Journal of refractive surgery最新文献

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Sterile Anterior Segment Inflammation Associated With Sulcus-Supported Phakic IOL Surgery. 沟支撑型晶状体人工晶状体手术相关的无菌前段炎症。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-03-01 DOI: 10.3928/1081597X-20260112-04
Yishan Qian, Lingling Niu, Xianglong Yi, Hongyu Kong, Jia Huang, Zhiqiang Yu, Peijun Yao, Ti Wang, Meiyan Li, Xingtao Zhou, Xiaoying Wang
{"title":"Sterile Anterior Segment Inflammation Associated With Sulcus-Supported Phakic IOL Surgery.","authors":"Yishan Qian, Lingling Niu, Xianglong Yi, Hongyu Kong, Jia Huang, Zhiqiang Yu, Peijun Yao, Ti Wang, Meiyan Li, Xingtao Zhou, Xiaoying Wang","doi":"10.3928/1081597X-20260112-04","DOIUrl":"10.3928/1081597X-20260112-04","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the incidence, presentation, and outcomes of sterile anterior segment inflammation following sulcus-supported phakic IOL implantation (SASI-pIOL).</p><p><strong>Methods: </strong>The retrospective case series included consecutive patients diagnosed as having SASI-pIOL (early-onset: ⩽ 7 days; late-onset: > 7 days postoperatively) between July 2023 and July 2024 at two tertiary centers in China. All patients were followed up for at least 6 months after diagnosis.</p><p><strong>Results: </strong>SASI-pIOL occurred in 39 eyes (0.26%) out of 15,209 pIOL surgeries. Early-onset cases accounted for 26 eyes (66.7%), and late-onset for 13 eyes (33.3%). Anterior chamber inflammation and pIOL surface white deposits resolved completely with topical steroids. No eye lost one or more Snellen lines in corrected distance visual acuity. No significant changes were observed in intraocular pressure or endothelial cell density compared to baseline. Recurrence of white deposits on the pIOL occurred in 11 eyes (42.3%) in the early-onset group and 6 eyes (54.5%) in the late-onset group. A significant difference was observed in the proportion of early-onset versus late-onset SASI-pIOL cases relative to ophthalmic viscosurgical device use (<i>P</i> < .001, Fisher's exact test).</p><p><strong>Conclusions: </strong>SASI-pIOL is uncommon, responds well to topical corticosteroids, and is associated with favorable visual outcomes, yet requires long-term monitoring due to a notable recurrence rate.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 3","pages":"e248-e256"},"PeriodicalIF":2.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of a Regression Formula to Predict Post-DMEK Keratometry and Improve IOL Power Calculation in Eyes Undergoing Phacoemulsification Combined With DMEK. DMEK联合超声乳化术后角膜度数预测及人工晶状体度数计算的回归公式验证。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-03-01 DOI: 10.3928/1081597X-20260112-05
Arianna Grendele, Karl Anders Knutsson, Kenneth J Hoffer, Giorgio Paganoni, Giorgio Lari, Carlotta Senni, Catarina Coutinho, Giacomo Savini
{"title":"Validation of a Regression Formula to Predict Post-DMEK Keratometry and Improve IOL Power Calculation in Eyes Undergoing Phacoemulsification Combined With DMEK.","authors":"Arianna Grendele, Karl Anders Knutsson, Kenneth J Hoffer, Giorgio Paganoni, Giorgio Lari, Carlotta Senni, Catarina Coutinho, Giacomo Savini","doi":"10.3928/1081597X-20260112-05","DOIUrl":"10.3928/1081597X-20260112-05","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the refractive accuracy of intraocular lens (IOL) power calculation in patients with Fuchs' endothelial dystrophy (FED) undergoing Descemet membrane endothelial keratoplasty (DMEK) combined with cataract surgery (triple DMEK), using an estimated keratometry value developed to minimize postoperative hyperopic outcomes.</p><p><strong>Methods: </strong>Thirty-one eyes of 31 phakic patients with FED and corneal edema undergoing triple DMEK were included. Preoperative assessments included optical biometry with the IOLMaster 700 (Carl Zeiss Meditec AG) and anterior segment optical coherence tomography (AS-OCT) with the MS-39. IOL power was calculated with 7 formulas (Barrett Universal II, EVO 2.0, Haigis, Hoffer QST, Holladay 1, Kane, and SRK/T) using both the measured preoperative keratometry and an estimated postoperative keratometry derived from a regression model (ΔK = 5.281 + 1.926 × R<sub>ant</sub> - 1.493 × R<sub>post</sub>). The spherical equivalent prediction error (SEQ-PE) was assessed at 6 months and analyzed using Eyetemis.</p><p><strong>Results: </strong>Substituting the estimated keratometry for the measured keratometry halved the hyperopic SEQ-PE across all formulas (from > +1.00 D to approximately +0.50 D), improving both trueness and overall accuracy. Although precision (ie, standard deviation) also improved, this change was not statistically significant. The formulas achieving the highest percentage of eyes with SEQ-PE less than ±0.50 D were Haigis and EVO 2.0 (52% each), followed by Hoffer QST (48%).</p><p><strong>Conclusions: </strong>Using estimated keratometry values derived from a regression model significantly improves refractive outcomes in patients with FED undergoing triple DMEK, reducing the risk of hyperopic surprises following surgery.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 3","pages":"e257-e263"},"PeriodicalIF":2.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodal Predictive Modeling for Visual Quality Recovery After Keratorefractive Lenticule Extraction. 屈光性角膜透镜提取后视觉质量恢复的多模态预测模型。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-03-01 DOI: 10.3928/1081597X-20260112-03
Qi Wan, Li Chen, Jing Tang, Ying-Ping Deng, Ke Ma
{"title":"Multimodal Predictive Modeling for Visual Quality Recovery After Keratorefractive Lenticule Extraction.","authors":"Qi Wan, Li Chen, Jing Tang, Ying-Ping Deng, Ke Ma","doi":"10.3928/1081597X-20260112-03","DOIUrl":"10.3928/1081597X-20260112-03","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the factors influencing visual quality recovery after keratorefractive lenticule extraction (KLEx) and to establish a predictive model for postoperative visual quality using multimodal data integration.</p><p><strong>Methods: </strong>A prospective, non-interventional single-center study was conducted on 210 eyes from 105 myopic patients undergoing KLEx surgery. Preoperative and postoperative visual quality was assessed using the Objective Scatter Index (OSI). High-precision segmentation of posterior lenticule scanning images was performed using a U-net-based deep learning model to extract radiomics features. These features, along with clinical data, surgical parameters, corneal topography, and biomechanics, were integrated into machine learning models for predicting OSI at 1 day and 1 week postoperatively.</p><p><strong>Results: </strong>The study found that 30.95% (65/210) of eyes experienced poor early visual recovery. Significant differences in spherical equivalent, corneal curvature, and cutting depth were observed between good and poor visual quality groups. The ExtraTrees model demonstrated high efficacy in predicting OSI on the first postoperative day (area under the curve [AUC] = 0.96), whereas the AdaBoost model excelled at 1 week (AUC = 0.99). Regression models RidgeCV and LassoLarsIC performed best for predicting OSI values at 1 day and 1 week, respectively. Radiomics features such as original topology Gaussian Curvature Min and original gldm Dependence Variance were significantly correlated with the OSI.</p><p><strong>Conclusions: </strong>The study establishes a predictive framework that integrates intraoperative scanning image features, corneal biomechanics, and densitometry parameters, offering a quantitative basis for personalized surgical planning. The synergistic use of radiomics and clinical parameters can pre-identify high-risk patients, optimize surgical settings, and improve postoperative visual quality.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 3","pages":"e235-e247"},"PeriodicalIF":2.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Anterior Capsule Polishing on the Capsule-IOL Complex in Patients With Normal Axial Length: A Prospective Randomized Controlled Trial. 前囊抛光对正常眼轴长度患者囊-人工晶体复合体的影响:一项前瞻性随机对照试验。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-03-01 DOI: 10.3928/1081597X-20260112-10
Wenkai Huang, Chenyuan Zhu, Xuechuan Miao, Er Mo, Zhexuan Liu, Jin Li, Junyong Cai
{"title":"Effect of Anterior Capsule Polishing on the Capsule-IOL Complex in Patients With Normal Axial Length: A Prospective Randomized Controlled Trial.","authors":"Wenkai Huang, Chenyuan Zhu, Xuechuan Miao, Er Mo, Zhexuan Liu, Jin Li, Junyong Cai","doi":"10.3928/1081597X-20260112-10","DOIUrl":"10.3928/1081597X-20260112-10","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effect of anterior capsule polishing (ACP) on postoperative formation of the capsule-intraocular lens (C-IOL) complex in patients with cataract who have normal axial length.</p><p><strong>Methods: </strong>In this prospective randomized controlled trial, patients were assigned to either 360° ACP or no polishing. Primary outcomes (capsular bend index [CBI], adhesion index [AI], and continuous curvilinear capsulorhexis diameter [CCCD]) and secondary outcomes (IOL tilt and decentration) were quantitatively assessed at 1 week, 1 month, and 3 months postoperatively using 14-meridian swept-source optical coherence tomography (SS-OCT) (CASIA 2; Tomey). Additional secondary outcomes were root mean square (RMS), corrected distance visual acuity (CDVA), and spherical equivalent refraction (SER).</p><p><strong>Results: </strong>Forty-five eyes were enrolled (23 ACP, 22 control), and 40 (20 per group) completed a 3-month follow-up. At 3 months, the ACP group showed lower CBI (3.16 vs 3.68; <i>P</i> = .001) and AI (0.00 vs 0.32; <i>P</i> = .023), larger CCCD (5.30 vs 5.04 mm; <i>P</i> = .025), and less CCCD contraction (0.11 vs 0.22 mm; <i>P</i> = .034). Between-visit changes in CBI and AI did not differ between groups. Vertical tilt and its RMS were greater with ACP (<i>P</i> = .012 and .009, respectively), whereas horizontal tilt, decentration, CDVA, and SER were comparable.</p><p><strong>Conclusions: </strong>ACP slows early C-IOL structural maturation (reduced capsular-bend kinetics and delayed capsule-IOL adhesion) without compromising early refractive stability and stabilizes the capsulorhexis, but increases vertical IOL tilt. These findings support selective use in eyes prone to contraction and caution when precise IOL alignment is required.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 3","pages":"e264-e272"},"PeriodicalIF":2.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum for "The Impact of Different Rose Bengal Formulations on Corneal Thickness and the Efficacy of Rose Bengal/Green Light Corneal Cross-Linking in the Rabbit Eye". “不同孟加拉玫瑰配方对兔眼角膜厚度的影响以及孟加拉玫瑰/绿光角膜交联的功效”的勘误。
IF 3 3区 医学
Journal of refractive surgery Pub Date : 2026-02-01 DOI: 10.3928/1081597X-20260108-01
{"title":"Erratum for \"The Impact of Different Rose Bengal Formulations on Corneal Thickness and the Efficacy of Rose Bengal/Green Light Corneal Cross-Linking in the Rabbit Eye\".","authors":"","doi":"10.3928/1081597X-20260108-01","DOIUrl":"https://doi.org/10.3928/1081597X-20260108-01","url":null,"abstract":"","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 2","pages":"e196"},"PeriodicalIF":3.0,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Texture-based Analysis of Corneal Dynamics for the Detection of Forme Fruste Keratoconus. 基于纹理的角膜动力学分析检测结痂圆锥角膜。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-02-01 DOI: 10.3928/1081597X-20251125-02
Shenglong Luo, Kuangching Lin, Xuefei Li, Xin Zhang, Lvfu He, Ahmed Elsheikh, Fangjun Bao, Meixiao Shen, Shihao Chen, Fan Lu, Junjie Wang
{"title":"Texture-based Analysis of Corneal Dynamics for the Detection of Forme Fruste Keratoconus.","authors":"Shenglong Luo, Kuangching Lin, Xuefei Li, Xin Zhang, Lvfu He, Ahmed Elsheikh, Fangjun Bao, Meixiao Shen, Shihao Chen, Fan Lu, Junjie Wang","doi":"10.3928/1081597X-20251125-02","DOIUrl":"10.3928/1081597X-20251125-02","url":null,"abstract":"<p><strong>Purpose: </strong>To propose CVS-omics, a radiomics framework using Corvis ST (CVS) (Oculus Optikgeräte GmbH) imaging and machine learning, for precise identification of forme fruste keratoconus (FFKC), a subtle corneal condition often undetected by conventional diagnostics.</p><p><strong>Methods: </strong>A total of 410 eyes were evaluated, including 265 normal eyes and 145 FFKC eyes. Texture features through radiomics were extracted from CVS images acquired at three key deformation phases: initial state, first applanation, and maximum deformation. These features were used to train three machine learning models (Random Forest [Minitab, Inc], C5.0 [RuleQuest Research], and XGBoost (extreme Gradient Boosting) on 328 eyes, with testing conducted on 82 eyes. Diagnostic performance was evaluated using receiver operating characteristic (ROC) analysis and compared with conventional biomechanical parameters.</p><p><strong>Results: </strong>The CVS-omics Random Forest model achieved superior diagnostic performance (area under the curve (AUC) = 0.989, sensitivity = 0.931, specificity = 0.962, accuracy = 0.951), significantly outperforming traditional CVS parameters (best AUC = 0.764). Models trained on features from three deformation phases showed higher diagnostic accuracy than those based on a single phase. Other models demonstrated high generalizability of dynamic radiomics features (XGBoost and C5.0 AUC > 0.83).</p><p><strong>Conclusions: </strong>CVS-omics effectively detects subtle characteristic alterations in FFKC eyes with superior accuracy compared to conventional biomechanical parameters. This texture feature approach shows promise as a non-invasive clinical tool for FFKC detection and timely intervention.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 2","pages":"e141-e150"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare but Serious: Infectious Keratitis After Femtosecond Laser-Assisted Arcuate Keratotomies in Cataract Surgery: A Case Series and Review of Literature. 罕见但严重:飞秒激光辅助白内障手术后的感染性角膜炎:病例系列及文献回顾。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-02-01 DOI: 10.3928/1081597X-20251125-01
Daniel David, Michael Mimouni, Guy Kleinmann, Or Gil, Lee Nussbaum, Shalev Fried, Irina S Barequet
{"title":"Rare but Serious: Infectious Keratitis After Femtosecond Laser-Assisted Arcuate Keratotomies in Cataract Surgery: A Case Series and Review of Literature.","authors":"Daniel David, Michael Mimouni, Guy Kleinmann, Or Gil, Lee Nussbaum, Shalev Fried, Irina S Barequet","doi":"10.3928/1081597X-20251125-01","DOIUrl":"10.3928/1081597X-20251125-01","url":null,"abstract":"<p><strong>Purpose: </strong>To present five cases of infectious keratitis following femtosecond laser-assisted cataract surgery combined with laser arcuate keratotomies (FLACS-AK).</p><p><strong>Methods: </strong>This was a retrospective review of the medical records of five patients who developed infectious keratitis after FLACS-AK, including medical history, clinical findings, surgical details, microbiological culture results, and imaging. Review of the literature revealed only two other published cases describing infectious keratitis following FLACS-AK.</p><p><strong>Results: </strong>All patients underwent uneventful FLACS-AK in both eyes and later developed unilateral infectious keratitis at the arcuate keratotomy incision. One patient developed an early-onset, fulminant infection with cultures positive for <i>Pseudomonas aeruginosa</i>. Two patients presented with late-onset, milder infections, with negative culture results. Two patients developed a very late-onset infection due to <i>P. aeruginosa</i>, with one of them requiring surgical intervention. All patients were also treated with fortified antibiotics. Four of five patients had good clinical and visual outcomes, whereas one patient suffered from devastating results.</p><p><strong>Conclusions: </strong>Infectious keratitis following FLACS-AK is a rare but potentially sight-threatening complication with variable onset and severity. Penetrating arcuate keratotomies may pose a higher risk of infection compared to intrastromal incisions, underscoring the need for careful surgical planning and long-term postoperative surveillance. Surgeons should therefore consider performing an intrastromal incision or, when applicable, a different method for arcuate correction.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 2","pages":"e189-e195"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal Allograft for Near Vision Improvement in Emmetropic Presbyopia: 4-Year Safety and Efficacy Results From a Prospective European Multicenter Clinical Trial. 同种异体角膜移植改善近视老花眼的近视力:来自欧洲前瞻性多中心临床试验的4年安全性和有效性结果。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-02-01 DOI: 10.3928/1081597X-20251202-02
Aylin Kilic, Arthur Cummings, Pavel Stodulka, Sheraz Daya, Samer Hamada, Marine Gobbe, David Muller, Michael Mrochen
{"title":"Corneal Allograft for Near Vision Improvement in Emmetropic Presbyopia: 4-Year Safety and Efficacy Results From a Prospective European Multicenter Clinical Trial.","authors":"Aylin Kilic, Arthur Cummings, Pavel Stodulka, Sheraz Daya, Samer Hamada, Marine Gobbe, David Muller, Michael Mrochen","doi":"10.3928/1081597X-20251202-02","DOIUrl":"10.3928/1081597X-20251202-02","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate both short- and long-term safety and effectiveness of intrastromal implantation of the corneal inlay for providing near vision in patients with presbyopia.</p><p><strong>Methods: </strong>This multicenter, prospective study included adults who had emmetropia (45 to 65 years old) with astigmatism of 0.75 diopters (D) or less and a near addition of 1.75 D or greater. After creation of a femtosecond laser flap, the sterile corneal inlay allograft was implanted on the stromal bed of the non-dominant eye and centered over the light-constricted pupil. Refraction and monocular and binocular visual acuity at distance, intermediate, and near were measured at the 6-month, 12-month, and 4-year visits.</p><p><strong>Results: </strong>A total of 101 patients were treated, with 94 available at 6 months and 71 at 4 years. At 6 months, mean binocular uncorrected distance (UDVA), intermediate (UIVA), and near (UNVA) visual acuity were -0.11 ± 0.07, 0.09 ± 0.18, and 0.03 ± 0.11 logarithm of the minimum angle of resolution, respectively. Binocularly, UDVA was 20/20 or better in 95.7% of patients at 6 months and 94.4% at 4 years; UNVA was 20/40 or better in 98.9% of patients at 6 months and 98.6% at 4 years compared to 16% preoperatively. Mean spherical equivalent was -0.69 ± 0.50 D at 6 months and -0.52 ± 0.64 D at 4 years, with no increased astigmatism. Monocular distance-corrected near visual acuity was 20/40 or better in 88.3% of treated eyes at 6 months and 78.9% at 4 years. At 6 months, all corneas were clear. The inlay was explanted in 3 eyes before 6 months due to anisometropia intolerance; all recovered without sequelae.</p><p><strong>Conclusions: </strong>Implantation of a sterile allograft stromal inlay in the non-dominant eyes of patients with emmetropic presbyopia was safe and effective in improving near and intermediate vision while maintaining distance vision up to 4 years after surgery.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 2","pages":"e100-e107"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
VISULYZE: A Novel Nomogram Tool for Optimizing Refractive Outcomes in SMILE Surgery. VISULYZE:一种优化SMILE手术屈光效果的新型Nomogram工具。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-02-01 DOI: 10.3928/1081597X-20251217-05
Juehan Li, Enze Liu, Haixia Ji, Nannan Gao, Mu Zhang, Xinliang Cheng, Ying Yu
{"title":"VISULYZE: A Novel Nomogram Tool for Optimizing Refractive Outcomes in SMILE Surgery.","authors":"Juehan Li, Enze Liu, Haixia Ji, Nannan Gao, Mu Zhang, Xinliang Cheng, Ying Yu","doi":"10.3928/1081597X-20251217-05","DOIUrl":"10.3928/1081597X-20251217-05","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate a new nomogram technique, VISULYZE (Carl Zeiss Meditec AG), in small incision lenticule extraction (SMILE) surgery for treatment of myopia and myopic astigmatism.</p><p><strong>Methods: </strong>This was a prospective, nonrandomized, controlled study. VISULYZE is a specialized software platform for refractive surgeons that integrates patient data analysis with personalized nomogram generation. A total of 108 ideal eye examples (spherical equivalent [SE] within ±0.50 diopters [D] at 3 months postoperatively) were used for creation of the nomogram by VISULYZE. Another 100 eyes from 50 patients were enrolled in the SMILE 3.0 group (traditional nomogram), and 107 eyes from 55 patients in the SMILE 4.0 group (nomogram set by VISULYZE). All patients were followed up for 3 months, with monitoring of uncorrected distance visual acuity, corrected distance visual acuity, spherical equivalent, higher order aberrations, and the preoperative and postoperative complications.</p><p><strong>Results: </strong>A nomogram was derived from a quadratic regression formula generated by VISULYZE to adjust the SE target. The safety of refractive outcome did not differ significantly in the two groups at the 3-month follow-up visit (<i>P</i> > .05). The efficacy index in the SMILE 4.0 group (1.11 ± 0.11) was significantly higher than in the SMILE 3.0 group (1.06 ± 0.14) (<i>P</i> < .05). In the SMILE 4.0 group, the predictability of error was 97% within ±0.50 D and 100% within ±1.00 D, compared with 81% and 99%, respectively, in the SMILE 3.0 group. The error of SE correction was -0.12 ± 0.30 and -0.36 ± 0.27 D for the SMILE 4.0 and SMILE 3.0 groups, respectively. There was no significant difference between the two groups in the root mean square values of total higher order aberrations, coma, trefoil, and spherical aberration at both 1 and 3 months postoperatively (<i>P</i> > .05).</p><p><strong>Conclusions: </strong>The nomogram generated by VISULYZE demonstrated comparable safety outcomes to a traditional nomogram while achieving significantly superior efficacy. This advanced nomogram technology also improves refractive prediction accuracy for SMILE procedures.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 2","pages":"e180-e188"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central Vault and Anterior Chamber Angle Measurements After ICL Implantation: Repeatability and Reproducibility With a New Full-Range SS-OCT and Agreement With an Anterior Segment SS-OCT. ICL植入后中央穹窿和前房角度测量:新的全范围SS-OCT的重复性和再现性以及与前段SS-OCT的一致性。
IF 2.9 3区 医学
Journal of refractive surgery Pub Date : 2026-02-01 DOI: 10.3928/1081597X-20251217-04
Chak Seng Lei, Qinghao Meng, Xinyu Jiang, Rui Ning, Xun Chen, Mingrui Cheng, Yadi Lei, Xingtao Zhou, Xiaoying Wang, Jinhai Huang
{"title":"Central Vault and Anterior Chamber Angle Measurements After ICL Implantation: Repeatability and Reproducibility With a New Full-Range SS-OCT and Agreement With an Anterior Segment SS-OCT.","authors":"Chak Seng Lei, Qinghao Meng, Xinyu Jiang, Rui Ning, Xun Chen, Mingrui Cheng, Yadi Lei, Xingtao Zhou, Xiaoying Wang, Jinhai Huang","doi":"10.3928/1081597X-20251217-04","DOIUrl":"10.3928/1081597X-20251217-04","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the intraobserver repeatability and interobserver reproducibility of central vault and anterior chamber angle (ACA) measurements obtained with the YG-100K (TowardPi Medical Technology Ltd), a new full-range swept-source optical coherence tomography (SS-OCT) device, in eyes after Implantable Collamer Lens (ICL) implantation, and to evaluate their agreement with the established CASIA 2 anterior segment SS-OCT device (Tomey).</p><p><strong>Methods: </strong>This prospective study enrolled 78 myopic eyes (78 patients) after ICL implantation. Central vault, trabecular iris angle (TIA), angle opening distance, and trabecular iris space area were measured using the YG-100K and CASIA 2 devices. The automatic software of each device identified scleral spur and angle recess positions for ACA measurements. Repeatability and reproducibility were assessed using the within-subject standard deviation, test-retest repeatability, coefficient of variation (CoV), and intraclass correlation coefficient (ICC). Inter-device agreement was analyzed using paired <i>t</i>-tests and Bland-Altman plots.</p><p><strong>Results: </strong>The YG-100K demonstrated good to excellent repeatability and reproducibility for vault and ACA measurements, with CoVs ranging from 2.35% to 8.17% and ICCs between 0.888 and 0.997. The vault measured by the YG-100K was 15.38 ± 22.38 µm higher than the CASIA 2, with 95% limits of agreement (LoA) ranging from -28.48 to 59.24 µm. ACA measurements, except for TIA500, showed significant differences between devices, accompanied by wide 95% LoA ranges.</p><p><strong>Conclusions: </strong>The YG-100K provided reliable repeatability and reproducibility measurements in eyes after ICL implantation. Vault measurements showed good agreement with the CASIA 2, whereas discrepancies in ACA measurements indicated that these parameters should not be used interchangeably between devices.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 2","pages":"e161-e170"},"PeriodicalIF":2.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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