Journal of Surgical Oncology最新文献_第8页

Predictors Based on the Radiologic Characteristics for Aggressiveness of Small (< 20 mm) Nonfunctioning Pancreatic Neuroendocrine Tumors. 基于小（< 20mm）无功能胰腺神经内分泌肿瘤侵袭性放射学特征的预测因素。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-19 DOI: 10.1002/jso.28049

Shu-Jie Ren, Fan Yang, Qing-Quan Tan, Chang Liu, Xu-Bao Liu, Chun-Lu Tan, Xing Wang

{"title":"Predictors Based on the Radiologic Characteristics for Aggressiveness of Small (< 20 mm) Nonfunctioning Pancreatic Neuroendocrine Tumors.","authors":"Shu-Jie Ren, Fan Yang, Qing-Quan Tan, Chang Liu, Xu-Bao Liu, Chun-Lu Tan, Xing Wang","doi":"10.1002/jso.28049","DOIUrl":"https://doi.org/10.1002/jso.28049","url":null,"abstract":"Background and objectives: To find the association between preoperative computed tomography (CT) features combined with tumor marker and known high-risk factors of small nonfunctioning pancreatic neuroendocrine tumors (NF-PNETS), thereby selecting appropriate treatment strategy for these patients.Method: One hundred fourteen patients with NF-PNETs< 20 mm who underwent surgical operation were retrospectively analyzed from 2009 to 2023. Univariate and multivariable logistic regression analyses were performed to find the relationship between preoperative clinical psychological and CT features and high-risk factors. The overall survival (OS) rates with and without high-risk factors were compared.Results: Of 114 patients, 29(25%) had at least one of these high-risk factors. Main pancreatic duct dilation (OR, 3.315; 95% CI, 1.079-10.184; p = 0.036), irregular tumor margin (OR, 2.955; 95% CI, 1.021-8.551; p = 0.046), positive tumor marker (OR, 6.047; 95% CI, 1.408-25.963; p = 0.015) were associated with increased odds of having any of these high-risk factors. The time to death differed significantly between patients with and without high-risk factors. Patients combining with high-risk factors were associated with lower 3- and 5-year OS (100% vs. 81.8%, 93.1% vs. 81.8%, respectively; p = 0.035 for both).Conclusion: Main pancreatic duct dilation, irregular tumor margin and positive tumor marker could screen a subset of patients recommended for surgery.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142864615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to "Body Mass Index and Breast Cancer-Related Lymphedema: A Retrospective Cohort Study". 致“体重指数与乳腺癌相关淋巴水肿：一项回顾性队列研究”的信。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-19 DOI: 10.1002/jso.28055

Xiaoyang Wang, Jiamei Jin, Yekang Zhu, Xiaogu Liu

引用次数: 0

Reply to "Comment on 'Prognostic Impact of the Cholangiolar Component in Combined Hepatocellular-Cholangiocarcinoma: Insights From a Western Single-Center Study'". 对“肝细胞-胆管合并癌中胆管成分对预后的影响：来自西方单中心研究的见解”的评论

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-18 DOI: 10.1002/jso.28056

Gilton Marques Fonseca, Paulo Herman

引用次数: 0

Patient and Surgeon Attitudes Toward Opportunistic Salpingectomy During Nongynecological Surgeries for the Prevention of Ovarian Cancer: A Qualitative Study. 患者和外科医生对预防卵巢癌的非妇科手术中机会性输卵管切除术的态度：定性研究。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-17 DOI: 10.1002/jso.28050

Carly C Tymm, Reena M Vattakalam, David R Flum, Jason D Wright, Katherine N Fischkoff

{"title":"Patient and Surgeon Attitudes Toward Opportunistic Salpingectomy During Nongynecological Surgeries for the Prevention of Ovarian Cancer: A Qualitative Study.","authors":"Carly C Tymm, Reena M Vattakalam, David R Flum, Jason D Wright, Katherine N Fischkoff","doi":"10.1002/jso.28050","DOIUrl":"https://doi.org/10.1002/jso.28050","url":null,"abstract":"Background and objectives: Opportunity salpingectomy (OS), or prophylactic removal of the fallopian tubes during an operation for another indication, is broadly accepted as a risk-reduction strategy for ovarian cancer during gynecological operations. However, OS during nongynecological abdominal surgery is rare in the United States. A better understanding of surgeon and patient attitudes and perceived barriers to OS during nongynecological surgeries may facilitate implementation in the United States.Study design: Qualitative interviews were conducted with general surgeons (n = 10), gynecologic surgeons (n = 10), and patients (n = 20) to assess perspectives and barriers towards OS during nongynecological surgeries. Interviews were transcribed and inductive analysis was carried out to identify themes and categorize responses using NVivo data analysis software.Results: OS during nongynecological surgery was viewed favorably by most patients and surgeons interviewed. While patients emphasized the importance of raising awareness of OS, both subsets of surgeons highlighted coordination, counseling, and billing barriers that would need to be overcome for efficient implementation.Conclusion: OS was positively accepted by both patients and surgeons in our cohort. Improved attention to the shared barriers to implementation from our study may facilitate OS implementation during nongynecological surgery in the United States.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Socio-Environmental Burden and Inequality With Cancer Screening and Mortality. 社会环境负担和不平等与癌症筛查和死亡率的关系。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-17 DOI: 10.1002/jso.28039

Shahzaib Zindani, Mujtaba Khalil, Zayed Rashid, Abdullah Altaf, Selamawit Woldesenbet, Timothy M Pawlik

{"title":"Association of Socio-Environmental Burden and Inequality With Cancer Screening and Mortality.","authors":"Shahzaib Zindani, Mujtaba Khalil, Zayed Rashid, Abdullah Altaf, Selamawit Woldesenbet, Timothy M Pawlik","doi":"10.1002/jso.28039","DOIUrl":"https://doi.org/10.1002/jso.28039","url":null,"abstract":"Background and objectives: Social and environmental injustice may influence accessibility and utilization of health resources, affecting outcomes of patients with cancer. We sought to assess the impact of socio-environmental inequalities on cancer screening and mortality rates for breast, colon, and cervical cancer.Methods: Data on cancer screening and environmental justice index social and environmental ranking (SER) was extracted from the CDC PLACES and ATSDR, respectively. Mortality rates were extracted using CDC WONDER. Screening targets were defined by Healthy People 2030.Results: Among census tracts, 14 659 were classified as \"low,\" 29 534 as \"moderate,\" and 15 474 as \"high\" SER (high SER denoting greater socioenvironmental injustice). Screening targets were achieved by 31.1%, 16.2%, and 88.6% of tracts for colon, breast, and cervical cancers, respectively. High SER tracts were much less likely to reach screening targets compared with low SER tracts for colon (OR: 0.06), breast (OR: 0.24), and cervical cancer (OR: 0.05) (all p < 0.001). Median mortality rates for low and high SER were 16.7, and 21.0, respectively, for colon, 13.4, 14.75, respectively, for breast, and 1.0, 1.6, respectively, for cervical cancer (all p < 0.05).Conclusion: Socioenvironmental disparities negatively influence cancer screening and mortality, underscoring the need to reduce environmental injustices through measures like equitable cancer screening services.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment On: "Assessment of Artificial Intelligence Chatbot Responses to Common Patient Questions on Bone Sarcoma". 评论："人工智能聊天机器人对骨肉瘤常见患者问题的回应评估"。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-17 DOI: 10.1002/jso.28052

Mengyang Zhang, Xiao Ye

引用次数: 0

De-Escalating Surgery in Merkel Cell Carcinoma With Clinical Nodal Disease. 对有临床结节病的梅克尔细胞癌进行去鳞手术

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-15 DOI: 10.1002/jso.28037

Neha Shafique, Emily Ertmann, Gabriella N Tortorello, Cimarron E Sharon, Giorgos C Karakousis, John T Miura

{"title":"De-Escalating Surgery in Merkel Cell Carcinoma With Clinical Nodal Disease.","authors":"Neha Shafique, Emily Ertmann, Gabriella N Tortorello, Cimarron E Sharon, Giorgos C Karakousis, John T Miura","doi":"10.1002/jso.28037","DOIUrl":"https://doi.org/10.1002/jso.28037","url":null,"abstract":"Background: Merkel cell carcinoma (MCC) is a radiosensitive aggressive skin cancer that spreads via the lymphatics. There is uncertainty regarding the optimal management of the nodal basin for patients with MCC with clinically positive nodes. We study the efficacy of single node excision (SNE) as an alternative to a therapeutic lymph node dissection (TLND) in patients with limited nodal disease.Methods: We performed a retrospective cohort study of patients with MCC with clinical nodal disease who underwent resection in the form of either SNE or TLND using the National Cancer Database. The association between type of surgery and overall survival (OS) was estimated using the Kaplan-Meier method and Cox proportional hazards modeling.Results: 1835 patients met all inclusion criteria with 281 patients undergoing SNE and the remainder undergoing TLND. Patients receiving SNE and TLND were equally likely to receive radiation to the nodal basin (SNE 44.5% vs. TLND 48.5%, p = 0.22). There was no difference in 5-year OS between patients who received SNE versus TLND (SNE 43.9% vs. TLND 44.7%, p = 0.36). This persisted in a multivariable Cox proportional hazards model in which receipt of SNE remained not significantly associated with survival after adjusting for clinical and treatment factors including receipt of radiation (Hazard Ratio [HR] 1.17, 95% CI 0.96-1.42, p = 0.11). In patients undergoing SNE with radiation, 5-year OS was 54.4% (95% CI 44.1-63.6).Conclusions: TLND is not associated with a survival advantage over SNE. Further prospective study into patterns of recurrence and safety of SNE is needed.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Pulmonary Metastasectomy for Non-Primary Lung Cancer: Umbrella Review of Meta-Analyses. 非原发性肺癌肺转移切除术的作用：Meta分析综述。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-15 DOI: 10.1002/jso.28033

Wongi Woo, Brandon Park, Awranoos Ahadi, Liam Il-Young Chung, Chan Mi Jung, Ankit Bharat, Young Kwang Chae

{"title":"The Role of Pulmonary Metastasectomy for Non-Primary Lung Cancer: Umbrella Review of Meta-Analyses.","authors":"Wongi Woo, Brandon Park, Awranoos Ahadi, Liam Il-Young Chung, Chan Mi Jung, Ankit Bharat, Young Kwang Chae","doi":"10.1002/jso.28033","DOIUrl":"https://doi.org/10.1002/jso.28033","url":null,"abstract":"Background and objectives: Due to heterogeneous characteristics of primary cancers, the efficacy of pulmonary metastasectomy (PM) in nonprimary lung cancers has not been investigated. This study aims to investigate the clinical outcomes of PM for non-primary lung cancer.Methods: A systematic search for meta-analyses on PM for nonprimary lung cancers was conducted, encompassing publications up to January 3, 2024. This included seven primary cancers: renal cell, breast, adrenocortical, head and neck cancers, melanoma, germ cell tumors, and sarcoma. Overall survival and recurrence rates post-PM were assessed using random-effect models.Results: This study included 16 systematic-review articles and 101 individual studies, involving 10 277 patients who underwent PM for nonprimary lung cancer. About half of the patients (47.1%) presented with multiple metastasis, and complete resection achieved in 87.2% [95% CI: 83.0-90.8]. The pooled 5-year overall survival rate post-PM was 41.2% [95%CI: 37.1%-45.4%]. Patients with germ cell tumors demonstrated higher survival rate (p < 0.05), while melanoma exhibited the worst outcome (p < 0.05). During follow-up, 57.6% [95% CI: 46.4-68.1] had recurrence; 48% of them had intrathoracic-only recurrence.Conclusion: This study underscores the survival benefits associated with PM. Overall survival rates following PM did not differ based on primary cancer types. These findings highlight the importance of recognizing and incorporating PM into clinical practice when appropriate.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Taxanes and Breast Cancer-Related Lymphedema. 紫杉烷与乳腺癌相关淋巴水肿。

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-15 DOI: 10.1002/jso.28017

Daniel Najafali, Charalampos Siotos, George Kokosis

引用次数: 0

Development and Validation of a Predictive Score for Preoperative Detection of Lymphovascular Invasion in Rectal Cancer. 直肠癌淋巴管侵犯术前检测预测评分的开发与验证

IF 2 3区医学

Journal of Surgical Oncology Pub Date : 2024-12-15 DOI: 10.1002/jso.28043

Sameh H Emile, Nir Horesh, Zoe Garoufalia, Rachel Gefen, Anjelli Wignakumar, Steven D Wexner

{"title":"Development and Validation of a Predictive Score for Preoperative Detection of Lymphovascular Invasion in Rectal Cancer.","authors":"Sameh H Emile, Nir Horesh, Zoe Garoufalia, Rachel Gefen, Anjelli Wignakumar, Steven D Wexner","doi":"10.1002/jso.28043","DOIUrl":"https://doi.org/10.1002/jso.28043","url":null,"abstract":"Background: Lymphovascular invasion (LVI) is an important prognosticator in rectal cancer (RC). We aimed to determine predictors for LVI in RC and incorporate them into a predictive risk score (PRS).Methods: Case-control analysis of predictors of LVI in RC using data from a national database (2010-2019). Main outcome was LVI in RC and its predictors. Odds ratios of significant independent predictors of LVI were incorporated into a PRS.Results: 55,178 patients were included (60.9% male; mean age: 61.3 years). LVI was detected in 10,446 (18.9%). Independent predictors were carcinomas that were signet-ring cell (OR: 1.98, p < 0.001), moderately differentiated (OR: 1.58, p < 0.001), poorly differentiated (OR: 3.9, p < 0.001), or undifferentiated carcinomas (OR: 4.1, p < 0.001), cN1 (OR: 1.21, p < 0.001), and cN2 (OR: 1.49, p < 0.001), stage and incorporated into a PRS (0-8). Incidence of LVI was 16.3% in the low-risk group, 27.8% in the intermediate-risk group, and 40.5% in the high-risk group (p < 0.001). The PPV of the score was 40.5%, NPV was 83.7%, accuracy was 82.4%, and specificity was 97.9%.Conclusions: High-grade adenocarcinomas, signet-ring cell carcinomas, and lymph node involvement in clinical assessment were independently associated with LVI in RC. Incorporation of these predictors into a PRS conferred high specificity and good accuracy.","PeriodicalId":17111,"journal":{"name":"Journal of Surgical Oncology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0