Journal of the Bangladesh Society of Anaesthesiologists最新文献

{"title":"A comparative study of caudal epidural bupivacaine with bupivacaine plus fentanyl and bupivacaine plus neostigmine for anaesthesia and postoperative analgesia in children undergoing sub-umbilical surgeries","authors":"Mizanur Rahman, Md Habibur Rahmn, M. Kamrujjaman, Md Shafiqul Islam","doi":"10.3329/jbsa.v32i1.66546","DOIUrl":"https://doi.org/10.3329/jbsa.v32i1.66546","url":null,"abstract":"Background: Single-shot caudal anaesthesia with local anaesthetic has a limited duration of action.Therefore, many children undergoing sub-umbilical surgery with caudal analgesia require furtheranalgesia during the postoperative period. This study compared the effect of single-dose caudal epiduralbupivacaine, bupivacaine plus fentanyl and bupivacaine plus neostigmine for anaesthesia andpostoperative analgesia in children.\u0000Objective: To evaluate effectiveness of bupivacaine with the addition of fentanyl or neostigmine forcaudal anaesthesia and analgesia in children undergoing sub-umbilical surgeries.\u0000Methods: Total ninety (90) paediatric patients, aged 2-8 years with ASA(American society ofanesthesiologist) grades I & II who were scheduled for surgery in Sher-E-Bangla Medical college Hospital,Barisal were included in this study. Data were collected by using a pre-designed questionnaire. Thepatients were randomly allocated to one of the three groups. Group A was received caudal 1 ml/kg ofbupivacaine 0.25%, Group B 1 ml/kg of bupivacaine 0.25% with fentanyl 1 μg/kg and Group C 1 ml/kgof bupivacaine 0.25% with neostigmine 2 μg/kg. Heart rate (HR), Blood pressure (BP), oxygen saturation(SpO2), Respiratory rate (RR) were recorded during operation and every five minutes thereafter. Theduration of analgesia was defined as the time from caudal injection to first dose of rescue analgesia.Rescue analgesia was given for an objective pain scale (greater than or equal to) 4 in the form of oralparacetamol (15mg/kg).\u0000Results: Assessment of anaesthesia was significantly longer in the two groups of children who receivedadditives compared with local anaesthetics group alone (p<0.01). Mean time to first postoperativeanalgesic administration was 167.37±17.30 min, 280.57±14.40min, and 357.77±19.08 min in groupA, Group B, and group C respectively. The difference was statistically significant (p<0.01) between thethree groups. In these cases duration of analgesia was considered from the placement of caudal to firstanalgesia.\u0000Conclusion: Addition of fentanyl or neostigmine to bupivacaine prolonged the duration of surgicalanaesthesia and postoperative analgesia after a single shot caudal injection with minimal incidence ofside effects in children undergoing sub-umbilical surgeries. This could be a safe and cheap alternative toextradural catheter placement for surgical procedures of intermediate duration.\u0000JBSA 2019; 32(1): 3-9","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83283155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Intravenous Paracetamol Pretreatment for Prevention of Pain on Propofol Injection: A Randomized Placebo-Controlled Study","authors":"Muhammad Sazzad Hossain, Md. Shahidul Islam, M. M. Rashid, Md Anisur Rahman Babu, Devashis Saha","doi":"10.3329/jbsa.v32i1.66549","DOIUrl":"https://doi.org/10.3329/jbsa.v32i1.66549","url":null,"abstract":"Background and aim of study: Propofol, most frequently used intravenous anesthetic, is used forinduction of routine elective surgical procedure. Pain on propofol injection (POPI) still remains aconsiderable concern for the anesthesiologist. A number of techniques has been tried to minimize propofolinducedpain with variable results. Aim of this prospective randomized study is to observe the efficacy ofintravenous paracetamol injection as pretreatment for the prevention of pain caused by the propofolinjection.\u0000Materials and Methods: A total of 80 patients were selected in this study with the age group of 20 to 50years of either sex, ASA grade I and II, scheduled for routine elective surgical procedure under generalanesthesia with endotracheal intubation. The patients enrolled were divided randomly into two groupsof 40 patients each. Group I received 50 mg of intravenous paracetamol in 10 ml. Group II (placebogroup) received 10 ml of 0.9% intravenous normal saline. The patients were asked to report their painduring injection of propofol according to the McCririck and Hunter S scale.For all statistical tests, p<0.05 was taken to indicate a significant difference.\u0000Results: The incidence of pain experienced in paracetamol group is 25% patients and in saline group is70% patients, which is statistically significant p<0.05. The severity of POPI is also lower in paracetamolgroup than the saline group (p<0.05). The incidence of mild and moderate pain in paracetamol groupsversus saline group was 17.5% versus 45% and 7.5% versus 25% respectively p<0.05. There was nosevere pain recorded in any groups.\u0000Conclusion: Pretreatment of intravenous paracetamol is effectively reduces pain on propofol injection.\u0000JBSA 2019; 32(1): 24-27","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85006518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Intrathecal Dexmedetomidine as Adjuvant to Hyperbaric Bupivacaine for Total Abdominal Hysterectomy: A Double Blind Control Study","authors":"A. Jabbar, Kawsar Begum, R. Laila, K. Sardar, Raihan Uddin, Mushfiqur Rahman, Muslema Begum","doi":"10.3329/jbsa.v32i1.66548","DOIUrl":"https://doi.org/10.3329/jbsa.v32i1.66548","url":null,"abstract":"Aims and Objectives: The aim of this study is to evaluate the effects of Dexmedetomidine as intrathecaladjuvant to Bupivacaine in spinal anaesthesia on the onset and duration of sensory and motor block inTotal Abdominal Hysterectomy (TAH).\u0000Materials and Method: Sixty patients of ASA status I and II posted for Total Abdominal Hysterectomywere randomly divided into three groups. Group C were administered Hyperbaric Bupivacaine 15mgplus 0.5 ml normal saline, Group D was administered Hyperbaric Bupivacaine 15mg + Dexmedetomidine10mg in 0.5 ml normal saline. Duration and quality of sensory and motor block were assessed.\u0000Results: Sensory and motor block in group D patients were longer than group C patients.\u0000Conclusion: Intrathecal dexmedetomidine when added to bupivacaine heavy (0.5%) provide better andprolonged analgesia.\u0000JBSA 2019; 32(1): 18-23","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79478269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Fentanyl With Bupivacaine During Spinal Anaesthesia for Caesarean Section in Reducing Hypotension","authors":"Md Al Mamun, Md Rabiul Alam, Suraya Akter, Mozibul Haque","doi":"10.3329/jbsa.v32i1.66550","DOIUrl":"https://doi.org/10.3329/jbsa.v32i1.66550","url":null,"abstract":"Background and Objectives: The hypotension following spinal anaesthesia is a common problem incaesarean section. The combination of reduced dose of local anaesthetics with intrathecal opioids makesit possible to achieve adequate spinal anaesthesia with minimum hypotension. We investigated whetherthis synergistic phenomenon could be used to provide less frequent hypotension while incurring adequatespinal anaesthesia for caesarean section.\u0000Methods: Sixty women scheduled for caesarean delivery (thirty in each group) were divided into twogroups of patients who received a spinal injection of either 12.5 mg of hyperbaric bupivacaine or 10 mgof hyperbaric bupivacaine with 25 mg fentanyl added. Each measurement of a systolic blood pressureless than 95 mmHg or a decrease in systolic pressure of greater than 25% from baseline was consideredas hypotension and treated with a bolus of 5 to 10 mg of intravenous ephedrine. The quality of surgicalanaesthesia was evaluated also.\u0000Results: Spinal block provided excellent surgical anaesthesia in almost all patients. Peak sensory levelwas higher (D2-3 vs. D4-5) and motor block was more intense in the hyperbaric bupivacaine group; thepatients from bupivacaine group were more likely to require treatment for hypotension (75% vs. 15%)and had more persistent hypotension (4.6 vs. 1.0 hypotensive measurements per patient) than patients inthe reduced bupivacaine-fentanyl group. Mean ephedrine requirements were 15.0 mg and 3.5 mg,respectively. Patients in the bupivacaine group also complained of emetic effects more frequently thanpatients in the reduced dose bupivacaine-fentanyl group.\u0000Conclusions: Bupivacaine 10 mg plus fentanyl 25 mg provided spinal anaesthesia for caesarean deliverywith less hypotension and vasopressor requirements while ensuring excellent perioperative surgical anaesthesia.\u0000JBSA 2019; 32(1): 28-34","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81346271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Procedural Sedation & Analgesia by Ketamine-Propofol (Ketofol) And Ketamine-Diazepam Combination In Day Case Surgery - A Comparative Study","authors":"F. Kalam, P. Hussain, Masud Ahmed, Abdullah Masum","doi":"10.3329/jbsa.v31i2.66491","DOIUrl":"https://doi.org/10.3329/jbsa.v31i2.66491","url":null,"abstract":"Introduction: Traditionally Procedural Sedation and Analgesia (PSA) is provided by various drugsand its combinations with mixed effect regarding safety and efficacy.\u0000Objective: The aim of the study was to compare the combination of Ketamine & Propofol (Ketofol) andKetamine-Diazepam for PSA in day case surgery.\u0000Materials & Methods: This prospective study was carried out in CMH Dhaka on sixty patients equallydivided in two groups between the period of May 2015 to September 2015. Group I patients receivedInjection Ketamine 1mg/kg & Injection Propofol 1mg/kg combination while group II patients receivedInjection Ketamine 2mg/kg & Injection Diazepam 0.2mg/kg combination. Clinical parameters like pulserate, non invasive blood pressure (NIBP), percentage saturation of oxygen (SpO2) were monitored, recordedand analyzed. Recovery was assessed by Aldred Recovery Score (ARS) and compared between groups.\u0000Results: Rise of heart rate, systolic blood pressure (SBP), diastolic blood pressure (DBP) were statisticallysignificant in group II patients when compared to group I both during the procedure & recovery but riseof mean arterial pressure (MAP) was significant only during procedure. The recovery time in group IIpatients (24.7 ± 3.6 min) was significantly higher (29.7 ± 4.1 min) than group I patients. Side effects likeexcessive bronchial secretion and postoperative agitation were also significantly lesser in Ketofol group.\u0000Conclusion: Ketofol provides safer and more effective sedation and analgesia than Ketamine andDiazepam combination.\u0000JBSA 2018; 31(2): 75-82","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79347150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anesthetic Management of a Patient with Severe Dilated Cardiomyopathy: Case Report","authors":"Md Shafiul Alam Shaheen, A. Chowdhury, Md. Mushfiqur Rahman, Mahabubul Hasan, Raju Ahmed","doi":"10.3329/jbsa.v31i2.66494","DOIUrl":"https://doi.org/10.3329/jbsa.v31i2.66494","url":null,"abstract":"Anesthetic management of patients with dilated cardiomyopathy (DCM) is a challenge to theanesthesiologist, due to poor left systolic function, ventricular enlargement, risk of malignant arrhythmiasand sudden cardiac death. Therefore, preoperative assessment and appropriate anesthetic managementare important in patients with DCM. Five to eight people per 100,000 develop this disorder each year.Malignant arrhythmias are the most common cause of death in DCM.1 Around 50% of cases ofnonischaemic dilated cardiomyopathy is idiopathic. Other causes are familial, infectious, infiltrativeand connective tissue diseases. This is a report of successful anesthetic management of a patient withsevere DCM undergoing laparoscopic cholecystectomy using general anesthesia (GA).\u0000JBSA 2018; 31(2): 95-98","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"100 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76839303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of plethysmographic variability index for prediction of subarachnoid block induced hypotension in caesarean section","authors":"Md Abdul Alim, Akm Habibullah, R. Ghosh, R. Ghosh, D. Banik, A. Akhtaruzzaman","doi":"10.3329/jbsa.v31i2.66485","DOIUrl":"https://doi.org/10.3329/jbsa.v31i2.66485","url":null,"abstract":"Background: Hypotension is frequently observed after spinal anaesthesia for cesarean section and canbe detrimental to both mother and baby. The pleth variability index (PVI) is a new algorithm used forautomatic estimation of respiratory variations in pulse oximeter waveform amplitude, which mightpredict fluid responsiveness. Because anaesthesia-induced hypotension may be partly related to patientvolume status. The pleth variability index (PVI) was developed as a noninvasive bedside measurementof this variation in the pulse oximetry waveform.\u0000Objective: To observe the hypotension predictive capacity of PVI and to find out association & correlationof PVI with sphygmomanometeric blood pressure measurement.\u0000Methods: This observational study was carried out in the department of anaesthesia, Analgesia andIntensive Care Medicine Bangabandu Sheikh Mujib Medical University, Dhaka between July 2015 toDec 2015. A total 100 elective caesarean section patients under subarachnoid block were selected by theinclusion and exclusion criteria. Patients who fulfill the ASA physical status i, ii. and full term singletonpregnancy height from 152cm to160cm. were included and patients suffering from obesity (bodyweight>115 kg), hypertension, COPD, bronchial asthma, haemoglobinopathies, severe anaemia,arrythmia, heart failure, any congenital heart disease, pre-eclampsia, total placenta praevia or patientwho took anti hypertensive medications were excluded from the study. Patients were divided in twogroups, PVI ³22.0 in group-A and PVI <22.0 in group-B.Dehydration was corrected 10 min before sub arachnoid block (sab). Pre–anesthetic Himoglobin% SPO2,Heart rate, PVI & blood pressure was recorded at baseline after 5 minutes of rest by one anesthesiologist.Subarachnoid block performed with 0.5% hyperbaric bupivacaine (12.5 mg) at the L3-L4 intervertebralspace on sitting position. After spinal block patient was returned to supine position with a wedge underbuttock to facilitate left uterine displacement. Oxygen 4 lit/min was administered via face mask.Immediately after sub arachnoid block Spo2, heart rate, SBP and DBP was recorded by anotheranesthesiologist at 2 minutes interval in first 10 minute. Surgical incision was allowed when a blocklevel at least T6 dermatome was obtained with cold & pin prick.All data was recorded by two anesthesiologist who were not involved in the study. The study ended withdelivery of the baby. Chi-Square test was used to analyze the categorical variables, shown with cross tabulation.Student t-test was used for continuous variables. p value <0.05 was considered as statistically significantly.\u0000Result: In baseline, majority (58.0%) patients was found PVI e”22 (group A) and 42(42.0%) was PVI <22(group B). Mean age of the patients was 27.5±4.5 years, Mean heart rate was found 93.2±5.8 beats/minin group A and 89.7±12.7 beats/min in group B. The mean systolic BP was found 132.1±7.7 mmHg ingroup A and 128.7±8.5 mmHg in group B. The mean diastolic BP was ","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86851806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Ephedrine for Management of Hypotension During Spinal Anaesthesia for Caesarean Delivery","authors":"Esrat Zahan, Md Zakir Hossain, A. Rahman, Waheeda Nargirs","doi":"10.3329/jbsa.v31i2.66493","DOIUrl":"https://doi.org/10.3329/jbsa.v31i2.66493","url":null,"abstract":"Background: Hypotension during spinal anaesthesia for caesarean section remains a common scenarioin our clinical practice. Certain risk factors play a role in altering the incidence of hypotension. Ephedrinehas been the drug of choice for more than 30 years in the treatment of spinal anesthesia induced maternalhypotension. It has a good safety record, ready availability, and familiarity to most anesthesiologists.\u0000Aims: To determine the efficacy and safety of prophylactic bolus dose of 0.5 mg/kg intravenous ephedrinefor the prevention of hypotension during spinal anesthesia for cesarean delivery.\u0000Methods: It was designed a randomized, double-blinded study. Patients were randomly allocated intotwo groups: ephedrine group (n=30) and control group (n=30). Intravenous preload of 15 mL/kg lactatedRinger’s solution was given. Shortly after the spinal injection, ephedrine0.5 mg/kg or saline was injectedintravenous for 60 sec.\u0000Results: The mean of highestand lowest heart rate in the ephedrine group was higher than those ofcontrol group (p<0.05). There were significant lower incidences of hypotension and nauseaand vomitingin the ephedrine group compared with the control group 11(36.7%) vs. 24(80.0%); 6(20.0%) vs. 17 (56.7%),respectively) (p<0.05). The first rescue ephedrine time in the ephedrine group was significantly longer(14.9±7.1 min vs. 7.9±5.4 min) than that of the control group (p<0.05). Neonatal outcome were similarbetween the study groups.\u0000Conclusion: The above findings suggest, the prophylactic bolus dose of 0.5 mg/kg intravenous ephedrinegiven at the time of intrathecal block after a crystalloidfluid preload, plus rescue boluses reduce theincidence of hypotension.\u0000JBSA 2018; 31(2): 88-94","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"213 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77748137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teamwork Practice In Operation Theatre for Patient Safety – Bangladesh perspective","authors":"D. Banik","doi":"10.3329/jbsa.v31i2.66482","DOIUrl":"https://doi.org/10.3329/jbsa.v31i2.66482","url":null,"abstract":"Abstract not available\u0000JBSA 2018; 31(2): 50-52","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79661741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Magnesium Sulphate to Prevent Arterial Pressure Increases During Laparoscopic Cholecystectomy","authors":"N. Hoq, A. Maruf","doi":"10.3329/jbsa.v31i2.66492","DOIUrl":"https://doi.org/10.3329/jbsa.v31i2.66492","url":null,"abstract":"Background: Carbon dioxide pneumoperitoneum (PP) for laparoscopic surgery increases arterialpressure and systemic vascular resistance, these vasopressor responses are likely to be due to increasedrelease of catecholamine. Magnesium is well known to inhibit catecholamine release and attenuatevasopressin stimulated vasoconstriction.\u0000Objectives: This study has been undertaken with a view to find out the efficacy of magnesium sulphateto prevent arterial pressure increases associated with carbon dioxide pneumoperitoneum (PP) in patientsundergoing laparoscopic cholecystectomy.\u0000Methods: Sixty patients, of either sex, 18 60 years of age, undergoing elective laparoscopic cholecystectomywere randomly allocated in one of the two group’s containing 30 patients each. Magnesium SulphateGroup “M” received magnesium sulphate 30 mg/kg intravenously as a bolus beforecarbon dioxidepneumoperitoneum (PP).A control Group “C” received same volume of normal salinebefore carbon dioxidepneumoperitoneum (PP).\u0000Results: Mean arterial pressure was significantly less throughout the period ofpneumoperitoneum inpatients of Group M. Intravenous labetalol was required in 46.66% (14out of 30) of the patients in groupC to control intraoperative hypertension and it was clinicallysignificant in comparison to group M.\u0000Conclusion: Our study concluded that intravenous Magnesium Sulphate administered before carbondioxide pneumoperitoneum (PP) attenuates arterial pressure increases during laparoscopiccholecystectomy effectively and provides better hemodynamic stability.\u0000JBSA 2018; 31(2): 82-87","PeriodicalId":17242,"journal":{"name":"Journal of the Bangladesh Society of Anaesthesiologists","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85834016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}