Journal of refractive surgery最新文献

{"title":"Quantifying Age-Related Anterior and Posterior Corneal Astigmatism Relationships: Insights for IOL Calculators and Topography-Guided LASIK Protocols.","authors":"Avi Wallerstein, Allison Bernstein, Mark Cohen, Michael Mimouni, Mathieu Gauvin","doi":"10.3928/1081597X-20250417-02","DOIUrl":"https://doi.org/10.3928/1081597X-20250417-02","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the age-related interactions between anterior corneal astigmatism (ACA) and posterior corneal astigmatism (PCA) and their impact on total corneal astigmatism (TCA) using a high-resolution topographer in a large cohort of patients of all ages.</p><p><strong>Methods: </strong>A retrospective review of 19,317 eyes seeking refractive surgery was conducted. ACA, PCA, and TCA were measured using the Pentacam HR (Oculus Optikgeräte GmbH). Corneal data were categorized into astigmatism axes subgroups: with-the-rule (WTR), oblique, and against-the-rule (ATR), and analyzed across 10 age groups. ACA, PCA, and TCA (magnitudes and axes), along with Pearson correlation coefficients between ACA and PCA, were calculated for all groups. Correlations between \"TCA minus ACA\" and selected variables were also assessed.</p><p><strong>Results: </strong>ACA decreased by 37.6% from 18 to 65 years old, followed by a 9.8% increase after 72 years (<i>P</i> < .001). From 18 to 87 years, PCA consistently decreased by 33.3% with age (<i>P</i> < .001). TCA showed a 28% decrease from ages 18 to 59 years, followed by a 32.3% increase after 72 years (<i>P</i> < .001), which we termed a \"V-shaped\" trend. In WTR ACA eyes, the correlation between ACA and PCA decreased from <i>R</i> = 0.78 at 18 years to R ⩽ 0.48 in eyes 65 years or older. Oblique ACA eyes showed lower correlations, peaking at <i>R</i> = 0.51 at 24 years and decreasing to R = 0.02 after 72 years. ATR ACA eyes showed a mild positive correlation in midlife (<i>R</i> = 0.15; 41 years), switching to a moderate inverse correlation in older age (<i>R</i> = -0.3461; ⩾ 72 years). Higher ACA magnitude, WTR ACA axis, and young age showed strong likelihood of overcorrection if ignoring PCA in laser vision correction (LVC), intraocular lens (IOL), or phakic IOL (PIOL) refractive treatment (<i>P</i> < .0001), whereas lower ACA magnitude, ATR ACA axis, and older age were contrarily more likely to undercorrect if ignoring PCA (<i>P</i> < .0001).</p><p><strong>Conclusions: </strong>ACA versus PCA correlations are strongly age-dependent across all orientations. These findings demonstrate that incorporating age-specific correlations into modern IOL calculators could improve TCA prediction accuracy, thereby improving results in refractive IOL surgery. <b>[<i>J Refract Surg</i>. 2025;41(6):e520-e531.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e520-e531"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Impact of Intraocular Higher Order Aberrations on Customized Refractive Surgery in Keratoconus.","authors":"Fengshuang Li, Bing Sun","doi":"10.3928/1081597X-20250417-01","DOIUrl":"https://doi.org/10.3928/1081597X-20250417-01","url":null,"abstract":"","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e622"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refraction Predictability for a Capsulotomy-Fixated Intraocular Lens in Femtosecond Laser-Assisted Cataract Surgery.","authors":"Colya N Englisch, Karl T Boden, André Messias, Peter Szurman, Annekatrin Rickmann, Lisa J Müller, Anna Theresa Lorenz, Berthold Seitz, Achim Langenbucher, Philip Wakili","doi":"10.3928/1081597X-20250417-03","DOIUrl":"https://doi.org/10.3928/1081597X-20250417-03","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the predictability of postoperative refraction for a capsulotomy-fixated intraocular lens (IOL) after femtosecond laser-assisted cataract surgery (FLACS).</p><p><strong>Methods: </strong>Patients with age-related cataracts and no other eye disease who were implanted with the FEMTIS FB-313 IOL (Teleon Surgical BV) during FLACS were included. Using an IOLMaster 700 (Carl Zeiss Meditec), subjective refractive and biometric data were collected preoperatively and at a minimum of 3 months postoperatively. The prediction error (PE), defined as the actual minus predicted refraction, as well as IOL constant optimization and formula performance, were assessed, and the effect of preoperative biometry on the PE was investigated.</p><p><strong>Results: </strong>A total of 70 eyes from 48 patients were included. Hyperopic shifts resulted from applying the Haigis, Holladay 1, SRK/T, and Barrett Universal II formulas, whereas the Hoffer-QST, Pearl-DGS, Cooke K6, EVO, and Kane formulas yielded myopic shifts. The Barrett Universal II formula predicted refraction most accurately, with 48% of eyes within the limits of ±0.25 D. After constant optimization, the formulas displayed significantly lower PEs. Preoperative anterior chamber depth and lens thickness were significantly correlated with the PE. The corresponding positive parameter estimates before and after lens constant optimization were identical.</p><p><strong>Conclusions: </strong>Implantation of the capsulotomy-fixated FEMTIS IOL during FLACS is associated with increased systematic refractive PE, which is directly influenced by preoperative anterior chamber depth and lens thickness. IOL constant optimization enhances prediction accuracy. Relevant inaccuracies also persist in modern formulas, indicating that advancements beyond constant optimization might be crucial to enhance the predictability and accuracy of these calculations in clinical practice. <b>[<i>J Refract Surg</i>. 2025;41(6):e532-e541.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e532-e541"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution of Angle Alpha and Angle Kappa Chord Magnitude and Axes in Myopic and Hyperopic Refractive Surgery Candidates.","authors":"Yara Bteich, Hanadi Ibrahim, Karim Barake, Joseph Khalil, Jad F Assaf, Dan Z Reinstein, Timothy J Archer, Shady T Awwad","doi":"10.3928/1081597X-20250506-04","DOIUrl":"https://doi.org/10.3928/1081597X-20250506-04","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the distribution of angle alpha and angle kappa chord magnitudes, axes, and coordinates in myopic and hyperopic refractive surgery candidates.</p><p><strong>Methods: </strong>A total of 479 eyes were included and divided into myopic and hyperopic groups. Angle alpha and angle kappa chord magnitudes, chord axes, and coordinates were measured for both groups from the Galilei topographer (Ziemer Group) in addition to spherical equivalent refraction (SE) and refractive cylinder. Angle alpha and angle kappa parameters and distribution patterns were compared between groups and correlations with SE and cylinder were analyzed.</p><p><strong>Results: </strong>Angle alpha and angle kappa chord magnitudes were significantly larger in the hyperopic group (alpha: 0.52 ± 0.12 mm; kappa: 0.34 ± 0.12 mm) compared to the myopic group (alpha: 0.38 ± 0.12 mm; kappa: 0.23 ± 0.12 mm). All angle alpha chord axes and the majority of angle kappa chord axes were in the 90° to 180° and 180° to 270° quadrants, with a strong concentration in the 135° to 225° quadrant (angle alpha: 100% for hyperopia and 94% for myopia; angle kappa: 82.7% for hyperopia, 59.4% for myopia). Angle alpha x-component exhibited a positive correlation with hyperopic SE and a negative correlation with myopic SE. There was no correlation between angles alpha and kappa chord magnitudes and cylinder in both groups.</p><p><strong>Conclusions: </strong>Angle alpha chord magnitude is larger and has more consistent axis distribution than that of angle kappa. Chord magnitudes of both angles are larger in hyperopia and have stricter axis distribution compared to myopia. Understanding these relationships is key in planning laser and lens-based refractive procedures. <b>[<i>J Refract Surg</i>. 2025;41(6):e585-e593.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e585-e593"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Lighting, Accommodation, and Pharmacological Conditions on Vault After ICL Implant Refractive Surgery: A Systematic Review.","authors":"Francisco Javier Aguilar-Salazar, Antonio Cano-Ortiz, Timoteo González-Cruces, José-María Sánchez-González","doi":"10.3928/1081597X-20250506-02","DOIUrl":"https://doi.org/10.3928/1081597X-20250506-02","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the influence of lighting conditions, accommodation, and the use of drugs on vault measurement in patients implanted with an Implantable Collamer Lens (ICL; STAAR Surgical). This is the first systematic review to date that analyzes published articles assessing vault variation when measured under different lighting, accommodative, and pharmacological conditions.</p><p><strong>Methods: </strong>A systematic review was conducted, including studies reporting vault measurement under different lighting, accommodative, or pharmacological conditions, in two databases: PubMed and Scopus. The search period was from February 2004 to December 14, 2024. The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and the National Heart, Lung, and Blood Institute's Quality Assessment Tool for Case Series Studies was used to evaluate the quality of the included studies.</p><p><strong>Results: </strong>This systematic review included 22 studies and a total of 1,690 eyes from 1,094 patients. The influence of lighting conditions, accommodation, and drug use was analyzed in 13, 8, and 6 studies, respectively. Vault decreased from 542.12 ± 103.35 to 442.94 ± 102.76 µm (<i>P</i> < .001) when measured under photopic lighting conditions; this reduction was more evident in patients implanted with V4c models compared to V3 and V4 models.</p><p><strong>Conclusions: </strong>The value of the vault is susceptible to changes depending on the conditions under which it is measured. The vault decreases under photopic lighting conditions, as well as during the accommodative state and after administration of miotic and mydriatic drugs. <b>[<i>J Refract Surg</i>. 2025;41(6):e611-e621.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e611-e621"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Pilot Study of Lyophilized Decellularized Storage of SMILE-Derived Lenticules.","authors":"Yiwen Fan, Xiaojun Hu, Xingtao Zhou, Meiyan Li","doi":"10.3928/1081597X-20250417-04","DOIUrl":"https://doi.org/10.3928/1081597X-20250417-04","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the feasibility and biocompatibility of a novel approach for preserving small incision lenticule extraction (SMILE) surgery-derived lenticules by integrating decellularization and lyophilization techniques.</p><p><strong>Methods: </strong>A total of 72 lenticules were divided into two distinct groups: the lyophilized decellularized storage group, which underwent treatment with Triton X-100 and sodium dodecyl sulfate, followed by freeze-drying and storage at -20°C for 24 hours; and the control group, which was stored in a sterile plastic vial at room temperature after extraction. Comprehensive analyses, including scanning electron and transmission electron microscopy, hematoxylin-eosin staining, transmittance measurements, and live/dead staining, were conducted on all lenticules to evaluate their preserved properties. SPSS v20.0 software (SPSS, Inc) was used for statistical analysis of quantitative data, and a <i>P</i> value less than .05 was considered statistically significant.</p><p><strong>Results: </strong>Histomorphology observed that the lyophilized decellularized lenticules effectively removed cellular components while preserving the structural regularity and integrity of the collagen fibers. After rehydration, the lenticules exhibited central thickening and peripheral thinning. The optical transmittance of all rehydrated lyophilized decellularized lenticules was significantly higher than that of lyophilized ones (all <i>P</i> < .05), but still lower than that of fresh lenticules (all <i>P</i> < .05). After 20 to 30 minutes of rehydration, the optical transmittance of the lenticules exceeded 80%, and both weight and optical transmittance stabilized (all <i>P</i> > .05). Furthermore, in vitro biocompatibility testing revealed relatively good morphology and comparable quantity of human keratocytes, with no detection of dead cells.</p><p><strong>Conclusions: </strong>Lyophilized decellularized storage of SMILE-derived lenticules effectively preserved the tissue morphology, optical transparency, and biocompatibility, suggesting potential for clinical application. <b>[<i>J Refract Surg</i>. 2025;41(6):e542-e550.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e542-e550"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: Exploring the Impact of Intraocular Higher Order Aberrations on Customized Refractive Surgery in Keratoconus.","authors":"Karim Kozhaya, Carl-Joe Mehanna, Lara Asroui, Romy Bejjani, Samuel Arba-Mosquera, Hazem M Mousa, Saleh Bahir Al-Ulloom, Shady T Awwad","doi":"10.3928/1081597X-20250512-01","DOIUrl":"https://doi.org/10.3928/1081597X-20250512-01","url":null,"abstract":"","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e622-e623"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative OCT Enables Prediction of 3-Month Postoperative Lens Separation Vault for the Implantable Collamer Lens.","authors":"Maxwell J B Reinstein, Dan Z Reinstein, Timothy J Archer, Ruchi Gupta, Joseph G Potter","doi":"10.3928/1081597X-20250417-06","DOIUrl":"https://doi.org/10.3928/1081597X-20250417-06","url":null,"abstract":"<p><strong>Purpose: </strong>To develop and test a multivariate model using intraoperative optical coherence tomography (iOCT) (ARTEVO 800; Carl Zeiss Meditec) to predict the 3-month lens separation vault of the Implantable Collamer Lens (ICL; STAAR Surgical).</p><p><strong>Methods: </strong>A retrospective analysis of consecutive V4c EVO and EVO+ ICL procedures was conducted at London Vision Clinic, London, United Kingdom. ICL size was preoperatively chosen using Insight 100 VHF digital ultrasound (ArcScan, Inc) and the Reinstein ICL Sizing Formula V2. Central vault was recorded intraoperatively by iOCT. AS-OCT (MS-39; CSO Italia) measured vault at 30 minutes, 1 and 4 days, and 1 and 3 months after surgery. Stepwise multiple linear regression analysis evaluated the correlation between preoperative and iOCT-derived vault measurements with the 3-month vault. A predictive formula was derived and tested on 40 consecutive cases to estimate the accuracy and repeatability of vault prediction.</p><p><strong>Results: </strong>A total of 153 eyes were included in the training set. Mean central vault was 829 ± 330 µm intraoperatively and 594 ± 218 µm at 3 months. Regression analysis indicated that intraoperative vault, ciliary body inner diameter, crystalline lens rise from the sulcus plane, and lens size were significant factors (all <i>P</i> < .001) in predicting the change between intra-operative and 3-month vault. The derived formula predicted the 3-month vault within 100 µm of the achieved vault for 58% of eyes in the test set, within 200 µm for 83%, within 300 µm for 93%, and within 350 µm for 100%.</p><p><strong>Conclusions: </strong>iOCT is a valuable tool for intraoperative determination of lens size suitability, increasing patient safety, and potentially avoiding secondary procedures. <b>[<i>J Refract Surg</i>. 2025;41(6):e575-e584.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e575-e584"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"KERATO Biomechanics Study 2: A Comparative Evaluation Before and After Corneal Cross-Linking Using Brillouin Microscopy and Dynamic Scheimpflug Imaging.","authors":"Riccardo Vinciguerra, Robert Herber, Kaman Zeng Cen, Mario R Romano, Frederik Raiskup, Ramin Khoramnia, Paolo Vinciguerra","doi":"10.3928/1081597X-20250506-01","DOIUrl":"https://doi.org/10.3928/1081597X-20250506-01","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate biomechanical changes induced by epithelium-off corneal cross-linking (CXL) in progressive keratoconus using Brillouin microscopy (BOSS; Intelon Optics) and ultra-high-speed Scheimpflug camera (Corvis ST; Oculus Optikgeräte GmbH).</p><p><strong>Methods: </strong>Twenty-three eyes from 24 patients were included in this retrospective, multicenter study. Biomechanical properties were assessed before and 1 month after CXL using the BOSS and Corvis ST. Brillouin measurements included mean, minimum, and maximum Brillouin frequency shift (BFS) and sectors (inferior, equator, and superior). The Corvis ST assessed dynamic corneal response (DCR) parameters, including inverse concave radius (1/R) and stress-strain index (SSI). Statistical analyses included Wilcoxon tests, Pearson correlation, and linear mixed models, with adjustments for corneal pachymetry.</p><p><strong>Results: </strong>Brillouin microscopy demonstrated significant stiffening after CXL, with increases in mean BFS and maximum BFS, together with inferior and equatorial regions (<i>P</i> < .001). A strong correlation was observed between preoperative BFS and postoperative changes (<i>R</i>² = 0.597, <i>P</i> < .001). The Corvis ST confirmed biomechanical stiffening with a significant decrease in 1/R values (<i>P</i> = .002), although no significant changes were observed in SSI.</p><p><strong>Conclusions: </strong>Both Brillouin microscopy and the Corvis ST effectively detected corneal stiffening after CXL, with Brillouin technology offering localized biomechanical insights. These findings highlight the potential of Brillouin microscopy for guiding customized CXL treatments and underscore its complementary role alongside the Corvis ST. <b>[<i>J Refract Surg</i>. 2025;41(6):e594-e601.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e594-e601"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Short-term Crystalline Lens Positional Shifts Following ICL Implantation Using SS-OCT Integrated With Multi-task Deep Learning.","authors":"Zhengwei Zhang, Kaiwen Li, Zhao Wang, Jinhan Yao, Shuimiao Chang, Jiewei Liu, Xiaogang Wang","doi":"10.3928/1081597X-20250506-06","DOIUrl":"https://doi.org/10.3928/1081597X-20250506-06","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the tilt and decentration of the crystalline lens shortly after Implantable Collamer Lens (ICL) implantation.</p><p><strong>Methods: </strong>All enrolled patients underwent anterior segment swept-source optical coherence tomography (SS-OCT) both before and within 1 week after ICL surgery. A multitask network automatically conducted SS-OCT image segmentation and provided quantitative assessments of the crystalline lens's tilt and decentration. For data following a normal distribution, paired <i>t</i>-tests were performed, whereas for data not meeting normality assumptions, the Wilcoxon signed-rank test was used.</p><p><strong>Results: </strong>The final data analysis included 42 eyes from 26 patients. No statistically significant difference was observed in the degree of crystalline lens tilt before and after ICL implantation (2.08 ± 0.07 vs 1.94 ± 0.08 degrees, <i>P</i> = .179), with both tilting temporally and demonstrating a significant positive correlation (<i>r</i> = 0.785, <i>P</i> < .001). The degree of postoperative crystalline lens decentration was significantly reduced compared to that before implantation (201 ± 64 vs 192 ± 92 µm, <i>P</i> = .0073), with the decentration predominantly in the upward direction, and demonstrating a strong positive correlation (<i>r</i> = 0.637, <i>P</i> < .001). Additionally, ICL tilt exhibited a strong positive correlation with both preoperative and postoperative lens tilt (<i>r</i> = 0.687, <i>P</i> < .001; <i>r</i> = 0.613, <i>P</i> < .001), as well as with ICL decentration (<i>r</i> = 0.512, <i>P</i> = .001).</p><p><strong>Conclusions: </strong>SS-OCT combined with multi-task deep learning enables quantitative assessment of the spatial position of both the crystalline lens and ICL. Short-term observations indicate that ICL implantation impacts the position of the crystalline lens to varying extents. <b>[<i>J Refract Surg</i>. 2025;41(6):e569-e574.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 6","pages":"e569-e574"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144248382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}