Journal of separation science最新文献

{"title":"Comprehensive Analysis of Corydalis decumbens From Different Regions Using UHPLC-HRMS and Chemometrics","authors":"Jinfeng Zhu,&nbsp;Wenyi Yu,&nbsp;Qing Xu,&nbsp;Hongjiang Liu,&nbsp;Sha Zhang,&nbsp;Yanfang Liu,&nbsp;Aijin Shen,&nbsp;Xinmiao Liang","doi":"10.1002/jssc.70247","DOIUrl":"10.1002/jssc.70247","url":null,"abstract":"<div>\u0000 \u0000 <p>The therapeutic efficacy of traditional Chinese medicines (TCMs) is intrinsically linked to their quality. Differentiating Dao-di medicinal materials from non-Dao-di ones is essential for ensuring the authenticity, superior quality, and therapeutic efficacy of TCMs. <i>Corydalis decumbens</i> (Thunb.) Pers. (<i>C. decumbens</i>) is a renowned traditional Chinese medicinal herb widely employed in clinical practice for treating various diseases, including blood stasis, stroke, hemiplegia, rheumatoid arthritis, and headache. To date, few studies have addressed the geographical origin differentiation of <i>C. decumbens</i>, and the specific chemical constituents responsible for regional variations remain unclear. In this study, a UHPLC-HRMS (ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry) method, in combination with chemometric tools, was developed for the comprehensive profiling of <i>C. decumbens</i> collected from various geographical regions. First, an in-depth characterization of <i>C. decumbens</i> was performed using the established UHPLC-HRMS method. By integrating database matching, fragmentation pathway elucidation, and comparison with authentic standards, a total of 151 compounds were identified, including 131 isoquinoline alkaloids. More specifically, 86 of these compounds were reported in <i>C. decumbens</i> for the first time, including eight isoquinoline alkaloids bearing previously unreported substituent combinations. Based on the identified compounds, principal component analysis (PCA) and orthogonal partial least-squares discriminant analysis (OPLS-DA) were performed to distinguish 33 batches of <i>C. decumbens</i> derived from six geographical origins. The analysis revealed that alkaloids were the primary discriminative constituents contributing to origin differentiation. This work has expanded the chemical foundation of <i>C. decumbens</i> and offers valuable insights into quality control and geographical origin discrimination research.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Analysis of Corydalis decumbens From Different Regions Using UHPLC-HRMS and Chemometrics","authors":"Jinfeng Zhu,&nbsp;Wenyi Yu,&nbsp;Qing Xu,&nbsp;Hongjiang Liu,&nbsp;Sha Zhang,&nbsp;Yanfang Liu,&nbsp;Aijin Shen,&nbsp;Xinmiao Liang","doi":"10.1002/jssc.70247","DOIUrl":"https://doi.org/10.1002/jssc.70247","url":null,"abstract":"<div>\u0000 \u0000 <p>The therapeutic efficacy of traditional Chinese medicines (TCMs) is intrinsically linked to their quality. Differentiating Dao-di medicinal materials from non-Dao-di ones is essential for ensuring the authenticity, superior quality, and therapeutic efficacy of TCMs. <i>Corydalis decumbens</i> (Thunb.) Pers. (<i>C. decumbens</i>) is a renowned traditional Chinese medicinal herb widely employed in clinical practice for treating various diseases, including blood stasis, stroke, hemiplegia, rheumatoid arthritis, and headache. To date, few studies have addressed the geographical origin differentiation of <i>C. decumbens</i>, and the specific chemical constituents responsible for regional variations remain unclear. In this study, a UHPLC-HRMS (ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry) method, in combination with chemometric tools, was developed for the comprehensive profiling of <i>C. decumbens</i> collected from various geographical regions. First, an in-depth characterization of <i>C. decumbens</i> was performed using the established UHPLC-HRMS method. By integrating database matching, fragmentation pathway elucidation, and comparison with authentic standards, a total of 151 compounds were identified, including 131 isoquinoline alkaloids. More specifically, 86 of these compounds were reported in <i>C. decumbens</i> for the first time, including eight isoquinoline alkaloids bearing previously unreported substituent combinations. Based on the identified compounds, principal component analysis (PCA) and orthogonal partial least-squares discriminant analysis (OPLS-DA) were performed to distinguish 33 batches of <i>C. decumbens</i> derived from six geographical origins. The analysis revealed that alkaloids were the primary discriminative constituents contributing to origin differentiation. This work has expanded the chemical foundation of <i>C. decumbens</i> and offers valuable insights into quality control and geographical origin discrimination research.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantification and Aerodynamic Particle Size Distribution of Revefenacin Aerosol With UHPLC-MS/MS","authors":"Difeng Zhu,&nbsp;Jing Dou,&nbsp;Li Ping,&nbsp;Yawen Hong,&nbsp;Chao Chen,&nbsp;Chenxing Yuan,&nbsp;Qixiu Li,&nbsp;Wenjie Luo,&nbsp;Xiaoqing Chi","doi":"10.1002/jssc.70253","DOIUrl":"10.1002/jssc.70253","url":null,"abstract":"<div>\u0000 \u0000 <p>Aerosol inhalation therapy offers significant benefits in treating chronic obstructive pulmonary disease, including rapid onset of action and reduced systemic side effects. Revefenacin, a long-acting bronchodilator, has demonstrated efficacy in improving lung function and alleviating chronic obstructive pulmonary disease symptoms through aerosol delivery. However, quantitative methods for determining the inhaled concentration of revefenacin aerosol remain limited. This study developed and validated a rapid, robust ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method to quantify revefenacin aerosol concentration. The method, with an analysis time of 2 min, exhibited excellent specificity, precision, and a lower limit of quantification of 2 ng/mL. The aerosol extraction recovery averaged 98.5%. The method was successfully applied to assess aerosol concentration and aerodynamic particle size distribution under different sampling conditions. Results showed that after 15 min of nebulization, the average aerosol concentrations collected using syringe aspiration and impactor sampling methods were 0.98 and 0.95 mg/m³, respectively, demonstrating consistency between the techniques. Aerodynamic particle size distribution analysis revealed stable particle size distribution with atomization times of 5 and 15 min, yielding mass median aerodynamic diameters of 2.31 and 2.35 µm, fine particle fractions of 76.5% and 76.7%, and geometric standard deviations of 2.44 and 2.41, respectively. These findings indicate that the aerodynamic properties of revefenacin aerosol remain stable over prolonged nebulization. This study establishes a reliable analytical method for revefenacin aerosol quantification and provides valuable insights into its aerodynamic characteristics, supporting its further application in chronic obstructive pulmonary disease treatment.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Dual Stimulus Response Molecular Imprinted Hydrogel for Specific Recognition and Enrichment of Doxorubicin","authors":"Tian Yawen,&nbsp;Jiang Xinhui,&nbsp;Wang Jie,&nbsp;Cui Jiaping,&nbsp;Fu Xinru,&nbsp;Xia Zhining,&nbsp;Huang Yike","doi":"10.1002/jssc.70249","DOIUrl":"10.1002/jssc.70249","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, dual stimulus-response molecularly imprinted hydrogels (MIHs) with water-soluble doxorubicin (DOX) as the imprinted molecule were developed for improving the selective specific recognition capacity. By using N-isopropylacrylamide (NIPAM) as a temperature-sensitive monomer, and N-[3-(dimethylamino)propyl]methacrylamide (DMAPMA) as a pH-responsive functional monomer, a series of MIHs with different concentration ratios of dual functional monomers and cross-linker were prepared to study the influencing factors of selective recognition. The results show the prepared MIHs have different rigidity and flexibility under different synthesis conditions. The MIH7 with good adsorption performance and specific recognition ability was selected with its molar ratio of NIPAM/DMAPMA/cross-linker (200/10/100). Its imprinting factor of DOX was as high as 2.26. Adsorption kinetic and adsorption thermodynamic studies showed that MIH7 and DOX had high affinity, and its affinity constant <i>K</i>_D was as high as 9.11 × 10⁻⁶ mol/L. For selectivity adsorption, the MIH7 had excellent selectivity at pH 5, with a selectivity factor as high as 1.97 for epirubicin, which is extremely similar in structure, and selectivity factors as high as 6 and 7.68 for idarubicin and oxytetracycline, respectively. The prepared MIH7 was well separated with good specific recognition of DOX in the serum samples, which provided a potential strategy based on the dual stimulus-response and cross-linker for the efficient recognition of water-soluble molecules.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantification and Aerodynamic Particle Size Distribution of Revefenacin Aerosol With UHPLC-MS/MS","authors":"Difeng Zhu,&nbsp;Jing Dou,&nbsp;Li Ping,&nbsp;Yawen Hong,&nbsp;Chao Chen,&nbsp;Chenxing Yuan,&nbsp;Qixiu Li,&nbsp;Wenjie Luo,&nbsp;Xiaoqing Chi","doi":"10.1002/jssc.70253","DOIUrl":"https://doi.org/10.1002/jssc.70253","url":null,"abstract":"<div>\u0000 \u0000 <p>Aerosol inhalation therapy offers significant benefits in treating chronic obstructive pulmonary disease, including rapid onset of action and reduced systemic side effects. Revefenacin, a long-acting bronchodilator, has demonstrated efficacy in improving lung function and alleviating chronic obstructive pulmonary disease symptoms through aerosol delivery. However, quantitative methods for determining the inhaled concentration of revefenacin aerosol remain limited. This study developed and validated a rapid, robust ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method to quantify revefenacin aerosol concentration. The method, with an analysis time of 2 min, exhibited excellent specificity, precision, and a lower limit of quantification of 2 ng/mL. The aerosol extraction recovery averaged 98.5%. The method was successfully applied to assess aerosol concentration and aerodynamic particle size distribution under different sampling conditions. Results showed that after 15 min of nebulization, the average aerosol concentrations collected using syringe aspiration and impactor sampling methods were 0.98 and 0.95 mg/m³, respectively, demonstrating consistency between the techniques. Aerodynamic particle size distribution analysis revealed stable particle size distribution with atomization times of 5 and 15 min, yielding mass median aerodynamic diameters of 2.31 and 2.35 µm, fine particle fractions of 76.5% and 76.7%, and geometric standard deviations of 2.44 and 2.41, respectively. These findings indicate that the aerodynamic properties of revefenacin aerosol remain stable over prolonged nebulization. This study establishes a reliable analytical method for revefenacin aerosol quantification and provides valuable insights into its aerodynamic characteristics, supporting its further application in chronic obstructive pulmonary disease treatment.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Porous Y Zeolite Synthesized With Small Amounts of THF Co-Solvent for Efficient Adsorption of Acetone","authors":"Shuangchun Lu,&nbsp;Xin Yao,&nbsp;Jiabao Liu,&nbsp;Ling Zhao,&nbsp;Haigang Hao","doi":"10.1002/jssc.70251","DOIUrl":"https://doi.org/10.1002/jssc.70251","url":null,"abstract":"<div>\u0000 \u0000 <p>Volatile organic compounds adsorption of zeolite was highly dependent on its structures. Adding organic additives was an effective way to improve the pore structure. However, introducing a large number of additives caused crystallinity reduction and impurity phase generation, which were unfavorable for adsorption. In this work, Y zeolite with high specific surface area and micropore volume was synthesized using bits of tetrahydrofuran (0–1.7 mol% THF) as co-solvent, which attributed to the filling of the co-solvent and the template role of Na⁺ with co-solvent. The highly porous structure and the increase of Na⁺ endowed Y zeolite with superior acetone adsorption performance (0.178 g/g), and it performed better cyclic property after five adsorption–desorption cycles. In addition, the adsorption mechanism was analyzed via adsorption kinetics and density functional theory calculations. The strategy of changing the pore structure and keeping high crystallinity by small amount of THF addition offers evident engineering and economic advantage.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aptamer Affinity Column Extraction Coupled With Immunochromatographic Strip for the Detection of Cadmium(II)","authors":"Peng Li,&nbsp;Jiawei Shi,&nbsp;Cong Ji,&nbsp;Changrui Xing,&nbsp;Yong Fang","doi":"10.1002/jssc.70248","DOIUrl":"https://doi.org/10.1002/jssc.70248","url":null,"abstract":"<div>\u0000 \u0000 <p>The presence of cadmium(II) (Cd(II)) in drinking water is a significant concern. While immunochromatographic strips often lack sensitivity for trace Cd(II) and are easily affected by coexisting ions. In this study, a specific Cd-aptamer affinity column (Cd-AAC) was developed for the extraction of Cd(II). The enriched Cd(II) was eluted using ethylenediaminetetraacetic acid and subsequently quantified rapidly with immunochromatographic strips. The preparation of the Cd-AAC, conditions of solid-phase extraction, the effects of interfering ions, and the reusability of the column were thoroughly investigated. Under optimal conditions, preconcentrating 10 mL of water samples achieved a limit of detection of 0.1 µg/L for Cd(II), with an enhancement factor of 10. The precision of the method (relative standard deviation, <i>n</i> = 6) was 3.1% and 1.6% for intra-batch, and 4.4% and 2.3% for inter-batch measurements of Cd(II) at 0.3 and 1.0 µg/L, respectively. The method was applied to the determination of Cd(II) in water samples, yielding results consistent with inductively coupled plasma mass spectrometry analysis. This approach is straightforward, rapid, economical, and sensitive.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"One Dual Stimulus Response Molecular Imprinted Hydrogel for Specific Recognition and Enrichment of Doxorubicin","authors":"Tian Yawen,&nbsp;Jiang Xinhui,&nbsp;Wang Jie,&nbsp;Cui Jiaping,&nbsp;Fu Xinru,&nbsp;Xia Zhining,&nbsp;Huang Yike","doi":"10.1002/jssc.70249","DOIUrl":"10.1002/jssc.70249","url":null,"abstract":"<div>\u0000 \u0000 <p>In this study, dual stimulus-response molecularly imprinted hydrogels (MIHs) with water-soluble doxorubicin (DOX) as the imprinted molecule were developed for improving the selective specific recognition capacity. By using N-isopropylacrylamide (NIPAM) as a temperature-sensitive monomer, and N-[3-(dimethylamino)propyl]methacrylamide (DMAPMA) as a pH-responsive functional monomer, a series of MIHs with different concentration ratios of dual functional monomers and cross-linker were prepared to study the influencing factors of selective recognition. The results show the prepared MIHs have different rigidity and flexibility under different synthesis conditions. The MIH7 with good adsorption performance and specific recognition ability was selected with its molar ratio of NIPAM/DMAPMA/cross-linker (200/10/100). Its imprinting factor of DOX was as high as 2.26. Adsorption kinetic and adsorption thermodynamic studies showed that MIH7 and DOX had high affinity, and its affinity constant <i>K</i>_D was as high as 9.11 × 10⁻⁶ mol/L. For selectivity adsorption, the MIH7 had excellent selectivity at pH 5, with a selectivity factor as high as 1.97 for epirubicin, which is extremely similar in structure, and selectivity factors as high as 6 and 7.68 for idarubicin and oxytetracycline, respectively. The prepared MIH7 was well separated with good specific recognition of DOX in the serum samples, which provided a potential strategy based on the dual stimulus-response and cross-linker for the efficient recognition of water-soluble molecules.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Porous Y Zeolite Synthesized With Small Amounts of THF Co-Solvent for Efficient Adsorption of Acetone","authors":"Shuangchun Lu,&nbsp;Xin Yao,&nbsp;Jiabao Liu,&nbsp;Ling Zhao,&nbsp;Haigang Hao","doi":"10.1002/jssc.70251","DOIUrl":"10.1002/jssc.70251","url":null,"abstract":"<div>\u0000 \u0000 <p>Volatile organic compounds adsorption of zeolite was highly dependent on its structures. Adding organic additives was an effective way to improve the pore structure. However, introducing a large number of additives caused crystallinity reduction and impurity phase generation, which were unfavorable for adsorption. In this work, Y zeolite with high specific surface area and micropore volume was synthesized using bits of tetrahydrofuran (0–1.7 mol% THF) as co-solvent, which attributed to the filling of the co-solvent and the template role of Na⁺ with co-solvent. The highly porous structure and the increase of Na⁺ endowed Y zeolite with superior acetone adsorption performance (0.178 g/g), and it performed better cyclic property after five adsorption–desorption cycles. In addition, the adsorption mechanism was analyzed via adsorption kinetics and density functional theory calculations. The strategy of changing the pore structure and keeping high crystallinity by small amount of THF addition offers evident engineering and economic advantage.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aptamer Affinity Column Extraction Coupled With Immunochromatographic Strip for the Detection of Cadmium(II)","authors":"Peng Li,&nbsp;Jiawei Shi,&nbsp;Cong Ji,&nbsp;Changrui Xing,&nbsp;Yong Fang","doi":"10.1002/jssc.70248","DOIUrl":"10.1002/jssc.70248","url":null,"abstract":"<div>\u0000 \u0000 <p>The presence of cadmium(II) (Cd(II)) in drinking water is a significant concern. While immunochromatographic strips often lack sensitivity for trace Cd(II) and are easily affected by coexisting ions. In this study, a specific Cd-aptamer affinity column (Cd-AAC) was developed for the extraction of Cd(II). The enriched Cd(II) was eluted using ethylenediaminetetraacetic acid and subsequently quantified rapidly with immunochromatographic strips. The preparation of the Cd-AAC, conditions of solid-phase extraction, the effects of interfering ions, and the reusability of the column were thoroughly investigated. Under optimal conditions, preconcentrating 10 mL of water samples achieved a limit of detection of 0.1 µg/L for Cd(II), with an enhancement factor of 10. The precision of the method (relative standard deviation, <i>n</i> = 6) was 3.1% and 1.6% for intra-batch, and 4.4% and 2.3% for inter-batch measurements of Cd(II) at 0.3 and 1.0 µg/L, respectively. The method was applied to the determination of Cd(II) in water samples, yielding results consistent with inductively coupled plasma mass spectrometry analysis. This approach is straightforward, rapid, economical, and sensitive.</p>\u0000 </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 8","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}