Ashley Winters, Bernadette Jakeman, Kelsea Gallegos Aragon, Zoe Kasten, Alexander Bos, Jeremy Snyder, Alexandra Herman
{"title":"Contraceptive Use and Missed Opportunities for Family Planning Discussions in Women Living with Human Immunodeficiency Virus at an HIV Clinic.","authors":"Ashley Winters, Bernadette Jakeman, Kelsea Gallegos Aragon, Zoe Kasten, Alexander Bos, Jeremy Snyder, Alexandra Herman","doi":"10.1177/23259582221144449","DOIUrl":"https://doi.org/10.1177/23259582221144449","url":null,"abstract":"<p><p>The objective of this study was to examine contraception use and family planning discussions (FPD) in female people living with HIV (PLWH). A retrospective cohort study was conducted. Female PLWH were included if they were 18-44 years and received care in 2019 at an HIV clinic. 74 patients met inclusion; mean age was 35 years, 53% were white. All patients were prescribed antiretroviral therapy. 48.6% of patients had documented FPD. 64.9% of patients were using contraception; sterilization was most common (41.7%). Only five patients had a contraindication to hormonal contraception. No differences in contraception use were observed based on age, race, HIV viral load, number of visits, or past pregnancies. However, patients with documented FPD were more likely to use contraception (OR 4.55; 95% CI 1.35-15.29). Routine FPD and contraception use in female PLWH were low. Rates of sterilization were high in female PLWH. Providing quality family planning services is critical to increase contraception use and selection of the most appropriate contraception form.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"21 ","pages":"23259582221144449"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/95/a9/10.1177_23259582221144449.PMC9772939.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10512261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. C. Pratt, S. Jeffcoat, Samantha V. Hill, E. Gill, L. Elopre, T. Simpson, R. Lanzi, L. Matthews
{"title":"“We Feel Like Everybody's Going to Judge us”: Black Adolescent Girls’ and Young Women's Perspectives on Barriers to and Opportunities for Improving Sexual Health Care, Including PrEP, in the Southern U.S","authors":"M. C. Pratt, S. Jeffcoat, Samantha V. Hill, E. Gill, L. Elopre, T. Simpson, R. Lanzi, L. Matthews","doi":"10.1177/23259582221107327","DOIUrl":"https://doi.org/10.1177/23259582221107327","url":null,"abstract":"Black adolescent girls and young women (AGYW) are disproportionately affected by HIV in the southern U.S.; however, PrEP prescriptions to Black AGYW remain scarce. We conducted in-depth interviews (IDIs) with Black AGYW ages 14-24 in Alabama to explore opportunities for and barriers to sexual health care including PrEP prescription. Twelve AGYW participated in IDIs with median age 20 (range 19-24). All reported condomless sex, 1-3 sexual partners in the past 3 months, and 6 reported prior STI. Themes included: 1) Stigma related to sex contributes to inadequate discussions with educators, healthcare providers, and parents about sexual health; 2) Intersecting stigmas around race and gender impact Black women's care-seeking behavior; 3) Many AGYW are aware of PrEP but don't perceive it as an option for them. Multifaceted interventions utilizing the perspectives, voices, and experiences of Black cisgender AGYW are needed to curb the HIV epidemic in Alabama and the U.S. South.","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49522487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Maggiolo, D. Valenti, Rodolfo Teocchi, L. Comí, E. Filippo, M. Rizzi
{"title":"Adherence to and Forgiveness of 3TC/DTG in a Real-World Cohort","authors":"F. Maggiolo, D. Valenti, Rodolfo Teocchi, L. Comí, E. Filippo, M. Rizzi","doi":"10.1177/23259582221101815","DOIUrl":"https://doi.org/10.1177/23259582221101815","url":null,"abstract":"Background: adherence and forgiveness are key factors for virologic success. We evaluated them for 3TC/DTG. Methods: pharmacy refills were used to calculate the proportion of days covered (PDC). Forgiveness was calculated as the achieved rate of HIV-RNA threshold by a given level of imperfect adherence. Results: 240 PLWH were included. The median follow-up was 819 days (IQR 450-1459) for a total of 681 person/years of follow-up. Adherence was very high with a median of 99% (IQR 95%-100%). Consequently, the virologic response was sustained with 83.8% of PLWH never exceeding a HIV RNA of 50 copies/ml and 95.8% of subjects with a steadily HIV-RNA < 200 copies/ml. A PDC lower than 80% was associated with a negative outcome irrespective of the HIV-RNA threshold considered. Conclusions: The extensive virologic efficacy of 3TC/DTG demonstrated both in clinical trials and real-world experiences seems to rely more on its friendliness than on its forgiveness.","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49605848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Dunn, B. Baugh, Nika Bejou, D. Luo, Jennifer Campbell, Sareh Seyedkazemi, David Anderson
{"title":"Low Incidence and Brief Duration of Gastrointestinal Adverse Events with Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (D/C/F/TAF) Over 96 Weeks: Post hoc Analyses of AMBER and EMERALD","authors":"K. Dunn, B. Baugh, Nika Bejou, D. Luo, Jennifer Campbell, Sareh Seyedkazemi, David Anderson","doi":"10.1177/23259582221088202","DOIUrl":"https://doi.org/10.1177/23259582221088202","url":null,"abstract":"Gastrointestinal intolerance has been associated with ritonavir-boosted protease inhibitors. This post hoc analysis evaluated gastrointestinal adverse events of interest (AEOIs; diarrhea, nausea, abdominal discomfort, flatulence [MedDRAv21]) through Wk96 among patients enrolled in the phase 3 AMBER (treatment-naïve) and EMERALD (virologically suppressed) studies of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg. 362 and 763 patients initiated D/C/F/TAF in AMBER and EMERALD, respectively. All D/C/F/TAF-related gastrointestinal AEOIs were grade 1/2 in severity; none were serious. Across studies, incidence of D/C/F/TAF-related diarrhea and nausea were each ≤5% in Wk1 (≤1% post-Wk2); prevalence of each decreased to <5% post-Wk2. In each study, there was 1 case of D/C/F/TAF-related abdominal discomfort during Wk1 and none thereafter. Incidence of D/C/F/TAF-related flatulence was <1% throughout. Median duration of D/C/F/TAF-related gastrointestinal AEOIs was 16.5 (AMBER) and 8.5 (EMERALD) days. In conclusion, in treatment-naïve and virologically suppressed patients, incidences and prevalences of D/C/F/TAF-related gastrointestinal AEOIs were low and tended to present early.","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42569996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Outcomes of Transition from Pediatrics to Adult Care among Adolescents and Young Adults with HIV at a Tertiary Care Center in Bangkok.","authors":"Supattra Rungmaitree, Nuchanat Thamniamdee, Saranya Sachdev, Wanatpreeya Phongsamart, Keswadee Lapphra, Orasri Wittawatmongkol, Alan Maleesatharn, Benjawan Khumcha, Risa M Hoffman, Kulkanya Chokephaibulkit","doi":"10.1177/23259582221143673","DOIUrl":"https://doi.org/10.1177/23259582221143673","url":null,"abstract":"<p><p><b>Background:</b> Adolescents and young adults with HIV (AYHIV) are at high-risk of loss to follow up and virologic failure, particularly during transition from pediatric to adult clinics. <b>Methods:</b> We reviewed the medical records of AYHIV to characterize retention and virologic suppression following their transition. <b>Results:</b> 101 AYHIV, 97% perinatally infected, were transferred at the median age of 20 (IQR: 19-21) years. At 1-year post-transition, 92.1% were retained in care and 73.3% had viral suppression and at 2-years the retention and viral suppression were 87.1% and 76.7%, respectively. Factors associated with viral suppression were transition at ≥ 20 years of age (aOR 4.38, 95% CI 1.41-13.65) and receiving first-line ART regimen, compared to second- or third-line regimens, at transition (aOR 6.05, 95% CI 1.55-23.58). <b>Conclusion:</b> Transition outcomes of AYHIV in our setting were suboptimal. There is a need for interventions to support AYHIV transition during this vulnerable period.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"21 ","pages":"23259582221143673"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ef/bd/10.1177_23259582221143673.PMC9732801.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10359681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integration of Early Infant Diagnosis of HIV Services Into Village Health Clinics in Ntcheu, Malawi: An Exploratory Qualitative Study.","authors":"Felix Chinguwo, Alinane Linda Nyondo-Mipando","doi":"10.1177/2325958220981256","DOIUrl":"10.1177/2325958220981256","url":null,"abstract":"<p><p>Integration of Early Infant Diagnosis(EID) of HIV into Village Health Clinics (VHCs) would increase the uptake of services. This study assessed mothers and health care workers' acceptability of integration of EID of HIV services into VHCs in Ntcheu, Malawi. We conducted an exploratory qualitative study in the phenomenological tradition among 20 mothers of either HIV exposed or non-exposed infants and 18 health care workers (HCWs) from February to July 2019. We analyzed the data using a thematic approach and guided by the theoretical framework for acceptability. There were positive perceptions of the integration of services. Acceptability is influenced by attitudes, perceived burden, intervention coherent services, and perceived effectiveness of services. The successful integration of EID of HIV into VHCs requires strengthening of the health system and community awareness. Efforts to mitigate stigma should be prioritized when integrating the services to optimize uptake of the services at a community level.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"20 ","pages":"2325958220981256"},"PeriodicalIF":2.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3a/c6/10.1177_2325958220981256.PMC7876752.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10292176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kinna Thakarar, Amoli Kulkarni, Sara Lodi, Alexander Y Walley, Marlene C Lira, Leah S Forman, Jonathan A Colasanti, Carlos Del Rio, Jeffrey H Samet
{"title":"Emergency Department Utilization Among People Living With HIV on Chronic Opioid Therapy.","authors":"Kinna Thakarar, Amoli Kulkarni, Sara Lodi, Alexander Y Walley, Marlene C Lira, Leah S Forman, Jonathan A Colasanti, Carlos Del Rio, Jeffrey H Samet","doi":"10.1177/23259582211010952","DOIUrl":"10.1177/23259582211010952","url":null,"abstract":"<p><p>Chronic pain among people with HIV (PWH) is a driving factor of emergency department (ED) utilization, and it is often treated with chronic opioid therapy (COT). We conducted a cross-sectional analysis of a prospective observational cohort of PWH on COT at 2 hospital-based clinics to determine whether COT-specific factors are associated with ED utilization among PWH. The primary outcome was an ED visit within 12 months after study enrollment. We used stepwise logistic regression including age, gender, opioid duration, hepatitis C, depression, prior ED visits, and Charlson comorbidity index. Of 153 study participants, n = 69 (45%) had an ED visit; 25% of ED visits were pain-related. High dose opioids, benzodiazepine co-prescribing, and lack of opioid treatment agreements were not associated with ED utilization, but prior ED visits (p = 0.002), depression (p = 0.001) and higher Charlson comorbidity score (p = 0.003) were associated with ED utilization. COT-specific factors were not associated with increased ED utilization among PWH.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"20 ","pages":"23259582211010952"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/af/10.1177_23259582211010952.PMC8072919.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9345256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ndidiamaka N. Amutah-Onukagha, M. Mahadevan, I. Opara, M. Rodriguez, Aminah Baxter, Megan Trusdell, J. Kelly
{"title":"Comment on Project THANKS: Examining HIV/AIDS-Related Barriers and Facilitators to Care in African American Women: A Community Perspective","authors":"Ndidiamaka N. Amutah-Onukagha, M. Mahadevan, I. Opara, M. Rodriguez, Aminah Baxter, Megan Trusdell, J. Kelly","doi":"10.1177/2325958220936406","DOIUrl":"https://doi.org/10.1177/2325958220936406","url":null,"abstract":"The aim of Project THANKS (Turning HIV/AIDS into Knowledge for Sisters) was to provide resources for African American women living with a dual diagnosis of HIV and associated comorbidities such as a chronic illness, and substance use disorder. HIV self-management is viewed within a larger context that addresses HIV and comorbidities concurrently. Project THANKS is an evidence-based, culturally competent curriculum that provides African American women with the necessary knowledge and tools to manage their complications associated with having multiple chronic diseases. The intervention was piloted in 2015 and later conducted in 2018 in 3 community-based health centers in New Jersey. Future interventions of Project THANKS will address the social support, mental health, and health literacy needs expressed by participants as well as incorporating a licensed social worker to further improve their physical and mental health outcomes.","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2325958220936406","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49098828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashley J. Mayo, E. Montgomery, Kristine Torjesen, T. Palanee-Phillips, Nitesha Jeenarain, Linly Seyama, K. Woeber, Ishana Harkoo, K. Reddy, F. Ssewamala, C. Mellins, F. Makumbi, T. Neilands, M. McKay, Christopher Damulira, P. Nabunya, O. Bahar, G. Nakigozi, William Byansi, Miriam N Mukasa, Flavia Namuwonge
{"title":"Oral Abstracts From Adherence 2019 Conference","authors":"Ashley J. Mayo, E. Montgomery, Kristine Torjesen, T. Palanee-Phillips, Nitesha Jeenarain, Linly Seyama, K. Woeber, Ishana Harkoo, K. Reddy, F. Ssewamala, C. Mellins, F. Makumbi, T. Neilands, M. McKay, Christopher Damulira, P. Nabunya, O. Bahar, G. Nakigozi, William Byansi, Miriam N Mukasa, Flavia Namuwonge","doi":"10.1177/2325958219892705","DOIUrl":"https://doi.org/10.1177/2325958219892705","url":null,"abstract":"","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2325958219892705","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45173159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinician Barriers and Facilitators to Routine HIV Testing: A Systematic Review of the Literature.","authors":"Ann Dalton Bagchi, Tracy Davis","doi":"10.1177/2325958220936014","DOIUrl":"https://doi.org/10.1177/2325958220936014","url":null,"abstract":"<p><strong>Background: </strong>Routine HIV screening rates are suboptimal.</p><p><strong>Objectives: </strong>This systematic review identified barriers to/facilitators of routine HIV testing, categorized them using the socioecological model (SEM), and provided recommendations for interventions to increase screening.</p><p><strong>Data sources: </strong>Included articles were indexed in PubMed, EBSCO CINAHL, Scopus, Web of Science, and the Cochrane Library between 2006 and October 2018.</p><p><strong>Eligibility criteria: </strong>Included studies were published in English or Spanish and directly assessed providers' barriers/facilitators to routine screening.</p><p><strong>Data extraction: </strong>We used a standardized Excel template to extract barriers/facilitators and identify levels in the SEM.</p><p><strong>Data synthesis: </strong>Intrapersonal factors predominated as barriers, while facilitators were directed at the institutional level.</p><p><strong>Limitations: </strong>Policy barriers are not universal across countries. Meta-analysis was not possible. We could not quantify frequency of any given barrier/facilitator.</p><p><strong>Conclusions: </strong>Increasing reimbursement and adding screening as a quality measure may incentivize HIV testing; however, many interventions would require little resource investment.</p>","PeriodicalId":17328,"journal":{"name":"Journal of the International Association of Providers of AIDS Care","volume":"19 ","pages":"2325958220936014"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2325958220936014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38089738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}