Journal of Pediatric Urology最新文献

{"title":"Letter to the editor on 'Nephron-sparing surgery in bilateral Wilms tumors: Limitations of current criteria and impact of tumor size on renal morbidity'.","authors":"Shuo Lin, Jianjie Ju, Zhouhua Wang","doi":"10.1016/j.jpurol.2025.09.037","DOIUrl":"https://doi.org/10.1016/j.jpurol.2025.09.037","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145355242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of detorsioned testes after torsion using advanced functional ultrasonography.","authors":"Irem Inanc, Mehmet Said Köprülü, Sadettin Yıldız, Fethi Emre Ustabaşıoğlu, Dincer Avlan","doi":"10.1016/j.jpurol.2025.09.035","DOIUrl":"https://doi.org/10.1016/j.jpurol.2025.09.035","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to investigate the role of advanced ultrasonographic techniques-Shear Wave Elastography (SWE) and Superb Microvascular Imaging (SMI)-in evaluating testicular parenchymal damage following surgical detorsion in patients with testicular torsion. Additionally, the study assessed the potential contribution of these modalities to clinical decision-making.</p><p><strong>Materials and methods: </strong>Seventeen patients who underwent surgical detorsion without orchiectomy for testicular torsion between January 2015 and January 2025 were included in the study. In each case, both the detorsed and contralateral testes were evaluated. Testicular volume, SMI score, and SWE values were measured using a standardized ultrasonography protocol. Between-group comparisons were performed using the Mann-Whitney U test, and correlations between continuous variables were analyzed using Spearman's rank correlation coefficient.</p><p><strong>Results: </strong>The mean age of the patients included in the study was 13.8 ± 3.6 years. In the majority of cases (76.5 %), the duration of torsion was less than 24 h. There were no statistically significant differences between detorsed and contralateral testes in terms of testicular volume, SWE values, or SMI scores (p > 0.05). However, in the detorsed group, testicular volume showed a strong negative correlation with SWE values (r = -0.6965, p = 0.002) and a positive correlation with SMI scores (r = 0.668, p = 0.003) (Tble 1).</p><p><strong>Conclusion: </strong>These findings suggest that volume measurements alone may be insufficient to accurately reflect testicular function. Functional ultrasonographic modalities such as SWE and SMI may offer substantial benefits in the postoperative monitoring of detorsed testes and in predicting long-term outcomes. These advanced imaging techniques may also facilitate more objective decision-making regarding testicular preservation versus orchiectomy.</p>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tubo-ovarian deflection facilitates access to the ureterovesical junction in robotic ureteral reimplantation for vesicoureteral reflux in children: A novel surgical modification.","authors":"Yanay Shaked, Omri Schwarztuch Gildor, Anna Itshak, Amos Neheman","doi":"10.1016/j.jpurol.2025.09.033","DOIUrl":"https://doi.org/10.1016/j.jpurol.2025.09.033","url":null,"abstract":"<p><strong>Introduction: </strong>Robot-assisted laparoscopic extravesical ureteral reimplantation (RALUR-EV) is a well-established surgical approach in girls with high-grade vesicoureteral reflux (VUR). Adequate exposure of the distal ureter and ureterovesical junction is crucial to achieve good outcomes.</p><p><strong>Methods: </strong>We present a novel modification, the medial tubo-ovarian deflection (MTOD), which improves exposure of the distal ureter by dissecting the round ligament and separating the proximal peritoneum along the white line, close to the bladder.</p><p><strong>Results: </strong>Nine girls (median age 25 months) underwent MTOD during RALUR-EV. Median console time was 105 min, and no intraoperative complications were reported. All patients were discharged the day after surgery. The short-term complications included two postoperative febrile UTIs, none of them had reflux on VCUG and one case of transient urinary retention. No ovary-related complications were reported. Median follow-up was 20 months.</p><p><strong>Conclusion: </strong>Performing MTOD during RALUR-EV is safe and reproducible, with good outcomes in short-term follow-ups.</p>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145313176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ROS scavengers and genital skin healing in boys with hypospadias","authors":"Angela K. Lucas-Herald ,&nbsp;Samra Hussain ,&nbsp;Kirsty McGinley ,&nbsp;Rheure Alves-Lopes ,&nbsp;S. Basith Amjad ,&nbsp;Martyn Flett ,&nbsp;Boma Lee ,&nbsp;Mairi Steven ,&nbsp;Stuart O'Toole ,&nbsp;S. Faisal Ahmed","doi":"10.1016/j.jpurol.2025.02.023","DOIUrl":"10.1016/j.jpurol.2025.02.023","url":null,"abstract":"<div><h3>Introduction</h3><div>Hypospadias repair is associated with high complication rates. Vascular cells from boys with hypospadias have increased reactive oxygen species (ROS) compared to controls. It is not clear if ROS affects wound healing in hypospadias.</div></div><div><h3>Objectives</h3><div>The aim of this study is to identify if cell migration and proliferation in genital skin is altered in hypospadias, and whether this is altered by antioxidants.</div></div><div><h3>Study design</h3><div>Genital skin fibroblasts (GSFs) were grown from boys undergoing hypospadias repair or routine circumcision. Cells were imaged immediately after creating a wound scratch and 48 h later, in the presence/absence of ROS scavengers, N-acetylcysteine (NAC) or Tempol. Cell migration was determined using ImageJ software. Cell proliferation was measured using a Cell Count Kit-8 (Abcam, UK).</div></div><div><h3>Results</h3><div>Twenty-four cases (median age (range) 1.8 (1.2, 6.3) years) and 28 controls (1.6 (1.2, 6.1) years) were recruited. Boys with hypospadias had impaired cell migration with reduced wound closure at 48 h (2.0 fold, p &lt; 0.0001) and reduced cell proliferation (1.3 fold, p = 0.01). External Masculinisation Score was positively correlated with wound closure (r = 0.5, p &lt; 0.0001) and cell proliferation (r = 0.3, p = 0.002). Exposure to NAC and Tempol improved wound closure (1.9 fold, p = 0.01, and 1.5 fold, p = 0.02 respectively) and cell proliferation (1.5 fold, p = 0.02 and 1.4 fold, p = 0.05 respectively).</div></div><div><h3>Discussion</h3><div>There is an association between wound healing and virilisation of the external genitalia in boys. ROS scavengers increase cell migration and proliferation in GSFs from boys with hypospadias.</div></div><div><h3>Conclusion</h3><div>Translational studies are required to confirm whether ROS scavengers may represent a therapeutic option for improving surgical outcome in boys with hypospadias.</div></div>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":"21 5","pages":"Pages 1170-1178"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hui-Jing technique for one-stage severe primary hypospadias repair: Long-term analysis compared to the Cloutier/ Bracka technique","authors":"Xiaoyu Yi ,&nbsp;Ran Zhuo ,&nbsp;Hualin Cao ,&nbsp;Tian Tao ,&nbsp;Yuandong Tao ,&nbsp;Lifei Ma ,&nbsp;Xiaoguang Zhou ,&nbsp;Yang Zhao ,&nbsp;Xiaoli Shen ,&nbsp;Pin Li ,&nbsp;Weijing Ye ,&nbsp;Huixia Zhou","doi":"10.1016/j.jpurol.2025.04.004","DOIUrl":"10.1016/j.jpurol.2025.04.004","url":null,"abstract":"<div><h3>Purpose</h3><div><span><span>This study aims to evaluate the long-term outcomes of the Hui-Jing technique (lingual mucosa combined with longitudinal preputial island flap onlay </span>urethroplasty and tubularized incised plate glansplasty), a one-stage surgical technique developed by Dr. Huixia Zhou and Dr. Weijing Ye for the severe primary </span>hypospadias repair, focusing on evaluating complication rates, functional success, and cosmetic satisfaction with comparisons to the two-stage Bracka technique.</div></div><div><h3>Materials and methods</h3><div>42 patients with severe hypospadias underwent surgery using the Hui-Jing technique between 2017 and 2019. Follow-up over a median of 72 months assessed complications and satisfaction using the Penile Perception Score (PPS), Hypospadias Objective Score Evaluation (HOSE), and International Index of Erectile Function-5 (IIEF-5) questionnaires. Data from 40 patients undergoing the Cloutier/Bracka technique served as a comparative cohort.</div></div><div><h3>Results</h3><div><span>Among the 42 Hui-Jing patients (median age 3 years), the mean operative time was 201 min, and the median follow-up period was 71 months. Complications occurred in 21 % of patients, with urethral stricture<span> in 10 %, fistula in 14 %, and </span></span>diverticulum in 2 %, compared to a higher complication rate in the Cloutier/Bracka group. Over 80 % of patients and their families provided high scores in HOSE and PPPS surveys, surpassing scores from the Bracka group. One patient (age&gt;18) completed the IIEF-5 survey, achieving a score of 24, indicating normal sexual function.</div></div><div><h3>Conclusions</h3><div>The Hui-Jing technique provides a safe and effective one-stage approach for repairing severe hypospadias, with a lower risk of complications and higher patient satisfaction.</div></div>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":"21 5","pages":"Pages 1134-1142"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-reported outcome measures in Spina Bifida from adolescence to adulthood – A systematic review","authors":"Pyry Jaakkola ,&nbsp;Seppo Taskinen ,&nbsp;Niklas Pakkasjärvi","doi":"10.1016/j.jpurol.2025.05.023","DOIUrl":"10.1016/j.jpurol.2025.05.023","url":null,"abstract":"<div><h3>Aims</h3><div>Spina bifida (SB) is a complex condition, predisposing individuals to lifelong challenges in mobility, continence, and overall health. Care modalities are multimodal, and advancements have improved survival, shifting clinical focus towards optimizing long-term function and quality of life.</div><div>The aim of this systematic review is to outline patient-reported outcome measures (PROMs) used to assess health-related quality of life (HRQOL) and other conditions in transitional SB patients, and to analyze factors influencing the results they provide.</div></div><div><h3>Methods</h3><div>We conducted a systematic review according to PRISMA guidelines, including sixteen studies with 2009 participants.</div></div><div><h3>Results</h3><div>Participants' ages ranged from 12 to 74 years, with a gender distribution of 59 % female. 72 % used CIC, 48 % had urinary incontinence and 32 % had bowel incontinence. The Pediatric Global Health 7 (PGH-7) and Neurogenic Bladder Symptom Score (NBSS) were the most frequently used tools, capturing general health and bladder-specific outcomes, respectively. The Quality of Life Assessment in Spina bifida (QUALAS) measures emerged as a concise, SB-specific tool addressing physical and psychosocial domains. CIC was linked to improved bladder-specific outcomes, though its effect on overall HRQOL was inconsistent. Mental health, literacy, and transition readiness significantly influenced HRQOL.</div></div><div><h3>Conclusions</h3><div>The use of PROMs in the treatment and research of individuals with SB proved to be surprisingly variable and fragmented. Disease-specific PROMs, such as QUALAS, are an obvious and necessary response to the problem emphasizing the continuous development of these tools to be more tailored to the target group. When complemented by targeted measures like NBSS, they offer a practical and comprehensive approach in understanding and improving HRQOL in SB patients. Optimizing bladder and bowel management, mental health, and social support remains critical for improving outcomes.</div></div><div><h3>Level of evidence</h3><div>III.</div></div>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":"21 5","pages":"Pages 1221-1232"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144326089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter to the Editor on “‘Simple Anatomical Closure-SAC’ for distal hypospadias repair without glans wings dissection: Technical description and preliminary results”","authors":"Haluk Emir,&nbsp;Ali Sezer,&nbsp;Ali Ekber Hakalmaz","doi":"10.1016/j.jpurol.2025.06.038","DOIUrl":"10.1016/j.jpurol.2025.06.038","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":"21 5","pages":"Pages 1162-1163"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to commentary on “Inguinal hernia repair timing in bladder exstrophy: A systematic review”","authors":"Niklas Pakkasjärvi,&nbsp;Christopher Gossler,&nbsp;Wolfgang Rösch","doi":"10.1016/j.jpurol.2025.06.019","DOIUrl":"10.1016/j.jpurol.2025.06.019","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":"21 5","pages":"Page 1066"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary to “Comparison of open and robot-assisted repair for ureteropelvic junction obstruction: Outcomes and direct costs from a single-institution”","authors":"Christopher E. Bayne","doi":"10.1016/j.jpurol.2025.06.033","DOIUrl":"10.1016/j.jpurol.2025.06.033","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":"21 5","pages":"Page 1260"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor on “A single center, pilot study to compare the efficacy of an instructional male genital exam video to no prior education in the quality of telemedicine consultations in pediatric urology”","authors":"Nilsun Kuas","doi":"10.1016/j.jpurol.2025.03.032","DOIUrl":"10.1016/j.jpurol.2025.03.032","url":null,"abstract":"","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":"21 5","pages":"Pages 1267-1268"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}