Journal of Science: Advanced Materials and Devices最新文献_第4页

Magnetic field-assisted electrodeposition: Mechanisms, materials, and multifunctional applications 磁场辅助电沉积：机制、材料和多功能应用

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-08-06 DOI: 10.1016/j.jsamd.2025.100967

Xiayu Leng, Shunli He, Weiqiang Wang, Haonan Zhang, Linyue Wang, Jianli Song

{"title":"Magnetic field-assisted electrodeposition: Mechanisms, materials, and multifunctional applications","authors":"Xiayu Leng, Shunli He, Weiqiang Wang, Haonan Zhang, Linyue Wang, Jianli Song","doi":"10.1016/j.jsamd.2025.100967","DOIUrl":"10.1016/j.jsamd.2025.100967","url":null,"abstract":"<div><div>Magnetic field-assisted electrodeposition (MFAED) is an emerging electrochemical strategy for tailoring functional coatings with controllable morphology, crystallographic orientation, and interfacial properties. By introducing external magnetic fields, MFAED dynamically regulates ion transport, nucleation kinetics, and grain growth through Lorentz forces, magnetic field gradients, and magnetohydrodynamic (MHD) convection. These field-induced phenomena enhance mass transport and promote anisotropic crystal evolution, effectively addressing limitations associated with conventional electrodeposition. This review provides a comprehensive overview of MFAED fundamentals, including magnetic field configurations, deposition mechanisms, and the influence of field strength and orientation on structure–property relationships. Recent progress in multiphysics modeling is also examined to elucidate coupled electrochemical–hydrodynamic interactions and inform process optimization strategies. Representative applications of MFAED in energy storage, microelectronics, and biomedical coatings are discussed, with emphasis on improvements in catalytic activity, electrical conductivity, corrosion resistance, and biocompatibility. Persistent challenges—such as limited scalability, inconsistent coating uniformity, and incomplete understanding of coupled-field phenomena—are critically assessed. Future research directions are highlighted, including the integration of programmable field control, coupling with hybrid stimuli (e.g., ultrasound, pulsed currents), and application to flexible or topographically complex substrates. Collectively, these insights establish a foundation for advancing MFAED as a versatile platform for next-generation surface and interface engineering.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100967"},"PeriodicalIF":6.8,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144810031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FeS2 nanoplates embedded in rGO sheets: A novel nanostructured counter electrode for enhanced DSSC efficiency 嵌入氧化石墨烯片中的FeS2纳米片：一种新型纳米结构对电极，可提高DSSC效率

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-08-06 DOI: 10.1016/j.jsamd.2025.100962

T. Sasikala , S. Deivanayaki , M. Saravanakumar , M. Aslam Manthrammel , Mohd Shkir , N. Senthil Kumar , Sambasivam Sangaraju

{"title":"FeS2 nanoplates embedded in rGO sheets: A novel nanostructured counter electrode for enhanced DSSC efficiency","authors":"T. Sasikala , S. Deivanayaki , M. Saravanakumar , M. Aslam Manthrammel , Mohd Shkir , N. Senthil Kumar , Sambasivam Sangaraju","doi":"10.1016/j.jsamd.2025.100962","DOIUrl":"10.1016/j.jsamd.2025.100962","url":null,"abstract":"<div><div>Transition metal sulfides (TMS) have gained significant attention as cost-effective, platinum-free alternatives for counter electrodes (CEs) in dye-sensitized solar cells (DSSCs). This work presents a novel nanohybrid composed of hexagonal FeS<sub>2</sub> (iron pyrite) nanoplates integrated onto reduced graphene oxide (rGO) sheets as an efficient CE for DSSCs. The nanohybrid was synthesized through a facile one-step solvothermal process and thoroughly characterized, revealing the formation of uniformly distributed crystalline FeS<sub>2</sub> nanoplates (1 μm in length and 70 nm in thickness) intricately embedded onto the rGO surface. This innovative FeS<sub>2</sub>/rGO hybrid demonstrated an impressive power conversion efficiency (PCE) of 6.23 %, significantly outperforming the 4.63 % PCE of standalone FeS<sub>2</sub> nanostructures and even exceeding the 5.89 % efficiency achieved by the conventional Pt-based DSSC. The superior performance is attributed to the synergistic effect of the catalytically active FeS<sub>2</sub> nanoplates and the electrically conductive two-dimensional rGO framework. This unique architecture enhances the density of catalytically active sites and accelerates ion diffusion pathways, leading to outstanding electrocatalytic activity for triiodide reduction. These results highlight the FeS<sub>2</sub>/rGO nanohybrid's potential as a highly efficient and sustainable alternative to traditional platinum-based CEs in DSSCs.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100962"},"PeriodicalIF":6.8,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144853020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Copper-based composite sintering materials and reliability analysis for power electronics packaging 电力电子封装用铜基复合烧结材料及可靠性分析

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-08-05 DOI: 10.1016/j.jsamd.2025.100963

Xinyue Wang , Zhoudong Yang , Letao Bian , Wenting Liu , Guoqi Zhang , Jing Zhang , Chuantong Chen , Pan Liu

{"title":"Copper-based composite sintering materials and reliability analysis for power electronics packaging","authors":"Xinyue Wang , Zhoudong Yang , Letao Bian , Wenting Liu , Guoqi Zhang , Jing Zhang , Chuantong Chen , Pan Liu","doi":"10.1016/j.jsamd.2025.100963","DOIUrl":"10.1016/j.jsamd.2025.100963","url":null,"abstract":"<div><div>While silver-based sintered materials are limited by cost and electromigration, and copper faces challenges with oxidation at high temperatures, Cu-based composite sintering materials offer promising alternative solutions. This review examines recent advances in Cu-based composite sintered materials for die-attach in power electronics packaging, focusing on their mechanical, thermal, electrical properties, and reliability. This review systematically categorizes such compounding strategies, including direct mixing, core-shell structures, and alloying, analyzing the impact on composite properties. Furthermore, the reliability of Cu-based composite sintered joints is evaluated, addressing high-temperature storage, thermal cycling, corrosion, and electrochemical migration. Challenges such as oxidation resistance, process optimization, and cost-effectiveness are discussed, together with future research directions. This work aims to support researchers in advancing Cu-based composite sintering materials research and development, broadening material options for high-temperature power electronics packaging applications.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100963"},"PeriodicalIF":6.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144842807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in resistive switching memory devices based on diverse material platforms for next generation electronics 基于不同材料平台的下一代电子器件电阻开关存储器件的最新进展

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-08-05 DOI: 10.1016/j.jsamd.2025.100960

Wonseop Shin , Sungho Jang , Hyojung Kim

{"title":"Recent advances in resistive switching memory devices based on diverse material platforms for next generation electronics","authors":"Wonseop Shin , Sungho Jang , Hyojung Kim","doi":"10.1016/j.jsamd.2025.100960","DOIUrl":"10.1016/j.jsamd.2025.100960","url":null,"abstract":"<div><div>The fast evolution of information technology has significantly increased the demand for high-performance electronic devices, yet silicon-based hardware still faces fundamental challenges in fulfilling these requirements. Consequently, various alternatives, including metal oxides, biomaterials, and 2D materials, have received considerable attention. Notably, resistive switching memory (RS memory) stands out due to its low power consumption and quick switching capability, and it presents promising prospects for emerging data storage. This article thoroughly explores the essential substances and mechanisms that support RS memory, carefully examining the features and transition processes of multiple candidates, such as halide perovskites (HPs), metal oxides, polymers, biomaterials, and 2D structures. In addition, it clarifies the fundamental operation of ECM (electrochemical metallization) and VCM (valence change mechanism) based resistive-switching random-access memory (RRAM) devices, thoroughly comparing their benefits and possible drawbacks. This investigation highlights the promise of RS memory and identifies key materials and processes ready to promote further progress in upcoming electronic innovations and memory solutions for next-generation systems.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100960"},"PeriodicalIF":6.8,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144781317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the way to eco-friendly fabrication of polyaniline-based ammonia sensors with high sensitivity and room temperature operation 基于聚苯胺的常温高灵敏度氨传感器的环保制造之路

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-07-30 DOI: 10.1016/j.jsamd.2025.100961

Sabine Vassaux, Nathalie Redon, Caroline Duc

{"title":"On the way to eco-friendly fabrication of polyaniline-based ammonia sensors with high sensitivity and room temperature operation","authors":"Sabine Vassaux, Nathalie Redon, Caroline Duc","doi":"10.1016/j.jsamd.2025.100961","DOIUrl":"10.1016/j.jsamd.2025.100961","url":null,"abstract":"<div><div>Organic sensors based on conductive polyaniline (PAni) are a promising solution under development for detecting ammonia. The sensors are advantageous due to their performance, their low cost of production and ease of processing. During the fabrication of sensors, the polymer, and its doping agent are usually dispersed in an organic solvent (e.g., m-cresol or N-methyl-2-pyrrolidone), which does not meet the required safety and sustainability standards. The aim of this study is to report the remarkable detection performances of polyaniline-based sensitive layers elaborated in safer solvents. Herein, PAni doped with camphor-10-sulfonic acid (CSA) was mixed and mechanically dispersed in various solvents. Obtained PAni:CSA films were analyzed using infrared spectroscopy, while morphological characteristics were determined using Scanning Electron Microscopy. The analysis of detection performances shows that the solvent employed for the dispersion of PAni has a significant effect on the sensor's sensitivity. For instance, high sensitivities (about 300 %/ppm) and low limits of detection (approximately 2 ppb) are obtained for devices elaborated in ethanol and <span>dl</span>-limonene. After evaporation, these incompatible solvents lead to the formation of a porous active layer, facilitating the interactions with ammonia. The sensitivities of these devices remain stable after 5 months, independent of the humidity level. Thus, using non-stabilizing solvents to disperse polyaniline offers a promising approach to enhance the sensitivity and limit the detection of room-temperature organic ammonia sensors.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100961"},"PeriodicalIF":6.8,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144781374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Room-temperature synthesized CsPbI3 nanocrystals for liquid luminescent antennas in visible light communication 室温合成CsPbI3纳米晶体用于可见光通信中的液体发光天线

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-07-25 DOI: 10.1016/j.jsamd.2025.100959

Qian Wang , Yichi Zhong , Jian Huang , Hongyu Yang , Zhanpeng Wang , Hongbin Li , Jingzhou Li

{"title":"Room-temperature synthesized CsPbI3 nanocrystals for liquid luminescent antennas in visible light communication","authors":"Qian Wang , Yichi Zhong , Jian Huang , Hongyu Yang , Zhanpeng Wang , Hongbin Li , Jingzhou Li","doi":"10.1016/j.jsamd.2025.100959","DOIUrl":"10.1016/j.jsamd.2025.100959","url":null,"abstract":"<div><div>All-inorganic perovskite semiconductor nanocrystals exhibit high photoluminescence efficiency and hold significant potential for applications in visible light optical communication. In this study, a room-temperature resting method was developed to synthesize CsPbI<sub>3</sub> nanocrystals, eliminating the need for heating, stirring, or ultrasound. This approach offers a straightforward, energy-efficient preparation process. By precisely controlling the micro-solubility of Cs<sub>2</sub>CO<sub>3</sub> and PbI<sub>2</sub> in the reaction solution, we facilitated the nucleation and growth of CsPbI<sub>3</sub> nanocrystals at room temperature. The synthesized nanocrystals exhibit both linear and block-like morphologies with excellent optical properties. Moreover, slight increases in reaction temperature enable effective control over size distribution and luminescence characteristics. Experimental results demonstrate the potential application of CsPbI<sub>3</sub>-based liquid luminescent antennas in visible light communication, with signal stability and bit error rate measurements indicating promising commercial prospects for low-cost optical devices.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100959"},"PeriodicalIF":6.8,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144724143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green synthesis of silver/zinc oxide plasmonic nanocomposites using Moringa oleifera: A dual-function strategy for photocatalysis and dye-sensitized solar cell performance 利用辣木绿色合成银/氧化锌等离子体纳米复合材料：光催化和染料敏化太阳能电池性能的双重功能策略

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-07-24 DOI: 10.1016/j.jsamd.2025.100954

Kandasamy Muthusamy , Velu Duraisamy , Jayant Giri , Prem Gunnasegaran , Ahmad Husain , V. Vicki Wanatasappan , Mohammad Kanan

{"title":"Green synthesis of silver/zinc oxide plasmonic nanocomposites using Moringa oleifera: A dual-function strategy for photocatalysis and dye-sensitized solar cell performance","authors":"Kandasamy Muthusamy , Velu Duraisamy , Jayant Giri , Prem Gunnasegaran , Ahmad Husain , V. Vicki Wanatasappan , Mohammad Kanan","doi":"10.1016/j.jsamd.2025.100954","DOIUrl":"10.1016/j.jsamd.2025.100954","url":null,"abstract":"<div><div>Chemical methods are the primary techniques for large-scale nanomaterial synthesis, offering environmental and energy benefits; however, these methods negatively impact on the environment. To circumvent this, an eco-friendly approach produces nanoparticles that effectively degrade dyes under light exposure, showing promise in dye-sensitized solar cells (DSSCs). A sustainable green synthesis of plasmonic silver nanoparticles decorated zinc nanocomposite (Ag@ZnO PNC) by Moringa oleifera leaf extract as both reducing and capping agents by a simple solution method. Prepared plasmonic material was characterized using advanced instrumentation techniques. The photocatalytic performance of green synthesized plasmonic Ag@ZnO PNC was tested for the degradation of methylene blue under direct sunlight irradiation. The plasmonic Ag@ZnO PNC improved the photocatalytic performance by 99.33 % because of a higher amount of <strong><sup>●</sup></strong>OH production verified by the terephthalic acid experiment. Likewise, a dye-sensitized solar cell (DSSC) with Ag@ZnO NC photoanode exhibited a higher energy conversion of efficiency (PCE) of 1.76 %, which is ∼33 % higher over the PCE of DSSC with pure ZnO (1.18 %), which is attributed to the incorporation of Ag, which acts as electron sink and offered visible light extensions.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100954"},"PeriodicalIF":6.8,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144863680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optoelectronic properties of dye doped polymer based on PVA: Structural and UV–vis studies 基于PVA的染料掺杂聚合物的光电性能：结构和紫外可见性研究

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-07-22 DOI: 10.1016/j.jsamd.2025.100955

Dyari M. Mamand , Bahez Y. Ahmed , Dana S. Muhammad , Wrya O. Karim , Shujahadeen B. Aziz , Bandar A. Al-Asbahi , Abdullah A.A. Ahmed , Jamal Hassan

{"title":"Optoelectronic properties of dye doped polymer based on PVA: Structural and UV–vis studies","authors":"Dyari M. Mamand , Bahez Y. Ahmed , Dana S. Muhammad , Wrya O. Karim , Shujahadeen B. Aziz , Bandar A. Al-Asbahi , Abdullah A.A. Ahmed , Jamal Hassan","doi":"10.1016/j.jsamd.2025.100955","DOIUrl":"10.1016/j.jsamd.2025.100955","url":null,"abstract":"<div><div>This study investigates the structural and optical modifications in polyvinyl alcohol (PVA) films doped with a natural dye extracted from Cosmos sulphureus (CSC). FTIR analysis confirms the presence of functional groups in the dye, including NH, OH, and C<img>O, indicating strong intermolecular interactions with PVA and the plasticizer. The optical properties were examined using UV–vis spectroscopy, revealing a significant redshift in the absorption edge with increasing dye concentration. The optical bandgap decreased from 5.18 eV for pure PVA to 2.41 eV for PVA doped with 6 mL dye, while the Urbach energy increased from 0.35 eV to 0.39 eV, indicating enhanced structural disorder. The refractive index increased to 2.13, suggesting improved light confinement. The optical dielectric function was analyzed to assess surface and volume energy losses. At the same time, the Wemple-DiDomenico (W-D) model was applied to determine the effective oscillator energy (2.91 eV) and dispersion energy (1.13 eV). The nonlinear refractive index exhibited an increasing trend with dye concentration. These findings demonstrate that CSC dye significantly alters PVA's optical properties, making it a promising candidate for optoelectronic and photonic applications.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100955"},"PeriodicalIF":6.8,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simply structured wearable triboelectric nanogenerator with milligram-level sensitivity for biomechanical energy harvesting and motion detection 结构简单的可穿戴摩擦电纳米发电机，具有毫克级的灵敏度，用于生物力学能量收集和运动检测

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-07-21 DOI: 10.1016/j.jsamd.2025.100956

Shuting Liu , Wang Yu , Yuan Sui , Chi Zhang , Lin Shi , Shurong Dong , Liang Peng

{"title":"Simply structured wearable triboelectric nanogenerator with milligram-level sensitivity for biomechanical energy harvesting and motion detection","authors":"Shuting Liu , Wang Yu , Yuan Sui , Chi Zhang , Lin Shi , Shurong Dong , Liang Peng","doi":"10.1016/j.jsamd.2025.100956","DOIUrl":"10.1016/j.jsamd.2025.100956","url":null,"abstract":"<div><div>Wearable triboelectric nanogenerators (TENGs) often struggle to harmonize fabrication simplicity, stretchability, and high sensitivity. In this study, we present a conductive sponge-based TENG fabricated via a streamlined one-step process, which integrates a porous conductive sponge electrode with textured Ecoflex. The device achieves high pressure sensitivity (3.5 V/N and 0.647 V/N) and detects ultralight forces (14 mg), outperforming conventional designs in resolution. Its inherent flexibility ensures conformal contact during motion, while durability tests confirm stability over 25,000 cycles and resistance to liquids. The CS-SE TENG serves dual roles: as a biomechanical energy harvester, it powers small electronics via hand tapping or walking; as a self-powered sensor, it monitors sitting behavior (posture, duration) and tracks motion metrics (steps, speed, calories) through MATLAB-processed signals. Insole integration demonstrates real-time gait analysis, while chair-mounted deployment addresses sedentary health risks. By combining single-step fabrication, milligram-level sensitivity, and energy-sensing duality, this work offers a scalable platform for wearable technologies, bridging sustainable energy harvesting with precision health monitoring.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100956"},"PeriodicalIF":6.8,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomimetic MOFs nanoparticles Co-delivering oridonin and siRNA for synergistic therapy in melanoma via ferroptosis pathway 通过铁下沉途径协同治疗黑色素瘤的仿生mof纳米颗粒共递送冬凌草素和siRNA

IF 6.8 3区材料科学

Journal of Science: Advanced Materials and Devices Pub Date : 2025-07-21 DOI: 10.1016/j.jsamd.2025.100957

Kong Jiahui , Zhang Yongqiang , Yang Yuchang , Wang Ziheng , Jing Xiaohong , Lin Shuting , Chen Hongyue , Dong Xiaoxv , Qu Changhai , Cai Mengru , Ni Jian , Yin Xingbin

{"title":"Biomimetic MOFs nanoparticles Co-delivering oridonin and siRNA for synergistic therapy in melanoma via ferroptosis pathway","authors":"Kong Jiahui , Zhang Yongqiang , Yang Yuchang , Wang Ziheng , Jing Xiaohong , Lin Shuting , Chen Hongyue , Dong Xiaoxv , Qu Changhai , Cai Mengru , Ni Jian , Yin Xingbin","doi":"10.1016/j.jsamd.2025.100957","DOIUrl":"10.1016/j.jsamd.2025.100957","url":null,"abstract":"<div><div>Malignant melanoma (MM) exhibits clinical traits of vigorous metastasis and an unfavorable prognosis. Traditional therapeutic modalities such as surgical resection, radiotherapy, and chemotherapy have restricted efficacy and notable side effects, thereby urgently demanding new drugs or treatment approaches. The iron-doped zeolite imidazole ester skeleton material (Fe-ZIF-8, FZ) exhibits outstanding biological safety and acid-responsive drug release properties, serving as an excellent nano-delivery carrier. Oridonin (Ori) is capable of inducing ferroptosis in tumor cells by targeting key genes (such as GPX4, SLC7A11, GGT1), and demonstrates a potent therapeutic effect on MM. Simultaneously, small interfering RNA (siRNA) can exert a role in gene silencing. In this study, we devised biomimetic nanoparticles (NPs) based on iron-doped zeolitic imidazolate framework-8 (FZ) for the co-delivery of Ori and siRNA targeting GPX4 (siRNA<sub>GPX4</sub>). FZ was employed to co-load Ori and siRNA targeting GPX4, the core regulator of ferroptosis, to play a role in drug and gene therapy for MM. The A375 tumor cell membrane was biomimetically modified to construct anti-tumor drug targeted delivery nanoparticles, thereby achieving efficient co-delivery of Ori and siRNA<sub>GPX4</sub>. This provides a novel idea for the development of highly efficient and low-toxicity treatment of MM and the overcoming of tumor drug resistance.</div></div>","PeriodicalId":17219,"journal":{"name":"Journal of Science: Advanced Materials and Devices","volume":"10 3","pages":"Article 100957"},"PeriodicalIF":6.8,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144772124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0