Hakeam A. Hakeam, Khadija A. Sarkhi, Alla Iansavichene
{"title":"Tigecycline and Hypoglycemia, When and How?","authors":"Hakeam A. Hakeam, Khadija A. Sarkhi, Alla Iansavichene","doi":"10.1177/87551225231211737","DOIUrl":"https://doi.org/10.1177/87551225231211737","url":null,"abstract":"Objective: To describe the clinical characteristics of hypoglycemia that develop with tigecycline therapy and to review and summarize the current evidence of this uncommonly occurring metabolic adverse effect of tigecycline therapy. Underlying risk factors and potential mechanisms are also discussed. Data source: A 3-phase literature search was performed. In phase 1, the Cochrane Central Register of Controlled Trials (CENTRAL) Library, MEDLINE, and Embase electronic databases were searched for hypoglycemia and tigecycline, published from inception until August 2023. In phase 2, MEDLINE was searched for tigecycline randomized controlled trials and results were manually screened for hypoglycemia. In phase 3, the US Food and Drug Administration Adverse Event Reporting System public dashboard was searched for reports on tigecycline and hypoglycemia from June 2005 until July 2023. Study selection and data extraction: Relevant English-language citations and those conducted in humans were considered. Relevance to patient care and clinical practice: Hypoglycemia of various causes is an independent mortality risk. This review raises awareness among clinicians about the possibility of hypoglycemia with tigecycline therapy. Conclusion: Data on tigecycline-related hypoglycemia are scarce. Hypoglycemia may occur at any time during tigecycline therapy and can be severe and persist for days after tigecycline cessation. Renal dysfunction or renal replacement therapy may predispose to severe hypoglycemia during tigecycline therapy. Tigecycline-related hypoglycemia may develop in patients with or without diabetes mellitus and appears independent of insulin or antidiabetic agents. Intravenous dextrose showed efficacy in the restoration of euglycemia. Studies are needed to determine whether tigecycline-related hypoglycemia is iatrogenic or spontaneous.","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"15 3","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139261601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica H. Williams, Savannah Young, Kaitlyn Wallace, E. Weeda
{"title":"Annual Wholesale Acquisition Costs of Novel Drugs Relative to US County-Level House Prices","authors":"Jessica H. Williams, Savannah Young, Kaitlyn Wallace, E. Weeda","doi":"10.1177/87551225231213259","DOIUrl":"https://doi.org/10.1177/87551225231213259","url":null,"abstract":"","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"23 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139273642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huy Pham, Tricia Gangoo-Dookhan, Genevieve Hale, Alexandra Perez, Tina Joseph
{"title":"Impact of Student Pharmacist-Led Transition-of-Care Services on 30-Day Hospital Readmissions at a University Call Center.","authors":"Huy Pham, Tricia Gangoo-Dookhan, Genevieve Hale, Alexandra Perez, Tina Joseph","doi":"10.1177/87551225231187832","DOIUrl":"10.1177/87551225231187832","url":null,"abstract":"<p><p><b>Background:</b> Transition of care (TOC) refers to the movement of patients between different health care settings due to changes in medical conditions and needs. Pharmacists can play an important role in TOC services as polypharmacy is a common reason for hospital readmission that costs the US taxpayers an average of $17 billion annually. <b>Objective:</b> The purpose of this study is to evaluate the impact of TOC telehealth services provided by pharmacy students at a university-based call center on 30-day hospital readmission. <b>Methods:</b> In this retrospective observational study, an electronic chart review was conducted for patients who were discharged from the hospital and received a telephone call from pharmacy students. Patients were referred to the pharmacy team from a primary care provider office. The co-primary endpoints were the number of 30-day all-cause hospital readmissions (including emergency department visits) and 30-day readmission due to initial admission diagnosis in patients who received a telephonic TOC call from a pharmacy student compared with patients who declined or were unable to be reached. Types of pharmacy-related TOC interventions provided by students were also collected. <b>Results:</b> A total of 84 patients were included in this study. All-cause 30-day readmission was similar between groups (13% vs 15.8%), whereas 30-day readmission due to initial admission diagnosis was much lower in the intervention group (5.9% vs 11.1%). Although a positive trend was observed in favor of the intervention group, a statistically significant difference was not observed for both 30-day all-cause readmission and 30-day readmission due to initial admission diagnosis. Medication reconciliation, adherence counseling, and lifestyle education (diet, exercise) are the most common topics discussed with the patients during TOC interventions. <b>Conclusion:</b> Using student pharmacists to provide postdischarge TOC calls can be a benefit to the patient and the health care team while offering pharmacy students valuable learning experience prior to graduation.</p>","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"39 5","pages":"207-211"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41122896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wernicke's Encephalopathy and Serotonin Syndrome: A Case Report of Overlapping Pathologies.","authors":"Justin P Reinert, Paul Brady","doi":"10.1177/87551225231195536","DOIUrl":"10.1177/87551225231195536","url":null,"abstract":"<p><p><b>Objective:</b> Acute encephalopathy is a common symptom encountered in critically ill patients and may be associated with Wernicke's encephalopathy (WE) or serotonin syndrome (SS). We describe a patient who presented with clinical manifestations of both WE and SS and who responded to treatment for both pathologies. <b>Case:</b> A 56-year-old male presented after being found unresponsive and in a questionable tonic-clonic state. Past medical history was significant for depression managed with fluoxetine 20 mg by mouth daily and alcohol use disorder. A physical exam revealed severe clonus in the bilateral lower extremities; diffuse hyperreflexia along with akinesia on the left upper extremity; ophthalmoplegia; and persistent tachycardia despite pharmacologic interventions. It was learned that the patient had been taking his fluoxetine 3 times per day rather than daily as prescribed. Oral cyproheptadine was administered at a 12 mg initial dose followed by 4 mg every 6 hours. A thiamine regimen of 500 mg intravenous (IV) every 8 hours in addition to folic acid 1 mg IV every 24 hours was initiated to treat WE. Physical symptoms of both WE and SS resolved within 48 hours, and the patient was ultimately discharged to home in stable condition. <b>Discussion/Conclusions:</b> The clinical diagnosis of both WE and SS in this case is supported by the Caine and Hunter criteria, respectively, as well as the resolution of symptoms with accepted treatment modalities for each. It is important for clinicians to be cognizant of potential overlapping pathologies when patients present with nonspecific symptoms, especially acute encephalopathy, in the intensive care unit.</p>","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"39 5","pages":"237-240"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515966/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41141856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shannon M Carabetta, Bryan Allen, Chad Cannon, Kirubel Hailu, Totty Johnson
{"title":"Atracurium Versus Cisatracurium in the Treatment of Acute Respiratory Distress Syndrome.","authors":"Shannon M Carabetta, Bryan Allen, Chad Cannon, Kirubel Hailu, Totty Johnson","doi":"10.1177/87551225231194031","DOIUrl":"10.1177/87551225231194031","url":null,"abstract":"<p><p><b>Background:</b> Neuromuscular blocking agents are one of the few medication classes that have demonstrated a clinical benefit in patients with severe acute respiratory distress syndrome (ARDS). However, most literature utilized cisatracurium, and utilization of atracurium is limited to 1 small study. <b>Objective:</b> The purpose of this study was to provide further evidence comparing the safety and efficacy of atracurium versus cisatracurium for the treatment of ARDS. <b>Methods:</b> This multicenter, retrospective, observational cohort noninferiority study was conducted at 3 hospitals within a tertiary health care system. We included subjects diagnosed with ARDS who received either atracurium or cisatracurium for at least 12 hours. The primary outcome measured the change in PaO<sub>2</sub>/FiO<sub>2</sub> (P/F) ratio from baseline to 48 hours after initiation. <b>Results:</b> Baseline characteristics were similar between groups except for a higher median age and a higher proportion of subjects who were COVID-positive in the atracurium group. There were also some noted differences in the baseline P/F ratios. In a multivariable model adjusting for baseline characteristics, the change in the P/F ratio for atracurium was noninferior to cisatracurium at 24, 48, and 72 hours. A significant cost reduction, measured as cost per patient per day, was seen with the use of atracurium ($14.81-$25.16 vs $33.86-$41.91). <b>Conclusion:</b> Atracurium appears to be a safe and cheaper alternative agent in the management of ARDS.</p>","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"39 5","pages":"212-217"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41133862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Surafel G Mulugeta, Nancy C MacDonald, Caren J El-Khoury, Susan L Davis, Rachel M Kenney
{"title":"Impact of a Standardized, Pharmacist-Initiated \"Test-Claim\" Workflow for Anticipating Barriers to Accessing Discharge Antimicrobials.","authors":"Surafel G Mulugeta, Nancy C MacDonald, Caren J El-Khoury, Susan L Davis, Rachel M Kenney","doi":"10.1177/87551225231196047","DOIUrl":"10.1177/87551225231196047","url":null,"abstract":"<p><p><b>Background:</b> Inability to access and afford discharge oral antimicrobials may delay discharges or result in therapeutic failure. \"Test-claims\" have the potential to identify such barriers. <b>Objective:</b> This study evaluated discharge antimicrobial access and patient outcomes after implementation of a standardized, inpatient pharmacist-initiated antimicrobial discharge medication cost inquiry (aDMCI) process. <b>Methods:</b> This was an Institutional Review Board (IRB)-approved, pilot retrospective cohort study that included adults admitted for ≥72 hours from November 1, 2018, to February 28, 2019, and discharged on oral antimicrobials. Patients with a cost inquiry (aDMCI group) were compared with those without (standard-of-care, SOC, group). Primary endpoint was discharge delay. Secondary endpoints included percentage of patients discharged on suboptimal antimicrobials and medication errors from aDMCI. <b>Results:</b> 84 patients were included: 43 in SOC and 41 in aDMCI. Seventy-five antimicrobial cost inquiries were evaluated among 41 patients. There were no discharge delays or medication errors associated with the standardized \"test-claim\" (aDMCI) workflow. Patients in the SOC group had a greater Charlson Comorbidity Index (4 [2-6] vs 2 [1-4], <i>P =</i>0.004), were more likely to be immunosuppressed (24, 56% vs 12, 29%; <i>P =</i>0.014), and had longer hospitalization (8 [5-15] vs 6 [5-9] days, <i>P =</i>0.026). Primary access barriers were prior-authorization (8, 11%) and associated with linezolid and moxifloxacin cost inquiries. Most aDMCIs results were available in <24 hours (66, 88%). <b>Conclusions:</b> The aDMCI process is safe and offers an actionable transition of care tool that can identify barriers to accessing discharge medications while insulating patients from surprise out-of-pocket cost.</p>","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"39 5","pages":"218-223"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41133863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Proton Pump Inhibitor Deprescription Prospective Study in Patients Without Indication: Are There Differences in Proportion of Restarts According to Withdrawal Strategy?","authors":"Anna Barraquer Comes, Pedro Roy Millán","doi":"10.1177/87551225231195216","DOIUrl":"10.1177/87551225231195216","url":null,"abstract":"<p><p><b>Background:</b> The increasing utilization of proton pump inhibitors (PPIs) in patients without clear medical indications has raised concerns regarding potential risks, highlighting the importance of deprescription. However, comparative analyses of withdrawal strategies (abrupt vs gradual) in this context remain scarce or of low quality. <b>Aim:</b> This study aimed to evaluate the success rate of deprescribing PPIs in hospitalized patients without a documented indication and compare the proportion of treatment restarts based on withdrawal strategy. <b>Method:</b> An uncontrolled, open-label prospective observational study was conducted on patients receiving PPI treatment during hospital admission between May 2017 and July 2018. Deprescription was recommended for patients without a clear indication. Follow-up continued until discharge, with monitoring for rebound symptoms. The percentage of restarts based on the withdrawal strategy was compared using the chi-square test. <b>Results:</b> A total of 402 patients were reviewed, among whom 27% lacked a medical indication (mean age > 60 years, polymedicated), while 70% were prescribed PPIs electronically. Deprescription was performed in 49% of patients, with 64% undergoing abrupt withdrawal. Rebound symptoms led to treatment restart in 15% of cases. However, the chi-square test revealed no significant differences in restart proportions between the abrupt and gradual withdrawal groups (<i>P</i> = 0.365). <b>Conclusion:</b> Deprescribing PPIs is deemed safe, particularly for polymedicated geriatric patients, as it leads to a low percentage of restarts regardless of the chosen withdrawal strategy. However, the high percentage of PPI prescription without a clear indication underlines the need for periodic reassessment to avoid unnecessary risks and overuse.</p>","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"39 5","pages":"224-230"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41136031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rithi J Chandy, Diem-Phuong D Dao, Cristian C Rivis, Divya M Shan, Steven R Feldman
{"title":"Noncorticosteroid Topical Therapies for the Treatment of Plaque Psoriasis: A Narrative Review.","authors":"Rithi J Chandy, Diem-Phuong D Dao, Cristian C Rivis, Divya M Shan, Steven R Feldman","doi":"10.1177/87551225231193057","DOIUrl":"10.1177/87551225231193057","url":null,"abstract":"<p><p><b>Objective:</b> The objective was to compare the safety and efficacy of noncorticosteroid topical treatments for plaque psoriasis. <b>Data Sources:</b> A literature search of the PubMed database was performed (January 1978 to May 2023) using the keywords <i>plaque psoriasis</i>, <i>tapinarof, benvitimod, Vtama, roflumilast, Zoryve, pimecrolimus, tacrolimus, tazarotene, tacalcitol, calcitriol, Vectical, calcipotriene, Dovonex, tacalcitol, vitamin D analogs, salicylic acid, non-corticosteroid topical, Investigator's Global Assessment</i>, and <i>Physician's Global Assessment</i>. <b>Study Selection and Data Extraction:</b> Relevant English-language articles and clinical trial data were considered. <b>Data Synthesis:</b> Six noncorticosteroid topical classes for the treatment of plaque psoriasis were selected. The percentage of patients with plaque psoriasis who achieved Investigator's Global Assessment (IGA) success after 8 weeks of treatment with tacalcitol, calcipotriene/betamethasone dipropionate compound, tazarotene/halobetasol propionate, and roflumilast was 17.9%, 39.9%, 40.7%, and 42.4%, respectively. For 12-week trials of tapinarof and coal tar, 37.4% and 58.2% of patients achieved IGA success, respectively. There were 48% and 71.4% reductions in IGA scores with salicylic acid (12 weeks) and pimecrolimus (4 weeks), respectively. Finally, 66.7% of patients achieved Physician's Global Assessment success with 8 weeks of tacrolimus. There were no serious adverse events for the noncorticosteroid topicals. <b>Conclusion:</b> Noncorticosteroid topicals are suitable options for patients with plaque psoriasis who would like to avoid topical corticosteroids or have experienced adverse effects from chronic corticosteroid use. Due to treatment duration differences and varied outcome measures, it is unclear which noncorticosteroid topical is most efficacious; however, calcineurin inhibitors appear to exhibit the greatest efficacy. Each topical was efficacious in treating plaque psoriasis and had an adequate safety profile. Despite several treatment options for plaque psoriasis, medication adherence is a limiting factor.</p>","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"39 5","pages":"247-255"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41124344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chukwuemeka Augustine Nwachuya, Anthony Uche Umeh, Jennifer Chinaza Ogwurumba, Ifunanya Ngozi Chinedu-Eze, Chukwunenye Christopher Azubuike, AbdulMuminu Isah
{"title":"Effectiveness of Telepharmacy in Rural Communities in Africa: A Scoping Review.","authors":"Chukwuemeka Augustine Nwachuya, Anthony Uche Umeh, Jennifer Chinaza Ogwurumba, Ifunanya Ngozi Chinedu-Eze, Chukwunenye Christopher Azubuike, AbdulMuminu Isah","doi":"10.1177/87551225231190567","DOIUrl":"10.1177/87551225231190567","url":null,"abstract":"<p><p><b>Objectives:</b> This review examined the effectiveness of telepharmacy in rural communities in Africa to identify the barriers that hinder its implementation and integration as well as highlight the gaps in the existing research on telepharmacy. <b>Data Source:</b> PubMed and Google Scholar search (2008-2023) was conducted using keywords related to telepharmacy, telemedicine, telehealth, and rural communities. <b>Study Selection and Data Extraction:</b> The inclusion criteria for the review include peer-reviewed articles published in English language and studies that focus on the implementation and evaluation of telepharmacy in rural communities. <b>Data Synthesis:</b> In all articles used, access to quality health care in rural communities has been a persistent challenge in Africa. Digital technologies such as telemedicine, telepharmacy, and artificial intelligence were reported to have emerged as promising solutions to improve health care access and outcomes in rural communities. Telepharmacy, in particular, has the potential to provide medication-related services to patients irrespective of one's location. However, the implementation of telepharmacy in Africa has been slow, and there are several barriers affecting its integration and adoption in rural communities that include access to technology, limited infrastructure, and regulatory challenges. Gaps and limitations in the existing research on telepharmacy in rural communities were highlighted from the articles. <b>Conclusion:</b> Telepharmacy can improve health care access and outcomes in rural communities by bridging the gap between pharmacists and patients. However, the lack of infrastructure, inadequate funding, and regulatory challenges pose significant barriers to its implementation. Future research should focus on addressing these challenges and exploring the potential of telepharmacy to improve health care in rural communities in Africa.</p>","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"39 5","pages":"241-246"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41118908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riley J Larson, Ann M Philbrick, Caroline S Carlin, Ila M Harris
{"title":"Evaluating the Clinical Effect of Personal Continuous Glucose Monitoring in a Diverse Population With Type 2 Diabetes.","authors":"Riley J Larson, Ann M Philbrick, Caroline S Carlin, Ila M Harris","doi":"10.1177/87551225231194027","DOIUrl":"10.1177/87551225231194027","url":null,"abstract":"<p><p><b>Objective:</b> To determine the clinical effect of personal continuous glucose monitoring (CGM) in a diverse population with type 2 diabetes (T2D). <b>Research Design and Methods:</b> A report was created from the electronic health record identifying adults prescribed CGM at an urban family medicine clinic between January 1, 2019, and February 23, 2022. An \"index date\" was identified as the start of CGM. The closest hemoglobin A<sub>1c</sub> (A1c) 6 months or more after the index date was identified as the \"follow-up date.\" The primary outcome of this study was to compare the percentage of individuals meeting the MN Community Measure (MNCM) D5 HbA1c goal of <8% at the follow-up date versus the index date. <b>Results:</b> Seventy-two patients were identified after the exclusion criteria were applied. Approximately one-third of patients required utilization of an interpreter and 76% of patients were of a racial or ethnic minority. The mean HbA1c prior to CGM use was 9.8%, with 16.7% of the population meeting the MNCM D5 A1c goal of <8%. At the follow-up date, the mean A1c was 8.4% (mean difference -1.4%; <i>p</i> < 0.001), with 41.7% of the population meeting goal (mean difference +25%; <i>p</i> < 0.001). Subgroup analyses affirm that the results of the primary outcome were sustained despite insulin use status. <b>Conclusion:</b> A diverse population with T2D had a significant reduction in A1c and was more likely to meet the MNCM D5 A1c goal of <8% after an average of 6 months using personal CGM.</p>","PeriodicalId":16796,"journal":{"name":"Journal of Pharmacy Technology","volume":"39 5","pages":"231-236"},"PeriodicalIF":1.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41136029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}