Journal of Postgraduate Medicine最新文献

Skull-base temporal encephalocele: Hidden cause of temporal lobe epilepsy. 颅底颞叶脑瘤：颞叶癫痫的隐藏病因。

IF 1.6 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-04-01 Epub Date: 2023-08-04 DOI: 10.4103/jpgm.jpgm_354_22

R Pillai, A Chheda, S Agrawal, S Ravat, S Sankhe, D Muzumdar

引用次数: 0

Ambulatory blood pressure monitoring in pheochromocytoma - paraganglioma: A single center experience. 嗜铬细胞瘤-副神经节瘤的动态血压监测：单中心经验。

IF 1.6 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-04-01 Epub Date: 2023-08-04 DOI: 10.4103/jpgm.jpgm_208_23

S S Memon, P Srivastava, M Karlekar, H Thakkar, T Bandgar

{"title":"Ambulatory blood pressure monitoring in pheochromocytoma - paraganglioma: A single center experience.","authors":"S S Memon, P Srivastava, M Karlekar, H Thakkar, T Bandgar","doi":"10.4103/jpgm.jpgm_208_23","DOIUrl":"10.4103/jpgm.jpgm_208_23","url":null,"abstract":"Context/aims: Pheochromocytoma and paraganglioma (PPGL) are rare tumors, and data on ambulatory blood pressure monitoring (ABPM) in these patients and the effect of blocking on ABPM parameters is limited. We aimed to describe ABPM parameters in a cohort of PPGL at our center in western India.Methods: Retrospective study of patients with PPGL whose ABPM data was available. Demographic details, secretory status, and ABPM data were retrieved. Coefficient of variability (CV) was calculated as standard deviation/mean in percentage.Results: In the 39 included patients, mean age at presentation was 39.3 ± 14.2 yr; 20 (51.3%) were males, 25 (64.1%) hypertensive, and mean tumor diameter was 5.3 cm. In 18 patients whose baseline ABPM was done without medications, those with nocturnal blood pressure dipping (6/18, 33%) had higher serum metanephrines (median 313.2 vs. 34.7 pg/ml, P = 0.028). Despite normal office blood pressure (BP), 8.9% of systolic BP readings were >140 mmHg, and 1.2% were >160 mmHg. Among 29 patients with both pre and post-block ABPM, mean BP (systolic 121.6 vs. 132.5 mmHg, P = 0.014; diastolic 68.9 vs. 76.4 mmHg, P = 0.005) and percentage of BP readings above 140 mmHg (median 9.4% vs. 24.4%, P = 0.016) were significantly lowered after the preoperative blockade in hypertensive ( n = 19) patients, whereas CV was similar. The post-blockade ABPM characteristics were similar in patients blocked with amlodipine or prazosin.Conclusion: ABPM provides additional information about BP characteristics in PPGL. The preoperative blocking decreases the magnitude of BP excursions but does not affect BP variability.","PeriodicalId":16860,"journal":{"name":"Journal of Postgraduate Medicine","volume":" ","pages":"84-90"},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9966274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary colonic natural-killer T-cell lymphoma mimicking Crohn's disease. 模仿克罗恩病的原发性结肠天然杀伤 T 细胞淋巴瘤。

IF 1 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-04-01 Epub Date: 2022-12-19 DOI: 10.4103/jpgm.jpgm_409_22

J W Chou, Y H Wu, P J Huang

引用次数: 0

Trends in oral anticoagulant use - A 10-year retrospective analysis from a general medicine department of a tertiary care hospital in south India. 口服抗凝剂的使用趋势--来自印度南部一家三级医院普通内科的 10 年回顾性分析。

IF 1.6 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-04-01 Epub Date: 2023-07-19 DOI: 10.4103/jpgm.jpgm_10_23

V V Thomas, A Lenin, T K George, M Thenmozhi, R Iyadurai, T D Sudarsanam

{"title":"Trends in oral anticoagulant use - A 10-year retrospective analysis from a general medicine department of a tertiary care hospital in south India.","authors":"V V Thomas, A Lenin, T K George, M Thenmozhi, R Iyadurai, T D Sudarsanam","doi":"10.4103/jpgm.jpgm_10_23","DOIUrl":"10.4103/jpgm.jpgm_10_23","url":null,"abstract":"Background: The prescribing practice of newer oral anticoagulants (NOACs) has not been adequately studied in the Indian scenario.Aims: We aimed to describe the prescribing practices of oral anticoagulants, the patient profile and medical comorbidities among patients admitted in a general medicine unit.Methods: In this retrospective study of the 2742 patients prescribed vitamin- K antagonists (VKAs), during the study period, 150 cases were randomly taken for analysis to match the 105 NOACs cases. Their demographic details, clinical characteristics and treatment details were analyzed.Results: More than 95% of anticoagulants prescribed were VKAs. The prescription of anticoagulants was more common in men (median age 63 years) for prescription of NOACs and 52 years for VKAs. Dabigatran (60.9%) and warfarin (81.3%) were the most prescribed drugs in their respective classes. The most common indication was for cardiovascular diseases with atrial fibrillation (32%). Diabetes and hypertension were the most common comorbidities in patients prescribed oral anticoagulants with a larger proportion of patients with heart failure being prescribed VKAs ( P < 0.01). Patients in the NOACs group had a higher HAS-BLED high-risk score (33.3% vs. 17.3%; P = 0.002). Logistic regression analysis revealed that patients with co-morbidities of congestive heart failure were more likely to be prescribed VKAs while diabetics were more likely to receive NOACs.Conclusions: VKAs were the most prescribed anticoagulants; congestive heart failure, diabetes, and hypertension were the commonest comorbidities; and atrial fibrillation was the commonest indication. Patients with a high HAS-BLED score were prescribed NOACs more often.","PeriodicalId":16860,"journal":{"name":"Journal of Postgraduate Medicine","volume":" ","pages":"77-83"},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11160985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9835199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical considerations in congenital nontumorous obstructive hydrocephalus 先天性非肿瘤性梗阻性脑积水的手术注意事项

IF 1.6 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-01-04 DOI: 10.4103/jpgm.jpgm_780_23

D. Muzumdar

引用次数: 0

Impact of COVID-19 pandemic on healthcare delivery for lysosomal storage disorders at a tertiary care public hospital in Mumbai COVID-19 大流行对孟买一家公立三级医院溶酶体储积症医疗服务的影响

IF 1.6 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-01-04 DOI: 10.4103/jpgm.jpgm_705_23

M. Muranjan, S. Karande, S. Rajoria

{"title":"Impact of COVID-19 pandemic on healthcare delivery for lysosomal storage disorders at a tertiary care public hospital in Mumbai","authors":"M. Muranjan, S. Karande, S. Rajoria","doi":"10.4103/jpgm.jpgm_705_23","DOIUrl":"https://doi.org/10.4103/jpgm.jpgm_705_23","url":null,"abstract":"\u0000 \u0000 \u0000 Management of lysosomal storage disorders (LSDs) requires periodic visits for medical surveillance and hospitalizations. Management of LSDs may have been adversely impacted during the COVID-19 pandemic.\u0000 \u0000 \u0000 \u0000 To identify the factors impacting health care for patients with LSDs during the COVID-19 pandemic.\u0000 \u0000 \u0000 \u0000 An observational study was conducted in Mumbai comparing infusion practices and reasons for missed infusions for 15 months before March 2020 versus two phases during the pandemic (April 2020–March 2021 and April 2021–March 2022) in patients receiving intravenous enzyme replacement therapy (ERT) and on oral substrate reduction therapy (SRT).\u0000 \u0000 \u0000 \u0000 Fifteen patients with LSDs were enrolled. Before the pandemic, 6/13 (46%) were receiving ERT at the study site, 4/13 (31%) at a local hospital, and 3/13 (23%) at home; two were on SRT. The median distance traveled for receiving ERT was 37 km, and 4.4 infusions/patient were missed. From April 2020 to March 2021, two more patients opted for home ERT infusions. The median distance traveled for receiving ERT was 37 km, and 11.6 infusions/patient were missed. From April 2021 to March 2022, one more patient opted for home ERT infusions. The median distance traveled for receiving ERT was 7 km, and 5.6 infusions/patient were missed. The pandemic also affected SRT compliance adversely. For all patients, the cause of disrupted treatment was travel curbs (69%) and fear of getting COVID-19 infection (38%).\u0000 \u0000 \u0000 \u0000 Treatment of LSDs was disrupted during the pandemic, with an increase in missed ERT infusions and SRT doses.\u0000","PeriodicalId":16860,"journal":{"name":"Journal of Postgraduate Medicine","volume":"58 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139385791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary diffuse leptomeningeal primitive neuroectodermal tumor presenting as chronic meningitis. 表现为慢性脑膜炎的原发性弥漫性脑膜原始神经外胚层肿瘤。

IF 1.6 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-01-01 DOI: 10.4103/jpgm.jpgm_495_22

K G Koshy, G B Kulkarni, B N Nandeesh, A V Taalapalli

引用次数: 0

SOFT syndrome with kohlschutter-Tonz syndrome. SOFT综合征与Kohlschutter-Tonz综合征。

IF 1.6 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-01-01 DOI: 10.4103/jpgm.jpgm_1001_22

S A Mondkar, V Khadilkar, P Kasegaonkar, A Khadilkar

引用次数: 0

Lemierre syndrome complicated by bronchopleural fistula. 勒米尔综合征并发支气管胸膜瘘。

IF 1.6 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-01-01 DOI: 10.4103/jpgm.jpgm_722_22

N Kodaka, C Nakano, T Oshio, H Matsuse

引用次数: 0

Study of placental histopathology in COVID-19 mothers at a dedicated COVID-19 hospital in India. 印度一家 COVID-19 专科医院对 COVID-19 母亲胎盘组织病理学的研究。

IF 1 4区医学

Journal of Postgraduate Medicine Pub Date : 2024-01-01 DOI: 10.4103/jpgm.jpgm_60_23

S K Lad, K D Jashnani, M Pophalkar, B Jnanananda, N Mahajan

{"title":"Study of placental histopathology in COVID-19 mothers at a dedicated COVID-19 hospital in India.","authors":"S K Lad, K D Jashnani, M Pophalkar, B Jnanananda, N Mahajan","doi":"10.4103/jpgm.jpgm_60_23","DOIUrl":"10.4103/jpgm.jpgm_60_23","url":null,"abstract":"Introduction: Maternal infections can affect the placenta, which acts as a fetomaternal barrier. This study aimed to determine the spectrum of morphologic alterations in the placentas of pregnancies complicated by SARS-CoV-2 infection and the impact on fetal or neonatal outcomes.Materials and methods: This is a prospective case-control study. One hundred SARS-CoV-2 positive pregnant women and an equal number of SARS CoV-2 negative pregnant women in their third trimester who delivered at our tertiary care center between December 2020 and November 2021 were enrolled in the study. This study was conducted at the end of the first wave and during the second COVID-19 wave. Histopathological examination of the placentas was done using Amsterdam consensus criteria. We observed for evidence of maternal vascular malperfusion [MVM], fetal vascular malperfusion, and inflammation in the placenta.Results: The clinical findings were compared between the cases and controls. Evidence of MVM was seen in comparable numbers between the cases and controls, but as it involved less than 30% of the placental disc, it was considered an insignificant finding. Deciduitis was seen in equal proportions in both groups. The comparison between the asymptomatic and symptomatic groups failed to show any difference in placental pathology between both groups. There was no adverse fetal outcome seen in the pregnancies complicated by SARS-CoV-2 infection.Conclusion: Placental injury at the microscopic level was observed but was neither significant nor specific to the SARS-CoV-2 infection. SARS CoV-2 infection did not influence the placental pathology. Also, no adverse neonatal outcomes were observed.","PeriodicalId":16860,"journal":{"name":"Journal of Postgraduate Medicine","volume":" ","pages":"15-22"},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10947734/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10169932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0