Journal of Saudi Chemical Society最新文献

{"title":"Ultrasound probe-assisted fabrication of 2,3-disubstituted quinazoline-4(3H)-one framework in the existence of SiO2-decorated nano-scale TiO2 composite and investigating their antibacterial attributes via molecular docking simulations","authors":"Mohammad Reza Farhang,&nbsp;Manuchehr Fadaeian,&nbsp;Gholam Reza Najafi,&nbsp;Mahboubeh sadat Sharif","doi":"10.1016/j.jscs.2024.101942","DOIUrl":"10.1016/j.jscs.2024.101942","url":null,"abstract":"<div><div>SiO₂-decorated nano-scale TiO₂ composites have been fabricated via hydrothermal technique (high temperature and pressure) as a robust catalyst. The proposed catalyst was characterized to confirm its structure and composite using characteristics tests. 2,3-disubstituted quinazoline-4(3H)-one framework has been successfully prepared through two paths: reflux and probe ultrasound irradiation (US-probe, 40 W). The efficiency of the two various techniques was comparatively studied on the fundamental properties of the proposed catalyst. According to the obtained results, the US-probe method (due to the cavitation effect) provides favorable reaction conditions (saving energy and time). In this comparative study, SiO₂-decorated nano-scale TiO₂ composites were selected and used as a heterogeneous catalyst in a US-probe-assisted multicomponent reaction of isatoic anhydride, various aryl aldehydes, and amine components (aryl amines, aliphatic amines, and ammonium acetate). In the following, a variety of pharmaceutical 2,3-disubstituted quinazoline-4(3H)-one derivative were prepared under US-probe conditions and obtained excellent yield (90–97 %) within short reaction time (up to 10 min) due to substantial synergic effect between US-probe and SiO₂-decorated nano-scale TiO₂ composites. Besides, chemical/thermal stability, eco-friendliness, and recoverability of the catalyst (7 runs) are other outstanding advantages of this research. Using the drug design approach and computational chemistry, the antibacterial attributes of prepared products were finally perused and checked. All synthesized products have a molecular mass of less than 500 g/mol. Computational chemistry data revealed that prepared products bind well to the agonist at the active site of the P37432 protein (docking score between −5.044 and −3.625), which shows within the inactivation of this protein throughout ailment therapy. According to this, it was found that the prepared products will have the potential to become an antibacterial drug.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101942"},"PeriodicalIF":5.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142554678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced antibacterial testing and latent fingerprint detection using dichlorofluorescein-doped carbon dots","authors":"Aphinya Thinthasit ,&nbsp;Elvaro Islami Muryadi ,&nbsp;Syamsun Jaya ,&nbsp;David Nugroho ,&nbsp;Saksit Chanthai ,&nbsp;Rachadaporn Benchawattananon","doi":"10.1016/j.jscs.2024.101952","DOIUrl":"10.1016/j.jscs.2024.101952","url":null,"abstract":"<div><div>This research presents an innovative multifunctional reagent consisting of dichlorofluorescein-doped carbon dots (CDs-DC) generated from fresh coconut water by a hydrothermal method. This work’s innovation resides in the simultaneous application of CDs-DC for latent fingerprint detection on nonporous surfaces and improved antibacterial efficacy. The incorporation of dichlorofluorescein into the CDs matrix enhances photoluminescent characteristics and improves antibacterial effectiveness against Gram-positive and Gram-negative bacteria (<em>Escherichia coli</em>, <em>Serratia marcescens</em>, <em>Bacillus megaterium</em>, <em>Staphylococcus aureus)</em>. The addition of a starch matrix significantly strengthened this combination, enhancing the adherence and recognition of complex fingerprint patterns under UV light. Furthermore, the CDs-DC demonstrated significant reactive oxygen species (ROS) production, enhancing their antibacterial efficacy. This dual-functional device represents a notable progression in forensic science and antibacterial technology, establishing itself as a sustainable and highly efficient instrument for these purposes.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101952"},"PeriodicalIF":5.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142658840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and assessment of vanadium-based metal–organic frameworks for the effective elimination of hazardous pesticides from aqueous solutions: Mechanism of uptake, adsorption capacities, rate of uptake, and enhancement via the Box-Behnken design","authors":"Abeer Abdulaziz H. Bukhari","doi":"10.1016/j.jscs.2024.101949","DOIUrl":"10.1016/j.jscs.2024.101949","url":null,"abstract":"<div><div>Vanadium metal–organic frameworks (V-MOF) has a great potential to remove contaminants from water that come from agriculture wastewater methyl parathion (MP) pesticides with high effectiveness. Using a variety of methods, such as SEM, FT-IR, XPS), XRD, and BET analysis, the adsorbent was successfully synthesized and characterized. The dimensions of the pores measured at 1.33 nm correspond to the classification of micropores under the IUPAC system. Before the adsorption process, the material had a surface area of 1489.42 m²/g and a pore volume of 0.98 cc/g. After MP adsorption, the surface area, pore size, and pore volume decreased to 1268.42 m²/g, 1.12 nm, and 0.64 cc/g, respectively. Changes in the material’s physical properties indicate that the adsorption process had an effect. 7.2 was the result of controlling the point of zero charge through surface characterization. This information suggests that the surface of the adsorbent has a positive charge at pH below 7.2 and at the pH higher than this value the surface will have a negative charge. It was also looked into how pH affected the adsorption equilibrium. Although fitting to Langmuir isothermally, the kinetics of MP adsorption onto V-MOF are pseudo-second-order fitting. It is very probable that chemisorption was the mode of adsorption because the adsorption energy was 23.62 kJ.mol⁻¹. The enthalpy (ΔH^o) values obtained as a result of studying the thermodynamic parameters are positive, demonstrating that, within this temperature range, the pesticide adsorption process was endothermic., measuring 32.79 kJ.mol⁻¹. Entropy (ΔS^o) readings that are positive indicate that the system’s randomness increased during the adsorption process, reaching 119 J.mol⁻¹K⁻¹, and with rising temperatures, the negative of ΔG^o rise. The effectiveness of the recommended adsorbent was evaluated by filtering wastewater samples in a laboratory environment. It is hypothesized that V-MOF and MP will interact by pore filling, π-π interaction, H-bonding, electrostatic contact, and other possible methods. Considering the specifics of this interaction in great detail is essential to comprehending the nature of adsorption and effectively constructing the adsorbent for use in real-world applications. Water filtering and the treatment of industrial effluents were made simple and effective by the use of V-MOF adsorbent technology. The results indicated that 383.6 mg/g was the maximal adsorption capacity at pH = 6. To evaluate the renewal of the adsorbent, more tests were carried out, and the outcomes showed that the renewal continued even after more than six cycles. The stability of the adsorbent during regeneration was confirmed by using XRD and FT-IR. The Box Behnken design (BBD) was then employed to optimize the adsorption outcomes.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101949"},"PeriodicalIF":5.8,"publicationDate":"2024-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel and reusable magnetic MOF nanocomposite coupled ionic liquid-promoted efficient chemical fixation of CO2 into α-alkylidene cyclic carbonates","authors":"Yu Lin Hu,&nbsp;Yan Hui Lei,&nbsp;Yu Tao Zhang","doi":"10.1016/j.jscs.2024.101950","DOIUrl":"10.1016/j.jscs.2024.101950","url":null,"abstract":"<div><div>Carbon dioxide as a C1 building block to synthesize α-alkylidene cyclic carbonates is an environmental and sustainable approach. In this work, we designed and synthesized a type of multifunctional magnetic MOF nanocomposite catalysts, which could realize the carboxylic cyclization of CO₂ and propargylic alcohols into α-alkylidene cyclic carbonates under solvent-free conditions. Among all the prepared nanocomposites, the MnFe₂O₄@SiO₂@Cu-MOF nanocomposite is the best in catalytic activity combined with the tetrabutylphosphonium acetate ([Bu₄P]OAc) ionic liquid cocatalyst. The catalytic system MnFe₂O₄@SiO₂@Cu-MOF/[Bu₄P]OAc displayed excellent performance in catalyzing the carboxylic cyclization of CO₂ and different propargylic alcohols, and a series of α-alkylidene cyclic carbonates were obtained in high to excellent yields (88 ∼ 98 %) under mild reaction conditions (0.2 MPa, 35 °C). In addition, the two-component catalytic system had high stability and reusability, and can be easily separated and reused up to six consecutive cycles without considerable decrease in catalytic activity. Moreover, using the ionic liquid [Bu₄P]OAc as the cocatalyst, the nanocomposite had good substrate adaptability for the catalytic carboxylic cyclization, which opens interesting prospects for the development of new magnetic MOF nanocomposites as efficient heterogeneous catalysts for the chemical transformation of CO₂ into value-added chemicals.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101950"},"PeriodicalIF":5.8,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous processing of JP-10 production: Hydroisomerization of endo-tetrahydrodicyclopentadiene to exo-tetrahydrodicyclopentadiene using a novel bimetal catalyst of Ba/Se supported on TiO2/SO4","authors":"P. Jayapradha ,&nbsp;P. Tamizhdurai ,&nbsp;C. Kavitha ,&nbsp;V.L. Mangesh ,&nbsp;Ashma Abubakker ,&nbsp;S. Jayakumar ,&nbsp;P. Saravanan ,&nbsp;Krishna Kumar Yadav ,&nbsp;Maha Awjan Alreshidi ,&nbsp;Sultan Alshehery ,&nbsp;Haifa A. Alqhtani ,&nbsp;May Bin-Jumah","doi":"10.1016/j.jscs.2024.101951","DOIUrl":"10.1016/j.jscs.2024.101951","url":null,"abstract":"<div><div>High-energy-density liquid fuels can be utilized as an energetic supplement to conventional fuels and are essential for volume-limited aerospace vehicles to boost payload and flying range. JP-10 has attracted much attention because of its high density, flash point, high volumetric heat, and low freezing point. Here we report the hydroisomerization of <em>endo</em>-tetrahydrodicyclopentadiene to <em>exo</em>-tetrahydrodicyclopentadiene (the main component of JP-10) was investigated over the TiO₂/SO₄ supported Ba(10 %)/Se(5–20 %) catalysts. This work aims to examine changes in continuous processing settings to maximize <em>exo</em>-THDCPD production, selectivity, and conversion. It was discovered that the synthesized TiO₂/SO₄/Ba(10 %)/Se(5–20 %) heterogeneous catalysts were novel, more effective, affordable, environmentally friendly, and simple to produce. The catalyst’s physicochemical characteristics were examined using FT-IR, BET, XRD, HR-SEM, HR-TEM, TGA and NH₃-TPD. The produced TiO₂/SO₄/Ba(10 %)/Se(5–20 %) nano-catalysts have good catalytic activity and a wide range of active Lewis and Brønsted acid sites. Evaluation of the isomerization of <em>endo</em>-THDCPD to <em>exo</em>-THDCPD was conducted in a high-pressure fixed-bed continuous reactor operating at 200 °C, 20 bar of pressure, and 4.0mol/h of H₂ flow rate. According to the investigations, the synthesized catalyst with a 15 % Se load performs exceptionally well, exhibiting 100 % conversion, 98.5 % selectivity, and 98.5 % yield at an H₂ flow rate of 10 ml/min. The isomerized product is used in Jet Propellant-10, a high-density fuel. Under ideal circumstances, <em>exo</em>-THDCPD with a high degree of purity (&gt;98 wt%) was produced without the need for any sort of separation technique.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101951"},"PeriodicalIF":5.8,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced thermal stability photophysical properties of photoselective PMMA/ITO nanohybrid films for greenhouse cooling in hot climates","authors":"Mohammed Alyami ,&nbsp;Samah El-Bashir","doi":"10.1016/j.jscs.2024.101945","DOIUrl":"10.1016/j.jscs.2024.101945","url":null,"abstract":"<div><div>The current research proposed innovative photoselective greenhouse cooling films made from PMMA/ITO nanohybrids, incorporating varying concentrations of Indium tin oxide nanocrystals (ITO NCs) and the fluorescent organic dye Lumogen F Red300, utilizing the solvent casting method. The morphology and structure were examined using transmission electron microscopy (TEM) and X-ray diffraction (XRD), demonstrating good homogeneity and amorphous nature. The impact of different ITO NC concentrations on physical properties was examined through differential scanning calorimetry (DSC), optical absorption, transmission, reflection, fluorescence, and Fourier transform infrared (FT-IR) spectroscopy. Integrating ITO NCs into the PMMA matrix showed enhanced thermal insulation capabilities of PMMA films while maintaining their transparency to photosynthetically active radiation (PAR). Maintaining this balance is crucial because it enables the films to selectively filter and reflect infrared radiation leading to lower greenhouse temperatures while still allowing the essential light needed for plant growth to pass through. This research is particularly significant for Sustainable Development Goals (SDGs) 2 and 13, especially in hot, water-scarce regions, as it protects plants from thermal stress, promotes growth, and supports food security in developing countries.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101945"},"PeriodicalIF":5.8,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142421993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Ni/Co ratio on Ce-Sc-ZrO2 catalysts for selective H2 production via methane partial oxidation","authors":"Norah Alwadai ,&nbsp;Ahmed S. Al-Fatesh ,&nbsp;Kenit Acharya ,&nbsp;Abdulaziz A.M. Abahussain ,&nbsp;Salma A. Al-Zahrani ,&nbsp;Anis H. Fakeeha ,&nbsp;Naif Alarifi ,&nbsp;Khaled M. Banabdwin ,&nbsp;Ahmed A. Ibrahim ,&nbsp;Rawesh Kumar","doi":"10.1016/j.jscs.2024.101948","DOIUrl":"10.1016/j.jscs.2024.101948","url":null,"abstract":"<div><div>Partial oxidation of methane (POM) is a promising route for hydrogen production, and achieving a high H₂ yield with an H₂/CO ratio &gt;3 is highly appealing. Optimization of Ni/Co ratios over Ce-Sc-ZrO₂ (CSZ) is investigated for POM reaction and characterized by X-ray diffraction, Raman spectroscopy, temperature-programmed reduction/oxidation/desorption, and transmission electron microscopy. The active site derived from the reduction of “strongly interacted NiO” is responsible for the dissociation of C–H (of CH₄), resulting high activity towards POM. 5Ni/CSZ has the highest amount of such active sites and attains the highest activity. 5Co/CSZ catalyst has cobalt-based active sites, and there is an inert carbon deposit during the reaction, causing the least activity. 3.75 wt% Ni and 1.25 wt% Co combination over CSZ support surges the highest density of basicity, oxide vacancy, and adequate amount of active sites derived from “strongly interacted NiO”. The active sites with enhanced metal-support interaction are further grown under exposure to oxidizing gas (O₂) and reducing gas (H₂) during the POM reaction. The highest density of basicity and oxide vacancy involves more CO₂ and H₂O in the sequential oxidation of CH₄ under indirect pathways. The exclusive involvement of indirect pathways of POM and inhibition of hydrogen consuming reaction (like reverse water gas shift reaction) over 3.75Ni1.25Co/CSZ results into 48 % H₂ yield and 3.26 H₂/CO ratio up to 24 h time on stream at 600 °C. The H₂ yield doubles to ∼97 %, and the H₂/CO ratio comes close to 2 over 3.75Ni1.25Co/CSZ catalyst at 900 °C.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101948"},"PeriodicalIF":5.8,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating adsorption and removal of divalent Ca2+ and Pb2+ ions from aqueous solutions by gamma-irradiation using quartz tuning fork (QTF) sensor technique","authors":"Reem Alanazi ,&nbsp;Shofiur Rahman ,&nbsp;Mahmoud Al-Gawati ,&nbsp;Khalid E. Alzahrani ,&nbsp;Nahed Alarifi ,&nbsp;Nadyah Alanazi ,&nbsp;Abdullah N. Alodhayb","doi":"10.1016/j.jscs.2024.101947","DOIUrl":"10.1016/j.jscs.2024.101947","url":null,"abstract":"&lt;div&gt;&lt;div&gt;In this study, gold-coated quartz tuning forks (QTFs) sensing devices functionalized with self-assembled monolayers (SAM) of a lower-rim functionalized calix[4]arene methoxy ester were used for the detection of divalent Ca&lt;sup&gt;2+&lt;/sup&gt; and Pb&lt;sup&gt;2+&lt;/sup&gt; ions in aqueous solutions by utilizing adsorption behavior and the radiative effect. The gold-coated QTF functionalized calix[4]arene methoxy ester sensing device was tested by measuring the respective frequency shifts obtained using small (60 µL) samples of aqueous PbCl&lt;sub&gt;2&lt;/sub&gt; at two different concentrations (10&lt;sup&gt;−6&lt;/sup&gt; and 10&lt;sup&gt;−4&lt;/sup&gt; M). For 10&lt;sup&gt;−4&lt;/sup&gt; M solutions of PbCl&lt;sub&gt;2&lt;/sub&gt;, results showed that the resonance frequency shift Δf = 317 Hz, from 32,867 Hz (f&lt;sub&gt;Calix&lt;/sub&gt;) to 32,550 Hz (f&lt;sub&gt;Calix⊃Pb&lt;sup&gt;2+&lt;/sup&gt;&lt;/sub&gt;) due to the absorption of lead (Pb&lt;sup&gt;2+&lt;/sup&gt;) ions (10&lt;sup&gt;-4&lt;/sup&gt; M) by calixl[4]arene methoxy ester receptor molecules on the QTF sensing layer from the aqueous solution to forming the ([Calix ⊃ Pb&lt;sup&gt;2+&lt;/sup&gt;]) complex. The most significant frequency changes were observed at a concentration of 10&lt;sup&gt;−6&lt;/sup&gt; M CaCl&lt;sub&gt;2&lt;/sub&gt;, where CaCl&lt;sub&gt;2&lt;/sub&gt; exhibited the biggest change of 356 Hz, from 32,893 Hz (f&lt;sub&gt;Calix&lt;/sub&gt;) to 32,537 Hz (f&lt;sub&gt;Calix⊃Ca&lt;sup&gt;2+&lt;/sup&gt;&lt;/sub&gt;), compared to 317 Hz for PbCl&lt;sub&gt;2&lt;/sub&gt; (10&lt;sup&gt;−4&lt;/sup&gt; M). The limit of detection was 100 femtomolar (fM) for CaCl&lt;sub&gt;2&lt;/sub&gt; and 245 fM for PbCl&lt;sub&gt;2&lt;/sub&gt;. After that, we irradiated the receptor molecules which was holding Pb&lt;sup&gt;2+&lt;/sup&gt; ions in the complex ([calix ⊃ Pb&lt;sup&gt;2+&lt;/sup&gt;]) on the QTF sensing layer with a radiation dose ranging from 7.5 to 50 µGy of gamma rays from the Cesium-137 source for 30 min. Interestingly, it was observed that the resonance frequency shift (Δf = 54 Hz) back to 32,604 Hz from 32,550 Hz (f&lt;sub&gt;(Calix⊃Pb&lt;sup&gt;2+&lt;/sup&gt;)&lt;/sub&gt;), which strongly suggests that the Pb&lt;sup&gt;2+&lt;/sup&gt; ion removed from ([calix ⊃ Pb&lt;sup&gt;2+&lt;/sup&gt;]) complex on the QTF sensing layer due to gamma radiation dose. To follow up on the radiation effect of the ([calix ⊃ Pb&lt;sup&gt;2+&lt;/sup&gt;]) on the QTF sensing layer, we stopped the gamma radiation source and kept it for an additional 10 min to see if there was any resonance frequency. It was noticed that an additional resonance frequency shifted (Δf = 33 Hz) back to 32,637 Hz from 32,604 Hz after stopping the gamma radiation source for 10 min. We assume that the complex ([calix ⊃ Pb&lt;sup&gt;2+&lt;/sup&gt;]) absorbs the gamma radiation and continues the removal of Pb&lt;sup&gt;2+&lt;/sup&gt; ions from the complex on the sensing layer. A similar phenomenon was also observed for the absorption of lead (Pb&lt;sup&gt;2+&lt;/sup&gt;) ions (10&lt;sup&gt;-6&lt;/sup&gt; M) by calix[4]arene methoxy ester receptor molecules on the QTF sensing layer from the aqueous solution to forming the ([Calix ⊃ Pb&lt;sup&gt;2+&lt;/sup&gt;]) complex. The resonance frequency shift Δf = 142 Hz, from 32,706 Hz (f&lt;sub&gt;Calix&lt;/sub&gt;) to 32,564 Hz (f&lt;sub&gt;Calix⊃Pb&lt;sup&gt;2+&lt;/sup&gt;&lt;/sub&gt;) due to the absorption o","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101947"},"PeriodicalIF":5.8,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facile and controllable hybrid-nanoengineering of MWCNTs/Au@ZIF-8 and AuPt@CeO2 based sandwich electrochemical aptasensor for AFB1 determination in foods and herbs","authors":"Liang Guo ,&nbsp;Shijin Zhou ,&nbsp;Yanju Liu ,&nbsp;Huaixia Yang ,&nbsp;Mingsan Miao ,&nbsp;Wei Gao","doi":"10.1016/j.jscs.2024.101946","DOIUrl":"10.1016/j.jscs.2024.101946","url":null,"abstract":"<div><div>Herein, a sandwich electrochemical sensing strategy for aflatoxin b₁ (AFB₁) detection based on hybrid-nanoengineering was presented. First, Au nanoparticle was doped into zeolitic imidazolate framework-8 (ZIF-8) to form Au@ZIF-8 by in-situ growth method, followed by multi-walled carbon nanotubes (MWCNTs) addition to synthesize MWCNTs/Au@ZIF-8 via self-assembly. The structural “confinement effect” of ZIF-8 afforded a microenvironment for Au nanoparticles and SMCNTs in a certain spatial region, giving MWCNTs/Au@ZIF-8 excellent electrochemical property as the substrate material. In addition, Au-Pt bimetallic nanoparticle, which exhibited excellent stability and catalytic activity was loaded on the hollow cerium oxide (CeO₂) to form AuPt@CeO₂ nanoparticle through one-step aqueous phase reduction. Owning to its high surface-to-volume ratio, satisfied electron transfer efficiency and biocompatibility, massive toluidine blue (TB) and AFB₁ antibody (Ab) could be modified on the AuPt@CeO₂ to form AuPt@CeO₂-Ab-TB, which acted as signal tag for the ultrasensitive assay of AFB₁. The proposed electrochemical sensing system exhibited wide detection range (2 × 10^-5 − 20 ng/mL) and low detection limit (2.13 fg/mL), which has been successfully applied to AFB₁ determination in four real samples. The hybrid nanoengineering presented in this work is an active attempt to prepare high-performance substrate material and signal tag, which provides a new insight for the development of highly sensitive and specific electrochemical sensing systems.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101946"},"PeriodicalIF":5.8,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142358266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discovery of tetrazole thioethers: An efficient, environmentally friendly and metal-free S-arylation using diaryliodonium salts","authors":"Xiaogang Li ,&nbsp;Xuesong Wang ,&nbsp;Yan Wang ,&nbsp;Yinfeng Tan ,&nbsp;Dong Liu ,&nbsp;Xueying Zhang ,&nbsp;Youbin Li ,&nbsp;Junyu Xu","doi":"10.1016/j.jscs.2024.101943","DOIUrl":"10.1016/j.jscs.2024.101943","url":null,"abstract":"<div><div>An efficient, environmentally friendly, and metal-free method for the synthesis of functionalized tetrazole thioethers via the S-arylation of tetrazole-5-thiones using diaryliodonium salts as aryl transfer reagents has been developed. This novel methodology provides rapid access to tetrazole thioether derivatives under facile conditions. Our study underscores the chemoselectivity of unsymmetrical diaryliodonium salts, emphasizing their preference for the transfer of sterically hindered and electron-deficient aryl groups. Notably, the synthesized compound <strong>3h</strong> exhibits antitumor activity against A2780 (ovarian cancer) and MDA-MB-231 (breast cancer) tumor cells. In silico studies predict these compounds to possess good drug-likeness and low toxicity risk. These findings highlight the potential of functionalized tetrazole thioethers as antiproliferative agents and pave the way for further development and optimization in future investigations.</div></div>","PeriodicalId":16974,"journal":{"name":"Journal of Saudi Chemical Society","volume":"28 6","pages":"Article 101943"},"PeriodicalIF":5.8,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}