Journal of the European Academy of Dermatology and Venereology最新文献

{"title":"Sublingual Minoxidil 5 mg versus Oral Minoxidil 5 mg for male androgenetic alopecia: A double-blind randomized clinical trial.","authors":"Baltazar Sanabria, Hélio Amante Miot, Rodney Sinclair, Christine Chaves, Paulo Müller Ramos","doi":"10.1111/jdv.20508","DOIUrl":"https://doi.org/10.1111/jdv.20508","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Baseline dermoscopic patterns predict long-term changes in nevus diameter and in dermoscopic features.","authors":"Ofer Reiter, Tomer Mimouni, Alon Scope, Nicholas R Kurtansky, Larissa Pastore, Allan C Halpern, Ashfaq A Marghoob","doi":"10.1111/jdv.20503","DOIUrl":"https://doi.org/10.1111/jdv.20503","url":null,"abstract":"<p><strong>Background: </strong>When monitoring melanocytic neoplasms, the pattern of change may distinguish nevi from melanoma. Anticipating the growth dynamics of nevi based on their dermoscopic pattern is important to make this distinction.</p><p><strong>Objective: </strong>The primary aim was to examine the association between nevus dermoscopic pattern at baseline and diameter change during long-term monitoring. The secondary aim was to examine the association between nevus dermoscopic pattern at baseline and changes in both dermoscopic pattern and colour during long-term monitoring.</p><p><strong>Methods: </strong>The study included high-risk adult patients that underwent ≥2 total-body photography (TBP) sessions, with at least 14 years' time gap between first and last sessions. Nevi on the torso, with available dermoscopic images, were included. New and disappearing nevi were defined as nevi not appearing on the first and last TBP, respectively. Nevus diameter and colour were assessed on clinical images of first and last TBP images. Dermoscopic images were analysed for dermoscopic patterns and structures at baseline and follow-up.</p><p><strong>Results: </strong>In total, 877 nevi from 101 patients were included. Mean follow-up time between TBPs and between dermoscopic images was 16.7 and 11.5 years, respectively. Most nevi were reticular or structureless at baseline, but new nevi had a higher frequency of peripheral globules and smudgy patterns. Peripheral globules and diffuse negative network patterns as well as regression structures were associated with nevus diameter growth. In total, 30% and 15% of new and existing nevi, respectively, demonstrated dermoscopic pattern change, mainly transforming into reticular and structureless patterns.</p><p><strong>Conclusions: </strong>Among high-risk patients, nevi showing peripheral globules or negative network are more likely to grow in diameter during long-term monitoring. Most nevi retain their overall dermoscopic pattern and those that change, mostly transform into reticular or structureless patterns.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spesolimab in refractory paediatric acrodermatitis continua of Hallopeau, a case series.","authors":"Liting Cai, Yunling Yan, Yang Li, Junjie Lin, Xinyan She, Xiaohua Wang","doi":"10.1111/jdv.20500","DOIUrl":"https://doi.org/10.1111/jdv.20500","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness, safety and reasons for discontinuation of sonidegib for patients with locally advanced basal cell carcinoma: A real-word evidence analysis from the French national registry CARADERM.","authors":"Nicole Basset-Seguin, Mourad Djermane, Florian Herms, Sophie Dalac, Olivier Dereure, Marie Beylot-Barry, Mona Amini-Adle, Benoît Minart, Florence Granel-Brocard, Nicolas Meyer, Thomas Jouary, Brigitte Dreno, Laurent Mortier","doi":"10.1111/jdv.20496","DOIUrl":"https://doi.org/10.1111/jdv.20496","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dapagliflozin-associated chronic balanitis due to Streptococcus agalactiae.","authors":"Caroline Donzel, Romain Salle, Jean-David Bouaziz, Sébastien Fouéré, Tu-Anh Duong, Jean-Noël Dauendorffer","doi":"10.1111/jdv.20510","DOIUrl":"https://doi.org/10.1111/jdv.20510","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142823939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health care pathways for patients with epidermolysis bullosa: A position statement from the European reference network for rare skin diseases.","authors":"S Krämer, A L Hillebrecht, K Bekes, K Bücher, V Clark, H Haririan, J Jakowski, C Joseph, N Meißner, J Monteiro, S Porter, R Schilke, S Veliz, V Verhaeghe, A Vinereanu, M C Bolling, A Diem, J E Mellerio, C Bodemer, C Has","doi":"10.1111/jdv.20498","DOIUrl":"https://doi.org/10.1111/jdv.20498","url":null,"abstract":"<p><strong>Background: </strong>Inherited epidermolysis bullosa (EB) comprises a group of genetic disorders characterized by skin fragility and unique oral features. It requires interdisciplinary care from several health professionals, including oral health teams. Modern dentistry encompasses a wide range of therapeutic options performed by specialists from different fields.</p><p><strong>Objective: </strong>To guide clinicians caring for patients with different types of EB to seek care from different dental services.</p><p><strong>Methods: </strong>Dental treatment needs for patients with EB were identified based on a systematic literature review. A panel of experts was consulted and invited to provide additional information through an open-ended question over 7 months. A Delphi study was applied over two rounds to the resulting pathways design. The threshold of consensus was set a priori at 75%. Patients' representatives revised the final document.</p><p><strong>Results: </strong>The panel (n = 17) agreed on a total of 55 recommendations divided into six groups according to the severity of oral compromise in EB (52 recommendations were agreed on in round 1, and three were agreed on in round 2).</p><p><strong>Conclusions: </strong>Dental care pathways are presented for each type of EB. Specific considerations are discussed according to clinical features, including age of first referral, frequency of follow-up appointments, and list of dental specialties involved in the care of patients with EB.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and treatment of Adamantiades-Behçet's disease in Germany: A healthcare claims database study.","authors":"C C Zouboulis, J Borchert, J Diesing, R Heinrich, W Galetzka, J-P Medelnik, A Altenburg, A Feldhus, T Schönfelder","doi":"10.1111/jdv.20489","DOIUrl":"https://doi.org/10.1111/jdv.20489","url":null,"abstract":"<p><strong>Background: </strong>Adamantiades-Behçet's disease (ABD) is a rare, chronic, relapsing, multisystem vasculitis, with a reported prevalence of 0.9 out of 100,000 population in Germany in 2012. However, more recent epidemiological data are lacking.</p><p><strong>Objectives: </strong>To estimate the prevalence and incidence of ABD in Germany and assess associated comorbidities and current treatment patterns.</p><p><strong>Methods: </strong>This retrospective cohort study used claims data from the anonymized Institute for Applied Health Research Berlin (InGef) research database. Cohorts were formed for the observation years 2016, 2017 and 2018, using data from 2013 to 2018 (allowing for a 3-year baseline period for incidence data). The study population included patients ≥18 years old with a diagnosis of ABD (ICD-10 diagnostic code M35.2), covered under the statutory health insurance system and in the InGef research database, with continuous insurance in the observation year and baseline period. We descriptively evaluated prevalence (≥2 outpatient ABD diagnoses in different quarters/≥1 main inpatient diagnosis in the observation year), incidence (no confirmed outpatient/inpatient diagnosis in the baseline period), comorbidities reported during the study and ABD-related medications.</p><p><strong>Results: </strong>We identified 300, 303 and 329 patients diagnosed with ABD in 2016, 2017 and 2018, respectively, with fewer than half (122/300 [40.7%], 127/303 [41.9%] and 150/329 [45.6%]) prescribed ≥1 disease-related medication. In the treated population, ABD prevalence was 3.9 (2016), 4.1 (2017) and 4.7 (2018) per 100,000 population; annual ABD incidence was 0.5 per 100,000 population in 2016 and 2017 and 0.6 per 100,000 population in 2018. The most commonly reported comorbidities in patients diagnosed with ABD were dorsalgia (an indicator of possible misdiagnosis), disorders of refraction and accommodation, and essential (primary) hypertension. Prednisolone, colchicine and azathioprine were the most commonly prescribed treatments for ABD, with approximately 15% of patients taking >1 medication for ABD.</p><p><strong>Conclusions: </strong>The reported data provide evidence that ABD remains a rare disease in Germany.</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infections and genotypes of Chlamydia trachomatis among men who have sex with men in China: A nationwide community-based study.","authors":"Ting-Ting Jiang, Ning-Xiao Cao, Wan-Yue Zhang, Xing-Dong Ye, Yu-Mao Cai, Min-Zhi Wu, Ai-Li Li, Zhan-Feng Han, Yi Zheng, Hai-Bo Ding, Li-Qin Gu, Hong-Chun Liao, Li Yan, Quan Luo, Yun-Qing Yang, Mei-Qin Shi, Yan Han, Yue-Ping Yin, Xiang-Sheng Chen","doi":"10.1111/jdv.20487","DOIUrl":"https://doi.org/10.1111/jdv.20487","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term follow-up of a randomized, double-blind, phase III, multi-centre study to evaluate the safety and efficacy of field-directed photodynamic therapy (PDT) of mild to moderate actinic keratosis using BF-200 ALA versus placebo and the BF-RhodoLED® lamp.","authors":"U Reinhold, W G Philipp-Dormston, T Dirschka, R Ostendorf, R Aschoff, C Berking, A Jäger, B Schmitz, M Foguet, R-M Szeimies","doi":"10.1111/jdv.20452","DOIUrl":"https://doi.org/10.1111/jdv.20452","url":null,"abstract":"<p><strong>Background: </strong>In actinic keratosis (AK), field cancerization describes areas of skin where multiple visible AK lesions are surrounded by healthy looking skin containing non-visible (subclinical) lesions. As all AK lesions have a risk of progression to cutaneous squamous cell carcinoma, experts advise field-directed treatment. Photodynamic therapy (PDT) is an effective field-directed treatment option for AK; however, long-term efficacy data are still scarce.</p><p><strong>Objectives: </strong>This publication presents follow-up data of a phase III study evaluating the efficacy and safety of field-directed PDT.</p><p><strong>Methods: </strong>The study was conducted in seven centres in Germany. For PDT, participants with AKs on the face and scalp (treatment area of 20 cm²) had received up to two field-directed PDTs using BF-200 ALA or placebo, and illumination with narrow-spectrum red light. Only participants or lesions with complete response 12 weeks after the last PDT were assessed for recurrences. The treatment area was evaluated 6 and 12 months after the last PDT for recurrence, cosmetic outcome and new lesions.</p><p><strong>Results: </strong>Fifty-four participants in the BF-200 ALA and 30 in the placebo group entered the follow-up. The probability of a participant to be initially completely cleared and to remain cleared for 12 months was 57.4% for BF-200 ALA versus 20.0% for placebo. The probability of a lesion to be initially cleared and remain cleared for 12 months was 85.4% for BF-200 ALA versus 31.5% for placebo. 83.3% of participants with cosmetic impairment at baseline rated the cosmetic outcome 12 months after PDT with BF-200 ALA as very good or good. All parameters of skin quality further improved during follow-up.</p><p><strong>Conclusions: </strong>We showed that effectiveness of field-directed PDT with BF-200 ALA and narrow-spectrum red light was maintained during follow-up. Based on our results, field-directed PDT is a beneficial long-lasting treatment for AK patients.</p><p><strong>Clinical trial registration numbers: </strong>2013-002510-12 (EudraCT); NCT01966120 (Clinicaltrials.gov).</p>","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term real costs of a strategy using rituximab as first-line treatment for patients with moderate-to-severe pemphigus: Evaluation from the French healthcare system.","authors":"Billal Tedbirt, Hermance De Mulder, Pascal Joly, Elie Lacroix, Vivien Hébert","doi":"10.1111/jdv.20497","DOIUrl":"https://doi.org/10.1111/jdv.20497","url":null,"abstract":"","PeriodicalId":17351,"journal":{"name":"Journal of the European Academy of Dermatology and Venereology","volume":" ","pages":""},"PeriodicalIF":8.4,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142818520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}