Journal of Research in Clinical Medicine最新文献_第7页

Normative values of Pelli Robson contrast sensitivity test in southeast Iran: A tropical area Pelli Robson对比敏感性试验在伊朗东南部:热带地区的规范性值

Journal of Research in Clinical Medicine Pub Date : 2022-08-16 DOI: 10.34172/jrcm.2022.015

M. Mahjoob, S. Heydarian

{"title":"Normative values of Pelli Robson contrast sensitivity test in southeast Iran: A tropical area","authors":"M. Mahjoob, S. Heydarian","doi":"10.34172/jrcm.2022.015","DOIUrl":"https://doi.org/10.34172/jrcm.2022.015","url":null,"abstract":"Introduction: This study aimed to evaluate the distribution of contrast sensitivity (CS) using Pelli Robson test in normal individuals over seven years old living in Zahedan and examine its relationship with age, gender, and refractive errors. Methods: In this cross-sectional study, simple sampling was performed on the patients aged over seven years and their attendants who had referred to Al-Zahra eye hospital in Zahedan. Complete ophthalmic examinations including vision and refraction assessment, biomicroscopy, and CS evaluation were carried out for all subjects. To evaluate CS, Pelli Robson chart was used at a distance of one meter. The logarithmic CS value of the last triplet in which the patient could accurately read two words was regarded as his/her CS value. Results: Of the 150 patients (300 eyes), 70 (46.66%) were male. The mean age of the subjects was 34.56±16.15 years (ranged from seven to 78 years). The mean and standard deviation of the CS score in two modes of monocular and binocular vision were 1.45±0.19 and 1.57±0.19 log unit, respectively. The mean CS score was not significantly different between men and women (P>0.454), but it decreased significantly with the age (P=0.000). CS was higher in individuals with emmetropia than those with myopia and hypermetropia (P=0.000). There was also a significant correlation between cylinder magnitude and CS (P=0.000). Conclusion: Although Pelli Robson test evaluates CS at low and constant spatial frequencies, its distribution is significantly different among different age groups and even among individuals with different values of refractive errors.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74863485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous retroperitoneal haematoma and rectus sheath haematoma in a COVID-19 patient 1例COVID-19患者并发腹膜后血肿和直肌鞘血肿

Journal of Research in Clinical Medicine Pub Date : 2022-08-03 DOI: 10.34172/jrcm.2022.014

T. Kalaycı

引用次数: 0

Factors associated with disease severity and length of stay in hospitalized COVID-19 patients in Tabriz, Iran: A retrospective cohort study 伊朗大不里士市COVID-19住院患者疾病严重程度和住院时间相关因素:一项回顾性队列研究

Journal of Research in Clinical Medicine Pub Date : 2022-08-01 DOI: 10.34172/jrcm.2022.013

E. Asghari, M. Hosseinzadeh, N. Mahdavi, Vahide Mahmoodi

{"title":"Factors associated with disease severity and length of stay in hospitalized COVID-19 patients in Tabriz, Iran: A retrospective cohort study","authors":"E. Asghari, M. Hosseinzadeh, N. Mahdavi, Vahide Mahmoodi","doi":"10.34172/jrcm.2022.013","DOIUrl":"https://doi.org/10.34172/jrcm.2022.013","url":null,"abstract":"Introduction: The novel coronavirus disease (COVID-19) has spread globally. Early and dynamic detection of prognostic factors is essential to improve the ability to treat COVID-19. The present study aimed to determine clinical characteristics and risk factors associated with the length of hospital stay and disease severity in hospitalized COVID-19 patients in Tabriz, Iran. Methods: This retrospective cohort study included 260 early diagnosed cases with COVID-19 hospitalized at two COVID-19 specialized hospitals in Tabriz, Iran, from April 20 to June 20, 2020. Patients’ medical records were used to collect the data. Severe COVID-19 outcomes included need for intubation, admission to the intensive care unit, or death. The data were analyzed using descriptive and analytical statistics, including chi-squared test, Mann-Whitney U test, and logistic regression analysis in SPSS 16. Results: The need for O2 therapy (adjusted odds ratio [AOR]=4.23; 95% CI: 1.15‒15.51; P=0.03), the increased creatinine levels (AOR=2.71; 95% CI: 1.25‒5.88; P=0.01), and the white blood cell counts (AOR=2.44; 95% CI: 1.12‒5.33; P=0.02) were the main risk factors associated with prolonged hospital stay. Also, having kidney diseases (AOR=7.33; 95% CI=1.94‒27.70; P=0.01), elevated the white blood cell counts (AOR=4.52; 95% CI=1.67‒12.26; P=0.003), and lung diseases (AOR=3.97; 95% CI: 1.18‒13.29; P=0.03) were significant among the predictors of the disease severity. Conclusion: According to the results, hypoxia and underlying diseases might lead to unwanted outcomes. The risk factors identified here confirm previous information and could be helpful to guide early clinical decision-making to reduce the mortality rates and improve the clinical outcomes of COVID-19.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82070755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of two high-risk strains of human papillomavirus (HPV18 and HPV16) with breast cancer in the patients using polymerase chain reaction 用聚合酶链反应研究两种高危人乳头瘤病毒(HPV18和HPV16)与乳腺癌的关系

Journal of Research in Clinical Medicine Pub Date : 2022-08-01 DOI: 10.34172/jrcm.2022.012

Loghman Ghaderi, Majid Montazer, A. Naseri

{"title":"Association of two high-risk strains of human papillomavirus (HPV18 and HPV16) with breast cancer in the patients using polymerase chain reaction","authors":"Loghman Ghaderi, Majid Montazer, A. Naseri","doi":"10.34172/jrcm.2022.012","DOIUrl":"https://doi.org/10.34172/jrcm.2022.012","url":null,"abstract":"Introduction: Two high-risk strains of human papillomavirus (HPV18 and HPV16) immortalize human mammary epithelial cells and reduce their growth factor requirements. Recent studies have identified HPV in a broad range of breast cancer samples. Therefore, the study aimed to assess the association of the mentioned high-risk HPV strains (HPV18, HPV16) with breast cancer in the patients using polymerase chain reaction (PCR) due to the increasing prevalence of breast cancer. Methods: The current work was a retrospective study involving 60 participants (40 patients with breast cancer and 20 healthy people) at Tabriz University of Medical Sciences in 2018-2019. The participants were selected using a convenience sampling method. PCR was used to detect DNA genomes of HPV18 and HPV16. Data was analyzed using Phi and Cramér’s V with SPSS v. 21 by taking into account OR=95% and P=0.05. Results: There was a significant relationship (P value=0.014) between HPV18 and HPV16 infection and breast cancer. Conclusion: A significant relationship was found between the presence of DNA genomes of HPV16 and HPV18 and breast cancer. Therefore, HPV has a significant role in breast cancer.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"84 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88631651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of history of blood pressure and diabetes in the prevalence of stroke in Azar cohort 血压和糖尿病史在阿扎尔队列卒中患病率中的作用

Journal of Research in Clinical Medicine Pub Date : 2022-07-23 DOI: 10.34172/jrcm.2022.011

Salva Hejazi, M. Alizadeh, S. Dastgiri

{"title":"The role of history of blood pressure and diabetes in the prevalence of stroke in Azar cohort","authors":"Salva Hejazi, M. Alizadeh, S. Dastgiri","doi":"10.34172/jrcm.2022.011","DOIUrl":"https://doi.org/10.34172/jrcm.2022.011","url":null,"abstract":"Introduction: The prevalence of diabetes and hypertension has been growing steadily in the last decade. These are important risk factors for stroke and the contribution of each risk factor may change due to geographical location. We conducted the present study with the aim of determining the relationship between blood pressure and diabetes history and stroke in the population covered by the Azar Cohort. Methods: In this case control study which was a subset of Azerbaijan province study (Azar Cohort), 357 patients were divided into patients with and without a history of stroke. The two variables of hypertension and diabetes history, in these two groups were compared. Data were collected and compared with inferential statistical tests. Results: The results showed that blood pressure could increase the risk of stroke by 3.68 times (95% CI: 2.32-5.86). The history of diabetes mellitus in people with and without stroke was not statistically significant (OR=1.54; 95% CI: 0.87-2.72). Conclusion: The results of this study showed that high blood pressure is a predictor of stroke but diabetes cannot be effective in stroke in the cohort population of Azerbaijan.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"665 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76850527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of biochemical and inflammatory markers in assessing COVID-19 severity among the Indian population: An observational study 生化和炎症标志物在评估印度人群COVID-19严重程度中的作用:一项观察性研究

Journal of Research in Clinical Medicine Pub Date : 2022-07-19 DOI: 10.34172/jrcm.2022.010

Reema Kapoor Mehra, Prakriti Gupta, Navpreet Singh

{"title":"Role of biochemical and inflammatory markers in assessing COVID-19 severity among the Indian population: An observational study","authors":"Reema Kapoor Mehra, Prakriti Gupta, Navpreet Singh","doi":"10.34172/jrcm.2022.010","DOIUrl":"https://doi.org/10.34172/jrcm.2022.010","url":null,"abstract":"Introduction: Different laboratory parameters get altered in coronavirus disease 2019 (COVID-19); therefore, the changes of these parameters could help recognize the patients with severe disease. This study was conducted to achieve a comprehensive biochemical and inflammatory profile of COVID-19 among the Indian population. Methods: The study consisted of 730 patients admitted to Jaya Arogya Hospital, Gwalior, with COVID-19 from August 2020 to December 2020. The patients were divided into mild disease group (MDG) (n=533) and severe disease group (SDG) (n=197) depending on certain criteria, and their biochemical and inflammatory markers were collected. Data were analyzed using SPSS version 25. Results: Statistically significant rise in blood urea (P=0.011), serum creatinine (P=0.008), serum bilirubin (P=0.012), interleukin 6 (IL-6) (P<0.001), and troponin I (P<0.001) was observed in SDG as compared to MDG. Serum electrolytes (sodium and potassium) and serum protein (total protein and albumin) showed a significant fall in SDG as compared to MDG (P<0.001 for electrolytes and P=0.023 for proteins). The area under the receiver operating characteristic curve (AUROC) showed a high diagnostic value of IL-6. Conclusion: Patients with severe COVID-19 showed a high prevalence of hyperbilirubinemia, hypoproteinemia, electrolyte imbalance, and raised inflammatory markers (IL-6, troponin I, and procalcitonin). Results showed their effectiveness in assessing disease severity and predicting outcomes in patients with COVID-19.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75198151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical course and outcome of COVID-19 in patients with autoimmune inflammatory diseases under treatment with TNF inhibitors TNF抑制剂治疗下自身免疫性炎症性疾病患者COVID-19的临床病程和结局

Journal of Research in Clinical Medicine Pub Date : 2022-07-04 DOI: 10.34172/jrcm.2022.009

Leila Alizadeh, Maral Bahrami, Kourosh Masnadi Shirazi, M. Ghojazadeh, A. Malek Mahdavi, A. Khabbazi

引用次数: 0

Frequency of borderline personality disorder in suicide patients: A letter to editor 自杀患者中边缘性人格障碍的频率:致编辑的一封信

Journal of Research in Clinical Medicine Pub Date : 2022-06-28 DOI: 10.34172/jrcm.2022.008

Seyyedeh Samin Seyyedfakhri, F. Rahmani

引用次数: 0

The assessment of functional indices of left ventricular wall layers in cases with normal and high blood pressure by layer-specific strain methods 层特异性应变法评价正常和高血压患者左室壁各层功能指标

Journal of Research in Clinical Medicine Pub Date : 2022-05-21 DOI: 10.34172/jrcm.2022.007

Mehrnoosh Toufan Tabrizi, Naser Khezerlu, Venus Shahabi Rabori, Ali Heidari Sarvestani

{"title":"The assessment of functional indices of left ventricular wall layers in cases with normal and high blood pressure by layer-specific strain methods","authors":"Mehrnoosh Toufan Tabrizi, Naser Khezerlu, Venus Shahabi Rabori, Ali Heidari Sarvestani","doi":"10.34172/jrcm.2022.007","DOIUrl":"https://doi.org/10.34172/jrcm.2022.007","url":null,"abstract":"Introduction: The arterial hypertension leading to left ventricular remodeling induces accentuated ventricular wall thickness because of higher afterload. The several surveys about myocardial function in such cases were conducted by imaging studies for the evaluation of myocardial wall thickness without separating the different layers of each other. The aim of this investigation was the evaluation of the functional indices of each layer of the left ventricular myocardium by staining analysis of layers and demonstration of the relationship between ventricular structural remodeling and the functional changes of the ventricle myocardial layers in persons with normal and high blood pressure. Methods: 88 cases (46.6% normotensive and 53.4% hypertensive) were studied by two-dimensional echocardiography and longitudinal and circumferential strain indices. These differentiated variables of heart layers (epicardium, mid myocardium, endocardium) were evaluated. All of them had been analyzed and compared in terms of diastolic dysfunction were compared. Normal diastolic function was defined as: E/A=1 to 2 and deceleration time=150 to 200 ms. Results: Global longitudinal strain (GLS) and global circumferential strain (GCS) strains remarkably declined in epicardial and middle layers of myocardial in hypertensive cases with diastolic dysfunction, although this alternation did not reveal in cases without diastolic dysfunction. Conclusion: The decreasing of GLS and GCS indices of mid-myocardial and epicardial layers have been predicted in cases with high pressure, and the evidences of this situation had been observed in cases with ventricular diastolic dysfunction.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"2016 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86626274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Why INR is outside the therapeutic range in patients with acuteischemic stroke and atrial fibrillation 为什么INR在急性缺血性卒中和房颤患者的治疗范围之外

Journal of Research in Clinical Medicine Pub Date : 2022-04-16 DOI: 10.34172/jrcm.2022.006

Elyar Sadeghi Hokmabadi, S. Shaafi, Yalda Sadeghpour, Reza Deljavan, J. Jalili, M. Ghojazadeh, Elyar Alizade Najmi, S. Charsouei, M. Farhoudi

{"title":"Why INR is outside the therapeutic range in patients with acuteischemic stroke and atrial fibrillation","authors":"Elyar Sadeghi Hokmabadi, S. Shaafi, Yalda Sadeghpour, Reza Deljavan, J. Jalili, M. Ghojazadeh, Elyar Alizade Najmi, S. Charsouei, M. Farhoudi","doi":"10.34172/jrcm.2022.006","DOIUrl":"https://doi.org/10.34172/jrcm.2022.006","url":null,"abstract":"Introduction: Warfarin is still the primary drug used to prevent vascular events in patientswith atrial fibrillation (AF), especially in low-income countries. Therapeutic failure and non-adherenceare common causes of recurrent embolic events. The aim of this study was toinvestigate possible reasons why INR was outside the therapeutic range in patients presentingwith acute ischemic stroke and AF. Methods: This prospective study was performed over a ten-month period and all patientsadmitted with acute ischemic stroke were enrolled. Patients with AF who did not have INRwithin the therapeutic range (INR = 2-3) at the time of admission were identified. During a face-to-face interview, the reasons for INR being outside the therapeutic range were assessed basedon a prepared checklist. Results: During the study period, 810 patients had an acute ischemic stroke, of which 177 hadAF heart rhythm (22%). The median age was 76 (IQR: 71-83), and 87 (52%) were male. Of these177 patients, 44 (25%) had a previous history of AF (\"previous AF\" group) and 133 (75%) werediagnosed with AF during the current hospital admission (\"new AF\" group). Among patients onwarfarin but with INR outside the therapeutic range (29 in all), 20 (69%) did not see a physicianregularly and/or did not take medication according to the physician’s instructions. Conclusion: The most common reason for INR being outside the therapeutic range was patientslack of awareness of their heart disease (unrecognized AF). Other reasons included irregularvisits to the physician and drug non-adherence.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"346 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76916072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0