Journal of Surgical Oncology最新文献_第9页

A Single Institution Experience With Immediate Lymphatic Reconstruction: Impact of Insurance Coverage on Risk Reduction. 单一机构的经验与即时淋巴重建：保险覆盖对风险降低的影响。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-29 DOI: 10.1002/jso.28067

Anne Huang, Emma Koesters, Rebecca M Garza, Summer E Hanson, David W Chang

{"title":"A Single Institution Experience With Immediate Lymphatic Reconstruction: Impact of Insurance Coverage on Risk Reduction.","authors":"Anne Huang, Emma Koesters, Rebecca M Garza, Summer E Hanson, David W Chang","doi":"10.1002/jso.28067","DOIUrl":"https://doi.org/10.1002/jso.28067","url":null,"abstract":"Background and objectives: Immediate lymphatic reconstruction (ILR) performed to prevent breast cancer related lymphedema is not consistently covered by insurance payors in the United States.Methods: Retrospective review was performed on a prospective database of ILR candidates from 2018 to 2022. Candidates were identified as patients with clinical axillary lymph node involvement at the time of breast cancer diagnosis. Patient demographics, insurance type, and development of lymphedema were recorded.Results: One hundred and eighty ILR candidates were identified, 50 of whom underwent ILR. Non-ILR patients were more likely to be of black race, have Medicaid health insurance, earn lower median household income, and have lower rates of out-of-pocket payment when not covered by insurance. In 40 cases where ILR was indicated but not performed, 55% were due to financial reasons. After a minimum of 1 year follow up, 14.6% (6/41) of patients who underwent ILR had lymphedema, compared with 12.5% (9/72) of patients who had no clinical indication for ILR and 40% (10/25) of patients who did not undergo ILR when clinically indicated (p = 0.012).Conclusions: Disparities in insurance coverage and financial resources may adversely impact access and outcomes in patients clinically indicated for ILR.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Racial Disparities in the Use of Minimally Invasive Surgery for Gastrointestinal Cancer. 胃肠癌微创手术应用的种族差异。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-29 DOI: 10.1002/jso.28051

Andrei Gurau, Olivia Monton, Jonathan B Greer, Norman G Nicolson, Fabian M Johnston

{"title":"Racial Disparities in the Use of Minimally Invasive Surgery for Gastrointestinal Cancer.","authors":"Andrei Gurau, Olivia Monton, Jonathan B Greer, Norman G Nicolson, Fabian M Johnston","doi":"10.1002/jso.28051","DOIUrl":"https://doi.org/10.1002/jso.28051","url":null,"abstract":"Introduction: Racial disparities in minimally invasive surgery (MIS) utilization across gastrointestinal (GI) cancers are not well characterized. We evaluated racial/ethnic disparities in the use of MIS approaches and associated outcomes.Methods: We analyzed a cohort of patients with GI cancer in the National Cancer Database (2010-2020). Multinomial logistic regression was used to evaluate associations between race/ethnicity and approach. Logistic regression was used to assess 30-day readmission and 90-day mortality. Cox regression was used to analyze overall survival. Models were adjusted for demographics, clinical characteristics, cancer factors, and facility features.Results: Of the 839 398 patients included, 76.9% were White, 11.6% Black, 6.6% Hispanic/Latino, 4.0% Asian, and 0.3% Indigenous. Compared with patients of White race, the odds of robotic surgery were lower for Black (OR 0.89, 95% CI 0.86-0.93) and Indigenous patients (OR 0.72, 95% CI 0.59-0.89), but higher for Hispanic/Latino (OR 1.12, 95% CI 1.08-1.17) and Asian patients (OR 1.27, 95% CI 1.21-1.34). Indigenous patients had higher odds of readmission (OR 1.41, 95% CI 1.23-1.62), 90-day mortality (OR 1.31, 95% CI 1.11-1.54), and worse overall survival (HR 1.11, 95% CI 1.05-1.18).Conclusion: Indigenous and Black patients have lower utilization of minimally invasive approaches and worse outcomes in GI cancer care.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recommendations of the Brazilian Society of Surgical Oncology for the Treatment of Neoplastic Pericardial Effusion. 巴西肿瘤外科学会治疗肿瘤性心包积液的建议。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-29 DOI: 10.1002/jso.28059

Erlon de Avila Carvalho, Rachid Eduardo Noleto da Nobrega Oliveira, José Henrique Agner Ribeiro, Jefferson Luís Gross, Cezar Augusto Vendas Galhardo, Heládio Feitosa E Castro Neto, Giovana Dos Santos, Reitan Ribeiro, Alexandre Ferreira Oliveira, Rodrigo Nascimento Pinheiro

引用次数: 0

Outcomes of Minimally Invasive Rectal Cancer Resection: Insights From a Resource-Limited Setting. 微创直肠癌切除术的结果：来自资源有限环境的见解。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-23 DOI: 10.1002/jso.28060

Abinaya R Nadarajan, Chandramohan Krishnan Nair, Madhu Muralee, Mira Sudam Wagh, Anoop T M, Preethi Sara George

{"title":"Outcomes of Minimally Invasive Rectal Cancer Resection: Insights From a Resource-Limited Setting.","authors":"Abinaya R Nadarajan, Chandramohan Krishnan Nair, Madhu Muralee, Mira Sudam Wagh, Anoop T M, Preethi Sara George","doi":"10.1002/jso.28060","DOIUrl":"https://doi.org/10.1002/jso.28060","url":null,"abstract":"Background: Minimally invasive approaches for rectal cancer treatment are emerging as the standard of care. Robotic surgery is unfeasible across the country due to constrained resource allocation. This study aimed to assess the oncologic efficacy of laparoscopic resection for rectal cancer in a resource-limited setting.Methods: A propensity score-matched analysis was carried out to compare the oncological outcomes of laparoscopic and open rectal cancer resection at a high-volume tertiary cancer centre in South India.Results: Two hundred and twenty patients were included (110 patients in each group). The median follow-up was 93 months. There was no difference in positive circumferential resection margin between laparoscopic and open group (4.5% vs. 6.4%, p = 0.55), with a significantly better nodal yield in laparoscopic group. There was no significant difference between the laparoscopic and open groups in terms of local recurrence (5.1% vs. 8.3%, p = 0.12), 5-year disease-free survival (86% vs. 81%, p = 0.22, HR 0.699, 95% CI 0.353-1.27) or overall survival (85% vs. 76%, p = 0.21, HR 0.658, 95% CI 0.340-1.27). The mean cost between the two groups had no difference.Conclusion: In a resource-limited setting with good expertise, laparoscopic surgery is an effective minimally invasive option that has good survival outcomes without imposing a financial burden on patients.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the Role of Surgical Resection and Reconstruction in the Management of Ewing sarcoma of the Chest Wall in the Paediatric Population: A Systematic Review. 评估手术切除和重建在儿科胸壁尤文氏肉瘤治疗中的作用：一项系统综述。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-22 DOI: 10.1002/jso.28053

Darragh Rice, Seán Barrett, Naomi Lavan, Patricia Daly, Cormac Owens, Jane Pears, Michael Capra, Jonathan McGuinness

{"title":"Evaluating the Role of Surgical Resection and Reconstruction in the Management of Ewing sarcoma of the Chest Wall in the Paediatric Population: A Systematic Review.","authors":"Darragh Rice, Seán Barrett, Naomi Lavan, Patricia Daly, Cormac Owens, Jane Pears, Michael Capra, Jonathan McGuinness","doi":"10.1002/jso.28053","DOIUrl":"https://doi.org/10.1002/jso.28053","url":null,"abstract":"Background and objectives: Ewing sarcoma is the most common malignant chest wall tumour in the paediatric population. Following neoadjuvant chemotherapy regimens, the role and extent of surgical resection and reconstruction of the chest wall remain unclear.Methods: A systematic review was conducted in accordance with PRISMA guidelines across four major literature databases. Data regarding overall survival, rate of recurrence, role of surgery and adjuvant therapy role was extracted.Results: Three thousand ninety-one studies were initially identified via the search, with 25 single-centre observational studies (458 patients) and 10 retrospective reviews of multicentre trials (961 patients) included in the final analysis. Five-year overall survival ranged from 35% to 90%.Discussion: Along with chemotherapy, local control with surgical resection provides the cornerstone of the management of Ewing sarcoma of the chest wall in children. The literature favours delaying surgery until after neoadjuvant chemotherapy, and there appear to be limited benefits to extensive resection according to pre-chemotherapy margins, advocated for in current guidelines. Radiotherapy is no longer advocated for all patients, but rather should be guided by surgical margins and the histological response to chemotherapy in the resected specimens. Surgical reconstructive techniques need to be tailored for the growth potential of these paediatric patients to avoid long-term sequalae, including scoliosis and pulmonary restrictive disease.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New Onset Diabetes in Pancreatic Adenocarcinoma Does Not Correlate With Molecular Subtype. 胰腺腺癌新发糖尿病与分子亚型无关

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-22 DOI: 10.1002/jso.28044

Hannah E Trembath, Michelle E LaBella, Joseph F Kearney, Arthi Hariharan, Sandra Zarmer, Mariaelena Nabors, Ian McCabe, Ryan T Zhao, Michael Meyers, Hong Jin Kim, Jen Jen Yeh

{"title":"New Onset Diabetes in Pancreatic Adenocarcinoma Does Not Correlate With Molecular Subtype.","authors":"Hannah E Trembath, Michelle E LaBella, Joseph F Kearney, Arthi Hariharan, Sandra Zarmer, Mariaelena Nabors, Ian McCabe, Ryan T Zhao, Michael Meyers, Hong Jin Kim, Jen Jen Yeh","doi":"10.1002/jso.28044","DOIUrl":"https://doi.org/10.1002/jso.28044","url":null,"abstract":"Background and objectives: Studies show that new onset diabetes mellitus (DM) (NOD) predates the diagnosis of PDAC by up to 2 years. Two tumor-intrinsic molecular subtypes of PDAC that are prognostic and predictive of chemotherapy response have been described and validated. We hypothesize that patients with NOD may have different molecular subtypes and prognoses.Methods: This is a single-institution study of patients who underwent resection for PDAC from 2009 to 2022 with de-identified samples available for sequencing. Demographic and clinical factors were examined using bivariate and multivariate analysis.Results: A total of 97 patients met inclusion criteria: 70 with no history of DM, 11 with longstanding DM (> 2 years), and 16 with NOD. The demographics between groups were overall similar. After controlling for age, sex, race, BMI, and tobacco history, NOD was not a significant predictor of PDAC subtype. There were no survival differences between groups. Transcriptomic analysis suggests the upregulation of inflammatory and immune activation and regulation pathways in NOD.Conclusions: As continued interest in NOD and PDAC mounts, we are the first to examine if NOD may be associated with molecular subtypes and outcomes. Further investigation into the underlying pathophysiology of the NOD group is still needed.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing Patient Decision-Making in Breast Reconstruction: A Systematic Review of Decision Aid Efficacy. 增强乳房重建患者决策：辅助决策效果的系统综述。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-22 DOI: 10.1002/jso.28038

Francis D Graziano, Donovan R White, Ethan L Plotsker, Ronnie L Shammas, Elizabeth Smith-Montes, Jonas A Nelson, Carrie S Stern

{"title":"Enhancing Patient Decision-Making in Breast Reconstruction: A Systematic Review of Decision Aid Efficacy.","authors":"Francis D Graziano, Donovan R White, Ethan L Plotsker, Ronnie L Shammas, Elizabeth Smith-Montes, Jonas A Nelson, Carrie S Stern","doi":"10.1002/jso.28038","DOIUrl":"https://doi.org/10.1002/jso.28038","url":null,"abstract":"Background: Patients often struggle to select a breast reconstruction option that aligns with their personal values. Decision aids have become popular tools to assist patients in navigating these choices. This systematic review assesses the effectiveness of available breast reconstruction decision aids.Methods: We conducted a comprehensive search across five databases from inception to December 2022, identifying studies related to the development, validation, or implementation of decision aids in breast reconstruction.Results: Out of 4621 reports, 24 studies met inclusion criteria, covering 14 unique decision aids. These included 13 randomized controlled trials, 9 qualitative studies, and 2 case series. Nine studies reported reduced decisional conflict and 2 studies showed decreased decisional regret. Additionally, 13 studies found improved satisfaction with the information provided, and all seven studies that measured knowledge retention showed improvements. However, none of the studies found a reduction in anxiety or depression following the use of decision aids.Conclusions: Decision aids are effective in reducing decisional conflict, enhancing patient satisfaction, and improving knowledge retention in breast reconstruction. Future research should focus on integrating these tools into clinical practice.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142877154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Term Quality of Life and Survivorship Priorities in Esophageal Cancer Patients: A Survey-Based Assessment. 食管癌患者的长期生活质量和生存优先权：一项基于调查的评估。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-19 DOI: 10.1002/jso.28045

Edward A Joseph, Casey J Allen

{"title":"Long-Term Quality of Life and Survivorship Priorities in Esophageal Cancer Patients: A Survey-Based Assessment.","authors":"Edward A Joseph, Casey J Allen","doi":"10.1002/jso.28045","DOIUrl":"https://doi.org/10.1002/jso.28045","url":null,"abstract":"Background and objectives: This study examines the long-term quality of life (QOL) and priorities of survivors who underwent management for esophageal cancer (EC).Methods: We cross-sectionally surveyed EC patients through online support groups to assess the relative importance of their overall survival, experience, costs of care, and QOL. Kendall's co-efficient of Concordance (W) was utilized to assess agreement among respondents.Results: Among 100 respondents (age 57.2 ± 10.4 years, 54% male, 90% Caucasian), median overall survival was 18.0 (7.8-49.8) months, with a maximum survivorship of 48.3 years. Respondents ranked overall survival most important, followed by functional independence, emotional well-being, treatment experience, and costs of care (W = 0.342, p < 0.001). Some survivors ranked treatment experience (4%) or costs (6%) as their most important priority. The cohort's physical QOL (P-QOL; 39.79 ± 10.16) and mental QOL (M-QOL; 42.29 ± 15.43) were below that of the general population (50.00 ± 10.00); both p < 0.050. There was no difference in P-QOL and M-QOL based on the presence of metastatic disease (both p > 0.050). Patients who underwent curative surgery had superior M-QOL (45.00 ± 15.22 vs. 36.70 ± 14.53, p = 0.010). Although P-QOL was similar based on duration of survival (40.30 ± 9.75 [< 1 year], 39.33 ± 10.52 [1-5 years], 39.81 ± 10.68 [> 5 years], p = 0.873), M-QOL was higher in patients with extended survivorship (36.87 ± 14.24 [< 1 year], 45.05 ± 14.94 [1-5 years], 47.30 ± 16.36 [> 5 years], p = 0.008).Conclusions: Despite enduring physical health impairments, a majority of EC survivors prioritized their survival. However, a few survivors prioritized costs and treatment experience, underscoring the importance of tailoring treatments to ensure alignment with individual patient-driven priorities.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the Editor: Reporting of Core Outcomes in Gastric Cancer Surgical Trials Over the Past 25 Years (Systematic Review). 致编辑的信：过去25年胃癌手术试验的核心结果报告（系统评价）。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-19 DOI: 10.1002/jso.28057

Alice Zhu, Ekaterina Kosyachkova, Teresa Tiano, Natalie G Coburn

引用次数: 0

Collagen Density Is Associated With Pathological Complete Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer Patients. 胶原蛋白密度与三阴性乳腺癌患者新辅助化疗病理完全反应相关

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-19 DOI: 10.1002/jso.28046

Fengling Li, Yani Wei, Li Li, Fei Chen, Chunjuan Bao, Hong Bu, Zhang Zhang

{"title":"Collagen Density Is Associated With Pathological Complete Response to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer Patients.","authors":"Fengling Li, Yani Wei, Li Li, Fei Chen, Chunjuan Bao, Hong Bu, Zhang Zhang","doi":"10.1002/jso.28046","DOIUrl":"https://doi.org/10.1002/jso.28046","url":null,"abstract":"Background and objectives: The tumor-associated stroma is an essential compartment in breast cancer, and collagen fiber organization in the stroma has been reported to be correlated with prognosis. In this study, we sought to evaluate collagen fiber characteristics in relation to pathological complete response (pCR) after neoadjuvant chemotherapy (NAC) in breast cancer patients.Methods: A total of 388 breast cancer patients receiving NAC were enrolled. The stroma type was manually assessed on pretreatment hematoxylin and eosin (HE)-stained slides, and the collagen fiber features were quantified by a computer tool. The relationship between syndecan-1 expression and collagen fibers and its correlation with treatment efficacy were detected by immunohistochemistry.Results: The pCR rate of patients with collagen-dominant stroma was lower than that of patients with lymphocyte-dominant stroma (19.6% vs. 40.0%, p = 0.001). Patients who achieved pCR had straighter and less dense fibers in pretreatment biopsied tissue than non-pCR patients (p = 0.031, p = 0.044). Additionally, the pCR group had greater syndecans-1 expression on the tumor epithelium than the non-pCR group (p < 0.001), while there was no statistically significant difference in the stroma (p = 0.333). Collagen fiber density was the only factor associated with pCR after correction for other clinicopathological variables in triple-negative breast cancer (TNBC) patients (OR 0.466, 95% CI 0.227-0.956, p = 0.037); patients with lower fiber density had a greater pCR rate (37.5% vs. 12.5%, p = 0.021).Conclusions: Collagen fiber density was associated with pCR in patients with breast cancer, and it could be a potential candidate for discriminating between responders and nonresponders for TNBC patients receiving NAC.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0