Journal of the American Dental Association最新文献

{"title":"A 4-week randomized clinical trial evaluating plaque and gingivitis effects of a new oscillating-rotating electric toothbrush","authors":"Ralf Adam PhD,&nbsp;Julie Grender PhD,&nbsp;Hans Timm PhD,&nbsp;C. Ram Goyal DDS,&nbsp;Jimmy Qaqish BSc","doi":"10.1016/j.adaj.2025.04.015","DOIUrl":"10.1016/j.adaj.2025.04.015","url":null,"abstract":"<div><h3>Background</h3><div>Many patients with gingivitis use manual toothbrushes, despite evidence of considerably greater plaque and gingivitis reductions with electric toothbrushes. A new oscillating-rotating (OR) toothbrush features a streamlined design and quieter sound that manual toothbrush users may find appealing.</div></div><div><h3>Methods</h3><div>This parallel-group, 3-treatment, randomized, clinical study compared the new OR toothbrush, used in sensitive or daily clean mode, with a manual toothbrush for plaque (Rustogi Modified Navy plaque index) and gingivitis reduction (modified gingival index and number of bleeding sites) over 4 weeks among manual toothbrush users with gingivitis.</div></div><div><h3>Results</h3><div>All 3 groups experienced significant improvement in all gingivitis and plaque measures at weeks 1 and 4 (<em>P</em> ≤ .005). The OR toothbrush used in either mode had significantly greater efficacy vs the manual toothbrush for all gingivitis and plaque measures at both time points (<em>P</em> ≤ .016). Week 4 treatment difference for whole-mouth plaque reduction between the manual toothbrush and OR sensitive and OR daily clean toothbrush treatments was –0.05 (95% CI, –0.062 to –0.037) and –0.078 (95% CI, –0.091 to –0.066), respectively. Only 20% of participants in the manual group transitioned from gingivitis (≥ 10% bleeding sites) to healthy (&lt; 10% bleeding sites) vs 46.7% in the OR sensitive group and 60% in the OR daily clean group (<em>P</em> = .005).</div></div><div><h3>Conclusions</h3><div>The new OR toothbrush was significantly more effective than a manual toothbrush at reducing plaque and gingivitis in manual toothbrush users with baseline gingivitis.</div></div><div><h3>Practical Implications</h3><div>The OR toothbrush improves periodontal health outcomes for manual toothbrush users and was designed to transition them to electric technology. This clinical trial was registered at ISRCTN–The UK’s Clinical Study Registry. The registration number is ISRCTN61582326.</div></div>","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"156 8","pages":"Pages 611-619.e2"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Getting your child’s smile ready for school","authors":"Anita M. Mark","doi":"10.1016/j.adaj.2025.06.003","DOIUrl":"10.1016/j.adaj.2025.06.003","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"156 8","pages":"Page 688"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144767253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of drug-related oral and dental adverse events","authors":"Monisha Billings DDS, MPH, PhD,&nbsp;Hannah Lee BS,&nbsp;Joyance L. Mendoza BS,&nbsp;Frederick Hyman DDS, MPH,&nbsp;Darien Weatherspoon DDS, MPH,&nbsp;Vineet Dhar BDS, MDS, PhD,&nbsp;Farbod Fazilatkhoo DDS,&nbsp;Ying Zhang DDS,&nbsp;Kyungah Kim PharmD, MPH,&nbsp;Lauren Choi PharmD,&nbsp;Helen Edelberg MD, MPH","doi":"10.1016/j.adaj.2025.05.016","DOIUrl":"10.1016/j.adaj.2025.05.016","url":null,"abstract":"<div><h3>Background</h3><div>Given the high prevalence of prescription drug use in the US population and the possible drug-related oral and dental adverse events (AEs), it is important to characterize drug-related oral and dental AEs from available data sources. The objectives of this study were to identify and characterize various drug-related oral and dental AE pairs reported in the literature and drug labeling.</div></div><div><h3>Types of Studies Reviewed</h3><div>A systematic descriptive review of the literature was performed after applying the search criteria in PubMed, Embase, and Web of Science. A full-text review of drug labeling was conducted in FDALabel (US Food and Drug Administration) with natural language processing using terms from Medical Dictionary for Regulatory Activities, Version 26.0. Comparative data analysis was performed. Heat maps and tree maps were generated for drug–oral and dental AE pair characterization.</div></div><div><h3>Results</h3><div>The authors reviewed 505 published articles and 2,663 drug labelings. They identified 180 major drug–oral and dental AE pairs reported in the literature but not found in drug labeling. The drug–oral and dental AE pairs most frequently reported in the literature and listed in drug labeling were oral and dental local hypersensitivity reactions (977), Stevens-Johnson syndrome and toxic epidermal necrolysis (419), mucositis and stomatitis (337), and orofacial clefts (151). With respect to oral and dental AEs in labeling, most warnings and precautions were for drug-induced systemic lupus erythematosus and most boxed warnings were for Stevens-Johnson syndrome and toxic epidermal necrolysis.</div></div><div><h3>Conclusions and Practical Implications</h3><div>The results of this study advance understanding of major oral and dental AEs across various therapeutic areas captured in the literature and labeling. The authors characterized those drugs and drug classes associated with major labeled oral and dental AEs (ie, requiring labeling in warnings and precautions or boxed warnings). To the authors’ knowledge, such comprehensive descriptive information was not available previously.</div></div>","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"156 8","pages":"Pages 638-648.e6"},"PeriodicalIF":3.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144767250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient values and preferences: A path for better shared decision making.","authors":"Julia Pimentel, Alonso Carrasco-Labra, Lyubov Lytvyn, Abdullah Alalyani, Michael Glick","doi":"10.1016/j.adaj.2025.05.014","DOIUrl":"https://doi.org/10.1016/j.adaj.2025.05.014","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144649726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Developments in dental licensure examinations: A critical review.","authors":"Robert Bowers, Michael Kanellis","doi":"10.1016/j.adaj.2025.05.017","DOIUrl":"https://doi.org/10.1016/j.adaj.2025.05.017","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144649725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What dentists need to know about new guidelines for the treatment of patients with prosthetic joints.","authors":"Thomas M Paumier, Peter B Lockhart, Bryan Springer, Martin H Thornhill","doi":"10.1016/j.adaj.2025.05.013","DOIUrl":"https://doi.org/10.1016/j.adaj.2025.05.013","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144649727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fostering commitment to diverse perspectives in oral and maxillofacial surgery.","authors":"Yohana Fasel, Briana Burris","doi":"10.1016/j.adaj.2025.06.001","DOIUrl":"https://doi.org/10.1016/j.adaj.2025.06.001","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The silent decline of US dentistry: A global perspective.","authors":"Joe Iwanaga","doi":"10.1016/j.adaj.2025.06.002","DOIUrl":"https://doi.org/10.1016/j.adaj.2025.06.002","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maxillary and mandibular jaw enlargement.","authors":"Malak Alhadlaq, AlJoharah AlShathry, Asma Almunaye, Najla Alharbi, Reema Alhaidari, Reema Alsubaie, Piamkamon Vacharotayangul","doi":"10.1016/j.adaj.2025.05.010","DOIUrl":"https://doi.org/10.1016/j.adaj.2025.05.010","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":" ","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Directory","authors":"","doi":"10.1016/S0002-8177(25)00300-9","DOIUrl":"10.1016/S0002-8177(25)00300-9","url":null,"abstract":"","PeriodicalId":17197,"journal":{"name":"Journal of the American Dental Association","volume":"156 7","pages":"Page A16"},"PeriodicalIF":3.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}