Journal of Research in Clinical Medicine最新文献

{"title":"Unveiling the neural roadmap: Using fMRI to examine the impacts of positive, negative, and neutral mood induction on driving behavior – A protocol","authors":"Sama Rahnemayan, Homayoun Sadeghi-bazargani, Michael Nitsche, Alireza Lotfi, Morteza Ghojazadeh","doi":"10.34172/jrcm.2023.34518","DOIUrl":"https://doi.org/10.34172/jrcm.2023.34518","url":null,"abstract":"Introduction: The potential association between cognitive functions, mood states, and their effect on driving behavior is complex and has been previously studied in most cases suggesting mood and emotion as possible factors in high-risk driving behaviors. However, their outcome measures are subjective and prone to biases. In this study, we add objective physiological data to explore the physiological and behavioral background of the relevance of mood in high risk driving by functional magnetic resonance imaging (fMRI). Methods: In this study, 28 male right-handed drivers, aged between 20 to 30 years will be randomly selected from records of drivers in the central traffic department and included in the study. Each participant will drive virtually in an fMRI-compatible driving simulator, after positive, negative, and neutral mood induction, and fMRI will be performed to explore driving-related brain activity alterations and the impact of mood state on these effects. All data analyses will be performed using MATLAB (MathWorks, Natick, MA) and the Statistical Parametric Mapping (SPM12) software package. Results: This protocol study introduced a novel protocol to induce positive, negative, and neutral moods and study the impact of mood on driving. Conclusion: Comparing brain activity during driving after positive, negative, and neutral mood induction, this study will help to understand effects of different mood states on driving behavior. Furthermore, comparing the fMRI images of driving under different mood states will clarify the physiological foundation of the impact of mood states on driving behavior. The results of this study will help to introduce physiologically informed preventive or reinforcement strategies to control mood states while driving, and therefore might help to reduce a significant proportion of preventable car accidents.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"11 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135322585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct laboratory parameters as strict prognostic values in the setting of COVID-19 severity","authors":"Farhad Behzadi, Yousef Roosta, Rahim Nejadrahim, Amanj Nabavi","doi":"10.34172/jrcm.2023.33289","DOIUrl":"https://doi.org/10.34172/jrcm.2023.33289","url":null,"abstract":"Introduction: To the best of our knowledge, a new emerging viral infection induced by SARS-CoV-2 was named COVID-19 with high morbidity and mortality on a global scale. To date, COVID-19 is implied as a respiratory disease with varied manifestations from asymptomatic to long-standing complications. In this regard, discerning a potential prognostic value of critical outcomes in the early stages would be more appreciable to stratify the risk of disease severity and 28-day mortality. In this clinical study, we aimed to evaluate distinct laboratory biomarkers, including neutrophil to lymphocyte ratio (NLR), C-reactive protein (CRP), and lactate dehydrogenase (LDH), as reliable indicators to predict disease severity in COVID-19 patients admitted in a medical referral center. Methods: Following the COVID-19 diagnosis, all consecutive patients (n=685) with confirmed SARS-CoV-2 infection were included since September 2020 for one year. Data were collected using electronic medical records. Results: Based on obtained results, NLR and serum level of LDH showed a positive correlation with length of hospital stay. Moreover, the mortality rate and MV required in patients with either positive CRP or the high levels of LDH were remarkably greater than that of the non-severe group (P=0.01). Finally, we could not find significant differences between female and male patients regarding the evaluated parameters. Conclusion: Our findings highlighted those high values of NLR, CRP, and LDH can be considered valuable clinical prognostic aids for risk stratification, identification of disease severity, and triage of patients at the time of admission.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"39 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135461467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of mortality in sepsis with biomarkers and qSOFA score combination: An observational study in a tertiary care centre of western India","authors":"Puneet Rijhwani, Srishti S. Jain, Pallaavi Goel","doi":"10.34172/jrcm.2023.33404","DOIUrl":"https://doi.org/10.34172/jrcm.2023.33404","url":null,"abstract":"Introduction: In any clinical set up, the laboratory biomarkers are very important and can serve in determining the suitable treatment course. In this study, we assumed that considering a combination of biomarkers rather than individual items like lactate, C-reactive protein (CRP) and procalcitonin (PCT) along with qSOFA (quick sequential organ failure assessment) score would be better for predicting 28-day mortality in patients diagnosed with sepsis. Methods: A prospective observational study was conducted in a tertiary care centre in Jaipur, Rajasthan (western India) including 160 participants who were admitted in the intensive care unit (ICU) and diagnosed as sepsis. Detailed history and examination were performed, followed by blood investigations and qSOFA score calculations. Written informed consent was obtained from all participants and institutional ethics committee approval was taken at the beginning of the study. Statistical analysis was done after adequate data collection. Results: Mean CRP [mg/L] was 9±1.41, mean PCT [ng/mL] was 1.6±0.56, mean lactate [mmol/L] was 2.1±1.97 among the study subjects. In this study, specificity (%) of qSOFA+biomarkers (serum lactate, CRP, PCT) was 98.9%, that was more than sensitivity of qSOFA score alone i.e., 40.62%. Although sensitivity (%) of qSOFA was 45.31% that was almost similar to the specificity of qSOFA+biomarkers i.e., 46.8%. Positive predictive value and negative predictive value was also higher in the qSOFA+Biomarker group. Conclusion: The predictive rate of combined method was better than that of qSOFA score alone.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The changing profile of neonatal pathogens and susceptibility pattern: prospective observational study from a tertiary center in South India","authors":"Krishnan Chakkiyar, Gireeshan Veluthedath Kuzhiyil, Maya Sudhakaran, Shameem Anathan Mohammed, Nabeel Valappil Faisal, Mohandas Nair","doi":"10.34172/jrcm.2023.32177","DOIUrl":"https://doi.org/10.34172/jrcm.2023.32177","url":null,"abstract":"Introduction: Changing the pattern of neonatal pathogens poses challenges to the management of neonatal sepsis. Profile and antimicrobial susceptibility of neonatal pathogens were evaluated in this prospective observational study in a tertiary center. Methods: Neonates with risk factors and clinical features of sepsis were screened. Blood culture performed in positive-screen babies. Antimicrobial susceptibility was also evaluated. Statistical significance was tested by the chi-square test and t test accordingly. Univariate analysis was performed to study possible correlations in this regard. Results: Out of 431 suspected cases, 89 neonates (20.65%) had sepsis. The rate of early and late-onset sepsis (LOS) was 48.3% and 51.7%, respectively. The clinical spectrum included septicemia 68 (76.5%), congenital pneumonia 13 (14.7%), meningitis 5 (5.7%), and septic arthritis 3 (3.4%), respectively. Gram-positive bacteria constituted 61 (68.5%), while gram-negative was 28 (31.5%) (P<0.05). Staphylococcus aureus (23.6%) and methicillin-resistant S. aureus (MRSA) (22.5%) were the most common isolates. Acinetobacter (15.8%), coagulase-negative staphylococcus areus (CoNS) (11%), Klebsiella (7.9%), enterococci (8%), E. coli (4.5%), and ß hemolytic streptococci (1 case) were other detected pathogens. MRSA, Acinetobacter, and coagulase-negative S. aureus as a single entity involved in sepsis pathogenesis (50.6%) showed a positive correlation with inborn babies, pre-term, low birth weight, and early-onset sepsis (OR; 95% CI: 2.20; 0.94–5.20, 1.82; 0.79–4.22, 1.25; 0.55–2.89 and 1.05; 0.46–2.50 respectively). Susceptibility pattern was penicillin (12.3%), ampicillin (6.7%), cloxacillin (42.9%), cefotaxime (8%), cefazolin (37.9%), cefoperazone sulbactam (81.5%), piperacillin-tazobactam (68.9%), gentamicin (63.5%), amikacin (47.9%), vancomycin (88.9%), linezolid (88.6%), co-trimoxazole (55.4%), and clindamycin (50%). Conclusion: Gram-positive pathogens and opportunistic pathogens like Acinetobacter predominate over the conventional gram-negative pathogens in neonates. Of note, penicillin, ampicillin, and cefotaxime are not suitable for the empiric treatment of neonatal sepsis.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135131368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alterations of biomarkers in assessing the prognosis of osteoarthritis in patients with total knee replacement: A cross-sectional study","authors":"Keerthy Rethinam Meenakshi Sundaram, Thiagarajan Keddin Alwar, Prakash Ayyadurai, Ganesh Murugan, Mahesh Kumar Kuppusamy, Santhi Silambanan","doi":"10.34172/jrcm.2023.33294","DOIUrl":"https://doi.org/10.34172/jrcm.2023.33294","url":null,"abstract":"Introduction: Osteoarthritis (OA) is a chronic disorder characterized by inflammation, cartilage degeneration and bone remodelling with molecular derangements followed by anatomic and physiologic elements. The aim of the study was to assess the alterations of biomarkers in patients who underwent total knee replacement (TKR) for OA. Methods: A cross-sectional retrospective analysis was carried out on 206 participants who underwent either unilateral or bilateral TKR for knee OA from January 2017 to December 2020. Data regarding medical and surgical history, demographic characteristics, X-ray findings, complete blood count (CBC), plasma glucose and high-sensitive C-reactive protein (hsCRP) were collected and analysed. Ethics approval was obtained. Based on the normality of distribution appropriate statistical tools were used. P value≤0.05 was considered statistically significant. Results: Body mass index was significantly higher in participants who underwent bilateral TKR rather than unilateral TKR. Females were affected at a younger age compared to males. Hypothyroid participants had unilateral than bilateral TKR. Neutrophil lymphocyte ratio was higher in bilateral rather than unilateral TKR (P=0.038). Males had higher monocyte lymphocyte ratio (P≤0.001), especially in individuals 61-80 years of age as well as in obese individuals. Conclusion: The use of markers such as total leukocyte count, differential count, neutrophil to lymphocyte (NLR), monocyte to lymphocyte ratios (MLR) and hsCRP are cost-effective and could predict the severity of the disease. These markers could be used to screen individuals at risk for developing OA of the knee and help in assessing the prognosis; thus allowing surgeons to decide on the appropriate management of the disease.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135722686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of anterior versus posterior circulation cerebral infarctions: Clinical outcomes","authors":"Mazyar Hashemilar, Simin Manouchehri, Mehdi Farhoudi, Sepideh Seyedi-Sahebari","doi":"10.34172/jrcm.2023.32241","DOIUrl":"https://doi.org/10.34172/jrcm.2023.32241","url":null,"abstract":"Introduction: Due to the lack of comprehensive study about the differences between posterior circulation infarction (PCI) and anterior circulation infarction (ACI), this study is performed to determine the clinical consequences of PCI and ACI. Methods: The required information was retrieved from the Tabriz Stroke Registry. Modified Rankin Score (mRS), National Institutes of Health’s Stroke Scale/Score (NIHSS) for severity, and Acute Stroke Treatment (TOAST) classification for types of ischemic stroke as well as the data regarding the risk factors were considered. Results: 701 eligible patients were included in this study, of which 524 (74.75%) were patients with ACI stroke and 177 (25.24%) with PCI stroke. There was no statistically significant difference in terms of age (P=0.724), sex (P=0.559), and pre-stroke mRS (P=0.279). Cardioembolism (CE), undetermined etiology (ESUS), and large arterial stroke (LAA) showed higher incidence in ACI patients, where lacunar type was more prevalent in PCI patients (P=0.01). Hospital NIHSS were significantly different between ACI and PCI groups (P=0.001). Also, regarding the discharged NIHSS patients, there was a significant difference between the groups (P=0.023). Moderate stroke was prominent in both groups in hospitalized (PCI: 57.6% and ACI: 48.9%) and discharged NIHSS patients (PCI: 38.4% and ACI: 42.4%). Conclusion: ACI is about 3-times more prevalent than PCI. There is no relation between the incidence of ACI or PCI and the stroke risk factors. Three months’ mortality did not significantly differ between PCI and ACI.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136010483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between dental amalgam fillings and multiple sclerosis: A systematic review and meta-analysis","authors":"Ali Taghavi Zonouz, F. Pournaghi Azar, Solmaz Pourzare, Hossien Hosinifard, Zahra Molaei","doi":"10.34172/jrcm.2023.31924","DOIUrl":"https://doi.org/10.34172/jrcm.2023.31924","url":null,"abstract":"Introduction: Mercury is a neurotoxic element that is released from dental amalgam restorations. Since circumstantial evidence exists that the pathology of multiple sclerosis (MS) disease might be in part caused or exacerbated by inorganic mercury, we conducted a systematic review and meta-analysis using a comprehensive search strategy. Methods: Data bases (PubMed, Google scholar, Cochrane, Embase, Scopus, Ovid, Proquest, and Web of Science) were searched systematically to find the relationship between dental amalgam and MS. Studies were screened according to a pre-defined protocol. The quality of the articles was evaluated by two individuals. The titles and abstracts of the articles were organized and duplicate articles were discovered with the help of Endnote X5 resource management software. Finally, 6 articles were included in the meta-analysis. Random effect model was chosen to conduct the meta-analysis. Results: Pooled mean difference of restoration numbers between two groups was 0.58 (95% CI: 0.33-0.83, P value<0.001) with greater numbers in MS patients. The pooled OR was 1.02 (95% CI, 0.86-1021, P=0.81), which was slightly higher for those with amalgam so they were more likely to develop MS. This slight increase in risk was not statistically significant. Conclusion: Although those who underwent a large number of amalgam fillings were at higher risk for MS, the difference between the two groups of patients and controls was statistically insignificant. It seems that the number of amalgam fillings can be an influential factor in the possibility of developing MS.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76165859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges of older people experienced after an earthquake disaster situation: A neglected issue","authors":"M. Abbasian, M. Ghojazadeh, E. Sarbazi, Mahla Safaralipour, H. Hamishehkar, H. Soleimanpour","doi":"10.34172/jrcm.2023.33339","DOIUrl":"https://doi.org/10.34172/jrcm.2023.33339","url":null,"abstract":"Introduction: Older adults’ problems and needs may be ignored and not considered a priority matter during disasters due to their complexities and differences from other age groups. This content analysis study was conducted to explain the older adults’ experience of living in tents after the Mianeh county earthquake. Methods: In this research, we used a descriptive qualitative approach. The key elements of Standards for Reporting Qualitative Research (SRQR) were applied to design the research. Data were collected in-depth and semi-structured interviews were done with potential eligible participants. We used heterogeneous purposive sampling (with a maximum variety of 16 older adults with ages in the range of 60–81 years in Mianeh, East Azerbaijan, Iran. The data were analyzed using the conventional content analysis technique. Results: Four main categories emerged, including failure to provide basic physiological needs, poor management of public support, distress and survival attempts, and loss of life authority. The main themes extracted included psychological quality of life and meeting the basic needs (disabilities and inefficiencies). Conclusion: It is beneficial to consider the specific needs of vulnerable groups, such as the elderly population, during the program designing by counties’ crisis management teams.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79370032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumothorax and pulmonary hemorrhage frequency and risk factors of computed tomography-guided transthoracic pulmonary biopsy complications","authors":"Y. Dadalı, Sercan Özkaçmaz, Ümit Çalıkoğlu","doi":"10.34172/jrcm.2023.32199","DOIUrl":"https://doi.org/10.34172/jrcm.2023.32199","url":null,"abstract":"Introduction: We aimed to analyze the frequency and risk factors of pneumothorax and pulmonary hemorrhage caused by Computed Tomography (CT) guided needle biopsy. Methods: Demographical features, pneumothorax and pulmonary hemorrhage frequencies/risk factors, characteristics of lesions of patients who underwent a CT-guided lung biopsy in our institution between January 2013 and August 2013 were reviewed retrospectively. The lesions were classified to the groups as nodular lesions≤3 cm in diameter, nodular lesions>3 cm and consolidated lesions. Pneumothorax and pulmonary hemorrhage frequencies among groups were compared using a chi-square test. A p<0.05 was accepted as statistically significant. Results: A total number of 122 patients with a mean age of 61±13 (19-88) years were included. 28 (23%) patients were female and 94 (77%) were male. 30 (24%) lesions were nodular lesions≤3 cm in diameter, 57 (47%) were nodular lesions>3 cm, and 35 (29%) were consolidated lesions. Pneumothorax developed in 15 (12%) patients while a chest tube insertion was required in 4 (3%) of them. Pulmonary hemorrhage occurred in 14 (11%) patients. Hemoptysis and hemothorax were not observed in this study. Pleura-based lesions was significantly less associated with pneumothorax when compared with ones far from pleura (P<0.001). Usage of 17-gauge needle was significantly more associated with pneumothorax than 19-gauge (p:0.048). Pulmonary hemorrhage was significantly less observed during the biopsy of lesions>3 cm than<3 cm (P<0.001). Conclusion: Nodular lesions≤3 cm, location far from pleura and usage of 17-gauge needle tend to be associated with more frequent lung biopsy complications.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80261370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular responses to laryngoscopy and tracheal intubation with GlideScope or Macintosh laryngoscope in elderly patients undergoing gynecologic surgery: A randomize clinical trial","authors":"Eissa Bilehjani, S. Atashkhoei, B. Naghipour, Foad Loloei, S. Fakhari","doi":"10.34172/jrcm.2023.32208","DOIUrl":"https://doi.org/10.34172/jrcm.2023.32208","url":null,"abstract":"Introduction: The purpose of this study was to compare the GlideScope and Macintosh laryngoscopes for cardiovascular response to laryngoscopy and endotracheal intubation in elderly patients undergoing gynecological procedures. Methods: In this clinical trial, endotracheal intubation was performed using a GlideScope (study group; n=35) and Macintosh laryngoscope (control group; n=35). Hemodynamic parameters were recorded, before induction of anesthesia (baseline), 30 and 15 seconds after starting the laryngoscopy, and every minute up to 5 minutes after intubation. Intubation time and complications of laryngoscopy and intubation were compared between two study groups. Results: Systolic blood pressure (SBP) in 1 (P=0.002), 2 (P=0.003) and 3 (P=0.003) minutes were significantly lower in the study group than that of the control group. The duration of laryngoscopy and intubation was not statistically different between two study groups. The frequency of hypertension after endotracheal intubation in the study group (20%) was significantly lower than that of patients in the control group (45.7%) (P=0.02). There was no significant difference in terms of postoperative complications related to laryngoscopy and intubation (hoarseness and sore throat) between two study groups (P>0.05). Conclusion: This study showed that the use of GlideScope better attenuated cardiovascular responses to laryngoscopy and intubation compared to Macintosh laryngoscope in elderly patients undergoing gynecologic surgery. Also, the frequency of hypertension following laryngoscopy and endotracheal intubation was lower with GlideScope compared to Macintosh laryngoscope. Durations of laryngoscopy, intubation and postoperative complications related to airway management (hoarseness and sore throat) were similar.","PeriodicalId":17071,"journal":{"name":"Journal of Research in Clinical Medicine","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78579148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}