Nicholas R Kurtansky, Clare A Primiero, Brigid Betz-Stablein, Marc Combalia, Pascale Guitera, Allan Halpern, Jonathan Kentley, Harald Kittler, Konstantinos Liopyris, Josep Malvehy, Christoph Rinner, Philipp Tschandl, Jochen Weber, Veronica Rotemberg, H Peter Soyer
{"title":"Effect of patient-contextual skin images in human- and artificial intelligence-based diagnosis of melanoma: Results from the 2020 SIIM-ISIC melanoma classification challenge.","authors":"Nicholas R Kurtansky, Clare A Primiero, Brigid Betz-Stablein, Marc Combalia, Pascale Guitera, Allan Halpern, Jonathan Kentley, Harald Kittler, Konstantinos Liopyris, Josep Malvehy, Christoph Rinner, Philipp Tschandl, Jochen Weber, Veronica Rotemberg, H Peter Soyer","doi":"10.1111/jdv.20479","DOIUrl":"https://doi.org/10.1111/jdv.20479","url":null,"abstract":"<p><strong>Background: </strong>While the high accuracy of reported AI tools for melanoma detection is promising, the lack of holistic consideration of the patient is often criticized. Along with medical history, a dermatologist would also consider intra-patient nevi patterns, such that nevi that are different from others on a given patient are treated with suspicion.</p><p><strong>Objective: </strong>To evaluate whether patient-contextual lesion-images improves diagnostic accuracy for melanoma in a dermoscopic image-based AI competition and a human reader study.</p><p><strong>Methods: </strong>An international online AI competition was held in 2020. The task was to classify dermoscopy images as melanoma or benign lesions. A multi-source dataset of dermoscopy images grouped by patient were provided, and additional use of public datasets was permitted. Competitors were judged on area under the receiver operating characteristic (AUROC) on a private leaderboard. Concurrently, a human reader study was hosted using a subset of the test data. Participants gave their initial diagnosis of an index case (melanoma vs. benign) and were then presented with seven additional lesion-images of that patient before giving a second prediction of the index case. Outcome measures were sensitivity and specificity.</p><p><strong>Results: </strong>The top 50 of 3308 AI competition entries achieved AUROC scores ranging from 0.943 to 0.949. Few algorithms considered intra-patient lesion patterns and instead most evaluated images independently. The median sensitivity and specificity of human readers before receiving contextual images were 60.0% and 86.7%, and after were 60.0% and 85.7%. Human and AI algorithm performance varied by image source.</p><p><strong>Conclusion: </strong>This study provided an open-source state-of-the-art algorithm for melanoma detection that has been evaluated at multiple centres. Patient-contextual images did not positively impact performance of AI algorithms or human readers. Providing seven contextual images and no total body image may have been insufficient to test the applicability of the intra-patient lesion patterns.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samantha Keow, Bonnie Lu, Dea Metko, Mohannad Abu-Hilal
{"title":"Merkel cell carcinoma after solid organ transplant.","authors":"Samantha Keow, Bonnie Lu, Dea Metko, Mohannad Abu-Hilal","doi":"10.1111/jdv.20481","DOIUrl":"https://doi.org/10.1111/jdv.20481","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Upadacitinib for orofacial granulomatosis associated with Crohn's disease.","authors":"Gaëlle Colin, Manon Girod, Emilie Malezieux, Romain Altwegg, Céline Girard","doi":"10.1111/jdv.20486","DOIUrl":"https://doi.org/10.1111/jdv.20486","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of olaparib combined with dabrafenib and trametinib for a patient with BRAF mutated and ATM deleted metastatic melanoma.","authors":"Theo Marguet, Stéphane Mouret, Aude Belbézier, Camila Castillo-Ferrer, Lucie Sancey, Pauline Porret, Isabelle Templier, Amandine Hurbin, Véronique Frachet, Mona Amini-Adle, Nausicaa Malissen, Julie Charles","doi":"10.1111/jdv.20483","DOIUrl":"https://doi.org/10.1111/jdv.20483","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ellen Van den Steen, Diederik De Cock, Jo Lydie Wilfried Lambert, Valerie Reynaert, Kilian Eyerich, Branka Marinović, Jan Gutermuth
{"title":"Experience of patients and healthcare practitioners with interdisciplinary care in immune-mediated inflammatory diseases with skin manifestations: A systematic scoping review.","authors":"Ellen Van den Steen, Diederik De Cock, Jo Lydie Wilfried Lambert, Valerie Reynaert, Kilian Eyerich, Branka Marinović, Jan Gutermuth","doi":"10.1111/jdv.20449","DOIUrl":"https://doi.org/10.1111/jdv.20449","url":null,"abstract":"<p><p>Immune-mediated inflammatory diseases with skin manifestations (skIMIDs) may affect multiple organs. Interdisciplinary care (IC) can overcome the fragmented knowledge used in the management of skIMIDs. In skIMIDs-care, patient and healthcare practitioner (HCP) satisfaction with IC is unknown. Yet, patient experience influences adherence and medical outcomes. Moreover, HCP experience influences professional satisfaction, perception of care quality and autonomy. Thus, measuring patient and HCP experience can identify areas for improvement in care delivery. The aim of this scoping review was to gather evidence on patient- and HCP perceptions on skIMID-IC and their measurement. We systematically searched on 30 August 2023 PubMed/EMBASE/Cinahl/Web of Science. Eligible studies had to address explicitly experience of IC by patients or HCPs. A conceptional synthesis appraised how experiences were measured and IC was perceived by patients and HCPs. The database search resulted in 21 eligible studies. Fourteen described positive patient and HCP experiences with a specific IC programme. These studies were heterogenous on the levels of IC models, medical conditions, measurement methods and outcomes. Despite that patients and HCPs rated such tailored IC models positively, seven studies on a geographically broader region reported less satisfaction with IC. A conceptual analysis identified domains deemed as important regarding IC: 'general satisfaction', 'patient-HCP interaction', 'information', 'functioning of IC', 'benefits of IC'. For patients, 'access to care' and 'disease management' were added. For HCPs 'illness perception' was deemed relevant. The heterogeneous way in how IC experience is captured hinders strong conclusions, which mandates the development of standardized analysis tools. Experience with IC in skIMIDs strongly depends on the context of the provided IC and patient experience seems to be better in local IC programmes than systems rolled out in larger geographical regions. Future need is to develop a core IC outcome set including medical outcomes, process indicators, financial indicators, plus patient and HCP care experience measures.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142791711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond the scoreboard: Coaches' UV-related skin cancer knowledge in outdoor sports.","authors":"Sven Schneider, Zoe A Parsons, Sophie Leer","doi":"10.1111/jdv.20461","DOIUrl":"https://doi.org/10.1111/jdv.20461","url":null,"abstract":"<p><strong>Background: </strong>The global rise in UV radiation is widely recognized as one of the most relevant health impacts of climate change. Consequently, the prevalence of skin cancer is experiencing a significant increase, with outdoor athletes being identified as a particularly vulnerable population group.</p><p><strong>Objectives: </strong>This study aims to investigate the extent of UV-specific skin cancer knowledge among coaches in outdoor sports and to examine potential variations in this knowledge between different sports, coach- and club-specific factors.</p><p><strong>Methods: </strong>This nationwide representative study was conducted among outdoor sports coaches from the 10 largest outdoor sports associations in Germany. Their knowledge of the risks associated with UV radiation and prevention measures were evaluated using the Skin Cancer and Sun Knowledge Scale (SCSK Scale).</p><p><strong>Results: </strong>Out of 1200 participating trainers, the UV-specific skin cancer knowledge score averaged 17.76 (±2.98) on a scale ranging from 0 to 25. The true-false statements 'A tan is a sign that the skin is damaged' (true) and 'When using sunscreen, you can tan without any negative effects' (false) were most frequently answered incorrectly. Only 16% of participants correctly identified basal cell carcinoma as the most prevalent form of skin cancer. Differences in UV-specific skin cancer knowledge were evident across different sports, with football and tennis coaches showing the major knowledge deficits. Conversely, trainers in skiing, swimming and mountain sports demonstrated the highest levels of knowledge. Significant deficiencies in knowledge were particularly notable among male trainers, as well as those from the youngest and the oldest age group, with limited training experience and who primarily worked with children and adolescents in small clubs on a regular basis.</p><p><strong>Conclusions: </strong>Serious knowledge deficiencies are evident among German outdoor sports coaches. The study results emphasize the necessity for enhanced coach education and the implementation of evaluated concepts for climate adaptation in sports.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ji Su Lee, Byeol Han, Hoonjae Lee, Daejeong Moon, Daeseon Kim, Terry TaeWoong Um, Soo Ick Cho, Jung-Im Na
{"title":"Robustness of automated acne lesion detection across various imaging conditions: A comparative analysis with dermatologists.","authors":"Ji Su Lee, Byeol Han, Hoonjae Lee, Daejeong Moon, Daeseon Kim, Terry TaeWoong Um, Soo Ick Cho, Jung-Im Na","doi":"10.1111/jdv.20471","DOIUrl":"https://doi.org/10.1111/jdv.20471","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bimatoprost for the management of vitiligo: A systematic review and meta-analysis.","authors":"Aliyah King, Siddhartha Sood, Monica K Li","doi":"10.1111/jdv.20458","DOIUrl":"https://doi.org/10.1111/jdv.20458","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hamza Malick, Mojahed Mohammad K Shalabi, Seo Won Cho, Aaisha Firdaus, Kyle C Lauck, Stanislav N Tolkachjov
{"title":"Increased rates of complications in diabetic patients undergoing Mohs micrographic surgery: An international, propensity-matched, retrospective cohort study.","authors":"Hamza Malick, Mojahed Mohammad K Shalabi, Seo Won Cho, Aaisha Firdaus, Kyle C Lauck, Stanislav N Tolkachjov","doi":"10.1111/jdv.20470","DOIUrl":"https://doi.org/10.1111/jdv.20470","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142770245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Probing into functional decline among bullous pemphigoid patients.","authors":"Wei-Zhen Tang, Kang-Jin Huang, Tai-Hang Liu","doi":"10.1111/jdv.20469","DOIUrl":"https://doi.org/10.1111/jdv.20469","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}