Journal of the European Academy of Dermatology and Venereology最新文献

{"title":"Fibrosis quantification in hidradenitis suppurativa tunnels: Histological correlation with shear wave elastography.","authors":"Laura Mateu-Arrom, Anna Mozos, Lluis Puig, Eva Vilarrasa","doi":"10.1111/jdv.20514","DOIUrl":"https://doi.org/10.1111/jdv.20514","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Napoleon's skin disease and treatment be identified from paleoproteomic analyses of his last bathtub (1821)?","authors":"Philippe Charlier, Jean Armengaud, Joel Poupon, Saudamini Deo, Alain Astier","doi":"10.1111/jdv.20517","DOIUrl":"https://doi.org/10.1111/jdv.20517","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discovering basal cell carcinoma cellular origin via reflectance confocal microscopy.","authors":"Luca Ambrosio, Vincenzo Roberti, Pablo Uribe, Camilla Chello, Miguel Villaseca, Cristian Navarrete-Dechent, Chiara Retrosi, Claudio Conforti, Giovanni Pellacani","doi":"10.1111/jdv.20507","DOIUrl":"https://doi.org/10.1111/jdv.20507","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment.","authors":"C C Zouboulis, F G Bechara, F Benhadou, V Bettoli, Z Bukvić Mokos, V Del Marmol, M Dolenc-Voljč, E J Giamarellos-Bourboulis, Ø Grimstad, P Guillem, B Horváth, R E Hunger, J R Ingram, D Ioannidis, E Just, L Kemény, B Kirby, A I Liakou, B M McGrath, A V Marzano, Ł Matusiak, A Molina-Leyva, A Nassif, M Podda, E P Prens, F Prignano, H Raynal, M Romanelli, D M L Saunte, A Szegedi, J C Szepietowski, T Tzellos, S Valiukevičienė, H H van der Zee, K R van Straalen, B Villumsen, G B E Jemec","doi":"10.1111/jdv.20472","DOIUrl":"https://doi.org/10.1111/jdv.20472","url":null,"abstract":"<p><strong>Introduction: </strong>This second part of the S2k guidelines is an update of the 2015 S1 European guidelines.</p><p><strong>Objective: </strong>These guidelines aim to provide an accepted decision aid for the selection, implementation and assessment of appropriate and sufficient therapy for patients with hidradenitis suppurativa/acne inversa (HS).</p><p><strong>Methods: </strong>The chapters have been selected after a Delphi procedure among the experts/authors. Certain passages have been adopted without changes from the previous version. Potential treatment complications are not included, being beyond the scope of these guidelines.</p><p><strong>Results: </strong>Since the S1 guidelines publication, validation of new therapeutic approaches has almost completely overhauled the knowledge in the field of HS treatment. Inflammatory nodules/abscesses/draining tunnels are the primary lesions, which enable the classification of the disease severity by new validated tools. In relation to the degree of detectable inflammation, HS is classified into the inflammatory and the predominantly non-inflammatory forms. While the intensity of the inflammatory form can be subdivided by the IHS4 classification in mild, moderate and severe HS and is treated by medication accordingly, the decision on surgical treatment of the predominantly non-inflammatory form is based on the Hurley stage of the affected localization. The effectiveness of oral tetracyclines as an alternative to the oral combination of clindamycin/rifampicin should be noted. The duration of systemic antibiotic therapy can be shortened by a 5-day intravenous clindamycin treatment. Adalimumab, secukinumab and bimekizumab subcutaneous administration has been approved by the EMA for the treatment of moderate-to-severe HS. Various surgical procedures are available for the predominantly non-inflammatory form of the disease. The combination of a medical therapy to reduce inflammation with a surgical procedure to remove irreversible tissue damage is currently considered a holistic therapeutic approach.</p><p><strong>Conclusions: </strong>Suitable therapeutic options while considering HS severity in the therapeutic algorithm according to standardized criteria are aimed at ensuring a proper therapy.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Certolizumab pegol for plaque psoriasis in women of childbearing potential, pregnant or breastfeeding in clinical settings: One-year outcomes from the international noninterventional CIMREAL study.","authors":"Hillary Tom, Lovegrove Fiona, Boye Thierry, Papadavid Evangelia, Bianchi Luca, Flórez Ángeles, Barea Alberto, Fierens Frederik, D Pousa Ines, Jackie Hee, Paulette Williams, Asadullah Khusru","doi":"10.1111/jdv.20516","DOIUrl":"https://doi.org/10.1111/jdv.20516","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating oral roflumilast in patients with hidradenitis suppurativa previously exposed to biologic treatment.","authors":"Nikolaj Holgersen, Valdemar Wendelboe Nielsen, Hans Christian Ring, Alexander Egeberg, Jacob P Thyssen, Mette Gyldenløve, Simon Francis Thomsen","doi":"10.1111/jdv.20515","DOIUrl":"https://doi.org/10.1111/jdv.20515","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced cardiovascular risks in patients with porphyria Cutanea Tarda: A retrospective cohort study.","authors":"Madelyn L Schmidt, Lynchi Nguyen, Casey Brusen, Elise Weisert, Anthony Linfante","doi":"10.1111/jdv.20509","DOIUrl":"https://doi.org/10.1111/jdv.20509","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lentigo maligna: A retrospective analysis of 50 cases treated with imiquimod monitored with non-invasive reflectance confocal microscopy.","authors":"Navreet Paul, Kamalini Lecamwasam, May Fadhil, Jennifer Garioch","doi":"10.1111/jdv.20505","DOIUrl":"https://doi.org/10.1111/jdv.20505","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Line-field confocal optical coherence tomography coupled with artificial intelligence algorithms as tool to investigate wound healing: A prospective, randomized, single-blinded pilot study.","authors":"Sergio Del Río-Sancho, Stephanie Christen-Zaech, David Alvarez Martinez, Jöri Pünchera, Stéphane Guerrier, Hans J Laubach","doi":"10.1111/jdv.20478","DOIUrl":"https://doi.org/10.1111/jdv.20478","url":null,"abstract":"<p><strong>Background: </strong>Ablative fractional photothermolysis serves as an excellent in vivo model for studying wound healing. The advent of non-invasive imaging devices, such as line-field confocal optical coherence tomography (LC-OCT), enhances this model by enabling detailed monitoring of skin wound healing over time. Additionally, artificial intelligence (AI)-based algorithms are revolutionizing the evaluation of clinical images by providing detailed analyses that are unfeasible manually.</p><p><strong>Objectives: </strong>This study aims to assess the value of combining LC-OCT and AI for evaluating the acute wound healing process in the skin.</p><p><strong>Methods: </strong>The forearms of participating volunteers were ablated with a CO₂ laser in a fractional pattern (7.5 mJ/MTZ) (ClinicalTrials.gov identifier: NCT05614557). To induce observable wound healing differences, two different approved silicone-based formulations were randomly assigned to two test sites, with a third site left untreated. In vivo LC-OCT images were obtained at predefined intervals post-laser treatment, ranging from 1 to 7 days. These images were further analysed using AI algorithms.</p><p><strong>Results: </strong>LC-OCT visualization allows for the characterization of the structural reorganization of the skin during wound healing. The additional integration of AI algorithms significantly enhances the evaluation of the efficacy of wound care interventions by providing a deeper understanding of how these interventions improve wound healing. This is particularly valuable for primary care providers and dermatologists, as AI algorithms have proven useful in observing, characterizing and understanding keratinocyte behaviour.</p><p><strong>Conclusions: </strong>The combination of AI and high-resolution imaging represents a promising tool for better understanding wound healing, evaluating the efficacy of current wound care interventions and analysing keratinocyte behaviour in detail during the wound healing process.</p><p><strong>Clinicaltrials: </strong></p><p><strong>Gov identifier: </strong>NCT05614557.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Napkin psoriasis and the risk of later psoriasis development: A single-centre retrospective study.","authors":"Iria Neri, Miriam Leuzzi, Martina Mussi, Federico Bardazzi, Alessandro Pileri, Bianca Maria Piraccini, Corrado Zengarini","doi":"10.1111/jdv.20513","DOIUrl":"https://doi.org/10.1111/jdv.20513","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}