Staged tubularized preputial graft in proximal hypospadias, are we in the right direction?

IF 1.9 3区 医学 Q2 PEDIATRICS
Amr K Salama, Waleed Dawood, Ahmed Gaawan, Ahmed Fahmy, Mohamed Youssif, Samir Orabi, Haytham Badawy
{"title":"Staged tubularized preputial graft in proximal hypospadias, are we in the right direction?","authors":"Amr K Salama, Waleed Dawood, Ahmed Gaawan, Ahmed Fahmy, Mohamed Youssif, Samir Orabi, Haytham Badawy","doi":"10.1016/j.jpurol.2025.07.028","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Hypospadias is one of the most common congenital defects of male external genitalia. Correction of severe ventral curvature remains a main challenge to surgeons. The aim of this work was to assess short term outcomes of the staged tubularized preputial graft in primary proximal hypospadias with severe ventral curvature in our center with the hypothesis that it's comparable to published results in the two stage repair technique.</p><p><strong>Methods: </strong>A retrospective analysis of prospectively collected data that included 40 children was done, who had primary proximal hypospadias with moderate to severe ventral curvature (Study period started in December 2019 till January 2023). All patients had undergone staged tubularized preputial graft repair. Complication rates were evaluated. Cosmetic and functional outcomes were assessed using HOSE score.</p><p><strong>Results: </strong>Forty patients aged from 6 months to 8 years had proximal hypospadias with ventral curvature with a mean ventral curvature 56.13 ± 18.96° after complete penile degloving. At the second stage all grafts were taken except in two patients. Following the first stage, 4 patients only had mild residual curvature that were corrected in the second stage. Over a median (IQR) follow up of 2.9 (1.2-4.0) years after second stage, 5 patients (13.1 %) had glans dehiscence, 6 patients (15.8 %) had urethro-cutaneous fistula, 4 patients had meatal stenosis (8 %), and two patients had neourethral stricture (5.3 %). Twenty-one patients had HOSE score 15 out 16 and others had score ranged from 12 to 14.</p><p><strong>Conclusion: </strong>Repair of proximal hypospadias with severe curvature remains a challenge to paediatric urologists. A two-stage hypospadias repair with preputial grafting has achieved comparable success to other techniques. Complications (specifically glanular dehiscence and fistulas) should be explained thoroughly to the parents/caregivers which might need additional surgeries to correct it in the future.</p>","PeriodicalId":16747,"journal":{"name":"Journal of Pediatric Urology","volume":" ","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pediatric Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jpurol.2025.07.028","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Hypospadias is one of the most common congenital defects of male external genitalia. Correction of severe ventral curvature remains a main challenge to surgeons. The aim of this work was to assess short term outcomes of the staged tubularized preputial graft in primary proximal hypospadias with severe ventral curvature in our center with the hypothesis that it's comparable to published results in the two stage repair technique.

Methods: A retrospective analysis of prospectively collected data that included 40 children was done, who had primary proximal hypospadias with moderate to severe ventral curvature (Study period started in December 2019 till January 2023). All patients had undergone staged tubularized preputial graft repair. Complication rates were evaluated. Cosmetic and functional outcomes were assessed using HOSE score.

Results: Forty patients aged from 6 months to 8 years had proximal hypospadias with ventral curvature with a mean ventral curvature 56.13 ± 18.96° after complete penile degloving. At the second stage all grafts were taken except in two patients. Following the first stage, 4 patients only had mild residual curvature that were corrected in the second stage. Over a median (IQR) follow up of 2.9 (1.2-4.0) years after second stage, 5 patients (13.1 %) had glans dehiscence, 6 patients (15.8 %) had urethro-cutaneous fistula, 4 patients had meatal stenosis (8 %), and two patients had neourethral stricture (5.3 %). Twenty-one patients had HOSE score 15 out 16 and others had score ranged from 12 to 14.

Conclusion: Repair of proximal hypospadias with severe curvature remains a challenge to paediatric urologists. A two-stage hypospadias repair with preputial grafting has achieved comparable success to other techniques. Complications (specifically glanular dehiscence and fistulas) should be explained thoroughly to the parents/caregivers which might need additional surgeries to correct it in the future.

尿道下裂近端分阶段管状包皮移植,我们的方向对吗?
背景:尿道下裂是男性外生殖器最常见的先天性缺陷之一。矫正严重的腹侧弯曲仍然是外科医生面临的主要挑战。这项工作的目的是评估分阶段管状包皮移植物治疗原发性近端尿道下裂的短期效果,假设它与已发表的两阶段修复技术的结果相当。方法:回顾性分析前瞻性收集的数据,包括40名患有原发性近端尿道下裂并伴有中度至重度腹侧弯曲的儿童(研究期间从2019年12月开始至2023年1月)。所有患者均进行了分阶段管状包皮移植修复。评估并发症发生率。使用HOSE评分对美容和功能结果进行评估。结果:40例患者,年龄6个月~ 8岁,阴茎完全脱套后尿道下裂近端腹侧弯曲,平均腹侧弯曲56.13±18.96°。在第二阶段,除两名患者外,所有患者均接受移植物移植。在第一阶段之后,4例患者只有轻微的残余弯曲,在第二阶段进行了纠正。二期后中位(IQR)随访2.9(1.2-4.0)年,5例(13.1%)患者出现龟头开裂,6例(15.8%)患者出现尿道-皮瘘,4例(8%)患者出现金属狭窄,2例(5.3%)患者出现神经尿道狭窄。21例患者的HOSE评分为15分,其余患者的评分范围为12至14分。结论:严重弯曲的近端尿道下裂的修复对儿科泌尿外科医生来说仍然是一个挑战。包皮移植两期尿道下裂修复术与其他技术相比取得了相当的成功。并发症(特别是腺体破裂和瘘管)应向父母/护理人员充分解释,将来可能需要额外的手术来纠正它。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Pediatric Urology
Journal of Pediatric Urology PEDIATRICS-UROLOGY & NEPHROLOGY
CiteScore
3.70
自引率
15.00%
发文量
330
审稿时长
4-8 weeks
期刊介绍: The Journal of Pediatric Urology publishes submitted research and clinical articles relating to Pediatric Urology which have been accepted after adequate peer review. It publishes regular articles that have been submitted after invitation, that cover the curriculum of Pediatric Urology, and enable trainee surgeons to attain theoretical competence of the sub-specialty. It publishes regular reviews of pediatric urological articles appearing in other journals. It publishes invited review articles by recognised experts on modern or controversial aspects of the sub-specialty. It enables any affiliated society to advertise society events or information in the journal without charge and will publish abstracts of papers to be read at society meetings.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信