Journal of Pharmacopuncture最新文献_第10页

The Highest Dosage Combination Activity Screening from the Leaf Fraction of Melastoma malabathricum with Antibiotic Gentamicin and Ciprofloxacin. 庆大霉素与环丙沙星联合筛选麦芽苋叶分最高剂量联用活性。

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-06-30 DOI: 10.3831/KPI.2022.25.2.101

Rafika Sari, Liza Pratiwi, Pratiwi Apridamayanti

{"title":"The Highest Dosage Combination Activity Screening from the Leaf Fraction of Melastoma malabathricum with Antibiotic Gentamicin and Ciprofloxacin.","authors":"Rafika Sari, Liza Pratiwi, Pratiwi Apridamayanti","doi":"10.3831/KPI.2022.25.2.101","DOIUrl":"https://doi.org/10.3831/KPI.2022.25.2.101","url":null,"abstract":"Objectives: This study aims to determine the Fractional Inhibitory Concentration Index (FICI) of combinations of Melastoma malabathricum leaf fraction with ciprofloxacin or gentamicin against pathogenic bacteria, Escherichia coli, Staphylococcus aureus, and Bacillus cereus, isolated from Diabetic Foot Ulcer (DFU) patients.Methods: We tested concentrations of 45%, 55%, 65%, and 75% of gentamicin and ciprofloxacin using dilution and agar diffusion methods. The combination of M. malabathricum leaf extract with these antibiotics was tested in vitro against all three bacteria.Results: The combination of M. malabathricum leaf extract and ciprofloxacin gave a FICI value of 0.5, indicating synergistic antibacterial activity against the test bacteria.Conclusion: The results show that the antibacterial effect of a combination of high doses of the leaf extract with either antibiotic is greater than that of the leaf extract and the antibiotics in single use.","PeriodicalId":16769,"journal":{"name":"Journal of Pharmacopuncture","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0b/68/jop-25-2-101.PMC9240403.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40594885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Severe Cervical Spondylotic Myelopathy Patient Treated with Integrative Korean Medicine Including Acupuncture, Bee Venom Pharmacopuncture and Herbal Medicine: a case report. 针灸、蜂毒药物穿刺、中药结合韩医治疗重度脊髓型颈椎病1例

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-06-30 DOI: 10.3831/KPI.2022.25.2.138

Da-Young An, Chae-Eun Kim, Suzy Han, Mi-Kyung Kim, Jun-Sang Yu, Seung-Ho Sun

引用次数: 0

A Study on the Skin Irritation Toxicity Test of Processed Sulfur in New Zealand White Rabbit 加工硫对新西兰大白兔皮肤刺激毒性试验的研究

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-03-31 DOI: 10.3831/KPI.2022.25.1.46

Hoseok Jung, Wookcheol Seo, Tae-Gyun Jeong, Hyung-Won Kang, Sungchul Kim

{"title":"A Study on the Skin Irritation Toxicity Test of Processed Sulfur in New Zealand White Rabbit","authors":"Hoseok Jung, Wookcheol Seo, Tae-Gyun Jeong, Hyung-Won Kang, Sungchul Kim","doi":"10.3831/KPI.2022.25.1.46","DOIUrl":"https://doi.org/10.3831/KPI.2022.25.1.46","url":null,"abstract":"Objectives This study was performed to evaluate the skin irritation toxicity of processed sulfur. Methods All experiments were conducted at Medvill (Korea), an institution authorized to perform non-clinical studies, under the Good Laboratory Practice (GLP) regulations. In order to investigate skin irritation toxicity of processed sulfur, we divided the back of six rabbits into two control sites and two test sites. One of each of the two control and test sites was then designated abraded sites and intact sites. In test sites, 0.5 g of processed sulfur was applied to the back of the rabbit for 24 hours, and in control sites, 0.5 g of sterile distilled water was applied in the same way. We observed and evaluated mortality, weight, general symptoms, and skin irritation toxicity. This study was conducted with the approval of the Animal Ethics Committee (Approval number IAC2020-1549). Results In all experiments, no dead animals were observed. In all cases, skin coloration was observed at 24 hours after processed sulfur administration. This coloration lasted up to 48 hours and is believed to be the effect of the administration of test substances. Weight measurement indicated that weight was lost 72 hours after administration in three cases, but this is considered an accidental weight change. Normal weight gain was observed in the remaining subjects. In all animals, no skin irritation toxicity was observed, and the primary irritation index (P.I.I) was calculated as 0.0 according to Draize’s evaluation method. Conclusion The above findings suggest that it is relatively safe to apply a processed sulfur to the skin. Further research on this topic is needed to provide more specific evidence.","PeriodicalId":16769,"journal":{"name":"Journal of Pharmacopuncture","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46884306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The Role of Bloodletting and Cupping in Severe Acute Urticaria and Angioedema as Skin Emergencies in Persian Medicine 波斯医学中放血拔罐治疗严重急性荨麻疹和血管性水肿的作用

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-03-31 DOI: 10.3831/KPI.2022.25.1.7

Maryam Taghavi Shirazi, H. M. Kenari, F. Eghbalian

{"title":"The Role of Bloodletting and Cupping in Severe Acute Urticaria and Angioedema as Skin Emergencies in Persian Medicine","authors":"Maryam Taghavi Shirazi, H. M. Kenari, F. Eghbalian","doi":"10.3831/KPI.2022.25.1.7","DOIUrl":"https://doi.org/10.3831/KPI.2022.25.1.7","url":null,"abstract":"Objectives Some dermatological diseases can be life-threatening. Urticaria and angioedema are common reasons for patients to seek treatment at an emergency department. Severe, generalized urticaria and angioedema can endanger patients’ lives by involving the airways and causing anaphylactic shock. The humor-based Persian Medicine (PM) concepts of Shara and Mashara, referring to two kinds of skin lesions, have similarities to urticaria and angioedema, respectively. This article aims to provide scientific evidence regarding the application of PM as an early intervention strategy in the emergency management of urticaria and angioedema. Methods This was a narrative review of PM studies identified by searching medical databases using search terms related to these diseases, as well as risk-associated keywords such as “fatal”, “death”, “life-threatening”, “emergency”, “cupping”, and “bloodletting”. Data were then compared, interpreted, and analyzed. Results PM scholars consider the human body as a unified whole and believe in an inner power (Nature) which stems from the body. When the presence of excessive hot substances cause an imbalance of bodily humors, Nature directs their heated vapors sharply toward the skin, thus causing Shara and Mashara. If there is a high risk of inflammation spreading to vital organs under severe conditions, urgent manual interventions are crucial. Conclusion In serious conditions of urticaria and angioedema, Fasd or bloodletting and Hijama can be effective in speeding up the control of lesions and reducing morbidity and mortality. Consequently, the development of integrated Persian and conventional medicines may provide new therapeutic pathways for skin emergencies.","PeriodicalId":16769,"journal":{"name":"Journal of Pharmacopuncture","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48931549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Hair Growth Promotion with Black Soybean Extracts: case series 黑大豆提取物促进头发生长：案例系列

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-03-31 DOI: 10.3831/KPI.2022.25.1.63

Ho-young Sung, K. Kim

引用次数: 1

Inhibition of Quorum Sensing Regulated Virulence Factors and Biofilm Formation by Eucalyptus globulus against Multidrug-Resistant Pseudomonas aeruginosa 蓝桉对多重耐药铜绿假单胞菌群体感应调控毒力因子和生物膜形成的抑制作用

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-03-31 DOI: 10.3831/KPI.2022.25.1.37

P. K. Sagar, Poonam Sharma, Rambir Singh

{"title":"Inhibition of Quorum Sensing Regulated Virulence Factors and Biofilm Formation by Eucalyptus globulus against Multidrug-Resistant Pseudomonas aeruginosa","authors":"P. K. Sagar, Poonam Sharma, Rambir Singh","doi":"10.3831/KPI.2022.25.1.37","DOIUrl":"https://doi.org/10.3831/KPI.2022.25.1.37","url":null,"abstract":"Objectives The quorum-sensing–inhibitory and anti-biofilm activities of the methanol extract of E. globulus leaves were determined against clinically isolated multidrug-resistant Pseudomonas aeruginosa. Methods The preliminary anti-quorum–sensing (AQS) activity of eucalyptus was investigated against a biosensor strain Chromobacterium violaceum ATCC 12472 (CV12472) by using the agar well diffusion method. The effect of sub-minimum inhibitory concentrations (sub-MICs) of the methanol extract of eucalyptus on different quorum-sensing–regulated virulence factors, such as swarming motility, pyocyanin pigment, exopolysaccharide (EPS), and biofilm formation, against clinical isolates (CIs 2, 3, and 4) and reference PA01 of Pseudomonas aeruginosa were determined using the swarm diameter (mm)-measurement method, chloroform extraction method, phenol (5%)-sulphuric acid (concentrated) method, and the microtiter plate assay respectively, and the inhibition (%) in formation were calculated. Results The preliminary AQS activity (violacein pigment inhibition) of eucalyptus was confirmed against Chromobacterium violaceum ATCC 12472 (CV12472). The eucalyptus extract also showed concentration-dependent inhibition (%) of swarming motility, pyocyanin pigment, EPS, and biofilm formation in different CIs and PA01 of P. aeruginosa. Conclusion Our results revealed the effectiveness of the E. globulus extract for the regulation of quorum-sensing–dependent virulence factors and biofilm formation at a reduced dose (sub-MICs) and suggest that E. globulus may be a therapeutic agent for curing and controlling bacterial infection and thereby reducing the possibility of resistance development in pathogenic strains.","PeriodicalId":16769,"journal":{"name":"Journal of Pharmacopuncture","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45257668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

A Study on the Development of a Model for Providing Traditional Korean Medicine and Welfare Services for Community Care 韩国传统医学与社区护理福利服务模式发展研究

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-03-31 DOI: 10.3831/KPI.2022.25.1.15

Eun-Jin Lee, Hee-Jung Lee, Danny Oh, Jung-Youn Park, Dongsu Kim, Sang-Nam Lee, Gihyun Lee, Ji-Yeon Lee, K. Kim, Soo-Hyun Sung

{"title":"A Study on the Development of a Model for Providing Traditional Korean Medicine and Welfare Services for Community Care","authors":"Eun-Jin Lee, Hee-Jung Lee, Danny Oh, Jung-Youn Park, Dongsu Kim, Sang-Nam Lee, Gihyun Lee, Ji-Yeon Lee, K. Kim, Soo-Hyun Sung","doi":"10.3831/KPI.2022.25.1.15","DOIUrl":"https://doi.org/10.3831/KPI.2022.25.1.15","url":null,"abstract":"Objectives This study aims to develop a community care model in traditional Korean medicine (TKM) by developing a community care participation model for the health of the elderly and deriving tasks to implement it. Methods This study implemented a group interview with experts. A fact-finding survey was conducted targeting 16 local governments that are implementing a leading project to identify the status of TKM service provision and welfare service linkage in all regions. An expert group interview (FGI) targeted public and private sector experts for each job role, the former represented by those in charge of the central government’s health care policy and administrative delivery system, and the latter by professors majoring in social welfare, professors majoring in health, and local TKM societies. After forming the expert groups, three expert group interviews were conducted. Results Through collective interviews with experts, a model for providing TKM and welfare services in community integrated care was derived by dividing it into local and central government levels. The strategies and tasks for promoting TKM-oriented health welfare services were derived from 3 strategies, 8 tasks, and 20 detailed tasks. Conclusion The core direction of the TKM health care model is the region-centered provision of TKM and welfare services. To this end, policy support for the use and linkage of health care service resources is required at the central government level, and linkage and provision of health welfare services centered on TKM are necessary through linkage and convergence between service subjects and between government health care projects.","PeriodicalId":16769,"journal":{"name":"Journal of Pharmacopuncture","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43734135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Traditional Korean Medicine Usage and Perception: a comparative study between the general population and the disabilities 韩国传统医药的使用与感知:普通人群与残疾人群的比较研究

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-03-31 DOI: 10.3831/KPI.2022.25.1.24

Ji-Eun Han, Jihye Kim, K. Kim, Ji-Yeon Lee, Soo-Hyun Sung

{"title":"Traditional Korean Medicine Usage and Perception: a comparative study between the general population and the disabilities","authors":"Ji-Eun Han, Jihye Kim, K. Kim, Ji-Yeon Lee, Soo-Hyun Sung","doi":"10.3831/KPI.2022.25.1.24","DOIUrl":"https://doi.org/10.3831/KPI.2022.25.1.24","url":null,"abstract":"Objectives This study is a comparative analysis of the satisfaction and recognition characteristics for traditional Korean medicine (TKM) in people with disabilities and the general population of Korea. Methods Here, 5,000 subjects were categorized into two groups based on a disability rating using the data from the 2017 National Survey for the Usage of Korean Medicine. The relationships among the sociodemographic characteristics, TKM usage status, recognition of TKM usage, and recognition of the effectiveness of the TKM treatment were analyzed based on the disease. The response reliability was verified using the chi-square test analysis method. Results Disabilities corresponded with low rates of high school or higher education (44%, 83.5%) and no jobs (56.9%, 33.5%), mostly the status of the low-income class with a monthly household income of < 1,500 USD (50.9%, 10.5%), poor health conditions (55.2%, 9.8%), high chronic disease prevalence rate (69.0%, 19.9%), high medical care rate (11.2%, 0.5%), and low commercial health insurance subscription rate (44%, 74.2%). Furthermore, people with disabilities visited TKM institutions more often (88.8%, 74.1%) with a high frequency TKM usage rate of ≥ 1-2 times a month (26.2%, 15.3%). They also reported that the cost of using the TKM was very high (14.7%, 8.8%) and that primarily the application of insurance benefits should be improved (52.6%, 47.5%). The treatment effectiveness for diseases was high for musculoskeletal disorders for both people with disabilities and the general population. Conclusion Preferential application of insurance benefits for musculoskeletal diseases must be extended to the TKM treatment as well, as people with disabilities have a high recognition for these conditions with TKM. It is difficult to perform randomized controlled trials on people with disability. Therefore, large-scale observational and cohort studies should be conducted. We hope this study will help establish a suitable TKM policy for people with disabilities.","PeriodicalId":16769,"journal":{"name":"Journal of Pharmacopuncture","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44780424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Qualitative Analysis of Proteins in Two Snake Venoms, Gloydius Blomhoffii and Agkistrodon Acutus Blomhoffii和Acutus两种蛇毒蛋白质的定性分析

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-03-31 DOI: 10.3831/KPI.2022.25.1.52

Su-Jeong Ha, Y. Choi, Eun-Bin Kwag, Soo-Dam Kim, Hwa-Seung Yoo, I. Kang, So-jung Park

引用次数: 0

Non-Pharmacological Treatments of Psoriasis in Persian Medicine a Narrative Review 波斯医学中银屑病的非药物治疗述评

IF 1.4

Journal of Pharmacopuncture Pub Date : 2022-03-31 DOI: 10.3831/KPI.2022.25.1.1

Farshad Mohammadian Rasanan, H. M. Kenari, M. Ghassemi, A. Sabbagh, J. Aliasl, A. Ghobadi

引用次数: 0