.1111/jdv.20567","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Romain Nicolle, Laura Russell, Véronique Abadie, Patrick Nitschke, Christine Bole, Simon-Pierre Guay, Thi Tuyet Mai Nguyen, Stéphanie Leclerc-Mercier, Stanislas Lyonnet, Julie Steffann, Philippe M Campeau, Jacob Mashiah, Christine Bodemer, Smail Hadj-Rabia, Jeanne Amiel
{"title":"Expanding PIGM-related disorders to coding mutations.","authors":"Romain Nicolle, Laura Russell, Véronique Abadie, Patrick Nitschke, Christine Bole, Simon-Pierre Guay, Thi Tuyet Mai Nguyen, Stéphanie Leclerc-Mercier, Stanislas Lyonnet, Julie Steffann, Philippe M Campeau, Jacob Mashiah, Christine Bodemer, Smail Hadj-Rabia, Jeanne Amiel","doi":"10.1111/jdv.20578","DOIUrl":"https://doi.org/10.1111/jdv.20578","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}