Journal of Pharmacy Practice and Research最新文献

{"title":"Hospital-initiated post-discharge medication reviews in Australia: expert opinion on the barriers and enablers to implementation","authors":"Manya Angley BPharm, PhD, AACPA, AdvPracPharm, FSHP, FPS,&nbsp;Deirdre Criddle BPharm, GradDipPharm, AACPA, AdvPracPharm, FPS, MSHP, MRPharmS,&nbsp;Deborah Rigby BPharm, GradDipClinPharm, AdvPracPharm, AACPA, FPS, FSHPA, FACP, FASCP, FAICD,&nbsp;Rohan A. Elliott BPharm, BPharmSc (Hons), MClinPharm, FSHP, PhD,&nbsp;Katie Phillips BPharm (Hons), Grad Cert Pharmacy Practice, AACPA, MSHP,&nbsp;Jonathan Penm BPharm (Hons), PhD, GradCert (Higher Ed), FFIP, FSHP, FHEA,&nbsp;Janet K. Sluggett BPharm (Hons), PhD, GradDipClinEpid, AACPA, FSHP, GAICD,&nbsp;Joy Gailer BPharm, DipHospPharm, BCPS, AdvPracPharm, FPS, MSHP,&nbsp;Horst Thiele DipPharm, MSHP,&nbsp;Amy T. Page PhD, BHealth Sci, BPharm, Grad Dip Biostatistics, Grad Cert Health Prof Ed, Grad Cert Pharm Pract, MClinPharm, AACPA, AdvPracPharm, FPS,&nbsp;Carly Pauw BPharm, MSHP,&nbsp;Sarah Gillespie BPharm, AACPA, MSHP, MPS,&nbsp;Sepehr Shakib MBBS, PhD, FRACP,&nbsp;Jerry Yik BPharm MPubPol","doi":"10.1002/jppr.1832","DOIUrl":"10.1002/jppr.1832","url":null,"abstract":"<p>Medication-related harm can occur during transitions of care. Revised Home Medicines Review (HMR) and Residential Medication Management Review (RMMR) program rules were published in April 2020 which allowed provision for some hospital medical practitioners to refer at-risk patients for medication review. In turn, the Society of Hospital Pharmacists of Australia's (SHPA's) Transitions of Care and Primary Care Leadership Committee developed a framework to support hospitals facilitating Hospital-Initiated Medication Reviews (HIMRs) via three pathways: HMR, RMMR, and Hospital Outreach Medication Review. Following the compilation of draft barriers and enablers to implementation of the SHPA HIMR framework, refinement occurred after broad consultation with hospital- and primary care-based pharmacists with transitions of care experience. The finalised list of barriers and enablers can inform broadscale implementation of the SHPA HIMR framework to reduce medication-related harm when high-risk patients transition from hospital to primary care and aged care.</p>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 6","pages":"446-453"},"PeriodicalIF":2.1,"publicationDate":"2022-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44798004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing chronic obstructive pulmonary disease in primary care: clinical characteristics of patients receiving inhaled corticosteroids","authors":"Madisyn Strain PharmD, BCPS, BCACP,&nbsp;Kaci Boehmer PharmD, BCACP, CDCES,&nbsp;Justin Usery PharmD, BCPS","doi":"10.1002/jppr.1835","DOIUrl":"10.1002/jppr.1835","url":null,"abstract":"Inhaled corticosteroid (ICS) therapy in patients with chronic obstructive pulmonary disease (COPD) has been associated with a variety of unfavourable effects, including increased risk of pneumonia, and is only recommended if specific characteristics are present to ensure patients derive the most benefit.","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 6","pages":"438-445"},"PeriodicalIF":2.1,"publicationDate":"2022-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42289094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative medication management for older people","authors":"Samuel Johnson MBBS,&nbsp;Cilla Haywood MBBS, PhD, FRACP","doi":"10.1002/jppr.1834","DOIUrl":"10.1002/jppr.1834","url":null,"abstract":"<p>The average age of surgical candidates is increasing with the ageing population worldwide. Major surgery in older patients is associated with a significant risk of complications due to physiologic changes occurring with ageing and individual patient factors such as frailty, polypharmacy, and multimorbidity. Periodic medication review should be part of the routine management of all older patients, with the perioperative period presenting an opportune time for this review. Regular medications may need short-term modification during the surgical period. Medications implicated in increasing risk of inducing or worsening delirium should be identified and withdrawal considered ahead of time. Perioperative commencement of medication aimed at reducing risk of other complications, including cardiovascular events, should be considered on an individual basis, analysing risks and benefits. Comprehensive medication review and careful planning through the perioperative period may enhance the prospects of recovery and reduce morbidity and mortality for older surgical patients.</p>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 5","pages":"391-401"},"PeriodicalIF":2.1,"publicationDate":"2022-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1834","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45302932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response from Authors: a benchmarking scoping review of research output from hospital pharmacy departments in Australia","authors":"Jonathan Penm BPharm (Hons), PhD, GradCert (Higher Ed),&nbsp;Sujita Narayan PhD,&nbsp;Jan-Willem Alffenaar PharmD, PhD,&nbsp;Jacinta L. Johnson BPharm (Hons), PhD, AdvPracPharm,&nbsp;Sanja Mirkov BPharm, PGDipPH,&nbsp;Amy T. Page PhD, MClinPharm, GradDipBiostat, GCertHProfEd, MAACP, GStat, FPS, AdvPracPharm,&nbsp;Lisa G. Pont BSc, BPharm, MSc(Epi), PhD,&nbsp;Asad E. Patanwala PharmD, MPH","doi":"10.1002/jppr.1833","DOIUrl":"10.1002/jppr.1833","url":null,"abstract":"<p>To the Editor,</p><p>We thank Elliott et al.<span>¹</span> and Misko et al.<span>²</span> for their feedback on our recent scoping review.<span>³</span> They both provided valuable feedback for future benchmarking studies. We acknowledge that these limitations may impact state or territory-based benchmarking but reinforce that the national benchmarking offered by our paper appears useful for such sites to compare against.</p><p>Amy Page is an Editorial Board member of the <i>Journal of Pharmacy Practice and Research</i> and a co-author of this article. To minimise bias, she was excluded from all editorial decision-making related to the acceptance of this article for publication.</p><p>All listed authors comply with the <i>Journal's</i> authorship policy.</p><p>No ethics approval was required for this letter to the editor.</p>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 5","pages":"406-407"},"PeriodicalIF":2.1,"publicationDate":"2022-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1833","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48711928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving medicine information on discharge summaries through implementation of a reconciliation-based intervention","authors":"Anna Nguyen BPharm (Hons), GradCertPharmPrac,&nbsp;Stephanie Gibson BPharm (Hons), MClinPharm,&nbsp;Paul Wembridge BPharm (Hons), MClinPharm","doi":"10.1002/jppr.1828","DOIUrl":"10.1002/jppr.1828","url":null,"abstract":"<p>The handover of medication-related information at the point of discharge often occurs via the discharge summary (DS), although these frequently contain errors. We aimed to investigate whether an intern pharmacist reviewing the medication details in discharge summaries (DSs), reconciling them with the discharge prescription and pointing out any discrepancies with the medical staff would reduce the rate of medication errors. The intervention was retrospectively reviewed by comparing medication information on the DS with the discharge prescription (considered the ‘source of truth’). Error rates on the DS were compared to a control group of patients discharged over a different 2-week period from the same ward. A modified APINCH (Antimicrobials, Potassium and other electrolytes, Insulin, Narcotics and other sedatives, Chemotherapeutic agents, Heparin and other anticoagulants, Systems) classification system was used to identify high-risk errors. The time taken to perform the intervention was measured and details of any recommendations collected. The study included 22 intervention patients and 31 control patients. Patients who received the intervention were less likely to have one or more medication errors on their DS (any: 4% vs 84%, p &lt; 0.01; high-risk: 0% vs 29%, p &lt; 0.01). The intern pharmacist made a total of 77 recommendations during the intervention. Six recommendations (8%) related to high-risk medications. The median time required to undertake the first review was 4 min, and the second review took 1 min. In conclusion, we found a reconciliation-based intervention involving an intern pharmacist could reduce the rate of medication errors on DSs.</p>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 6","pages":"454-457"},"PeriodicalIF":2.1,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1828","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43848719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In response: A benchmarking scoping review of research output from hospital pharmacy departments in Australia","authors":"Rohan A. Elliott BPharm, BPharmSc(Hons), MClinPharm, PhD, FSHP,&nbsp;Simone E. Taylor BPharm, PharmD, GradCertClinResMeth","doi":"10.1002/jppr.1831","DOIUrl":"10.1002/jppr.1831","url":null,"abstract":"&lt;p&gt;To the Editor,&lt;/p&gt;&lt;p&gt;We read with interest the article by Penm et al.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; describing a benchmarking scoping review of research output from principal referral hospital pharmacy departments in Australia. We support the notion that benchmarking research output may assist pharmacy departments to improve their research performance, which has the potential to benefit patients, staff, and the broader health system.&lt;span&gt;&lt;sup&gt;1, 2&lt;/sup&gt;&lt;/span&gt; For this to be effective, it is important that benchmarking data be as accurate as possible and presented in a way that enables pharmacy departments to compare themselves with departments in similarly sized health services. Here we propose some ideas that may improve these aspects for future benchmarking studies.&lt;/p&gt;&lt;p&gt;A limitation of the benchmarking study noted by its authors was that the search strategy would not have captured research articles where authors used the name of their local health network instead of the principal hospital in their affiliation.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; We are concerned that this may have led to a significant under-estimation of pharmacy research output. This is especially likely in Victoria, where each of the principal referral hospitals is part of a health network with one pharmacy department operating across all hospitals in the network. For example, Austin Health has one pharmacy department across its three hospitals, including the principal referral hospital, Austin Hospital. Pharmacy staff rotate between, or work across, the three sites. Research projects often span multiple sites. The affiliation that staff usually use is ‘Pharmacy Department, Austin Health’. Over the 2018–2020 benchmarking study period, the Austin Health Pharmacy Department produced over 50 peer-reviewed research articles that would have met the review's inclusion criteria.&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;The affiliation search terms described in Appendix S1 of the benchmarking paper&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; are based on those used by the Australian Institute of Health and Welfare for principal referral hospitals, but they are not necessarily the affiliation terms used by pharmacy department–based authors. The search terms would have missed many articles from Victorian principal referral hospitals at Austin Health, Barwon Health, and Monash Health but would have captured articles from all hospitals within the Alfred, Royal Melbourne, and St Vincent's networks. Hence, the data cannot be used to accurately benchmark Victorian hospitals.&lt;/p&gt;&lt;p&gt;An approach that would ensure data are consistently captured for all principal referral hospitals is to contact each pharmacy department to verify the literature search results. Criteria for which articles are eligible from pharmacy departments that service secondary hospitals in addition to the principal hospital could be developed (e.g. the article must have been produced by one or more pharmacy department staff members who worked at the principal h","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 5","pages":"404-405"},"PeriodicalIF":2.1,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1831","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49154896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy comparisons of rituximab biosimilars to the reference product in patients with cancer: a systematic meta-analysis review","authors":"Nina K. Song BPharm (Hons),&nbsp;Hala Musa BSc (Hons), MSc, MPharm,&nbsp;Michael Soriano BS Pharmacy (PH),&nbsp;Mellissa Batger BSc, MPharm,&nbsp;Bryson Hawkins BPharm (Hons),&nbsp;Iqbal Ramzan Dip Pharmacy (NZ), MSc, PhD (USyd),&nbsp;David E. Hibbs BSc (Hons), PhD, Grad Cert Ed (Higher Ed),&nbsp;Jennifer A. Ong BPharm (Hons), PhD, Grad Cert Ed Studies(Higher Ed)","doi":"10.1002/jppr.1827","DOIUrl":"10.1002/jppr.1827","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To compare the efficacy and safety of rituximab biosimilars to reference rituximab in patients with cancer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Data Sources</h3>\u0000 \u0000 <p>A systematic review and meta-analysis was conducted in accordance with PRISMA guidelines. MEDLINE, EMBASE, and Cochrane Central databases were searched from inception to 12 January 2022 to obtain all randomised control trial (RCTs) reporting on the safety and efficacy outcomes of patients with cancer treated with rituximab biosimilars.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Selection</h3>\u0000 \u0000 <p>All RCTs comparing the reference rituximab with a biosimilar, conducted in inpatient and outpatient settings, were included in the systematic review.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-nine RCTs were identified to report on patients treated with rituximab. The odds of achieving overall response rate in patients treated with a rituximab biosimilar compared to the reference over at least 24 weeks of treatment was 1.06 (95% confidence interval [CI] 0.88–1.26). The proportion of patients experiencing any treatment emergent adverse events were comparable between the two study arms (OR 1.20 [95% CI 0.98–1.49]).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Biosimilars for rituximab have comparable efficacy and safety profiles in treatment naïve patients; however, evidence for efficacy and safety of switching patients from reference biologic to biosimilar is lacking, and further research is required.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 5","pages":"332-356"},"PeriodicalIF":2.1,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1827","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45992323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scoping research output from tertiary hospital pharmacy departments: suggestions for improvement","authors":"Jeanie Misko B Pharm, PGDipPharm, M Pharm (Clin Pharm), PGDipOncol (Distinction), GradCertBus, GradCertHlthEcon (Distinction), FSHP,&nbsp;Matthew D. M. Rawlins B Pharm, MBA, MSHP,&nbsp;Barry Jenkins B Pharm, MSHP","doi":"10.1002/jppr.1830","DOIUrl":"10.1002/jppr.1830","url":null,"abstract":"&lt;p&gt;We read with great interest the benchmarking scoping review by Penm et al.&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; on research output from principal referral hospital pharmacy departments in Australia from 2018 to 2020. This review allows departments to compare their research output with others and encourages a strong research culture within hospital pharmacy departments.&lt;/p&gt;&lt;p&gt;The &lt;i&gt;Australian hospital peer groups&lt;/i&gt;&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; report published by the Australian Institute of Health and Welfare (AIHW) was used to determine which hospitals were classified as principal referral hospitals in the review, with principal referral hospitals defined as public acute hospitals providing a broad range of services with highly specialised service units and large patient volumes.&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; This report from 2015 remains the most recently published,&lt;span&gt;&lt;sup&gt;3&lt;/sup&gt;&lt;/span&gt; though at least two new tertiary hospitals have opened in Australia since 2015.&lt;span&gt;&lt;sup&gt;4, 5&lt;/sup&gt;&lt;/span&gt;&lt;/p&gt;&lt;p&gt;Fiona Stanley Hospital (FSH) is a 783-bed public quaternary hospital, which became fully operational in February 2015. The hospital fulfils the AIHW definition of a principal referral hospital, though it was absent from the 2015 AIHW hospital peer groups listing. The pharmacy department at FSH is making an increasing contribution to the peer-reviewed biomedical literature across a range of clinical and operational disciplines. The AIHW data also list hospitals in Western Australia (WA) which had closed by 2015 (Royal Perth Hospital Shenton Park campus and Kaleeya Hospital), as well as others which have closed subsequently, either prior to or during the 2018–2020 research window examined (Swan District Hospital and Princess Margaret Hospital for Children).&lt;span&gt;&lt;sup&gt;2&lt;/sup&gt;&lt;/span&gt; Although this is a scoping review, the hospital landscape is rapidly evolving, and we would caution against using reports that are likely to be outdated for the purposes of benchmarking. FSH pharmacy research output was not included in the scoping review,&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; suggesting that a second source was not utilised to validate the principal referral hospitals which were operational during the 2018–2020 time period.&lt;/p&gt;&lt;p&gt;Using the methods detailed in the scoping review,&lt;span&gt;&lt;sup&gt;1&lt;/sup&gt;&lt;/span&gt; we assessed the research output for the FSH pharmacy department from 2018 to 2020. Nine unique articles were located (one clinical trial, five observational studies, and three case reports). Four (44%) of these articles had a member of the pharmacy department as the first author, and eight (89%) articles had at least one author with a university affiliation. This output reflected the findings of Penm et al., Australia-wide. Adding the FSH output to the primary count resulted in a total of 21 articles (7% of the national total) published by WA pharmacy departments between 2018 and 2020.&lt;/p&gt;&lt;p&gt;We acknowledge the difficulty in obtaining current lists of Australian hospitals experienced ","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 5","pages":"402-403"},"PeriodicalIF":2.1,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1830","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47331543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How is surgical antibiotic prophylaxis prescribed for open reduction internal fixation procedures by Australian orthopaedic surgeons?","authors":"Sarah Hassan BPharm (Hons),&nbsp;Vincent Chan BSc (Hons), BPharm, MPH, PhD, GradCertAcadPrac, AACPA,&nbsp;Julie E. Stevens BSc, BPharm (Hons), PhD,&nbsp;Ieva Stupans BPharm (Hons), PhD,&nbsp;Juliette Gentle MBBS, FRACS (Orth)","doi":"10.1002/jppr.1823","DOIUrl":"10.1002/jppr.1823","url":null,"abstract":"<p>Surgical antibiotic prophylaxis (SAP) reduces the risk of surgical site infections following open reduction internal fixation (ORIF) procedures. Current guidelines recommend the use of single-dose prophylaxis for ORIF procedures. It is known that adherence to SAP guidelines is suboptimal across multiple surgical disciplines, including orthopaedic surgery. The aim of this study was to identify how Australian orthopaedic surgeons self-report prescribing of SAP for ORIF of closed fractures and whether practice adheres to recommendations in the <i>Therapeutic Guidelines: Antibiotic</i> <i>version</i> <i>16</i>. An online survey was distributed to Australian orthopaedic surgeons between August 2020 and February 2021. The survey consisted of 10 questions relating to SAP prescribing practice for ORIF of closed fractures, guideline awareness, and factors that influence prescribing. Twenty-two surgeons participated in the survey. All 22 surgeons reported prescribing the guideline-adherent agent cefazolin for ORIF procedures, with 68.2% (<i>n</i> = 15) prescribing the non-adherent agent clindamycin for patients with a severe penicillin allergy. Almost two-thirds of the surgeons (63.6%) prescribe postoperative antibiotics, with two postoperative doses the most common regimen (57.1%). Although 63.6% of surgeons were aware of guideline content, adherence to guidelines varied. Surgeons noted that multiple factors influence their prescribing practice, including knowledge gained from personal readings (77.3%), habits developed during training (68.2%), and discussion with colleagues (63.6%). Factors that influence SAP decision making for ORIF procedures are multifactorial, with variable levels of guideline adherence. This small cohort of surgeons commonly reported prescribing postoperative antibiotics. Further research is required to understand what influences SAP decision-making.</p>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 5","pages":"378-382"},"PeriodicalIF":2.1,"publicationDate":"2022-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jppr.1823","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47317787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conformity of prescription medication labels with label format and content recommendations","authors":"Yeow Boon Oh BSc (Pharm) (Hons),&nbsp;Sumithra Devi Suppiah BSc, MPharm,&nbsp;Deborah Miao-Hui Chia BSc (Pharm) (Hons), MClin Pharm, BCGP,&nbsp;Yi Wen Tan BSocSci,&nbsp;Rahul Malhotra MBBS, MD, MPH","doi":"10.1002/jppr.1824","DOIUrl":"10.1002/jppr.1824","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Prescription medication labels (PMLs) are central in guiding patients to use their medications appropriately. For PMLs to achieve this purpose, their content must enable medication use as desired and be presented in a clear and legible manner.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>This study assesses the extent to which the format and content of PMLs used in Singapore meet national and/or international recommendations, and if the extent varies across public and private healthcare institutions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>The format and content variables of 113 PMLs were compared against published recommendations. Variability in the extent to which the format and content of PMLs met the recommendations across public and private institutions was assessed through the Chi-square test or Fisher's exact test.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Less than 50% of the PMLs conformed with the format recommendations of printing instructions in sentence case (35.4%), and the content recommendations for providing drug–food administration instructions (45.3%), using specific dosing intervals for dosing instructions (21.2%), providing an expiry date (17.7%), and generating bilingual labels (5.3%). A higher proportion of private institution PMLs followed the format recommendations of printing instructions in sentence case (p = 0.004) and numeric characters for quantitative values (p = 0.003), and the content recommendations for providing drug indication (p &lt; 0.001). In contrast, a higher proportion of public institution PMLs followed the content recommendations of using specific dosing intervals (p = 0.001), providing side effects/precautions (p = 0.003), and providing drug-food administration instructions (p = 0.021).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>There is definite scope for improving the format and content of PMLs in Singapore. Future studies could explore the possible logistical, financial, and administrative reasons that contribute to PML variability across healthcare institutions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16795,"journal":{"name":"Journal of Pharmacy Practice and Research","volume":"52 6","pages":"427-437"},"PeriodicalIF":2.1,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44136435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}