Juan Pablo Sánchez Navarro, Gustavo Barriga Angulo, José Antonio Mata Marín, Mara Rodríguez Evaristo, Paola Edith Padilla Noguera, Jesús Enrique Gaytán Martínez
{"title":"墨西哥城一家男性艾滋病毒诊所的男同性恋者PWH中无症状性传播感染的高患病率。","authors":"Juan Pablo Sánchez Navarro, Gustavo Barriga Angulo, José Antonio Mata Marín, Mara Rodríguez Evaristo, Paola Edith Padilla Noguera, Jesús Enrique Gaytán Martínez","doi":"10.1177/23259582251321039","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>The incidence of sexually transmitted infections (STIs) remains high among men who have sex with men (MSM) living with human immunodeficiency virus (HIV) (PWH). This study determined the prevalence of asymptomatic STIs in MSM PWH attending an HIV clinic in Mexico City.</p><p><strong>Methods: </strong>This cross-sectional study (May 2022-November 2023) included self-questionnaires on STI-related behaviors and symptoms, urethral samples for multiplex polymerase chain reaction (PCR), and serological tests for syphilis, HBV, and HCV.</p><p><strong>Results: </strong>Among 261 patients, 56.7% were receiving antiretroviral therapy, 41.8% had suppressed HIV-1 viral load, and 26.1% tested positive for at least one STI in urethral PCR. The most prevalent microorganisms were <i>Ureaplasma urealyticum</i> (14.9%), <i>Mycoplasma hominis</i> (6.9%), <i>Mycoplasma genitalium</i> (4.2%), and <i>Chlamydia trachomatis</i> (3.1%). Multiple infections were identified in 5.3% of cases. Seroprevalence rates for syphilis, HBV, and HCV were 17.6%, 6.5%, and 3.1%, respectively. Current smoking and insertive anal sex were the only statistically significant associated factors.</p><p><strong>Conclusions: </strong>This study underscores the high frequency of asymptomatic STIs and the importance of regular screening.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"24 ","pages":"23259582251321039"},"PeriodicalIF":2.2000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863256/pdf/","citationCount":"0","resultStr":"{\"title\":\"High Prevalence of Asymptomatic STIs in MSM PWH in a Male HIV Clinic in Mexico City.\",\"authors\":\"Juan Pablo Sánchez Navarro, Gustavo Barriga Angulo, José Antonio Mata Marín, Mara Rodríguez Evaristo, Paola Edith Padilla Noguera, Jesús Enrique Gaytán Martínez\",\"doi\":\"10.1177/23259582251321039\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>The incidence of sexually transmitted infections (STIs) remains high among men who have sex with men (MSM) living with human immunodeficiency virus (HIV) (PWH). This study determined the prevalence of asymptomatic STIs in MSM PWH attending an HIV clinic in Mexico City.</p><p><strong>Methods: </strong>This cross-sectional study (May 2022-November 2023) included self-questionnaires on STI-related behaviors and symptoms, urethral samples for multiplex polymerase chain reaction (PCR), and serological tests for syphilis, HBV, and HCV.</p><p><strong>Results: </strong>Among 261 patients, 56.7% were receiving antiretroviral therapy, 41.8% had suppressed HIV-1 viral load, and 26.1% tested positive for at least one STI in urethral PCR. The most prevalent microorganisms were <i>Ureaplasma urealyticum</i> (14.9%), <i>Mycoplasma hominis</i> (6.9%), <i>Mycoplasma genitalium</i> (4.2%), and <i>Chlamydia trachomatis</i> (3.1%). Multiple infections were identified in 5.3% of cases. Seroprevalence rates for syphilis, HBV, and HCV were 17.6%, 6.5%, and 3.1%, respectively. Current smoking and insertive anal sex were the only statistically significant associated factors.</p><p><strong>Conclusions: </strong>This study underscores the high frequency of asymptomatic STIs and the importance of regular screening.</p>\",\"PeriodicalId\":17328,\"journal\":{\"name\":\"Journal of the International Association of Providers of AIDS Care\",\"volume\":\"24 \",\"pages\":\"23259582251321039\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863256/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the International Association of Providers of AIDS Care\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/23259582251321039\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the International Association of Providers of AIDS Care","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/23259582251321039","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
High Prevalence of Asymptomatic STIs in MSM PWH in a Male HIV Clinic in Mexico City.
Background: The incidence of sexually transmitted infections (STIs) remains high among men who have sex with men (MSM) living with human immunodeficiency virus (HIV) (PWH). This study determined the prevalence of asymptomatic STIs in MSM PWH attending an HIV clinic in Mexico City.
Methods: This cross-sectional study (May 2022-November 2023) included self-questionnaires on STI-related behaviors and symptoms, urethral samples for multiplex polymerase chain reaction (PCR), and serological tests for syphilis, HBV, and HCV.
Results: Among 261 patients, 56.7% were receiving antiretroviral therapy, 41.8% had suppressed HIV-1 viral load, and 26.1% tested positive for at least one STI in urethral PCR. The most prevalent microorganisms were Ureaplasma urealyticum (14.9%), Mycoplasma hominis (6.9%), Mycoplasma genitalium (4.2%), and Chlamydia trachomatis (3.1%). Multiple infections were identified in 5.3% of cases. Seroprevalence rates for syphilis, HBV, and HCV were 17.6%, 6.5%, and 3.1%, respectively. Current smoking and insertive anal sex were the only statistically significant associated factors.
Conclusions: This study underscores the high frequency of asymptomatic STIs and the importance of regular screening.
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