Journal of Surgical Oncology最新文献

{"title":"Techniques in Robotic Pancreatic Reconstruction for Pancreaticoduodenectomy: Tailoring Approaches to Different Situations","authors":"Thiago Costa Ribeiro,&nbsp;Lucas Cata Preta Stolzemburg,&nbsp;Francisco Tustumi,&nbsp;Ricardo Jureidini,&nbsp;Estela Regina Ramos Figueira,&nbsp;José Jukemura,&nbsp;Paulo Herman,&nbsp;Ulysses Ribeiro Júnior,&nbsp;Guilherme Naccache Namur","doi":"10.1002/jso.28114","DOIUrl":"10.1002/jso.28114","url":null,"abstract":"<div>\u0000 \u0000 <p>This “How I Do It” study provides an in-depth exploration of techniques for pancreatic reconstruction following pancreaticoduodenectomy. The study includes a video demonstration highlighting the step-by-step strategies and appropriate indications for each reconstruction method using the robotic system.</p></div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"131 7","pages":"1467-1471"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Detection of Local Recurrence After Rectal Cancer Resection in Asymptomatic Patients Is Essential for Survival","authors":"Katharina Esswein,&nbsp;Eva Hummer,&nbsp;Marijana Ninkovic,&nbsp;Elisabeth Gasser,&nbsp;Veronika Kröpfl,&nbsp;Reinhold Kafka-Ritsch","doi":"10.1002/jso.28120","DOIUrl":"10.1002/jso.28120","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Objectives</h3>\u0000 \u0000 <p>Despite advancements in rectal cancer treatment, therapy of local recurrence remains a significant challenge as it has to be individualized to the extent of recurrence and prior treatment. This study aims to analyze outcomes of patients with local recurrence after resection for rectal cancer, focusing on R0-resection rates and overall survival (OS).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective cohort study included 31 patients with local recurrence after initial curative resection for rectal cancer between 2003 and 2021.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Recurrence was diagnosed in 77.4% of cases during scheduled routine follow-up and 58,1% of patients reported of symptoms at the time of diagnosis. Symptomatic patients tended to be treated palliatively (66.7%, 12/18, <i>p</i> = 0.073). A curative treatment approach was intended in 48.4% of all patients, with 80% achieving R0-resection by surgery. The 5-year OS was significantly longer in patients achieving R0-resection (58.3% vs. 5.3%, <i>p</i> = 0.0) and decreased in symptomatic patients (11.1% vs. 46.2%, <i>p</i> = 0.025).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>These findings emphasize the importance of early recurrence detection, optimally in a scheduled cancer follow-up.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"131 8","pages":"1637-1641"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robot-Assisted Versus Open Radical Cystectomy: Comparison of Adverse In-Hospital Outcomes","authors":"Francesco Di Bello,&nbsp;Natali Rodriguez Peñaranda,&nbsp;Andrea Marmiroli,&nbsp;Mattia Longoni,&nbsp;Fabian Falkenbach,&nbsp;Quynh Chi Le,&nbsp;Zhe Tian,&nbsp;Jordan A. Goyal,&nbsp;Claudia Collà Ruvolo,&nbsp;Gianluigi Califano,&nbsp;Massimiliano Creta,&nbsp;Fred Saad,&nbsp;Shahrokh F. Shariat,&nbsp;Stefano Puliatti,&nbsp;Ottavio De Cobelli,&nbsp;Alberto Briganti,&nbsp;Markus Graefen,&nbsp;Felix H. K. Chun,&nbsp;Nicola Longo,&nbsp;Pierre I. Karakiewicz","doi":"10.1002/jso.28108","DOIUrl":"10.1002/jso.28108","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To quantify improvements in adverse in-hospital outcomes between historical and contemporary robot-assisted radical cystectomy (RARC) versus historical and contemporary open RC (ORC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Within the National Inpatient Sample (2010–2019), RARC and ORC ileal conduit diversion patients were identified. Multivariable logistic and Poisson regression models were fitted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of RARC patients, 1343 (39%) were historical (2010–2014) and 2087 (61%) were contemporary (2015–2019). Of ORC patients, 5812 (54%) were historical and 5019 (46%) were contemporary. Versus historical counterparts, contemporary RARC patients exhibited significantly better adverse in-hospital outcomes in 9 of 13 categories, with improvements ranging from −82% for intraoperative complications to −22% for cumulative postoperative complications. Similarly, versus historical, contemporary ORC patients also exhibited significantly better adverse in-hospital outcomes in 9 of 13 categories, with improvements ranging from −72% for intraoperative complications to −12% for median length of stay (LOS). When contemporary RARC was compared to contemporary ORC, RARC adverse in-hospital outcomes were better in 7 of 13 comparisons, with improvements ranging from −55% for blood transfusions to −18% for median LOS. Similarly, when historical RARC was compared to historical ORC, RARC adverse in-hospital outcomes were better in 6 of 13 comparisons, with improvements ranging from −55% for blood transfusions to −15% for median LOS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The magnitude of the improvement in adverse in-hospital outcomes was comparable between contemporary versus historical RARC (nine improved categories) and contemporary versus historical ORC (nine improved categories). However, contemporary RARC outperformed contemporary ORC in 7 of 13 categories of adverse in-hospital outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"131 8","pages":"1651-1660"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrence and Survival Following Robotic Resection of Thymomas Greater Than Five Centimeters","authors":"John M. Campbell,&nbsp;Peter T. White,&nbsp;Adam J. Bograd,&nbsp;Alexander S. Farivar,&nbsp;Candice L. Wilshire,&nbsp;Eric Vallières,&nbsp;Brian E. Louie","doi":"10.1002/jso.28098","DOIUrl":"10.1002/jso.28098","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background and Methods</h3>\u0000 \u0000 <p>Minimally invasive large thymoma resection remains controversial given the paucity of long-term oncological outcomes. We described the recurrence and survival of patients with thymomas ≥ 5 cm resected robotically.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Consecutive thymoma resections between January 2006 and December 2022 were reviewed. Thymic carcinoma/neuroendocrine tumors, induction therapy treatment, and Stage IV disease were excluded. For thymomas ≥ 5 cm, open versus robotic resections were compared. With robotic resections, thymomas ≥/&lt; 5 cm were compared. The outcomes were freedom from recurrence (FFR) and overall survival (OS).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There were 40 thymomas ≥ 5 cm (15 open and 25 robotic) and 52 robotic thymoma &lt; 5 cm resections. Median follow-up was 5 years with 4 (4%) patients having recurrences and 5 (5%) demised.</p>\u0000 \u0000 <p>In thymomas ≥ 5 cm, patients were similar, except for higher comorbidities in the open cohort. Five-year FFR (<i>p</i> = 0.42) and OS (<i>p</i> = 0.34) were comparable.</p>\u0000 \u0000 <p>Patients with robotic resection of thymomas ≥/&lt; 5 cm were similar, except those &lt; 5 cm were more frequently Masaoka−Koga Stage II. Five-year FFR (<i>p</i> = 0.62) and OS (<i>p</i> = 0.62) were similar.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Resectable large thymomas, ≥ 5 cm, can be approached robotically with similar recurrence and survival when compared to open or smaller robotic resections. In otherwise appropriate thymomas, considerations such as location and proximity to surrounding structures, over size alone, should guide the approach.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"131 8","pages":"1521-1528"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robot-Assisted Versus Open Surgery for the Resection of Large Thymomas: A Retrospective Cohort Study","authors":"Benedikt Niedermaier,&nbsp;Raffaella Griffo,&nbsp;Florian Eichhorn,&nbsp;Laura V. Klotz,&nbsp;Heidrun Grosch,&nbsp;Thomas Muley,&nbsp;Hauke Winter,&nbsp;Martin E. Eichhorn","doi":"10.1002/jso.28113","DOIUrl":"10.1002/jso.28113","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Robot-assisted thoracic surgery (RATS) is increasingly becoming the preferred surgical method for the resection of thymomas. We initiated the current study to evaluate perioperative outcomes and early recurrence associated with the surgical approach.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this retrospective cohort study, 35 patients were included in the RATS group and compared with 29 patients who underwent open surgery between 2010 and 2022 for histologically confirmed large thymoma &gt; 50 mm in TNM Stages I, II, and IIIa.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Histologic subtypes and pathologic stages were similar in both groups. The median duration of chest drainage and median length of stay was significantly shorter in the RATS group (1 vs. 4 days, <i>p</i> &lt; 0.0001, and 4 vs. 10 days, <i>p</i> &lt; 0.0001, respectively). Postoperative complications occurred more frequently in the open surgery group (cumulative incidence of 8.6% vs. 37.9%, <i>p</i> = 0.0048). The median follow-up time was 28 months in the RATS group and 69 months in the open surgery group. Five-year recurrence-free survival was 96.9% without significant differences between the two groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>There is no evidence of increased early recurrence associated with robotic surgery. The length of hospital stay, the duration of thoracic drainage, and the significantly lower complications favor the robot-assisted approach.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"131 8","pages":"1543-1550"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jso.28113","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Functional Outcomes of Glenohumeral Arthrodesis Following Oncologic Resection","authors":"Marisa N. Ulrich,&nbsp;Samuel E. Broida,&nbsp;Maurizio Scorianz,&nbsp;Steven L. Moran,&nbsp;Allen T. Bishop,&nbsp;Matthew T. Houdek","doi":"10.1002/jso.28117","DOIUrl":"10.1002/jso.28117","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Glenohumeral arthrodesis is a demanding surgical procedure. However, it is an option for reconstruction an oncologic resection, especially for patients in whom the axillary nerve is compromised.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We reviewed 26 (12 male:14 female) glenohumeral arthrodeses (14 primary:12 revision) following an oncologic resection. The most common method of reconstruction was a free vascularized fibula autograft with a bulk allograft (<i>n</i> = 18). The median follow-up was 22 years (IQR 19 years).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Median Musculoskeletal Tumor Society Scores and Toronto Extremity Salvage Scores at final follow-up were 86% and 80%. MSTS scores were similar in patients receiving arthrodesis for primary versus secondary reconstruction. Fifteen (58%) patients had postoperative complications requiring reoperation. Most reoperations occurred with-in the first 5 years postoperative, with two procedures occurring after 10-years. Three patients were diagnosed with metastatic disease, one of which also had a local recurrence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Glenohumeral arthrodesis provides satisfactory long-term outcomes for primary and secondary management of shoulder girdle tumors. While early complication rates were high, long-term complications were rare.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"131 8","pages":"1696-1701"},"PeriodicalIF":2.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Association of Socio-Environmental Burden and Inequality With Cancer Screening and Mortality\".","authors":"Wei Liu, Yuwei Yang","doi":"10.1002/jso.28122","DOIUrl":"https://doi.org/10.1002/jso.28122","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Challenging Oncologic Cases: A Comparative Analysis Between ChatGPT, Gemini, and a Multidisciplinary Tumor Board","authors":"Luis A. Hernández-Flores,&nbsp;José B. López-Martínez,&nbsp;Jesús J. Rosales-de-la-Rosa,&nbsp;Daniel Aillaud-De-Uriarte,&nbsp;Sergio Contreras-Garduño,&nbsp;Rubén Cortés-González","doi":"10.1002/jso.28121","DOIUrl":"10.1002/jso.28121","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Since its introduction in 2022, public-access conversational AI, exemplified by ChatGPT and Gemini, has been increasingly utilized in medical decision-making, though its impact is questionable. This study aims to evaluate its efficacy in assessing complex oncologic cases compared to a multidisciplinary tumor board (MTB) comprising experts from various specialties.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A 2-year retrospective analysis was conducted on 98 oncological cases at a reference medical center in Mexico City. A MTB comprising surgical oncologists, medical oncologists, radio-oncologists, pathologists, among others, reviewed and discussed each case to determine management strategies. We evaluated four key decision points, dichotomized as either affirmative or negative: the need for new imaging studies, radiation therapy, chemotherapy, and surgery. Comprehensive medical documentation accompanied each case. We then compared AI's decisions with those of the MTB using the same criteria and conducted a Cohen's Kappa test to assess agreement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Agreement between ChatGPT (4o) and Gemini (1.5 Flash), and the MTB ranged from none to slight for additional imaging studies (Gemini: <i>κ</i> = 0.100, <i>p</i> = 0.087; ChatGPT 4o: <i>κ</i> = 0.024, <i>p</i> = 0.592) and chemotherapy (Gemini: <i>κ</i> = 0.089, <i>p</i> = 0.316; ChatGPT 4o: <i>κ</i> = 0.336, <i>p</i> = 0.001). Moderate agreement was observed for decisions regarding surgery (Gemini: <i>κ</i> = 0.194, <i>p</i> = 0.046; ChatGPT 4o: <i>κ</i> = 0.467, <i>p</i> = &lt; 0.001) and radiotherapy (Gemini: <i>κ</i> = 0.214, <i>p</i> = 0.012; ChatGPT 4o: <i>κ</i> = 0.525, <i>p</i> = &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Both ChatGPT and Gemini showed moderate agreement with the multidisciplinary tumor board on decisions regarding surgery and radiotherapy. ChatGPT also showed moderate agreement in chemotherapy, but further assessment is needed for other interventions. ChatGPT proved to be superior to Gemini in most key points. The potential of these public access AI in oncology warrants continued exploration to refine its utility in clinical practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":"131 8","pages":"1562-1570"},"PeriodicalIF":2.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Lymph Node Dissection for Melanoma: Contemporary Trends in Postoperative Outcomes and Patient Selection With Reduced Case Volumes in the Post-MSLT2 Era\".","authors":"Wei Liu, Yuwei Yang","doi":"10.1002/jso.28118","DOIUrl":"https://doi.org/10.1002/jso.28118","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implications of Artificial Intelligence for Colorectal Cancer: Correspondence.","authors":"Amnuay Kleebayoon, Viroj Wiwanitkit","doi":"10.1002/jso.28062","DOIUrl":"https://doi.org/10.1002/jso.28062","url":null,"abstract":"","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}