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Jonathan Hutchinson – A multispecialist of medicine 乔纳森-哈钦森 - 医学多面手
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-04-23 DOI: 10.25259/jsstd_4_2024
Vishalakshi S. Pandit
{"title":"Jonathan Hutchinson – A multispecialist of medicine","authors":"Vishalakshi S. Pandit","doi":"10.25259/jsstd_4_2024","DOIUrl":"https://doi.org/10.25259/jsstd_4_2024","url":null,"abstract":"Sir Jonathan Hutchinson was a renowned dermatologist, surgeon, syphilologist, neurologist, and medical educator. Although his fields of interest were medicine, surgery, and ophthalmology, he contributed tremendously in the field of dermatology. He had made many original observations and published articles; many of the signs and diseases are named after him. A few to name are Hutchinson teeth, triad, nail sign, facies. Along with being a prolific author, he was a collector and teacher of many subjects. He had a feather on cap of publishing more than 600 articles and case reports in dermatology. He wrote the 10 volumes of Archives of Surgery, a remarkable singlehanded labor. He had earned honorary degrees from Universities of Glasgow, Cambridge, Edinburgh, Oxford, Dublin, and Leeds. He was knighted in 1908.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"9 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140666394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Asymptomatic skin lesions as a diagnostic clue in multiple myeloma – A case report 作为多发性骨髓瘤诊断线索的无症状皮损--病例报告
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-03-27 DOI: 10.25259/jsstd_3_2024
Anjana Jayaprakash, Thankappan Thonduparampil Pappen, Rhia Sebastian, Balachandran Parapattu Kunjukunju, Anju Joseph, Leny Mathew
{"title":"Asymptomatic skin lesions as a diagnostic clue in multiple myeloma – A case report","authors":"Anjana Jayaprakash, Thankappan Thonduparampil Pappen, Rhia Sebastian, Balachandran Parapattu Kunjukunju, Anju Joseph, Leny Mathew","doi":"10.25259/jsstd_3_2024","DOIUrl":"https://doi.org/10.25259/jsstd_3_2024","url":null,"abstract":"Multiple myeloma (MM) is a rare cancer of plasma cells in the bone marrow. Cutaneous plasmacytoma is an uncommon but specific skin lesion in MM with an incidence of 2%. Cutaneous plasma cell infiltration in pre-existing MM is a very rare phenomenon, with approximately 100 cases described in the literature. Here, we report a case of a 61-year-old male who presented with asymptomatic skin nodules and plaques over the chest, abdomen, and back of the trunk for five months. Histopathological examination showed mononuclear cells with moderate cytoplasm and round to ovoid nuclei. Immunohistochemistry showed CD138 and kappa positivity and lambda and CD20 negativity, confirming the diagnosis of cutaneous plasmacytoma. Bone marrow biopsy and immunohistochemistry revealed bone marrow plasmacytosis with kappa light chain restriction. Serum free light chain ratio was 106.61 and fluorescence in situ hybridization showed del 13q. The clinical features and investigations fulfilled the diagnostic criteria for MM, and the patient was started on chemotherapy, following which the skin lesions improved. Development of skin lesions is seen in the advanced stages of MM and is considered a bad prognostic sign. However, they can also be seen as initial manifestations of the disease, as in this case. Hence, meticulous investigations and early diagnosis are of paramount importance.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"24 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140375291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rituximab-induced vasculitis: A rare occurrence 利妥昔单抗诱发的血管炎：罕见病例
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-03-13 DOI: 10.25259/jsstd_72_2023
Anusha P, Amitta Rachel Santhosh, Amoolya Manalil Trikkovil, Jayalakshmi S, Celine M. I, M. Vineetha, Amitha Mary Jacob
{"title":"Rituximab-induced vasculitis: A rare occurrence","authors":"Anusha P, Amitta Rachel Santhosh, Amoolya Manalil Trikkovil, Jayalakshmi S, Celine M. I, M. Vineetha, Amitha Mary Jacob","doi":"10.25259/jsstd_72_2023","DOIUrl":"https://doi.org/10.25259/jsstd_72_2023","url":null,"abstract":"Rituximab is a chimeric murine/human monoclonal antibody that targets the CD20 antigen expressed on B lymphocytes. It is Food and Drug Administration-approved for use in pemphigus vulgaris (PV). Usual adverse effects are mild, and vasculitis has been reported very rarely. There are only three biopsy-proven case reports of rituximab-induced vasculitis in medical published literature and none in pemphigus. Here, we report a case of rituximab-induced vasculitis in a 46-year-old female with PV.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140247963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eccrine angiomatous hamartoma – A rare painful skin tumor 泌尿生殖器血管瘤--一种罕见的疼痛性皮肤肿瘤
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-03-07 DOI: 10.25259/jsstd_66_2023
Niveditha M, P. Prathap, N. Asokan
{"title":"Eccrine angiomatous hamartoma – A rare painful skin tumor","authors":"Niveditha M, P. Prathap, N. Asokan","doi":"10.25259/jsstd_66_2023","DOIUrl":"https://doi.org/10.25259/jsstd_66_2023","url":null,"abstract":"We report a 68-year-old male with a progressively enlarging, reddish raised painful lesion on the right arm for the previous 3 years. The starch iodine test was positive, dermoscopic findings were yellowish-brown globules on an erythematous background. Biopsy from the lesion showed the presence of eccrine glands, hair follicles, and lobules of capillary sized vessels surrounding hair follicles in the dermis. On immunohistochemistry, epithelial membrane antigen (a marker for eccrine gland) and CD31 (endothelial marker) were positive. A final diagnosis of eccrine angiomatous hamartoma (EAH) was made. There should be a high index of suspicion about EAH if the skin lesions are reddish and tender with associated localized sweating.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"22 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140077380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clinical, dermoscopic, and histopathologic differentiation of cutaneous leishmaniasis from cutaneous sarcoidosis and tuberculosis: A review article 皮肤利什曼病与皮肤肉样瘤病和结核病的临床、皮肤镜和组织病理学鉴别：综述文章
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-02-03 DOI: 10.25259/jsstd_55_2023
Jacob Al-Dabbagh, Nemat Ismail
{"title":"The clinical, dermoscopic, and histopathologic differentiation of cutaneous leishmaniasis from cutaneous sarcoidosis and tuberculosis: A review article","authors":"Jacob Al-Dabbagh, Nemat Ismail","doi":"10.25259/jsstd_55_2023","DOIUrl":"https://doi.org/10.25259/jsstd_55_2023","url":null,"abstract":"Leishmaniasis is a neglected tropical disease caused by infected female sandflies (Phlebotomus and Lutzomyia), which are vector-borne protozoan parasites belonging to the genus Leishmania. The diagnosis of cutaneous leishmaniasis (CL) can be challenging and delayed, particularly in areas where leishmaniasis is not endemic. CL is known as “the great imitator” because it can mimic many skin disorders due to its various clinical manifestations. Cutaneous sarcoidosis (CS) and cutaneous tuberculosis (CTB), which are also known as “the great imitators,” should be differentiated from CL due to the common clinical, dermoscopic, and histopathologic features. In this article, we aim to help clinicians differentiate CL by listing its clinical manifestations those are similar to CS and CTB and highlighting common and uncommon dermoscopic and histopathologic findings. We have also created a brief approach to diagnose CL, CS, and CTB, which is presented as a diagram. A search was performed on PubMed and Google Scholar using the keywords CL, CTB, CS, and granulomatous disease for all articles, with no restrictions. Updated articles on leishmaniasis, tuberculosis, and sarcoidosis, including some new concepts in clinical presentations, dermoscopy, and histopathology, were reviewed.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"22 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139868024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clinical, dermoscopic, and histopathologic differentiation of cutaneous leishmaniasis from cutaneous sarcoidosis and tuberculosis: A review article 皮肤利什曼病与皮肤肉样瘤病和结核病的临床、皮肤镜和组织病理学鉴别：综述文章
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-02-03 DOI: 10.25259/jsstd_55_2023
Jacob Al-Dabbagh, Nemat Ismail
{"title":"The clinical, dermoscopic, and histopathologic differentiation of cutaneous leishmaniasis from cutaneous sarcoidosis and tuberculosis: A review article","authors":"Jacob Al-Dabbagh, Nemat Ismail","doi":"10.25259/jsstd_55_2023","DOIUrl":"https://doi.org/10.25259/jsstd_55_2023","url":null,"abstract":"Leishmaniasis is a neglected tropical disease caused by infected female sandflies (Phlebotomus and Lutzomyia), which are vector-borne protozoan parasites belonging to the genus Leishmania. The diagnosis of cutaneous leishmaniasis (CL) can be challenging and delayed, particularly in areas where leishmaniasis is not endemic. CL is known as “the great imitator” because it can mimic many skin disorders due to its various clinical manifestations. Cutaneous sarcoidosis (CS) and cutaneous tuberculosis (CTB), which are also known as “the great imitators,” should be differentiated from CL due to the common clinical, dermoscopic, and histopathologic features. In this article, we aim to help clinicians differentiate CL by listing its clinical manifestations those are similar to CS and CTB and highlighting common and uncommon dermoscopic and histopathologic findings. We have also created a brief approach to diagnose CL, CS, and CTB, which is presented as a diagram. A search was performed on PubMed and Google Scholar using the keywords CL, CTB, CS, and granulomatous disease for all articles, with no restrictions. Updated articles on leishmaniasis, tuberculosis, and sarcoidosis, including some new concepts in clinical presentations, dermoscopy, and histopathology, were reviewed.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"99 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139808247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermoscopy of lipoid proteinosis – Topographic diverse features 类脂蛋白沉积症的皮肤镜检查--不同的地形特征
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-01-31 DOI: 10.25259/jsstd_69_2023
Arun Somasundaram
{"title":"Dermoscopy of lipoid proteinosis – Topographic diverse features","authors":"Arun Somasundaram","doi":"10.25259/jsstd_69_2023","DOIUrl":"https://doi.org/10.25259/jsstd_69_2023","url":null,"abstract":"","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"305 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140471731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The use of topical Rapamycin in successfully treating non-Langerhans cell histiocytosis in a pediatric patient 使用外用雷帕霉素成功治疗一名儿童患者的非朗格汉斯细胞组织细胞增生症
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-01-20 DOI: 10.25259/jsstd_61_2023
David Pudukadan, Jeevana Mary Jose
{"title":"The use of topical Rapamycin in successfully treating non-Langerhans cell histiocytosis in a pediatric patient","authors":"David Pudukadan, Jeevana Mary Jose","doi":"10.25259/jsstd_61_2023","DOIUrl":"https://doi.org/10.25259/jsstd_61_2023","url":null,"abstract":"Non-Langerhans cell histiocytosis (non-LCH) refers to a collection of medical conditions distinguished by the excessive growth of histiocytes in bodily tissues. It is important to note that these conditions do not meet the established diagnostic criteria for Langerhans cell histiocytosis (LCH). Juvenile xanthogranuloma (JXG) and benign cephalic histiocytosis (BCH) represent the prevailing forms of cutaneous non-LCH. We present a case of JXG which responded to topical treatment with a 0.1% topical ointment of Rapamycin. Rapamycin, an immunosuppressive and antineoplastic agent, can thus be a viable alternative non-invasive topical modality for managing JXG. However, it is imperative to conduct prolonged observations to evaluate the efficacy and potential adverse reactions.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139524674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neutrophilic dermatosis of dorsal hands: A unilateral presentation 手背嗜中性皮肤病：单侧表现
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-01-18 DOI: 10.25259/jsstd_57_2023
Anju Joseph, Thankappan Thonduparampil Pappen, Balachandran Parapattu Kunjukunju, Leny Mathew, Anjana Jayaprakash
{"title":"Neutrophilic dermatosis of dorsal hands: A unilateral presentation","authors":"Anju Joseph, Thankappan Thonduparampil Pappen, Balachandran Parapattu Kunjukunju, Leny Mathew, Anjana Jayaprakash","doi":"10.25259/jsstd_57_2023","DOIUrl":"https://doi.org/10.25259/jsstd_57_2023","url":null,"abstract":"A rare localized version of Sweet syndrome known as neutrophilic dermatosis of dorsal hands is characterized by bluish or hemorrhagic papules, bullae, and nodules on the dorsal hands. Cases have been associated with myeloproliferative disorders, malignancy, inflammatory bowel disease, and rheumatoid arthritis. We are reporting a case of a 39-year-old male presented with sudden onset hyperpigmented raised lesions studded with fluid-filled vesicles on the left dorsal hands. Histology confirmed the clinical diagnosis of neutrophilic dermatosis of dorsal hands. Unilateral presentation of neutrophilic dermatosis of dorsal hands is rarely encountered in day-to-day practice. Hence, we are reporting this case.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"68 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139526972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multifocal infantile hemangiomas in a 4-month-old female infant 一名 4 个月大女婴的多灶性婴儿血管瘤
Journal of Skin and Sexually Transmitted Diseases Pub Date : 2024-01-18 DOI: 10.25259/jsstd_62_2023
Linza P. Zachariah, P. Prathap, N. Asokan, T. Zacharia
{"title":"Multifocal infantile hemangiomas in a 4-month-old female infant","authors":"Linza P. Zachariah, P. Prathap, N. Asokan, T. Zacharia","doi":"10.25259/jsstd_62_2023","DOIUrl":"https://doi.org/10.25259/jsstd_62_2023","url":null,"abstract":"","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"120 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139613573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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