Journal of Pediatric Urology最新文献

{"title":"Letter to the Editor re: \"Early trajectories and re-evaluation windows after cessation of home-based transcutaneous tibial nerve stimulation in children with overactive bladder: A prospective cohort study\".","authors":"Yingyi Hu, Yan Yang, Jie Wang","doi":"10.1016/j.jpurol.2026.106270","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106270","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106270"},"PeriodicalIF":2.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor risk in patients with differences in sex development (DSD) statements and recommendations from the first update of the German guideline for DSD.","authors":"Raimund Stein, Susanne Krege, Uta Neumann, Nicole Reisch, Ursula Rosen, Olaf Hiort, Lutz Wünsch","doi":"10.1016/j.jpurol.2026.106267","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106267","url":null,"abstract":"<p><strong>Introduction: </strong>Management of gonadal tumor risk in individuals with differences of sex development (DSD) has changed considerably over recent decades. Historically, prophylactic gonadectomy was frequently performed because of concerns regarding malignant germ cell tumors (GCT). Current evidence suggests that tumor risk varies substantially between different DSD conditions and is often lower than previously assumed.</p><p><strong>Objective: </strong>To summarize current evidence regarding gonadal tumor risk in DSD and present the updated recommendations of the revised German national DSD guideline.</p><p><strong>Study design: </strong>A comprehensive literature review on gonadal tumors in DSD was performed during revision of the German national guideline. Evidence regarding epidemiology, histopathology, surveillance, biopsy strategies, fertility preservation, and gonadectomy was evaluated. Consensus recommendations were developed jointly by clinicians and patient representatives according to the available evidence.</p><p><strong>Results: </strong>Tumor risk differs considerably among DSD entities and is influenced by factors including Y chromosomal material, gonadal location, degree of gonadal dysgenesis, age, and specific genetic alterations such as TSPY or WT1 mutations. High-risk groups include complete and partial gonadal dysgenesis, particularly in the presence of Y chromosomal material. In contrast, tumor risk appears substantially lower in conditions such as androgen insensitivity syndrome, ovotesticular DSD, and congenital adrenal hyperplasia. Current management increasingly favors individualized risk assessment, surveillance, delayed gonadectomy whenever medically acceptable, and shared decision-making.</p><p><strong>Conclusion: </strong>The revised German guideline supports a more conservative and individualized approach to gonadal management in DSD. Decisions regarding surveillance and gonadectomy should balance tumor risk with endocrine function, fertility potential, psychosocial aspects, and patient autonomy. Long-term multidisciplinary follow-up in specialized DSD centers remains essential.</p>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106267"},"PeriodicalIF":2.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149062005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor re: \"Journal of Pediatric Urology Editorial Board policy statement on appropriate endpoints when conducting research on hydronephrosis/urinary tract dilation (UTD)/ureteropelvic junction obstruction (UPJO)\".","authors":"Gyanendra R Sharma, Pankaj N Maheshwari, Anshu Sharma","doi":"10.1016/j.jpurol.2026.106274","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106274","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106274"},"PeriodicalIF":2.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149030983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary to \"Analysis of short-term outcomes after antegrade sclerotherapy: A comparison of Tauber procedure variations in two pediatric centers\".","authors":"Massimo Catti","doi":"10.1016/j.jpurol.2026.106269","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106269","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106269"},"PeriodicalIF":2.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary to \"Traversing from childhood surgery to adult life: Long-term functional and psychosexual outcomes in males with differences/disorders of sex development\".","authors":"Ramesh Babu","doi":"10.1016/j.jpurol.2026.106272","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106272","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106272"},"PeriodicalIF":2.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor re: \"Stretched penile length in boys with hypospadias: Population-based analysis using validated nomogram\".","authors":"L David Livingston, R Vijaya Suriya, A Gnanavel, J Vasanthapriya","doi":"10.1016/j.jpurol.2026.106271","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106271","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106271"},"PeriodicalIF":2.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149062008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor re: \"Journal of Pediatric Urology Editorial Board policy statement on appropriate endpoints when conducting research on hydronephrosis/urinary tract dilation (UTD)/ureteropelvic junction obstruction (UPJO)\".","authors":"Caleb P Nelson, Luis H Braga, Anthony A Caldamone, C D Anthony Herndon, Magdalena Fossum, Rosalia Misseri, Raimund Stein","doi":"10.1016/j.jpurol.2026.106275","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106275","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106275"},"PeriodicalIF":2.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149039361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Commentary on \"Association of intraoperative platelet-rich fibrin (PRF) application with fistula and scar outcomes after hypospadias repair: A pilot randomized study\".","authors":"Dilan Altıntaş Ural","doi":"10.1016/j.jpurol.2026.106266","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106266","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106266"},"PeriodicalIF":2.2,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149017244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Commentary on \"Robotic approach for Wilms' tumour: Patient selection, technical considerations, and outcome analysis\".","authors":"Sujit K Chowdhary","doi":"10.1016/j.jpurol.2026.106260","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106260","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106260"},"PeriodicalIF":2.2,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A multicenter international case series highlighting the management of pediatric nephrogenic adenoma.","authors":"Johana Páez, Dana Obery, Naeem Samnakay, Andrés Gómez, Camilo Orjuela, Yair Cadena, Javier Ruiz, Florin Djendov, Imran Mushtaq, José Escala, Sonia Pérez-Bertólez, Luis García-Aparicio, Beatriz Fernández, Carlos Larios, Sibel Tiryaki, Eman Chaudhri, Juan Manuel Moldes, Pedro-José López","doi":"10.1016/j.jpurol.2026.106268","DOIUrl":"https://doi.org/10.1016/j.jpurol.2026.106268","url":null,"abstract":"<p><strong>Introduction: </strong>Nephrogenic adenoma (NA) is a rare benign epithelial lesion of the urinary tract, found most often affecting the bladder. Pediatric cases are uncommon and usually follow chronic mucosal irritation from infection, surgery, trauma, or calculi. Care must be taken when evaluating NA, as its workup and management have been incompletely described, and its morphology can resemble malignancy. This study aims to help further describe the presentation, management, and outcomes of NA.</p><p><strong>Methods: </strong>After IRB approval, we conducted a retrospective descriptive study of pediatric patients (<18 years) with histopathologically confirmed NA. Cases were collected internationally through collaboration with members of the Iberoamerican Society of Pediatric Urology (SIUP) and the European Society for Pediatric Urology (ESPU). Patients ≥18 years or with incomplete data were excluded. Demographic, clinical, histologic, treatment, recurrence, and follow-up variables were analyzed descriptively.</p><p><strong>Results: </strong>Sixteen pediatric NA cases were identified across 11 centers in 7 countries. The mean age at diagnosis was 7.6 years (median 6; range 2.5-17), and 9/16 (56%) were female. Management included transurethral resection in 7/16 (44%), open partial cystectomy in 3/16 (19%), transurethral fulguration in 2/16 (13%), intravesical sodium hyaluronate instillations in 2/16 (13%), laparoscopic-to-open cystectomy in 1/16 (6%), and surveillance in 1/16 (6%). The predominant histologic subtype was mixed tubular-papillary 10/16 (63%), and no malignant transformation was observed. Detectable recurrence occurred in 5/16 (31%) of patients after a mean interval of 12.2 months (6-24 months) and was managed with repeat endoscopic or open interventions, including intravesical sodium hyaluronate in selected cases. Mean follow-up was 4.9 years (3 months-10 years), and 10/16 (62.5%) of patients were asymptomatic with no detectable lesions on imaging at the last follow-up.</p><p><strong>Conclusion: </strong>Pediatric NA is an uncommon benign urothelial lesion characterized by bladder predominance, frequent multifocality, and a significant tendency to recur. In this international pediatric series, transurethral resection (TUR) was the most frequently used initial treatment and achieved adequate disease control in most cases, although recurrence was observed in nearly one-third of patients. Some patients managed with conservative approaches, including sodium hyaluronate instillations, experienced symptom reduction. Ultrasound was the most common first-line surveillance modality, supplemented by selective cystoscopy. Continued international collaboration is needed to better define optimal management and follow-up strategies for this rare condition.</p>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":"106268"},"PeriodicalIF":2.2,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}