{"title":"Herpes zoster following ChAdOx1 nCoV-19 corona virus vaccine (recombinant): A case report","authors":"Daniell Henry, David Henry","doi":"10.25259/jsstd_73_2021","DOIUrl":"https://doi.org/10.25259/jsstd_73_2021","url":null,"abstract":"","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74404364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug-induced cutaneous small vessel vasculitis following vortioxetine","authors":"Lakshmi Chembolli","doi":"10.25259/jsstd_69_2021","DOIUrl":"https://doi.org/10.25259/jsstd_69_2021","url":null,"abstract":"","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76130547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunofluorescence in dermatology: A brief review","authors":"Swapna Balakrishnan, Nobin Babu Kalappurayil","doi":"10.25259/jsstd_65_2021","DOIUrl":"https://doi.org/10.25259/jsstd_65_2021","url":null,"abstract":"Immunofluorescence (IF) has been in use for the past five decades, both to investigate the pathophysiology of skin disorders and to help the dermatologists in the diagnosis of various bullous and connective tissue diseases. This review article, deals with different methods, applications, and recent advances in the IF methods used in dermatopathology. Here, we also discuss about the practical aspects of this technique such as handling of skin biopsy specimens and interpretation of direct and indirect IF findings.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72867439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cerebriform congenital melanocytic nevus of scalp and its management using tissue expansion","authors":"Shruti Patel, Naveen Kumar","doi":"10.25259/jsstd_68_2021","DOIUrl":"https://doi.org/10.25259/jsstd_68_2021","url":null,"abstract":"Congenital melanocytic nevi are benign proliferations of cutaneous nevomelanocytes. Usually, they manifest at birth or become apparent within the first few years of life. The nevi show variable surface morphology (papular, rugose, verrucous, or cerebriform). Congenital melanocytic nevus showing cerebriform morphology is a rarity. Early diagnosis and surgical excision are usually recommended in congenital melanocytic nevus to prevent the future risk of malignant transformation which is higher in larger lesions, especially in giant forms (>20 cm in size). An excision of the lesion also helps to avoid the social and psychological consequences arising out of significant cosmetic deformity. We report a 21-year-old patient who presented with a cerebriform congenital melanocytic nevus measuring 10 cm × 7 cm × 2 cm in the right parietal region. Early-onset, pigmented lesion with a cerebriform surface, and the histopathology features of congenital melanocytic nevus were the points that favored the diagnosis of cerebriform congenital melanocytic nevus in our patient. He was treated with excision of the lesion and defect coverage with tissue expansion in two stages. Two rectangular tissue expanders were placed beneath the galea aponeurotica (one with a capacity of 300 cc in the left parietal region and another with 500 cc in the occipital region). Both the expanders were inflated twice to their capacity. Second stage surgery was performed after about 3 months in which the tissue expanders were removed and the pre-expanded scalp skin was used to drape the scalp defect that resulted from the excision of the lesion. An excision and a two staged reconstruction of the scalp using tissue expanders, may ensure a good aesthetic outcome in the management of intermediate to large sized congenital melanocytic nevus.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85834585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nothing is permanent except change……","authors":"K. A. Samad","doi":"10.25259/jsstd_71_2021","DOIUrl":"https://doi.org/10.25259/jsstd_71_2021","url":null,"abstract":"","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83340738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non-teaching institutions – But surely not non-academic","authors":"N. Asokan","doi":"10.25259/jsstd_70_2021","DOIUrl":"https://doi.org/10.25259/jsstd_70_2021","url":null,"abstract":"","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85859541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Results of patch tests (using Indian standard battery of allergens) in cement workers with clinically diagnosed allergic contact dermatitis to cement: A cross-sectional study","authors":"Thacharamban Mansoorali, Abdulsalam Sarin","doi":"10.25259/jsstd_60_2021","DOIUrl":"https://doi.org/10.25259/jsstd_60_2021","url":null,"abstract":"\u0000\u0000The objective of the study was to identify the allergens showing positive patch test reaction (using Indian standard battery of allergens) in cement workers with clinically diagnosed allergic contact dermatitis (CD) to cement attending a tertiary referral center.\u0000\u0000\u0000\u0000We included cement workers with clinically diagnosed allergic CD to cement who attended the dermatology outpatient clinic of our tertiary referral center from January 2013 to December 2013. We did patch testing in all the cases ( after subsidence of active dermatitis) with Indian standard battery of patch test allergens and documented the allergens that showed a positive reaction.\u0000\u0000\u0000\u0000Forty-seven (94%) of the 50 study participants showed a positive reaction to one or more of the allergens. The most common allergen that showed a positive reaction was potassium dichromate (43/50, 86%). Twenty-five patients (50%) showed positive reactions to more than 1 allergen. Four patients (8%) showed positive reactions only to allergens that were not seen in cement.\u0000\u0000\u0000\u0000Small sample size and lack of information on clinical response of dermatitis to avoidance of identified allergen were the major limitations.\u0000\u0000\u0000\u0000Twenty-five (50%) patients showing positive reactions to more than 1 allergen tested and 4 (8%) showing positive patch test reaction to none of the allergens in cement (but to other allergens) highlight the role of patch testing in identifying the probable allergens in patients with clinically diagnosed allergic CD to cement.\u0000","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88481512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Drug interactions of azole antifungals","authors":"N. Sahadevan","doi":"10.25259/jsstd_61_2021","DOIUrl":"https://doi.org/10.25259/jsstd_61_2021","url":null,"abstract":"Drug interactions can occur when two or more medications are simultaneously given, and one drug increases or decreases the effectiveness of the other. Azole antifungal agents show a wide range of interactions with other drugs. Failure to recognize a drug–drug interaction may produce harm to the patient, including enhanced toxicity of the concomitantly administered medication. Most of the interactions of azole antifungals are of pharmacokinetic type. This article reviews the clinically relevant drug interactions of commonly used antifungals - fluconazole and itraconazole.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73995065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Conducting research at non-teaching institutions: Challenges and solutions","authors":"M. Goyal, V. Ravindran","doi":"10.25259/jsstd_64_2021","DOIUrl":"https://doi.org/10.25259/jsstd_64_2021","url":null,"abstract":"Research is the basis of evidence-based medicine, which translates into better health care. While teaching institutions have traditionally been the hub of research activities, it can be carried out in other institutions too. There is no dearth of opportunities and material for research at the non-teaching health-care setups, but often the lack of know-how, workforce, and infrastructure hinder clinicians working in them from taking up research. However, with a systematic approach towards planning and conducting research and by acquiring the requisite knowledge of research methodology, these limitations can be effectively overcome. Not only the knowledge about what kind of research projects can be carried out with the available facilities but also about how to obtain the mandatory ethics committee approval is of paramount importance.","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82141097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amritha Sabitha Kurup, Fairoz Cheriyalingal Parambath, A. Khader, Thazhathekandy Raji, B. Jose
{"title":"Identification and in vitro antifungal susceptibility of dermatophyte species isolated from lesions of cutaneous dermatophytosis: A cross-sectional study","authors":"Amritha Sabitha Kurup, Fairoz Cheriyalingal Parambath, A. Khader, Thazhathekandy Raji, B. Jose","doi":"10.25259/jsstd_64_2020","DOIUrl":"https://doi.org/10.25259/jsstd_64_2020","url":null,"abstract":"\u0000\u0000The objectives of the study were to determine the in vitro susceptibility of dermatophyte species, isolated from the clinically diagnosed lesions of cutaneous dermatophytosis to fluconazole, and terbinafine.\u0000\u0000\u0000\u0000The skin scrapings from clinically diagnosed lesions of cutaneous dermatophytoses were cultured in Sabouraud dextrose agar to identify the causative dermatophyte. Antifungal susceptibility testing was performed using microbroth dilution assay.\u0000\u0000\u0000\u0000During the study period, 94 specimens from clinically diagnosed lesions of cutaneous dermatophytoses were received for fungal culture. Dermatophytes were identified as the causative agent in 44 specimens (Trichophyton rubrum was identified in 18/44 (40.9%), Trichophyton mentagrophytes in 17/44 (38.6%), Trichophyton interdigitale in 5/44 (11.4%), and Nannizia gypsea in 4/44 (9.1%) isolates). Minimum inhibitory concentration (MIC) of fluconazole was ≥64 µg/ml in 22.7% (10/44) and MIC of terbinafine was ≥0.5 µg/ml in 36.4% (16/44) of specimens. When compared to fluconazole, terbinafine showed a lower MIC 50 of 0.0019 µg/ml for Nannizia gypsea.\u0000\u0000\u0000\u0000Small sample size and lack of clinical correlation were the major limitations of the study. Antifungal susceptibility testing limited to fluconazole and terbinafine was another limitation of the study.\u0000\u0000\u0000\u0000Trichophyton rubrum was the most common isolate identified in culture of scrapings from clinically diagnosed lesions of cutaneous dermatophytosis. A rising trend in MIC values of isolates to terbinafine and fluconazole was observed.\u0000","PeriodicalId":17051,"journal":{"name":"Journal of Skin and Sexually Transmitted Diseases","volume":"os-28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87214369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}