Journal of the International Association of Providers of AIDS Care最新文献

{"title":"Feasibility and Implementation Considerations for Long-Acting Antiretroviral Therapy in Pakistan: A Qualitative Study of Healthcare Providers and Programmatic Stakeholders.","authors":"Muhammad Wasay Shahid, Faizur Rehman, Mehran Riaz, Muhammad Aaqib Akram, Farah Azhar, Malik Muhammad Umair, Nasim Akhtar, Musarat Jabeen, Ali Ahmed","doi":"10.1177/23259582261452317","DOIUrl":"10.1177/23259582261452317","url":null,"abstract":"<p><p>IntroductionLong-acting injectable antiretroviral therapy (LAI-ART), especially cabotegravir plus rilpivirine, is primarily recommended as a switch option for virally suppressed individuals and may improve adherence, privacy, and treatment satisfaction. Contemporary international guidance notes a restricted, closely monitored role for selected viraemic patients with persistent adherence challenges. Feasibility in low-resource systems remains uncertain. We explored perceived feasibility and acceptability of LAI-ART among HIV care providers and regulatory stakeholders in Pakistan.MethodsWe conducted semistructured in-depth interviews with 17 providers and stakeholders from ART centers, tertiary hospitals, the National AIDS Control Program, and a community-based organization in Islamabad and Rawalpindi. Interviews were audio recorded, transcribed, translated, and analyzed using reflexive thematic analysis.ResultsParticipants viewed LAI-ART as promising for improving adherence, treatment fatigue, confidentiality, and workflow. Barriers included travel distance, needle phobia, missed dose risks, staffing constraints, cold chain and storage needs, infrastructure limitations, and weak biomedical waste management.ConclusionStakeholders expressed cautious interest in LAI-ART while highlighting significant structural, financial, and sociocultural barriers. Participants emphasized that phased pilot implementation, sustainable financing, cultural acceptability, integration into differentiated service delivery, and stronger counselling and digital support would be necessary to support future introduction.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261452317"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13527321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147973376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patients' Positive Experiences and the Role of Agency and Respect in Supporting HIV Treatment and Care Outcomes Among Women Living With HIV: Implications for Trauma- and Violence-Informed HIV Care and Practice From a Longitudinal Cohort Study.","authors":"Kathleen N Deering, Desire King, Colleen Thompson, Haoxuan Zhou, Kate Shannon","doi":"10.1177/23259582261447934","DOIUrl":"10.1177/23259582261447934","url":null,"abstract":"<p><p>ObjectiveWe examined the association between 18 covariates measuring women's self-reported positive experiences with their main HIV care provider/clinics, drawing on the Substance Abuse and Mental Health Services Administration \"trauma-informed care\" framework, and multiple HIV treatment/care outcomes.MethodsData (2014-2021) were drawn from a longitudinal community-based cohort with women living with HIV in Metro Vancouver (the Sexual Health and HIV/AIDS: Longitudinal Women's Needs Assessment) and analyzed using multivariable logistic regression with generalized estimating equations.ResultsMultivariable analysis suggested that principles of \"<i>safety and respect\"</i> (eg, feeling safe discussing sexual and/or reproductive health, confidentiality) and \"<i>strength-based collaboration\"</i> (eg, agency in scheduling, actively participating in one's own care) were significantly associated with higher odds of optimal HIV treatment/care outcomes.ConclusionsOur study provides evidence for the benefit of incorporating and scaling up education, training and health systems policies that support women's positive experiences with their main HIV care provider/clinics in a trauma- and violence-informed framework.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261447934"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148302191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telehealth-Enabled Rapid Antiretroviral Restart for People With HIV Out of Care (ACCELERATE): A Mixed-Methods Study of Staff Perspectives.","authors":"Kristine Allen-Brown, Rami Rifi, Rachael Hernandez, Hilal Abdessamad, Thomas Deem, Wassim Jamaleddine, Ghinwa Al Hassanieh, Blair Thedinger, Dima Dandachi","doi":"10.1177/23259582261494722","DOIUrl":"https://doi.org/10.1177/23259582261494722","url":null,"abstract":"<p><p>IntroductionACCELERATE is a multisite Type II hybrid effectiveness-implementation mixed-methods study evaluating a rapid antiretroviral therapy (ART) restart model for people with HIV (PWH) out of care (OOC). We assessed staff and provider perspectives on implementation.MethodsHealthcare providers and staff at three Missouri sites completed surveys at baseline and Week 48 (W48) assessing implementation outcomes, job satisfaction, burnout, and telehealth perceptions. Semi-structured interviews were analyzed using a convergent mixed-methods design.ResultsThirty-one participants completed baseline surveys and 15 completed W48 surveys. Acceptability, feasibility, and appropriateness remained high (baseline/W48: AIM 4.63/4.47, FIM 4.43/4.50, IAM 4.60/4.42). Job satisfaction remained high, though burnout-related items increased modestly. Providers reported increased agreement that telehealth benefits outweighed negatives (p<0.05). Fourteen interviews identified barriers including staffing, care coordination, and communication, while facilitators included telehealth visits, mailed medications, streamlined workflows, and multidisciplinary support.ConclusionsStaff perceived the ACCELERATE model favorably; additional staffing and infrastructure may improve sustainability.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261494722"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Literacy, Knowledge of HIV/AIDS, and Public Stigma Among General Citizens of Japan: An Online Cross-Sectional Survey.","authors":"Taisuke Togari, Yoji Inoue, Sakurako Abe","doi":"10.1177/23259582251414562","DOIUrl":"10.1177/23259582251414562","url":null,"abstract":"<p><p>BackgroundThis study aimed to examine how health literacy, knowledge of HIV/AIDS, and public stigma are associated with social distance toward people living with HIV/AIDS (PLWH), as a behavioral manifestation of stigma, among the general Japanese population.MethodsWe conducted an online cross-sectional survey targeting adults (age range: 20-60 s) from among the 2.2 million registrants in Rakuten Insight from September 20 to 25, 2019. Stratified randomized sampling was performed according to the region, sex, and age. The study participants were 2268 eligible for analysis (effective response rate: 90.7%).ResultsModels were examined using hierarchical multiple regression analysis. The results indicated that low-level knowledge of HIV/AIDS affected social distance to PLWH (B = 3.77, (95% CI, 1.30 to 6.24)). 'Access,' 'understand,' 'appraise' and 'use' of European health literacy survey questionnaire affected social distance to PLWH (B = .03, (-.07 to .13); - B = .15, (-.27 to -.04); B = .06, (-.04 to .17); B = -.07, (-.19 to .05)). Public stigma of HIV/AIDS affected social distance to PLWH (B = .97, (.92 to 1.01)).ConclusionsThese findings indicate that health literacy not only maintains and promotes individual health but also has the potential to reduce social distance toward PLWH.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582251414562"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12852594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146064372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes of Switching to Bictegravir/Emtricitabine/Tenofovir Alafenamide in People Living With HIV and Low-Level Viraemia.","authors":"Ignacio de Los Santos, Guillermo Pousada, Carlos Galera, Carlos Dueñas, Luis Buzón, José Sanz, Cristina Martín, María Ángeles Garcinuño, María José Galindo, Lucio García-Fraile, Roberto Pedrero-Tomé, Jesús Troya","doi":"10.1177/23259582261482031","DOIUrl":"10.1177/23259582261482031","url":null,"abstract":"<p><p>IntroductionLow-level viraemia (LLV) in people living with HIV (PLWH) remains a clinical challenge, associated with increased risk of virological failure, immune dysregulation, and chronic inflammation. Bictegravir/emtricitabine/tenofovir alafenamide is a single-tablet regimen with a high genetic barrier to resistance, but real-world outcomes after switching in PLWH with LLV remain insufficiently characterized. This study aimed to describe virological, immunological, metabolic, and safety outcomes after switching to bictegravir/emtricitabine/tenofovir alafenamide in PLWH with documented LLV over 96 weeks.MethodsA retrospective, multicentre study was conducted across 12 Spanish healthcare centres. PLWH aged ≥18 years with a documented qualifying LLV episode before switch (two consecutive HIV-1 RNA measurements between 50 and 400 copies/mL) who switched to bictegravir/emtricitabine/tenofovir alafenamide were included (N = 123). Outcomes included virological suppression (<50 copies/mL), residual LLV, CD4+/CD8+ dynamics, metabolic changes, and safety. Analyses were descriptive, used observed denominators, and included a non-completer=failure sensitivity analysis for virological suppression.ResultsAmong participants (median age: 52 years, 80.5% male; median time since HIV diagnosis: 30 years), observed LLV decreased to 11.4% (13/114 patients) at 96 weeks after switching to bictegravir/emtricitabine/tenofovir alafenamide (p<0.001). In the non-completer=failure sensitivity analysis, virological suppression at week 96 was 82.1% (101/123). At week 96, all detectable HIV-1 RNA values were 55-272 copies/mL; 3/13 patients had LLV at all available 24-, 48-, and 96-week visits. CD4+/CD8+ ratios remained stable, with a significant reduction in CD8+ T cell counts in patients ≥50 years. Biochemical markers were broadly stable, but weight/BMI increases and a shift toward overweight were observed and warrant monitoring. No treatment discontinuations due to adverse events were reported.ConclusionIn this single-arm retrospective cohort, switching to bictegravir/emtricitabine/tenofovir alafenamide was associated with a high observed proportion of virological suppression, immune stability, and favourable tolerability over 96 weeks; however, causal effectiveness cannot be inferred. These findings support further comparative prospective evaluation of bictegravir/emtricitabine/tenofovir alafenamide for LLV management.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261482031"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149182694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Diagnostic Value of Contrast-Enhanced MRI in Distinguishing Toxoplasmic Encephalitis from CNS Lymphoma: A Case Report of AIDS with Seronegative Toxoplasmosis.","authors":"Rinko Katsuda, Dai Watanabe, Yasuharu Nakahara, Yasuyuki Mizumori, Tetsuji Kawamura","doi":"10.1177/23259582251407370","DOIUrl":"10.1177/23259582251407370","url":null,"abstract":"<p><p>Toxoplasmic encephalitis (TE) and primary central nervous system (CNS) lymphoma are the major differential diagnoses of ring-enhanced brain lesions in acquired immunodeficiency syndrome (AIDS). Biopsy may be difficult; thus, empirical anti-toxoplasma therapy is often initiated. We report an AIDS patient receiving chemotherapy for Kaposi's sarcoma who developed TE. Weekly gadolinium-enhanced magnetic resonance imaging (MRI) demonstrated diminishment of ring enhancement 7 days after treatment, preceding neurological improvement and lesion size reduction. This early radiological change, captured by rare weekly gadolinium-enhanced MRI, was useful for differentiating TE from lymphoma before neurological improvement.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582251407370"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12816516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Complexities of Antiretroviral Treatment Adherence Among Adolescents and Young Adults in South Africa: Insights From a Scoping Review.","authors":"Bandile Ernest Ndlazi, David Ditaba Mphuthi","doi":"10.1177/23259582251411126","DOIUrl":"10.1177/23259582251411126","url":null,"abstract":"<p><p>Globally, the number of adolescents and young adults (AYAs) living with human immunodeficiency virus (HIV) has steadily increased; however, retaining them in antiretroviral treatment (ART) remains a challenge. This scoping review identifies and synthesizes research findings on ART adherence of AYAs living with HIV in South Africa. We conducted electronic searches across various databases and identified 20 peer-reviewed articles. Five key themes that characterize the research on ART adherence among AYAs living with HIV emerged. The themes include balancing healthcare and daily activities, desire for HIV status secrecy, psychosocial implications and knowledge of ART. Availability of support was found to enhance ART adherence. ART adherence barriers included treatment and healthcare-specific challenges requiring adjustments from facilities and AYAs. Enhancing ART adherence requires individuals' knowledge of ART and acceptance of their HIV status. The Healthcare system may need to be flexible to accommodate this group as they navigate between daily activities and ART adherence.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582251411126"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12949307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147290085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Music and Counseling Programs on Mental Health and Antiretroviral Treatment Adherence of Adolescents and Young Adults Living With HIV in Northern Thailand, a Randomized Trial.","authors":"Chintana Khamrong, Rattika Thammalangka, Kalunyu Kotchawat, Nakhon Khamrong, Linda Aurpibul, Jakkrit Klaphajone, Teerawan Teerapong, Natthapol Kosashunhanan","doi":"10.1177/23259582261439584","DOIUrl":"10.1177/23259582261439584","url":null,"abstract":"<p><p>BackgroundMental health significantly impacts antiretroviral treatment (ART) adherence in adolescents and young adults with perinatal HIV (AYA-PHIV), posing challenges for healthcare providers. This study investigated the effects of music and counseling programs on mental health and treatment adherence of AYA-PHIV.MethodsIn a randomized controlled study, the participants were assigned to the Music and Counseling Program (Arm 1), the Music Program (Arm 2), the Counseling Program (Arm 3), and a no-intervention group (Arm 4). Before and after 10 weekly sessions of a 90-minute study intervention, ART adherence and mental health questionnaires were completed.ResultsAfter the intervention, Arm 1 participants had a significantly increased median self-esteem score (17-25, <i>P</i> = .05). A significantly decrease in mean Thai-IHSS scores were observed in Arm 1 and 3 participants.ConclusionsThe study demonstrated that music and counseling programs improved self-esteem and reduced internalized HIV-related stigma in AYA-PHIV. Most participants reported better ART adherence and improved virologic outcomes.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261439584"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13058201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147628145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk of Cardiovascular Disease Among People Living With HIV With Immunological Nonresponse.","authors":"Chenlu Xu, Guoxiang Zheng, Liu Li, Dingyan Yan, Wenhui Zhang, Hu Wan, Jinchuan Shi, Jie Han, Jun Yan, Jianhua Yu, Zongxing Yang, Xin Luo","doi":"10.1177/23259582261470495","DOIUrl":"10.1177/23259582261470495","url":null,"abstract":"<p><p>BackgroundWe aimed to compare 10-year CVD risk and echocardiographic abnormalities between people living with HIV (PLWH) with immunological non-response (INR) and those with immunological response (IR), and to explore associated factors.MethodsThis cross-sectional study enrolled 260 PLWH with INR and 260 age- and gender-matched PLWH with IR as controls. All participants underwent echocardiography, and their CVD risk was assessed using the Framingham Risk Score (FRS).ResultsCompared to controls, the study group had significantly higher 10-year CVD risk (11.86% vs 9.51%, <i>P</i><0.05) and a greater prevalence of echocardiographic abnormalities (83.5% vs 74.2%, <i>P</i>=0.01). A longer treatment duration, larger waist circumference, prolonged prothrombin time, lower education level, and carotid plaque presence were all significantly associated with increased CVD risk. Within the study group, age and lower CD19+ levels correlated with a higher rate of echocardiographic abnormalities. An interaction between age and immune reconstitution status on CVD risk was observed (<i>P</i><0.001).ConclusionsPoor immune reconstitution is associated with increased CVD risk and subclinical cardiac abnormalities, particularly among older PLWH. These findings underscore the need for targeted cardiovascular screening in this vulnerable population.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261470495"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13462636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148712969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a Risk Prediction Nomogram for Virologic Failure Among Patients on First-Line ART After ONE-J Program Implementation in Northwest Ethiopia.","authors":"Bekalu Bewket, Etsubdink Dessalew Abawa, Zelalem Alamrew Anteneh","doi":"10.1177/23259582261428509","DOIUrl":"10.1177/23259582261428509","url":null,"abstract":"<p><p>IntroductionVirological failure is defined as a plasma viral load >1000 copies/mL on 2 consecutive tests after 3 months of adherence support and 6 months of ART. In Ethiopia, limited studies have developed risk prediction models, though such models are vital for guiding patient-specific interventions and improving HIV treatment outcomes.ObjectiveThis study aims to determine the incidence and prognostic factors of virologic failure among HIV patients on first-line HAART following the one-J program at Felege Hiwot Hospital, Northwest Ethiopia, in 2025.MethodsA retrospective cohort study was conducted using patient records from Felegehiwot Comprehensive Specialized Hospital. Data were analyzed with STATA 17 and R 4.5.0. Descriptive statistics and multivariable logistic regression (via LASSO-selected predictors) were applied to develop a simplified nomogram. Model performance was evaluated using discrimination, calibration, and decision curve analysis to assess clinical utility.ResultThe incidence of virologic failure was 20.2% (95% CI: 17.9-22.6). Key predictors included TB-HIV co-infection, INH prophylaxis, CPT, adverse drug reactions, disclosure, alcohol use, smoking, and CD4 level. The model showed good performance (AUC = 0.817; reduced AUC = 0.810), strong calibration (Brier = 0.117), and superior clinical benefit in decision curve analysis.ConclusionA nomogram integrating 8 predictors TB-HIV co-infection, INH prophylaxis, CPT, adverse drug reaction history, disclosure status, alcohol use, smoking status, and CD4 count showed excellent discrimination (AUC = 0.817) and good calibration, indicating strong potential for individualized risk prediction in HIV patient management.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"25 ","pages":"23259582261428509"},"PeriodicalIF":2.1,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12949785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147317444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}