Comparative study of open and robot-assisted approaches to ureteropelvic junction obstruction in children ≤ 12 months: A multi-institutional retrospective analysis.

IF 1.9 3区 医学 Q2 PEDIATRICS
Suhaib Abdulfattah, Aznive Aghababian, Sahar Eftekharzadeh, Meghan Davis, Iqra Nadeem, Sonam Saxena, Nicole J Kye, John Weaver, Hannah Bachtel, Catherine T Nguyen, Elizabeth Khusid, Christina Sze, Tenny Zhang, Kiersten Craig, Monica Xing, Katherine Fischer, Karl Godlewski, Shuvro De, Ricardo Arceo-Olaiz, Christopher Long, Dana Weiss, Chester J Koh, Ardavan Akhavan, Mohan Gundeti, Andrew J Kirsch, Arun K Srinivasan, Aseem R Shukla, Sameer Mittal
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引用次数: 0

Abstract

Background: The utilization of robot-assisted laparoscopic pyeloplasty (RALP) for the surgical correction of ureteropelvic junction obstruction (UPJO) continues to increase. The aim of this study was to determine whether robot-assisted laparoscopic pyeloplasty (RALP) is a safe and equally efficacious procedure compared to open pyeloplasty (OP) in infants ≤12 months old.

Methods: All patients ≤12 months old who underwent RALP or OP between January 2012 and January 2021 at five participating centers were included in this study. Patients who had pure laparoscopic approach, redo-pyeloplasty, ureterocalicostomy, abnormal nephro-ureteral anomalies, or lacked reviewable surgical records were excluded. Success was defined as lack of advanced endoscopic or re-do reconstructive intervention.

Results: 448 out of 497 patients met inclusion criteria: 151 RALP (34 %) and 297 OP (66 %). The median age at surgery was similar for both cohorts (p = 0.29). RALP compared to OP was associated with a higher usage of ureteral stent placement (100 % vs 88.9 %; p < 0.001) and longer procedure time (175 vs 160 min; p = 0.01), less administration of hospital morphine-equivalents post-operatively (p < 0.001) and similar length of stay (p = 0.96). There was no difference in the incidence of 30-day complications between the two groups, however higher-grade complications were seen in the OP group. Over a median follow of 26 months, the success rate after RALP and OP was 98.7 % and 89.6 % respectively (p < 0.001).

Conclusion: In this large, multi-institutional comparative series of infant pyeloplasty, our results demonstrate that RALP is not only safe and feasible, but also confers the advantages of reduced opioid usage, decreased risk of high-grade complications and decreased need for additional interventions during follow-up.

开放入路与机器人辅助入路治疗≤12个月儿童输尿管盂连接处梗阻的比较研究:一项多机构回顾性分析。
背景:机器人辅助腹腔镜肾盂成形术(RALP)在肾盂输尿管连接处梗阻(UPJO)手术矫正中的应用不断增加。本研究的目的是确定机器人辅助的腹腔镜肾盂成形术(RALP)与开放式肾盂成形术(OP)相比,在≤12个月的婴儿中是否安全且同样有效。方法:本研究纳入2012年1月至2021年1月期间在五个参与中心接受RALP或OP治疗的所有≤12个月的患者。排除单纯腹腔镜入路、肾肾盂成形术、输尿管造口术、肾输尿管异常或缺乏可回顾手术记录的患者。成功被定义为缺乏先进的内镜或重新重建干预。结果:497例患者中有448例符合纳入标准:RALP 151例(34%),OP 297例(66%)。两组患者手术时的中位年龄相似(p = 0.29)。与OP相比,RALP与输尿管支架置入率较高(100% vs 88.9%; p < 0.001)、手术时间较长(175 vs 160 min; p = 0.01)、术后医院吗啡等效物使用较少(p < 0.001)和住院时间相似(p = 0.96)相关。两组30天并发症发生率无差异,但OP组出现了更高级别的并发症。中位随访26个月,RALP和OP的成功率分别为98.7%和89.6% (p < 0.001)。结论:在这个大型的、多机构的婴儿肾盂成形术比较系列中,我们的结果表明RALP不仅安全可行,而且具有减少阿片类药物使用、降低高级别并发症风险和减少随访期间额外干预的优势。
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来源期刊
Journal of Pediatric Urology
Journal of Pediatric Urology PEDIATRICS-UROLOGY & NEPHROLOGY
CiteScore
3.70
自引率
15.00%
发文量
330
审稿时长
4-8 weeks
期刊介绍: The Journal of Pediatric Urology publishes submitted research and clinical articles relating to Pediatric Urology which have been accepted after adequate peer review. It publishes regular articles that have been submitted after invitation, that cover the curriculum of Pediatric Urology, and enable trainee surgeons to attain theoretical competence of the sub-specialty. It publishes regular reviews of pediatric urological articles appearing in other journals. It publishes invited review articles by recognised experts on modern or controversial aspects of the sub-specialty. It enables any affiliated society to advertise society events or information in the journal without charge and will publish abstracts of papers to be read at society meetings.
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