Anusha P, Amitta Rachel Santhosh, Amoolya Manalil Trikkovil, Jayalakshmi S, Celine M. I, M. Vineetha, Amitha Mary Jacob
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引用次数: 0
摘要
利妥昔单抗是一种针对 B 淋巴细胞上表达的 CD20 抗原的嵌合鼠/人单克隆抗体。它已获得美国食品和药物管理局批准，用于治疗寻常天疱疮（PV）。通常的不良反应较轻，血管炎的报道极少。在已发表的医学文献中，仅有三例经活检证实的利妥昔单抗诱发血管炎的病例报告，其中没有一例发生在丘疹性荨麻疹中。在此，我们报告了一例利妥昔单抗诱导的血管炎病例，患者是一名 46 岁的女性丘疹性荨麻疹患者。
Rituximab is a chimeric murine/human monoclonal antibody that targets the CD20 antigen expressed on B lymphocytes. It is Food and Drug Administration-approved for use in pemphigus vulgaris (PV). Usual adverse effects are mild, and vasculitis has been reported very rarely. There are only three biopsy-proven case reports of rituximab-induced vasculitis in medical published literature and none in pemphigus. Here, we report a case of rituximab-induced vasculitis in a 46-year-old female with PV.
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