Jad F. Assaf, MD, Hady Yazbeck, MD, Dan Z. Reinstein, MD, MA(Cantab), FRCOphth, Timothy J. Archer, MA(Oxon), DipCompSci(Cantab), PhD, Juan Arbelaez, MD, Yara Bteich, MD, Maria Clara Arbelaez, MD, Anthony Abou Mrad, MD, Shady T. Awwad, MD
{"title":"Enhancing the Automated Detection of Implantable Collamer Lens Vault Using Generative Adversarial Networks and Synthetic Data on Optical Coherence Tomography","authors":"Jad F. Assaf, MD, Hady Yazbeck, MD, Dan Z. Reinstein, MD, MA(Cantab), FRCOphth, Timothy J. Archer, MA(Oxon), DipCompSci(Cantab), PhD, Juan Arbelaez, MD, Yara Bteich, MD, Maria Clara Arbelaez, MD, Anthony Abou Mrad, MD, Shady T. Awwad, MD","doi":"10.3928/1081597x-20240214-01","DOIUrl":"https://doi.org/10.3928/1081597x-20240214-01","url":null,"abstract":"<section><h3>Purpose:</h3><p>To investigate the efficacy of incorporating Generative Adversarial Network (GAN) and synthetic images in enhancing the performance of a convolutional neural network (CNN) for automated estimation of Implantable Collamer Lens (ICL) vault using anterior segment optical coherence tomography (AS-OCT).</p></section><section><h3>Methods:</h3><p>This study was a retrospective evaluation using synthetic data and real patient images in a deep learning framework. Synthetic ICL AS-OCT scans were generated using GANs and a secondary image editing algorithm, creating approximately 100,000 synthetic images. These were used alongside real patient scans to train a CNN for estimating ICL vault distance. The model's performance was evaluated using statistical metrics such as mean absolute percentage error (MAPE), mean absolute error (MAE), root mean squared error (RMSE), and coefficient of determination (<i>R</i><sup>2</sup>) for the estimation of ICL vault distance.</p></section><section><h3>Results:</h3><p>The study analyzed 4,557 AS-OCT B-scans from 138 eyes of 103 patients for training. An independent, retrospectively collected dataset of 2,454 AS-OCT images from 88 eyes of 56 patients, used prospectively for evaluation, served as the test set. When trained solely on real images, the CNN achieved a MAPE of 15.31%, MAE of 44.68 µm, and RMSE of 63.3 µm. However, with the inclusion of GAN-generated and algorithmically edited synthetic images, the performance significantly improved, achieving a MAPE of 8.09%, MAE of 24.83 µm, and RMSE of 32.26 µm. The <i>R</i><sup>2</sup> value was +0.98, indicating a strong positive correlation between actual and predicted ICL vault distances (<i>P</i> < .01). No statistically significant difference was observed between measured and predicted vault values (<i>P</i> = .58).</p></section><section><h3>Conclusions:</h3><p>The integration of GAN-generated and edited synthetic images substantially enhanced ICL vault estimation, demonstrating the efficacy of GANs and synthetic data in enhancing OCT image analysis accuracy. This model not only shows potential for assisting postoperative ICL evaluations, but also for improving OCT automation when data paucity is an issue.</p><p><strong>[<i>J Refract Surg</i>. 2024;40(4):e199–e207.]</strong></p></section>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"50 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140570236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Changes in Corneal Epithelial Thickness in Different Areas After Femtosecond Laser–Assisted LASIK in Patients With High Astigmatism","authors":"Anqi Li, MD, Zhichao Liu, MD, Meng Lin, MD, Qianwen Gong, MD, PhD, Linzhi Wei, MD, Fan Lu, MD, OD, Liang Hu, MD, OD","doi":"10.3928/1081597x-20240311-04","DOIUrl":"https://doi.org/10.3928/1081597x-20240311-04","url":null,"abstract":"<section><h3>Purpose:</h3><p>To explore changes in corneal epithelial thickness (CET) after femtosecond laser–assisted laser in situ keratomileusis in patients with high astigmatism.</p></section><section><h3>Methods:</h3><p>CET was measured at every intersection of the concentric circles and specific axes using AngioVue optical coherence tomography (Angio-OCT) preoperatively and 1 month postoperatively. The average thickness of corneal central, paracentral, and peripheral regions was the mean of the points within the central 2, 2 to 5, and 5 to 7 mm areas, respectively. Correlation analysis was performed to investigate the association between CET along different axes and other preoperative and postoperative parameters.</p></section><section><h3>Results:</h3><p>Forty-two eyes of 28 patients were included. CET along the astigmatic (K1) and perpendicular (K2) axes in the central and paracentral areas increased (<i>P</i> < .001), whereas that along the K2 axis decreased in the peripheral area 1 month postoperatively (<i>P</i> = .001). The amount of CET change in the peripheral area between the K1 and K2 axes was significantly different (<i>P</i> < .001). In the central area, the change in CET along the K2 axis was positively correlated with ablation depth (<i>r</i> = 0.315, <i>P</i> = .042) and negatively with refractive power after surgery (<i>r</i> = −0.347, <i>P</i> = .024). In the peripheral area, the changes in CET along both K1 and K2 axes were negatively correlated with ablation depth (<i>r</i> = −0.431, <i>P</i> = .004; <i>r</i> = −0.387, <i>P</i> = .011, respectively).</p></section><section><h3>Conclusions:</h3><p>Epithelial modeling differed between the different astigmatism axes after refractive surgery. The compensatory response of the corneal epithelium is more pronounced along the steeper axis.</p><p><strong>[<i>J Refract Surg</i>. 2024;40(4):e239–e244.]</strong></p></section>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"116 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Visual Quality Assessment After FS-LASIK Using Customized Aspheric Ablation Profile for Age-Related Accommodation Deficiency Compensation","authors":"Ruiyu Zhang, MD, Yifei Yuan, MD, Yu Zhang, MD, Yueguo Chen, MD","doi":"10.3928/1081597x-20240311-05","DOIUrl":"https://doi.org/10.3928/1081597x-20240311-05","url":null,"abstract":"<section><h3>Purpose:</h3><p>To evaluate clinical outcomes and visual quality 12 months after femtosecond laser–assisted laser in situ keratomileusis (FS-LASIK) performed with the Custom-Q algorithm for correction of myopia with or without astigmatism and compensate for age-related accommodation deficiency.</p></section><section><h3>Methods:</h3><p>Patients who had Custom-Q FS-LASIK for myopia and myopic astigmatism with age-related accommodation deficiency were included in this retrospective study. Distance, intermediate, and near visual acuities, objective and subjective refractions, Q-factor, corneal higher order aberrations (HOAs), accommodation function, defocus curve, contrast sensitivity, and a subjective questionnaire assessing visual quality were evaluated 12 months postoperatively.</p></section><section><h3>Results:</h3><p>Clinical data of 43 cases were analyzed. The mean age was 42.02 ± 1.85 years (range: 40 to 48 years). At the 12-month follow-up visit, there were 43 (100%), 42 (97%), and 33 (77%) patients who achieved a binocular uncorrected distance, intermediate, and near visual acuity, respectively, better than 20/20 separately. Defocus curves revealed better distance vision in the dominant eyes, and the nondominant eyes performed better at intermediate and near vergence (<i>P</i> < .001). The Q-value and corneal spherical aberration coefficient were more positive in the dominant eyes than those in the nondominant eyes (<i>P</i> < .001). The accommodative amplitude and relative accommodation improved binocularly (<i>P</i> < .001). The questionnaire demonstrated high patient satisfaction with near vision, and no one reported having severe visual disturbance.</p></section><section><h3>Conclusions:</h3><p>For myopic patients with age-related accommodation deficiency, the Custom-Q algorithm proved to be an effective way to achieve acceptable near vision without compromising distance vision.</p><p><strong>[<i>J Refract Surg</i>. 2024;40(4):e245–e252.]</strong></p></section>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"34 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140570275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaofeng Zhu, MD, Shanshan Li, MM, Min Wang, MD, Wenbo Yao, BAppSc(Optom), Xinhui Huang, MM, Liquan Zhao, MD
{"title":"Effects of Topical 0.05% Cyclosporine A on Dry Eye Symptoms and Parameters Following Small Incision Lenticule Extraction","authors":"Xiaofeng Zhu, MD, Shanshan Li, MM, Min Wang, MD, Wenbo Yao, BAppSc(Optom), Xinhui Huang, MM, Liquan Zhao, MD","doi":"10.3928/1081597x-20240311-03","DOIUrl":"https://doi.org/10.3928/1081597x-20240311-03","url":null,"abstract":"<section><h3>Purpose:</h3><p>To evaluate the effects of topical 0.05% cyclosporine A on Ocular Surface Disease Index (OSDI) score and ocular surface parameters after small incision lenticule extraction (SMILE) for myopia.</p></section><section><h3>Methods:</h3><p>In this study, 151 patients who underwent SMILE were randomized into the control group (71 eyes) and the 0.05% cyclosporine A group (80 eyes). Both groups received standard treatment during the 1 month after SMILE. Over the next 3 months, The control group continued standard therapy (0.3% sodium hyaluronate) and the 0.05% cyclosporine A group received additional 0.05% cyclosporine A. OSDI total and subscale scores, non-invasive tear break-up time (NIBUT), tear lipid layer thickness (LLT), and tear meniscus height (TMH) were assessed preoperatively and postoperatively.</p></section><section><h3>Results:</h3><p>Compared to baseline, the OSDI scores significantly increased in both groups (<i>P</i> < .001). The 0.05% cyclosporine A group exhibited lower OSDI total scores after administering 0.05% cyclosporine A versus the control group (<i>P</i> = .026). At 1 month of follow-up, NIBUT, LLT, and TMH values significantly decreased in both groups compared to baseline (<i>P</i> < .05). The 0.05% cyclosporine A group exhibited higher NIBUT, LLT, and TMH versus the control group, returning to preoperative values after 2 months. Overall, the OSDI total score and NIBUT values during follow-up were not significantly different between the two groups; however, the LLT and TMH values were significantly different between the two groups (<i>P</i> < .001 and .041, respectively) by repeated measures analysis of variance.</p></section><section><h3>Conclusions:</h3><p>Topical 0.05% cyclosporine A was effective in relieving subjective dry eye symptoms and maintaining ocular surface stability in the early postoperative period of SMILE.</p><p><strong>[<i>J Refract Surg</i>. 2024;40(4):e229–e238.]</strong></p></section>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"205 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catarina P. Coutinho, MSc, Domenico Schiano-Lomoriello, MD, Cosimo Mazzotta, MD, PhD, Marco Ferrise, MD, Kenneth J. Hoffer, MD, Filomena J. Ribeiro, MD, PhD, João Mendanha Dias, PhD, Giacomo Savini, MD
{"title":"Differences Between Simulated Keratometry and Total Corneal Power in Eyes With Keratoconus and a Formula to Improve IOL Power Calculation Results","authors":"Catarina P. Coutinho, MSc, Domenico Schiano-Lomoriello, MD, Cosimo Mazzotta, MD, PhD, Marco Ferrise, MD, Kenneth J. Hoffer, MD, Filomena J. Ribeiro, MD, PhD, João Mendanha Dias, PhD, Giacomo Savini, MD","doi":"10.3928/1081597x-20240311-06","DOIUrl":"https://doi.org/10.3928/1081597x-20240311-06","url":null,"abstract":"<section><h3>Purpose:</h3><p>To compare simulated keratometry (SimK) and total corneal power (TCP) in keratoconic eyes, to determine whether the differences are systematic and predictable and to evaluate an adjusted TCP-based formula for intraocular lens (IOL) power calculation.</p></section><section><h3>Methods:</h3><p>In a consecutive series of keratoconic eyes, measurements of SimK, TCP, posterior keratometry, and anterior and posterior corneal asphericities (Q-values) were retrospectively collected. The difference between SimK and TCP was linearly correlated to the biometric parameters. In a separate sample of keratoconic eyes that had undergone cataract surgery, IOL power was calculated with the Barrett Universal II, Hoffer QST, Holladay 1, Kane, and SRK/T formulas using the SimK and an adjusted TCP power. The respective prediction errors were calculated.</p></section><section><h3>Results:</h3><p>A total of 382 keratoconic eyes (271 patients) were enrolled. An increasing overestimation of SimK by TCP was detected from stage I to III, with a significant correlation between the SimK and TCP difference and SimK in the whole sample (<i>P</i> < .0001, <i>r</i><sup>2</sup> = 0.1322). Approximately 7% of cases presented an underestimation of SimK by TCP. IOL power calculation with the adjusted TCP improved outcomes, achieving a maximum of 80% of eyes with a prediction error within ±0.50 diopters with the Hoffer QST, Holladay 1, and Kane formulas.</p></section><section><h3>Conclusions:</h3><p>Overall, SimK overestimated TCP. Such a difference could not be predicted by any variable. The proposed TCP-adjustment formula (TCP<sub>adj</sub> = TCP + 0.56 diopters) in keratoconic eyes for IOL power calculation might be valuable for improving refractive outcomes.</p><p><strong>[<i>J Refract Surg</i>. 2024;40(4):e253–e259.]</strong></p></section>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"41 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the Agreement Between a New Pyramid Wavefront Sensor Aberrometer and Scheiner-Smirnov Aberrometers","authors":"Yizhou Yang, MD, Rui Ning, MD, Shuoyu Xu, MD, Jinxuan Xiahou, MD, Jiawei Li, MD, Giacomo Savini, MD, PhD, Domenico Schiano-Lomoriello, MD, Xingtao Zhou, MD, PhD, Jinhai Huang, MD, PhD","doi":"10.3928/1081597x-20240311-02","DOIUrl":"https://doi.org/10.3928/1081597x-20240311-02","url":null,"abstract":"<section><h3>Purpose:</h3><p>To assess agreement between a new aberrometer (Osiris-T; CSO) employing pyramid wavefront sensor technique and Scheiner-Smirnov aberrometer (OPD-Scan III; Nidek) on measuring ocular, corneal, and internal aberrations in healthy participants.</p></section><section><h3>Methods:</h3><p>The measurements were conducted three times consecutively by an experienced examiner. The total root mean square (RMS) aberrations, higher order aberration RMS, coma Z<sub>3</sub><sup>±1</sup>, trefoil Z<sub>3</sub><sup>±3</sup>, spherical aberration Z<sub>4</sub><sup>0</sup><sub>,</sub> and astigmatism II Z<sub>4</sub><sup>±2</sup> up to 7th order were exported in both 4-and 6-mm pupil zones. The parameters between the two devices were statistically compared using the paired <i>t</i>-test, and the differences assessed with Bland-Altman plots and 95% limits of agreement.</p></section><section><h3>Results:</h3><p>This prospective study included 70 right eyes of 70 healthy participants with an average age of 25.94 ± 6.59 years (range: 18 to 47 years). The mean difference in the two devices ranged from 0.01 µm for astigmatism II Z<sub>4</sub><sup>±2</sup> to 0.63 µm for total RMS in 4 mm and from 0.01 to 1.41 µm in 6-mm pupil size. The Bland-Altman analysis of ocular, corneal, and internal aberrations indicated high agreement between the two devices and the maximum absolute values for 95% limits of agreement ranged from 0.03 to 1.06 µm for 4-mm pupil diameters and 0.12 to 1.13 µm for 6-mm pupil diameters.</p></section><section><h3>Conclusions:</h3><p>The newly developed pyramid wavefront sensor technique aberrometer demonstrated a high agreement with a Scheiner-Smirnov aberrometer when measuring ocular, corneal, and internal aberrations in healthy participants. Thus, the two aberrometers may be considered interchangeable for clinical applications.</p><p><strong>[<i>J Refract Surg</i>. 2024;40(4):e218–e228.]</strong></p></section>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"27 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introspection","authors":"Adrian Muñoz-Espouy","doi":"10.3928/1081597x-20240227-01","DOIUrl":"https://doi.org/10.3928/1081597x-20240227-01","url":null,"abstract":"<h2>Introduction</h2><p>Figure</p><section><figure><img alt=\"\" data-lg-src=\"/cms/asset/67b56a89-9e82-4132-aefe-595cd77a4bc0/10.3928_1081597x-20240227-01-fig1.jpg\" data-src=\"/cms/asset/b04c653c-a951-4b7b-a40b-be186907dc89/10.3928_1081597x-20240227-01-fig1.jpg\" src=\"/specs/ux3/releasedAssets/images/loader-7e60691fbe777356dc81ff6d223a82a6.gif\"/></figure></section><p>This artwork represents an aged man depicting with his glance, his attitude, and his skin the feeling of old age. It is a hard feeling that inspires our emotions even though the portrait is delicate and soft. However, the aggressiveness of aging is obvious in the painting. The degradation of the body, the spirit, and the expectations, together with memories of the past, are represented in the glance of this old man who is badly treated by age. His glance looks inside himself; he is observing his past and he feels no hopes for the future. A negative and analytical feeling with regret and sorrow is transmitted through his glance.</p><p>Adrian Muñoz-Espouy received the Miradas Award for the Emerging Artist Miradas de España, 2023.</p><p>Watercolor and graphite on paper and wood, 81 × 100 cm</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"219 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140617333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anterior Segment Biometry During Accommodation After Posterior Chamber Phakic Implantable Collamer Lens Implantation.","authors":"Guang-Ming Zhang, Li-Jun Zhao, Hua-Tao Xie, Ming-Feng Wu","doi":"10.3928/1081597X-20240212-01","DOIUrl":"10.3928/1081597X-20240212-01","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the dynamic changes in anterior segment parameters during accommodation following Implantable Collamer Lens (ICL) implantation with swept-source optical coherence tomography (SS-OCT).</p><p><strong>Methods: </strong>Under the accommodation of 0.00 diopters (D), 3.00 D, and maximum amplitude, SS-OCT was used to examine the anterior segment parameters, including ICL vault, ICL depth (the distance between the corneal endothelium and the posterior surface of ICL), crystalline lens thickness, anterior chamber depth, and various parameters of the anterior chamber angle, comprising angle opening distance, angle recess area, trabecular iris space area, and trabecular iris angle.</p><p><strong>Results: </strong>During accommodation, the ICL vault showed a significant decrease from baseline (536 ± 278 μm) to 3.00 D (522 ± 281 μm), followed by an increase from 3.00 D to maximum amplitude (548 ± 306 μm) (analysis of variance [ANOVA], <i>P</i> < .001). Four eyes (2.61%) exhibited a decrease in ICL vault to less than 100 μm (47 ± 32 μm) at maximum accommodation. The ICL depth decreased significantly as accommodation increased (ANOVA, <i>P</i> < .001). Crystalline lens thickness increased, whereas anterior chamber depth decreased during accommodation (ANOVA, <i>P</i> < .001). The anterior chamber angle widened during 3.00 D of accommodation but narrowed at maximum accommodation, leading to significant changes in the angle opening distance, angle recess area, trabecular iris space area, and trabecular iris angle during accommodation (ANOVA, <i>P</i> < .001 for all).</p><p><strong>Conclusions: </strong>The anterior segment, including ICL vault and anterior chamber angle, undergo significant dynamic changes during accommodation. These accommodative changes may require careful monitoring for the surgery design of ICL implantation. [<b><i>J Refract Surg</i></b>. <b>2024;40(3):e164-e172.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 3","pages":"e164-e172"},"PeriodicalIF":2.4,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Muzyka-Woźniak, Slawomir Woźniak, Grzegorz Łabuz
{"title":"Interchangeability in Automated Corneal Diameter Measurements Across Different Biometric Devices: A Systematic Review of Agreement Studies.","authors":"Maria Muzyka-Woźniak, Slawomir Woźniak, Grzegorz Łabuz","doi":"10.3928/1081597X-20240212-02","DOIUrl":"10.3928/1081597X-20240212-02","url":null,"abstract":"<p><strong>Purpose: </strong>To provide an up-to-date review of the agreement in automated white-to-white (WTW) measurement between the latest topographic and biometric devices.</p><p><strong>Methods: </strong>In this systematic review, PubMed, Web of Science, and Scopus databases were searched for articles published between 2017 and 2023, focusing on WTW agreement studies on adult, virgin eyes, with or without cataract and no other ocular comorbidities. Studies evaluating WTW measurements performed with autokeratometers, manual calipers, or manual image analysis were excluded. When available, the following metrics for the agreement of WTW measurements between pairs of devices were included: mean difference ± standard deviation, 95% limits of agreement (LoA), LoA width, 95% confidence interval (95 CI%), and intraclass correlation coefficient (ICC).</p><p><strong>Results: </strong>Forty-one studies, covering comparisons for 19 devices, were included. Altogether, 81 paired comparisons were performed for 4,595 eyes of 4,002 individuals. The mean difference in WTW measurements between devices ranged from 0.01 mm up to 0.96 mm, with varying CI. The 95% LoA width ranged from 0.31 to 2.45 mm (median: 0.65 mm). The majority of pairwise comparisons reported LoA wider than 0.5 mm, a clinically significant value for phakic intraocular lens sizing.</p><p><strong>Conclusions: </strong>Nearly all analyzed studies demonstrated the lack of interchangeability of the WTW parameter. The corneal diameter, assessed by means of grayscale en-face image analysis, tended to demonstrate the lowest agreement among devices compared to other measured biometric parameters. <b>[<i>J Refract Surg</i>. 2024;40(3):e182-e194.]</b>.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"40 3","pages":"e182-e194"},"PeriodicalIF":2.9,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140101815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}