European Journal of Organic Chemistry最新文献_第10页

Latent Ruthenium Complexes Supported by Two N‐Heterocyclic Carbene Ligands: Synthesis and Catalytic Activity with Distinctive Activation 两个N -杂环卡宾（NHC）配体支持的潜在钌配合物的合成及其独特活化的催化活性

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-24 DOI: 10.1002/ejoc.202500284

Anna Vaisman , Hosein Tafazolian , Diana Stoianova , Jonathan M. Goldberg , Kristina Goulinian , Angelino Doppiu , Adam M. Johns , Norberto Gabriel Lemcoff

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引用次数: 0

Total Syntheses of the Linearly‐Fused Prenylated Indole Alkaloids Asperversiamides H and M via Oxidative Rearrangement of the Putative Biosynthetic Precursor Dihydrocarneamide A 通过推测的生物合成前体二氢烷酰胺A的氧化重排，全合成线性融合的烯酰化吲哚类生物碱- Asperversiamides H和M

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-24 DOI: 10.1002/ejoc.202500277

Xinru Li , Zhongnan Xu , Shenting Zhang , Wenzhu Yu , Shen Tan , Martin G. Banwell

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引用次数: 0

Mechanistic Insights into the [3+2] Cycloaddition Reaction of Azomethine Ylides with Methyl Vinyl Ketone in the Triplet Excited State: A Molecular Electron Density Theory Study 三态激发态下亚甲酰亚胺与甲基乙烯酮[3+2]环加成反应的机理：分子电子密度理论研究

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-24 DOI: 10.1002/ejoc.202500241

Luis R. Domingo , Patricia Pérez , Assem Barakat

{"title":"Mechanistic Insights into the [3+2] Cycloaddition Reaction of Azomethine Ylides with Methyl Vinyl Ketone in the Triplet Excited State: A Molecular Electron Density Theory Study","authors":"Luis R. Domingo , Patricia Pérez , Assem Barakat","doi":"10.1002/ejoc.202500241","DOIUrl":"10.1002/ejoc.202500241","url":null,"abstract":"<div><div>The [3+2] cycloaddition (32CA) reaction of an azomethine ylide with methyl vinyl ketone in the ground and first triplet excited states has been studied within the framework of molecular electron density theory. A density functional theory‐based reactivity analysis indicates that, while azomethine ylide behaves as a supernucleophile in both states, vinyl ketone acts as a strong electrophile. This 32CA reaction presents a very low activation energy both in the ground state, 3.40 kcal mol<sup>−1</sup>, and in the triplet state, 1.47 kcal mol<sup>−1</sup>, in the gas phase. While in the ground state, the 32CA reaction is entirely <em>ortho</em> regio and fully <em>endo</em> stereoselective, in the triplet state it is entirely <em>ortho</em> regioselective but only partially <em>endo</em> stereoselective. In the ground state, the reaction proceeds to form the spirooxindole after passing through the transition state structure, whereas in the triplet state, the reaction stops at a biradical intermediate, which requires an intersystem crossing to yield the final spirooxindole. Analysis of the kinetic parameters of the 32CA reaction in the two states in methanol indicates that in the triplet state, the reaction is only 589 times faster than in the ground state.</div></div>","PeriodicalId":167,"journal":{"name":"European Journal of Organic Chemistry","volume":"28 24","pages":"Article e202500241"},"PeriodicalIF":2.5,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143946208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of Rhamnose‐Modified Lewis‐X‐Containing Saponins 鼠李糖修饰Lewis - X -含皂苷的合成

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-24 DOI: 10.1002/ejoc.202500285

Oscar Javier Gamboa Marin , Nitish Verma , Maude Cloutier , Charles Gauthier

引用次数: 0

Terpenes and Terpenoids: How can we use them? 萜烯和萜类：我们如何使用它们？

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-24 DOI: 10.1002/ejoc.202401151

Jay Hanssens , Diego Meneses , Jordy M. Saya , Romano V. A. Orru

{"title":"Terpenes and Terpenoids: How can we use them?","authors":"Jay Hanssens , Diego Meneses , Jordy M. Saya , Romano V. A. Orru","doi":"10.1002/ejoc.202401151","DOIUrl":"10.1002/ejoc.202401151","url":null,"abstract":"<div><div>As one of the twelve fundamental principles of green chemistry, the employed feedstocks in chemical processes received substantial attention over the past decades. These efforts can be attributed to Werpy's 2004 list of top‐value‐added chemicals from biomass. Conventional fossil‐based feedstocks are both depleting and environmentally damaging, leading to the transition towards renewable, bio‐based platform chemicals. Terpenes and terpenoids are a group of bio‐based compounds well known throughout the scientific community. Although their acquirement from natural feedstocks is well known, comprehensive overviews of their applications in synthetic chemistry remain limited. Herein, a full comprehensive overview of the reported chemistry with terpenes is provided, while specifically highlighting their reactivity. Fifteen of the most common and useful monoterpenes and terpenoids are discussed, followed by a list of the remaining known compounds belonging to this group. These fifteen compounds have been employed in a vast number of chemical transformations with different applications including: polymerizations, total syntheses, chiral reagents/auxiliaries, pharmaceuticals, and chemical conversion to other useful bio‐based chemicals. The presented chemistry in this work aims to provide chemists with a useful tool that should facilitate and stimulate the search for more sustainable, renewable, and environmentally friendly starting points for novel synthesis routes.</div></div>","PeriodicalId":167,"journal":{"name":"European Journal of Organic Chemistry","volume":"28 24","pages":"Article e202401151"},"PeriodicalIF":2.5,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143723312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Total Synthesis of Pegaharmine I Enabled by Visible‐Light Photocatalytic Nitrone Formation 可见光催化形成硝酮的聚甲沙明I的全合成

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-24 DOI: 10.1002/ejoc.202500245

Manikanta Swami Pothana , Huang‐Chieh Lu , Bor‐Cherng Hong , Su‐Ying Chien

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Front Cover: Recent Advances in Transition Metal-Free Strategies for the Transformation of Amides into Carbonyl Compounds (Eur. J. Org. Chem. 23/2025) 封面：酰胺转化为羰基化合物的过渡无金属策略的最新进展。j . Org。化学23/2025)

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-24 DOI: 10.1002/ejoc.202582301

Karthik Rajan Rajamanickam, Robin Prakash Sirvin Rajan, Nithin Pootheri, Chin-Fa Lee, Sunwoo Lee

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Introduction of Structural Diversity at the C2 Position of Unsaturated Iminosugars through Palladium‐Catalysed Cross‐Coupling Reactions 钯催化交叉偶联反应引入不饱和亚糖C2位结构多样性

IF 2.8 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-23 DOI: 10.1002/ejoc.202500502

Yves Bleriot, angelique ferry, quentin joachim, delphine carry, mattéo di pasquale, jerome marrot, jacques uziel, nadege lubin-germain, Jerome desire, atsushi kato, suzuka yamamoto

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Rhodium(II)‐Catalyzed Oxo‐Amination of Aryl Cyclopropanes 铑（II）催化芳基环丙烷氧胺化反应

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-23 DOI: 10.1002/ejoc.202500235

Zhiying Fan , Nengde Liang , Yuanhua Wang

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Visible Light‐Driven Multicomponent Reactions for the Synthesis of Diverse Heterocyclic Frameworks 可见光驱动多组分反应合成各种杂环骨架

IF 2.5 3区化学

European Journal of Organic Chemistry Pub Date : 2025-06-23 DOI: 10.1002/ejoc.202500216

Narsimhaswamy Dubasi , Ravi Varala , Murali Mohan Achari Kamsali , Mohammed Mujahid Alam

引用次数: 0