从蔬菜中获得的多糖:一种有效的替代赋形剂来源。

IF 1.2 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE
Ananta Choudhury, Satyabrat Sarma, Snehashis Sarkar, Madhusmita Kumari, Biplab Kumar Dey
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引用次数: 1

摘要

聚合物是药物制剂的主要构造材料,在设计有效的药物传递系统和在其应用部位释放药物方面起着主要作用。聚合物是由具有相应性质的高分子质量组分的多个重复单元组成的。大多数合成聚合物是非生物相容性的,昂贵的,并且极有可能产生不利影响。与此同时,从天然来源获得的可食用聚合物因其在现代医学中的应用前景而获得了显著的认可。此外,天然来源的聚合物通常是首选,因为它们具有某些独特的特性,如丰富的可利用性,生物相容性,无毒,经济,安全和有效的功能,符合目的。包括淀粉、纤维素、半纤维素、果胶和粘液在内的多糖被确定为一类天然获得的分子,它们作为功能性聚合物具有重要作用。本文综述了植物多糖在粘合剂、抗结块剂、粘结剂、崩解剂、乳化剂、成膜剂和增稠剂等方面的潜在作用。这只是一个机会,让我们放弃伤害我们身体的合成辅料,回到我们起源的大自然。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Polysaccharides Obtained from Vegetables: an effective source of alternative excipient.

Polysaccharides Obtained from Vegetables: an effective source of alternative excipient.

Polysaccharides Obtained from Vegetables: an effective source of alternative excipient.

Polymers are the major constructive material of pharmaceutical formulations that play a prime role in designing effective drug-delivery systems and releasing drugs at their sites of application. Polymers are composed of multiple repeating units of high molecular mass components with attendant properties. Most synthetic polymers are non-biocompatible, expensive, and extremely inclined to deliver adverse impacts. Meanwhile, edible polymers obtained from natural sources have gained remarkable recognition for their promising use in modern medicine. Moreover, polymers derived from natural sources are generally preferred due to certain of their unique features such as abundant availability, biocompatibility, nontoxicity, economical, safe, and effective functions that fit the purpose. Polysaccharides including starch, cellulose, hemicellulose, pectin, and mucilage are identified as a major class of naturally obtained molecules that have a substantial role as functional polymers. This review summarizes the potential role of polysaccharides derived from vegetable sources such as adhesives, anticaking agents, binders, disintegrants, emulsifiers, film-framing agents, and thickeners. This is simply an opportunity to abandon synthetic excipients that hurt our bodies and think back to nature from where we originate.

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来源期刊
Journal of Pharmacopuncture
Journal of Pharmacopuncture INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
2.10
自引率
7.10%
发文量
42
审稿时长
10 weeks
期刊介绍: The Journal of Pharmacopuncture covers a wide range of basic and clinical science research relevant to all aspects of the biotechnology of integrated approaches using both pharmacology and acupuncture therapeutics, including research involving pharmacology, acupuncture studies and pharmacopuncture studies. The subjects are mainly divided into three categories: pharmacology (applied phytomedicine, plant sciences, pharmacology, toxicology, medicinal plants, traditional medicines, herbal medicine, Sasang constitutional medicine, herbal formulae, foods, agricultural technologies, naturopathy, etc.), acupuncture (acupressure, electroacupuncture, laser acupuncture, moxibustion, cupping, etc.), and pharmacopuncture (aqua-acupuncture, meridian pharmacopuncture, eight-principles pharmacopuncture, animal-based pharmacopuncture, mountain ginseng pharmacopuncture, bee venom therapy, needle embedding therapy, implant therapy, etc.). Other categories include chuna treatment, veterinary acupuncture and related animal studies, alternative medicines for treating cancer and cancer-related symptoms, etc. Broader topical coverage on the effects of acupuncture, the medical plants used in traditional and alternative medicine, pharmacological action and other related modalities, such as anthroposophy, homeopathy, ayurveda, bioelectromagnetic therapy, chiropractic, neural therapy and meditation, can be considered to be within the journal’s scope if based on acupoints and meridians. Submissions of original articles, review articles, systematic reviews, case reports, brief reports, opinions, commentaries, medical lectures, letters to the editor, photo-essays, technical notes, and book reviews are encouraged. Providing free access to the full text of all current and archived articles on its website (www.journal.ac), also searchable through a Google Scholar search.
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