Journal of Research in Clinical Medicine最新文献

{"title":"Evaluation of the causes and diagnosis of acute hepatitis in children admitted to Tabriz Children Hospital","authors":"B. Abdinia, Maryam Shoaran, Orang Abdollahi, Zahra Golchinfar","doi":"10.34172/jrcm.32218","DOIUrl":"https://doi.org/10.34172/jrcm.32218","url":null,"abstract":"Introduction: The hepatotropic viruses are the most common causes of hepatitis worldwide; however, other infectious and non-infectious reasons can play a role in disease progress. In this study, we examined the infectious and non-infectious causes, and diagnoses of clinical signs of acute hepatitis in children admitted to Tabriz Children Hospital. Methods: In this study, the files of the children hospitalized between 2006 and 2016 with acute viral and non-viral clinical signs were extracted in Tabriz Children Hospital and patients’ information including age, sex, place of residence, type of disease, and their recovery status were investigated. Results: Of all patients, 62 were boys (48.4%) and the mean age of the hospitalized children was 6.92±0.46 years. The most common cause was hepatitis A, followed by autoimmune hepatitis. There was no significant relationship between age, gender, and place of residence with diagnosis, but there was a significant relationship between diagnosis and hepatitis type. Conclusion: The most common type of hepatitis in our study was hepatitis A, and according to its method of transmission, observing health tips is of high significance. Based on the obtained results, autoimmune hepatitis is chronic and requires long-term follow-up.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"44 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140694610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Moving beyond ejection fraction: Exploring comprehensive approaches to assess cardiac function in cardiology","authors":"Mehrnoush Toufan-Tabrizi, Leila Ghahremani-Nasab, Mehran Rahimi","doi":"10.34172/jrcm.34539","DOIUrl":"https://doi.org/10.34172/jrcm.34539","url":null,"abstract":"","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140723305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous intracerebral hemorrhage to reversible cerebral vasoconstriction syndrome: Case report","authors":"T. A. Nazwar, Farhad Bal’afif, D. W. Wardhana, Akhmad Ferro Avisena, Mustofa Mustofa","doi":"10.34172/jrcm.2024.33377","DOIUrl":"https://doi.org/10.34172/jrcm.2024.33377","url":null,"abstract":"Spontaneous intracerebral hemorrhage (sICH) is a common cause of morbidity and mortality in many countries. Hemorrhagic stroke occurs due to the internal hemorrhage inside the brain as a result of blood vessel rupture. Reversible cerebral vasoconstriction syndrome (RCVS) is multifocal arterial constriction and dilation in the cerebral vasculature and can cause subarachnoid hemorrhage and intracerebral hemorrhage (ICH). We present a case of diagnostic studies of sICH to RCVS in a patient with alcohol chronic consumption history.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"125 39","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140078826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tea and coffee consumption impact on the non-alcoholic fatty liver disease: a systematic review and meta-analysis","authors":"S. Dolati, M. Ghojazadeh, Zahra Parsian, Mahsa Kangari, Nafiseh Vahed, Hadi Hamishehkar, H. Soleimanpour","doi":"10.34172/jrcm.2024.33358","DOIUrl":"https://doi.org/10.34172/jrcm.2024.33358","url":null,"abstract":"Introduction: Non-alcoholic fatty liver disease (NAFLD) is diagnosed when≥5–10% of hepatocytes display macroscopic steatosis in the absence of other etiologies of liver disease. Consumption of coffee or tea or both may decrease the risk of NAFLD, as recommended by studies of liver enzymes. Methods: The required data was collected from different databases such as EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL), PubMed, and Web of Science as well as the database inception to July 2021. In addition, pooled mean difference and 95% confidence intervals (CIs) were considered in the random effects model. Results: Of the total collected 218 articles, 8 met our inclusion criteria to be involved in the meta-analysis. Four studies assessed green tea and one study assessed sour tea consumption in NAFLD patients. Three studies assessed coffee use. All studies have shown an inverse correlation of coffee intake with elevated serum enzyme levels. Based on the meta-analysis outcome, the mean alanine aminotransferase (ALT) in the intervention group was measured as 12.50 points less than that of the control group. The mean aspartate aminotransferase (AST) of the intervention group was 9.23 points lower than that of the control group (P value<0.001). Conclusion: There is increasing evidence that steadily revealed an opposite relationship between the consumption amount of green tea and coffee and the risk of liver diseases. This meta-analysis supports the protective role of the mentioned beverages in patients suffering from NAFLD.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140491001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting outcomes in trauma patients by using reverse shock index multiplied by Glasgow coma scores (rSIG): A retrospective cross-sectional study","authors":"S. Paknezhad, Zahra Vand Rajabpour, Hamid Reza Morteza Bagi, Reza Shahryari Ghalehlar, Samira Pourtagi Anvarian","doi":"10.34172/jrcm.2024.33422","DOIUrl":"https://doi.org/10.34172/jrcm.2024.33422","url":null,"abstract":"Introduction: This study aimed to determine the predictive value of the reverse shock index (rSI) using the Glasgow Coma Score (GCS) to predict the outcome of traumatic patients. Methods: This study included all patients with a traumatic injury aged≥18 years with ISS score≥16 and head Abbreviated Injury Scale (AIS)≥2 admitted to the Imam Reza hospital of Tabriz, Iran from 1 March, 2021 to 1 July, 2021. After excluding the patients with incomplete data, 216 patients were enrolled. In this study, the rSIG is the product of rSI multiplied by the GCS score. The patients’ symptoms were recorded routinely in the summary section of all patients’ records using the studied indexes. Data collection was performed using the researcher-made forms. The SPSS software v.21 was used to analyze the data. A P-value<0.05 was considered as statistically significant. Results: The results of data analysis demonstrated that the regression model by two predicting variables of rSI and rSIG was statistically significant. Also, the model can distinguish between the patients who died and those who were discharged. In addition, the Hosmer-Lemeshow test confirmed the model’s advantage and its accuracy (χ2=14.12, df=8, P>0.05). Conclusion: So, the predictive value of rSI with GCS in predicting the outcome of traumatic patients was high.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"43 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140492015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and microbiological characteristics of Chryseobacterium indologenes bacteremia: A case report and review of literature","authors":"Ayushi Jorwal, Pallaavi Goel, V. Garg, Ekadashi Rajni","doi":"10.34172/jrcm.2024.33436","DOIUrl":"https://doi.org/10.34172/jrcm.2024.33436","url":null,"abstract":"Chryseobacterium indologenes is an uncommon human pathogen that is aerobic, non-fermentative, and oxidase and indole positive. Its clinical relevance has yet to be fully determined. An increase in deadly infectious cases has been recorded in recent years, mostly in patients of older age group and immunocompromised states as a result of C. indologenes infection of medical equipment involving fluids and implanted devices. Because C. indologenes is resistant to the majority of antibiotics, therapy is challenging and this bacterium is thought to be an emerging cause of high mortality in critically ill patients. In our study, we describe a case of C. indologenes producing bacteremia in an elderly female patient with a history of ovarian cancer and hepatitis B infection who had underwent a right hemicolectomy with end ileostomy and a distal mucus fistula and was effectively treated with levofloxacin.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"100 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139530404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Donepezil overdose and its atypical clinical presentations: A case report","authors":"Mohammad Delirrad, Habib Ahmadi, Nader Aghakhani","doi":"10.34172/jrcm.2024.32207","DOIUrl":"https://doi.org/10.34172/jrcm.2024.32207","url":null,"abstract":"Donepezil [Aricept®] is a centrally acting reversible acetylcholinesterase inhibitor. We are reporting an unusual case of a 49-year-old male patient with a history of gastric bypass surgery who mistakenly ingested 200 mg of donepezil. During the hospital stay, atypical presentations such as tachycardia, disorientation, mydriasis, and ophthalmic myoclonus were diagnosed. He had experienced convulsions several times and developed rhabdomyolysis. The patient gradually improved under supportive management and was discharged from the hospital after seven days. The authors hope that reporting this case will provide both context for clinicians to be aware of its overdose that may be presented by atypical manifestations or side effects, along with the main muscarinic anticholinergic presentations.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"61 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of luteal phase prolongation with medroxyprogesterone acetate on endometrial thickness and pregnancy rate in women following recurrent implantation failure","authors":"Behnaz Sadeghzadeh Oskouei, Parviz Shahabi, Hossein Babaei, A. Farshbaf-Khalili","doi":"10.34172/jrcm.2024.33310","DOIUrl":"https://doi.org/10.34172/jrcm.2024.33310","url":null,"abstract":"Introduction: Assisted reproductive technology (ART) is increasingly used to help infertile couples to have a child. However, less than one-third of transferred embryos result in successful implantation and live birth. Recurrent implantation failure (RIF) is an outstanding barrier to pregnancy achievement by this advanced technology. This study was conducted to evaluate the hypothesis that luteal phase prolongation would lead to endometrial thickening and decrease the RIF’s rate. Methods: This interventional study was conducted in the infertility clinic of the Alzahra Teaching Hospital and Asadabadi polyclinic, Tabriz, Iran. Sixty women, aged 20–40 years, with a history of RIF following several in vitro fertilization treatment cycles with mid-luteal progesterone levels less than 3 ng/mL, and endometrial thickness less than 8mm were recruited through the purposive sampling method. Participants were treated for six cycles with oral medroxyprogesterone acetate (MPA) tablet 5 mg/12 h initiated from the 16th day of their menstrual cycle for 20 days and evaluated for study outcomes during this course. Endometrial thickness was compared before and after MPA administration in the whole study population. The pregnancy rate was determined. Pregnancy complications and conditions were evaluated during the study. Results: Endometrial thickness was increased in patients after MPA administration (mean difference [95% CI]: 2.66 [2.43 to 2.89]; P<0.001). Overall, 80% (n=48) of participants achieved biochemical pregnancy during a 6-month treatment. Four pregnancies out of 48, were lost in different stages of pregnancy. One participant experienced gestational diabetes in the 24th week of pregnancy. No embryo-fetal abnormality was present until delivery. Conclusion: Administration of MPA following RIF induces endometrial development and facilitates embryo implantation by luteal phase prolongation which results in natural pregnancy achievement followed by timed intercourse.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"118 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139454025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of positive end expiratory pressure during laryngeal mask airway anesthesia on respiratory parameters and abdominal pain in cataract surgery","authors":"Reza Imashi, Ali Akbar Ghamari, Shaghayegh Dadman, Hanieh Sakha, Jafar Rahimipanahi, Amirhossein Fathi","doi":"10.34172/jrcm.2023.33288","DOIUrl":"https://doi.org/10.34172/jrcm.2023.33288","url":null,"abstract":"Introduction: The purpose of this study was to evaluate the effects of positive end expiratory pressure (PEEP) on respiratory parameters and abdominal pain in patients ventilated with a laryngeal mask during cataract surgery. Methods: This clinical trial study included 80 patients in need of cataract surgery (40 in the group without PEEP and 40 in the group with PEEP at 5 cmH2O) who underwent laryngeal mask ventilation during general anesthesia. The parameters of dynamic compliance, pressure peak (Ppeak), tidal volume, SpO2, EtCO2, heart rate, non-invasive blood pressure, and abdominal pain were recorded at intervals of 1, 5, 10, and 20 minutes after the start of anesthesia and were compared between the two groups. Results: Respiratory parameters, heart rate and systolic and diastolic blood pressure were not significantly different between two groups, and only the mean tidal volume at 5, 10, and 20 minutes was significantly higher in the group without PEEP. Conclusion: Application of 5 cmH2O PEEP during ventilation with laryngeal mask in patients undergoing cataract surgery had no significant effect on improving respiratory parameters and pain in the gastric area.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"88 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138606182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of road traffic accidents during the COVID-19 pandemic: A systematic review and meta-analysis","authors":"Kavous Shahsavarinia, H. Salehi-pourmehr, H. Zafardoust, Sepideh Harzand-Jadidi, Robabeh Mehdipour, N. Kabiri","doi":"10.34172/jrcm.2023.33386","DOIUrl":"https://doi.org/10.34172/jrcm.2023.33386","url":null,"abstract":"Introduction: At the beginning of the novel coronavirus disease COVID-19 pandemic, many countries around the world closed their centers and imposed restrictions on urban and interurban traffic. This situation had a significant impact on the occurrence of road traffic accidents. The present systematic review aimed to determine the prevalence of road accidents during the COVID-19 implemented lockdowns. Methods: This systematic review and meta-analysis were conducted based on the Joanna Briggs Institute (JBI) instructions. Two independent reviewers screened articles based on the inclusion criteria for the review and eligible studies for methodological quality using an appropriate appraisal checklist based on the study type. The statistical analysis was performed using the Comprehensive Meta-Analysis (CMA) software. Considering the heterogeneity among studies, a random effect model was adopted to estimate the pooled effect with 95% CI for binary outcomes. Results: The initial search of databases yielded 849 potentially relevant articles, of which, 44 studies were included in this systematic review and of them, 36 were considered for metaanalysis. The random effect model showed an overall prevalence of injury before the lockdown of 24.9% (95% confidence interval: 20.0%-30.5%). Also, the prevalence of injury during the COVID-19 lockdown was 18.8% (95% CI: 14.7%-23.6%). Begg and Mazumdar’s correlation found no publication bias in the meta-analysis. Conclusion: Road traffic injuries, as one of the main causes of death worldwide, took on a new face with the advent of COVID-19. We have found that there is a relatively high prevalence of road traffic accidents before COVID-19 compared to pandemic period.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139214080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}