Manja Krämer, Anastasios Charonis, Samuel Arba-Mosquera
{"title":"Clipped Topography-Guided Treatments: A Different Approach to Custom Corrections.","authors":"Manja Krämer, Anastasios Charonis, Samuel Arba-Mosquera","doi":"10.3928/1081597X-20241002-01","DOIUrl":"https://doi.org/10.3928/1081597X-20241002-01","url":null,"abstract":"<p><strong>Purpose: </strong>To present a new approach to customized treatments that inherently saves tissue by design, especially for pathological corneas.</p><p><strong>Methods: </strong>From the elevation of the anterior cornea and the refractive error of the eye, the target cornea can be calculated and the difference between actual and target cornea corresponds to the tissue to be removed. In this approach, it is further possible to preset the ablation depth at one (Model 1) or two (Models 2 and 3) particular locations. In all three models, the target cornea floats in z-direction, until the depth is reached at one of these defined locations. In Model 2, the depth at the second location is reached by modulating the asphericity, whereas in Model 3, asphericity is maintained but average curvature is modulated to achieve the desired depth at the second location. After floating in z-direction, and modulation, locations with a negative ablation value are set to zero (primary clipping). Additionally, locations exceeding a preset maximum ablation depth are set to a predefined depth (secondary clipping).</p><p><strong>Results: </strong>Simulated cases based on patient diagnosis were used to better explain and illustrate the technique.</p><p><strong>Conclusions: </strong>With this approach, free-form ablation zones are generated, providing for a tissue-saving correction of refractive error and partial correction of higher order aberrations, the overall corneal shape will be recentered, and the corneal curvature gradient is reduced. <b>[<i>J Refract Surg</i>. 2024;40(12):e1003-e1014.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 12","pages":"e1003-e1014"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Microscope-Integrated OCT-Assisted Real-time Monitoring of Central Corneal Thickness During Corneal Cross-linking.","authors":"Nandyala Sushma, Shivam Sharma, Aafreen Bari, Tushar Agarwal, Tanuj Dada, Namrata Sharma","doi":"10.3928/1081597X-20241021-02","DOIUrl":"https://doi.org/10.3928/1081597X-20241021-02","url":null,"abstract":"<p><strong>Purpose: </strong>To assess real-time intraoperative pachymetry changes occurring during corneal cross-linking (CXL) using microscope-integrated optical coherence tomography (Mi-OCT) and compare accuracy of various modalities of pachymetry assessment.</p><p><strong>Methods: </strong>This was a cross-sectional observational comparative study including 45 consecutive patients with progressive keratoconus planned for CXL. Mi-OCT (RESCAN 700) was used to measure central corneal thickness (CCT) during four stages of CXL: before epithelial debridement, after debridement, after riboflavin instillation, and after ultraviolet irradiation. Scheimpflug imaging, anterior segment OCT (AS-OCT), and ultrasound pachymetry were used to assess CCT preoperatively. All data were entered into Excel software (Microsoft Corporation) and analyzed.</p><p><strong>Results: </strong>The CCT significantly decreased after each step of CXL as measured on Mi-OCT (<i>P</i> < .0001). Mi-OCT overestimated the CCT significantly by 1.12 times on average (range: 1.02 to 1.43) compared to ultrasound pachymetry (<i>P</i> = .0004). CCT measured using Scheimpflug imaging and anterior segment OCT was statistically comparable to ultrasound pachymetry.</p><p><strong>Conclusions: </strong>Mi-OCT provides a real-time assessment of CCT during CXL. However, because it overestimates the pachymetry, ultrasound pachymetry remains the gold standard for decision-making during CXL. <b>[<i>J Refract Surg</i>. 2024;40(12):e934-e940.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 12","pages":"e934-e940"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorenzo de Angelis, Vito Romano, Giuseppe Ruben Barbera, Mario Galasso, Jorge L Aliò, Fabrizio Giansanti, Francesco Barca
{"title":"Clinical Comparison of Decentration and Tilt Effects in Iris-Claw and Trans-scleral Plug Lenses: Wavefront Analysis With a Pyramidal Sensor Aberrometer.","authors":"Lorenzo de Angelis, Vito Romano, Giuseppe Ruben Barbera, Mario Galasso, Jorge L Aliò, Fabrizio Giansanti, Francesco Barca","doi":"10.3928/1081597X-20241009-02","DOIUrl":"10.3928/1081597X-20241009-02","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the aberrometric profile of the Artisan Aphakia lens (Opthec BV) and transscleral plug FIL-SSF lens (Soleko) and to assess the impact of tilt and decentration on their optical performance.</p><p><strong>Methods: </strong>This retrospective observational study was conducted at Azienda Ospedaliera Universitaria Careggi, Florence, Italy, with a consecutive cohort of aphakic eyes undergoing secondary lens implantation with an Artisan or FIL-SSF lens. Wavefront analysis was performed using a pyramidal wavefront-based aberrometer (Osiris-T; CSO). Tilt and decentration were calculated using anterior segment optical coherence tomography (MS-39; CSO).</p><p><strong>Results: </strong>The study included 47 eyes from 45 patients: 24 eyes in the FIL-SSF group and 23 eyes in the Artisan group. Decentration was 0.39 ± 0.14 mm in the FIL-SSF group and 0.51 ± 0.16 mm in the Artisan group (<i>P</i> = .02). The mean tilt value was 6.6 ± 2.35 degrees in the FIL-SSF group and 5.9 ± 1.86 degrees in the Artisan group (<i>P</i> = .13). Internal higher order aberrations (HOAs) were 0.23 ± 0.07 μm in the FIL-SSF group and 0.29 ± 0.13 μm in the Artisan group (<i>P</i> = .02). The point spread function (PSF) Strehl ratio was 0.12 ± 0.05 in the FIL-SSF group and 0.10 ± 0.04 (<i>P</i> = .11) in the Artisan group. The PSF Strehl ratio without lower order aberration (PSFw2) was 0.28 ± 0.12 in the FIL-SSF group and 0.23 ± 0.09 in the Artisan group (<i>P</i> = .01).</p><p><strong>Conclusions: </strong>The Artisan and FIL-SSF lenses provide comparable optical performance in terms of the PSF Strehl ratio. However, the Artisan lens appears to be more susceptible to decentration, which may result in increased higher order aberrations and a consequently lower PSFw2 Strehl ratio. <b>[<i>J Refract Surg</i>. 2024;40(12):e926-e933.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 12","pages":"e926-e933"},"PeriodicalIF":2.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yara Bteich, Jad F Assaf, Jeremiah E Gendy, Shady T Awwad
{"title":"Keratorefractive Lenticule Extraction Using the Ziemer FEMTO LDV Z8 Platform (CLEAR): One-Year Results.","authors":"Yara Bteich, Jad F Assaf, Jeremiah E Gendy, Shady T Awwad","doi":"10.3928/1081597X-20241016-01","DOIUrl":"https://doi.org/10.3928/1081597X-20241016-01","url":null,"abstract":"<p><strong>Purpose: </strong>To present the outcomes and detail the surgical procedure employed in the initial 102 eyes treated with keratorefractive lenticule extraction (KLEx) using the FEMTO LDV Z8 platform (Ziemer Ophthalmic Systems).</p><p><strong>Methods: </strong>This was a retrospective analysis of 102 eyes of 53 patients treated with KLEx at the American University of Beirut Medical Center. Visual, refractive, topographic, and aberrometric parameters were evaluated 1 week and 1, 3, 6, and 12 months postoperatively.</p><p><strong>Results: </strong>Mean preoperative spherical equivalent refraction (SEQ) was -4.11 ± 1.82 diopters (D) (range: -10.00 to -1.625 D) and mean preoperative cylinder was -0.75 ± 0.65 D (range: -3.00 to 0.00 D). Postoperatively, the mean SEQ was 0.06 ± 0.54 D (range: -2.88 to +1.00 D) at 1 week and -0.04 ± 0.26 D at 12 months and was within ±0.50 D in 95.6% and ±1.00 D in 100% of eyes. A total of 96.7% of eyes had an uncorrected distance visual acuity (UDVA) of 20/20 at 12 months postoperatively. Fifty percent gained one or more lines of corrected distance visual acuity (CDVA), 5 eyes (5.4%) lost one line, and none lost two or more lines. No suction losses were encountered and all extracted lenticules were intact without tears.</p><p><strong>Conclusions: </strong>The application of KLEx using the FEMTO LDV Z8 platform yields safe and effective outcomes, aligning comparably with established modes of lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis procedures previously employed and accepted within the field of refractive surgery. <b>[<i>J Refract Surg</i>. 2024;40(11):e898-e905.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 11","pages":"e898-e905"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biostatistics and Ophthalmology: The Case of Two Eyes, What Is Correct and What Is Customary.","authors":"Alireza Peyman, Mohsen Pourazizi","doi":"10.3928/1081597X-20240903-03","DOIUrl":"https://doi.org/10.3928/1081597X-20240903-03","url":null,"abstract":"","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 11","pages":"e908"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply: Biostatistics and Ophthalmology: The Case of Two Eyes, What Is Correct and What Is Customary.","authors":"George O Waring","doi":"10.3928/1081597X-20240913-04","DOIUrl":"https://doi.org/10.3928/1081597X-20240913-04","url":null,"abstract":"","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 11","pages":"e908-e909"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laureano A Rementería-Capelo, Inés Contreras, Juan Gros-Otero, Laura Mariñas, Javier Ruiz-Alcocer
{"title":"Visual Quality, Patient Satisfaction, and Photic Phenomena With a Diffractive Intraocular Lens and Its New Evolved Materials Version.","authors":"Laureano A Rementería-Capelo, Inés Contreras, Juan Gros-Otero, Laura Mariñas, Javier Ruiz-Alcocer","doi":"10.3928/1081597X-20240923-02","DOIUrl":"https://doi.org/10.3928/1081597X-20240923-02","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the visual quality, patient satisfaction, and photic phenomena 3 and 12 months after the implantation of two similar diffractive intraocular lenses (IOLs) manufactured with different materials.</p><p><strong>Methods: </strong>This retrospective observational study included patients with the AcrySof PanOptix IOL or the Clareon Pan-Optix IOL (both Alcon Laboratories, Inc). Three and 12 months after the surgery, binocular contrast sensitivity under photopic conditions was measured. The presence of dysphotopsias and difficulties when driving in dim light conditions was also reported. Patient satisfaction was assessed through the Catquest 9-SF questionnaire and patients also reported the need for additional spectacles at different distances. Twelve months after the surgery, the presence of posterior capsule opacification and glistening was reported.</p><p><strong>Results: </strong>The study included 59 patients. Contrast sensitivity was stable in both groups 12 months after the surgery, the proportion of patients that always perceived halos decreased approximately 15%, and difficulties when driving at night were minimized. Both groups showed high and similar rates of satisfaction with their vision and achieved spectacle independence rates greater than 85% at the two visits. The presence of posterior capsule opacification was similar for both groups, whereas 64% and 90% of the eyes were free of glistening in the AcrySof and Clareon groups, respectively.</p><p><strong>Conclusions: </strong>Both diffractive IOLs offer consistent visual outcomes and high rates of patient satisfaction during the initial 12 months after surgery. The results also suggest that the novel material may better preserve the transparency of the IOL in the long term. <b>[<i>J Refract Surg</i>. 2024;40(11):e877-e883.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 11","pages":"e877-e883"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ozgun Melike Gedar Totuk, Mehmet Akif Ozdamar, Meltem Guzin Altınel
{"title":"The Effect of Eyelid Laxity on Corneal Mapping and Corneal Topography.","authors":"Ozgun Melike Gedar Totuk, Mehmet Akif Ozdamar, Meltem Guzin Altınel","doi":"10.3928/1081597X-20240913-01","DOIUrl":"https://doi.org/10.3928/1081597X-20240913-01","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of eyelid laxity on the structure of the cornea.</p><p><strong>Methods: </strong>This was a retrospective study performed in one institution. Patients with and without upper and lower eyelid laxity, which were determined using the snap-back test (SBT) and the upper eyelid distraction test (LDT), were evaluated for corneal structural changes with Scheimpflug imaging corneal tomography for the keratometric readings, and cor-neal spectral domain optical coherence tomography for the epithelial thickness (ET) measurements. The ET values were obtained using the statistics report for the superior quadrant (SET), the inferior quadrant (IET) within the 2- to 7-mm region, and central thickness (CET) within the 2-mm region. The minimum corneal thickness values within the central 5-mm region (MinCT) were also included in the study. Keratometric readings (in diopters), horizontal white-to-white (HWTW) measurements, pachymetry, and ET measurements were assessed along with the presence or absence of eyelid laxity.</p><p><strong>Results: </strong>A total of 170 eyes from 85 patients were evaluated (50.6% with eyelid laxity, and 49.4% without eyelid laxity). There was no significant difference between the mean keratometric readings, HWTW, and the mean IET and CET values (<i>P</i> > .05); however, the difference was significant for the MinCT and SET (<i>P</i> < .05). A statistically significant negative correlation was found between the SET values and age, LDT, and SBT measurements (<i>P</i> < .05).</p><p><strong>Conclusions: </strong>A strong association was found between decreased SET and MinCT values and eyelid laxity. The possible reason for these decreases may be inflammation, which plays a role in the pathophysiology of eyelid laxity. <b>[<i>J Refract Surg</i>. 2024;40(11):e783-e791.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 11","pages":"e783-e791"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reasons for Explantations of Posterior Chamber Phakic Intraocular Lenses in 1,490 Eyes.","authors":"Efekan Coskunseven, Belma Kayhan","doi":"10.3928/1081597X-20240913-03","DOIUrl":"https://doi.org/10.3928/1081597X-20240913-03","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the reasons for the removal and/or exchange of posterior chamber phakic intraocular lenses (PCPIOLs) and the outcomes of these procedures.</p><p><strong>Methods: </strong>In this retrospective study, PCPIOL implantations performed between January 2015 and June 2023 in a single center were reviewed. The study group consisted of the files of eyes with removed and/or exchanged PCPIOL. Visual acuities, refraction errors, endothelial cell counts, and measurements of the vault before and after exchanges were recorded. Reasons for removal and/or exchange were evaluated. The tuck-and-pull technique was used in all explantations.</p><p><strong>Results: </strong>Twenty-three of 1,490 eyes with PCPIOL implantation required removal and/or exchange. Of the explanted eyes, 17 were implanted with PCPIOLs for myopia (1.21% of all myopic corrections) and 6 were implanted with PCPIOLs for hyperopia (6.59% of all hyperopic corrections). The most common reason for removal and/or exchanges after implantation was inappropriate vault (10 of the 23 total removals and/or exchanges), followed by cataract development (7 of the 23 total removals and/or exchanges). A comparison of the biometric characteristics of eyes with PCPIOL removal and/or exchange due to inappropriate vault with other PCPIOL implantations showed that anterior chamber depth, PCPIOL length, and white-to-white distance were significantly higher in the group of explanted eyes (<i>P</i> < .05). All eyes with high vault in myopic patients had a 13.2- or 13.7-mm length PCPIOL.</p><p><strong>Conclusions: </strong>The main reason for PCPIOL removal and/or exchange is vault values outside the ideal limits and cataract development. Before ordering 13.2- and 13.7-mm long PCPIOLs, biometric data of both eyes and recommended PCPIOL sizes should be carefully reviewed. <b>[<i>J Refract Surg</i>. 2024;40(11):e797-e803.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 11","pages":"e797-e803"},"PeriodicalIF":2.9,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142622612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}