皮肤利什曼病与皮肤肉样瘤病和结核病的临床、皮肤镜和组织病理学鉴别:综述文章

Jacob Al-Dabbagh, Nemat Ismail
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引用次数: 0

摘要

利什曼病是一种被忽视的热带疾病,由受感染的雌性沙蝇(Phlebotomus 和 Lutzomyia)引起。皮肤利什曼病(CL)的诊断可能具有挑战性和延迟性,尤其是在利什曼病没有流行的地区。皮肤利什曼病被称为 "伟大的模仿者",因为它的各种临床表现可以模仿许多皮肤疾病。皮肤肉芽肿病(CS)和皮肤结核病(CTB)也被称为 "伟大的模仿者",但由于它们具有共同的临床、皮肤镜和组织病理学特征,因此应将它们与 CL 区分开来。在本文中,我们列举了 CL 与 CS 和 CTB 相似的临床表现,并强调了常见和不常见的皮肤镜和组织病理学结果,旨在帮助临床医生区分 CL。我们还创建了一个诊断 CL、CS 和 CTB 的简要方法,并以图表的形式呈现。我们在 PubMed 和 Google Scholar 上以 CL、CTB、CS 和肉芽肿病为关键词对所有文章进行了搜索,没有任何限制。还查阅了有关利什曼病、结核病和肉芽肿病的最新文章,包括临床表现、皮肤镜检查和组织病理学方面的一些新概念。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The clinical, dermoscopic, and histopathologic differentiation of cutaneous leishmaniasis from cutaneous sarcoidosis and tuberculosis: A review article
Leishmaniasis is a neglected tropical disease caused by infected female sandflies (Phlebotomus and Lutzomyia), which are vector-borne protozoan parasites belonging to the genus Leishmania. The diagnosis of cutaneous leishmaniasis (CL) can be challenging and delayed, particularly in areas where leishmaniasis is not endemic. CL is known as “the great imitator” because it can mimic many skin disorders due to its various clinical manifestations. Cutaneous sarcoidosis (CS) and cutaneous tuberculosis (CTB), which are also known as “the great imitators,” should be differentiated from CL due to the common clinical, dermoscopic, and histopathologic features. In this article, we aim to help clinicians differentiate CL by listing its clinical manifestations those are similar to CS and CTB and highlighting common and uncommon dermoscopic and histopathologic findings. We have also created a brief approach to diagnose CL, CS, and CTB, which is presented as a diagram. A search was performed on PubMed and Google Scholar using the keywords CL, CTB, CS, and granulomatous disease for all articles, with no restrictions. Updated articles on leishmaniasis, tuberculosis, and sarcoidosis, including some new concepts in clinical presentations, dermoscopy, and histopathology, were reviewed.
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