Journal of pediatric and adolescent gynecology最新文献

{"title":"Exploring the Association Between Sleep Quality and Menstrual Abnormalities in Adolescents.","authors":"Jessica N Zhang, Grace K Sarris, Daniela G Fernandez-Bergnes, Tatiana M Salloum, Katherine M Hofmann, Edith Duncan, Judith S Simms-Cendan","doi":"10.1016/j.jpag.2025.08.001","DOIUrl":"https://doi.org/10.1016/j.jpag.2025.08.001","url":null,"abstract":"<p><strong>Study objective: </strong>This study aims to assess the association between sleep quality and menstrual cycle abnormalities in adolescent females in the United States (U.S.). In doing so, we address the gap in adolescent menstrual health by providing baseline data that can inform future sleep and menstrual health interventions.</p><p><strong>Methods: </strong>An Institutional Review Board (IRB) approved, anonymous survey was distributed to new patients at an academic pediatric gynecology clinic. Exclusion criteria included age over 21, hormonal contraceptive use, prior chemotherapy, or reproductive disorders. Electronic consent was obtained. The survey included the Pittsburgh Sleep Quality Index (PSQI), menstrual cycle data, comorbidities, and demographic data. Continuous variables were analyzed using linear regression and categorical variables using chi-square (with p < .05 considered significant). Odds ratios (OR) were reported with 95% confidence intervals (CI).</p><p><strong>Results: </strong>Among the 100 analyzed responses, 84.0% identified as Hispanic, with over one-third (37.0%) being born outside of the U.S. Sixty-three had poor sleep quality (PSQI > 5), and 64 had abnormal menses. Higher PSQI scores were significantly associated with abnormal menses (OR = 1.15, CI = 1.01, 1.32, p = .04). Poor sleep correlated with prior anxiety (χ² = 6.84, p = .01) and depression diagnoses (χ² = 3.89, p = .05).</p><p><strong>Conclusion: </strong>Our findings suggest a significant relationship between poor sleep quality and menstrual abnormalities, emphasizing the need to evaluate sleep when managing adolescent menstrual health. Future research is needed to gain deeper insights into the mechanistic link between the two and the broader implications of this association.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144847099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction notice to A Novel Ovarian Reserve Monitoring Algorithm for Patients at Risk of Ovarian Injury from Gonadotoxic Therapy [Journal of Pediatric and Adolescent Gynecology 38 (2025) 219]","authors":"Guluzar Turan ,&nbsp;Victoria Kennerley ,&nbsp;Marie-Teresa Colbert ,&nbsp;Marcy Hoath ,&nbsp;Kamilah Abdur-Rashid ,&nbsp;Mikayla Ecker ,&nbsp;Mary Sammel ,&nbsp;Leslie Appiah","doi":"10.1016/j.jpag.2025.07.001","DOIUrl":"10.1016/j.jpag.2025.07.001","url":null,"abstract":"","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":"38 5","pages":"Page 644"},"PeriodicalIF":1.8,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145048025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex Hormone Replacement Therapy and Bleeding Patterns among Adolescents and Young Adult Females with Prader-Willi Syndrome.","authors":"Julie C Friedman, Kendra Hutchens, Hava Starkman, Laurel E Beaty, Mary D Sammel, Erin Finn, Leslie C Appiah, Veronica I Alaniz, Christine L Chan","doi":"10.1016/j.jpag.2025.07.011","DOIUrl":"https://doi.org/10.1016/j.jpag.2025.07.011","url":null,"abstract":"<p><strong>Introduction: </strong>Prader-Willi Syndrome (PWS) is associated with hypogonadism. Limited data exist on guidelines for sex hormone replacement therapy (HRT) in females with PWS. We aimed to characterize pubertal timing, vaginal bleeding patterns, and HRT practices in adolescent and young adult females with PWS.</p><p><strong>Methods: </strong>We conducted a retrospective review of females ages 5 to 25 years, diagnosed with PWS, at a single institution (01/2013-09/2023). Demographic and clinical data were abstracted from electronic medical records and analyzed with descriptive statistics. Patients were classified as having complete hypogonadotropic hypogonadism (HH) (luteinizing hormone [LH] <0.3 mIU/mL or lack of thelarche by 13 years) or partial hypogonadism (PH) (LH >0.3 mIU/mL and estradiol <20 pg/mL or amenorrhea by 15 years).</p><p><strong>Results: </strong>Fifty-one patients met inclusion criteria; 21 (41%) were diagnosed with hypogonadism and were included in the final analysis. Of these, 8 (38.1%) had HH and 13 (61.9%) PH. Delayed puberty was diagnosed at a median of 13.5 years (range: 10-15) in the HH cohort and at 14.5 years (range: 13-18) in the PH cohort. Six patients (28.6%) reported spontaneous vaginal bleeding, median age of 14.0 (range: 10-16) years. Eighteen patients (85.7%) were prescribed HRT at a median of 14.0 (range: 12-21) years, of which 8 (44.4%) discontinued HRT, with half reporting breakthrough bleeding.</p><p><strong>Discussion: </strong>Hypogonadism is common among adolescent and young adult females with PWS. We found high rates of HRT discontinuation primarily due to breakthrough bleeding. These findings highlight the need to tailor HRT regimens and identify strategies to encourage HRT adherence to optimize long-term outcomes.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perception and Attitude towards Fertility and Fertility Preservation Options in Parents of Children with Turner Syndrome: A Qualitative Survey Study.","authors":"Victoria H Bustamante Velez, Tazim Dowlut-McElroy, Roopa Kanakatti Shankar","doi":"10.1016/j.jpag.2025.07.008","DOIUrl":"https://doi.org/10.1016/j.jpag.2025.07.008","url":null,"abstract":"<p><strong>Study objective: </strong>Turner Syndrome (TS) is a genetic condition often characterized by ovarian insufficiency and infertility. Fertility preservation discussions are recommended early in care, but few studies have explored parental perspectives. Our objective was to assess the knowledge, perceptions, and attitudes regarding fertility and fertility preservation among parents of young children with TS.</p><p><strong>Methods: </strong>An anonymous bilingual survey (English/Spanish) was completed by parents of children under 12 years with TS seen at a multidisciplinary clinic (April 2022 -September 2023). Quantitative data were analyzed using descriptive statistics and Fisher's exact test. Open-ended responses were analyzed using conventional content analysis to identify recurring themes.</p><p><strong>Results: </strong>Forty-five parents (82% mothers) completed the survey, with 60% identifying as non-Hispanic white (NHW), 20% Hispanic, 11% Black, and 9% other. All were aware of the association of infertility with TS. NHW respondents were more likely to have a higher income, educational status and private insurance (p<0.05). We found differences by race/ethnicity regarding the value of biological parenthood and openness to fertility preservation options as well as factors that contribute to these decisions. Cost emerged as a major consideration across all income groups. Despite high counseling rates (>90%), only 60% of parents recalled fertility discussions. Themes from open-ended responses emphasized cost, procedural risk/benefit, child autonomy, divergent opinions on timing of counseling, and a desire for more information.</p><p><strong>Conclusion: </strong>This study highlights the varied perspectives and priorities voiced by parents of young children with TS regarding fertility preservation and can inform fertility counseling practices by providers.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraoperative care and complications of symptomatic adolescent and young adult patients undergoing laparoscopy to diagnose and/or to treat endometrioses: A Multi-Institutional Review.","authors":"Jacquelyn R Evans, Katherine Bergus, Lindsey Asti, Lesley L Breech, Ruiqi Cen, Yuan Yuan Gong, S Paige Hertweck, Holly R Hoefgen, Anne H Horne, Ashli Lawson, Seema Menon, Kathleen E O'Brien, Shashwati Pradhan, Brenna Rachwal, Yolanda R Smith, Priya Suvarna, Sarah Van Son, Geri Hewitt","doi":"10.1016/j.jpag.2025.07.010","DOIUrl":"https://doi.org/10.1016/j.jpag.2025.07.010","url":null,"abstract":"<p><strong>Study: </strong>This multi-institutional, retrospective study explores the risks of laparoscopy for diagnosis and treatment of endometriosis to facilitate shared medical decision-making in patients age < 22 years old with chronic pain considering surgery.</p><p><strong>Methods: </strong>A retrospective review of patients less than 22 years old who had surgically proven endometriosis at eight pediatric hospitals was completed. Patient demographics, operative interventions, concurrent procedures, and complications were evaluated.</p><p><strong>Results: </strong>There were 284 patients with pathologically confirmed endometriosis with a median age of 16.86 years (15.51, 18.06). During the index procedure, diagnostic biopsy alone was performed (35.92%), followed by ablation (29.93%), excision (20.07%), excision and ablation (12.68%), and cryoablation (1.41%). Most common procedures performed concurrently included LNG-IUS placement (58.10%), ovarian cystectomy (11.27%), endoscopy (1.76%), and appendectomy (1.41%). Most patients (86.27%) experienced no postoperative complications within 30 days of the procedure. Significant postoperative pain was seen in 14 patients (4.93%) with 9 patients (3.17%) requiring additional narcotics and 5 patients (1.76%) requiring admission for pain control. One patient experienced a venous thromboembolism (0.35%). Reoperation rate was 12.32% with a median interval of 1.7 years (IQR: 0.93, 4) from initial surgery.</p><p><strong>Conclusions: </strong>We demonstrate that laparoscopy for diagnosis and/or treatment of endometriosis has low complication and reoperation rates in adolescent and young adult patients. Performing concurrent indicated procedures, particularly LNG-IUS placement, is safe and should be considered to avoid additional anesthesia exposure and cost. Anticipatory guidance regarding postoperative pain may be beneficial in this patient population. This evidence-based data aids in shared medical decision-making.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant Mitotically Active Cellular Fibroma of the Ovary in an a Adolescent.","authors":"Bade Toker Kurtmen, Dilnur Sevinc, Gürdeniz Serin, Emine Burcu Cigsar Kuzu","doi":"10.1016/j.jpag.2025.07.009","DOIUrl":"https://doi.org/10.1016/j.jpag.2025.07.009","url":null,"abstract":"<p><p>This case report describes a 15-year-old adolescent diagnosed with mitotically active cellular fibroma (MACF) of the ovary. Cellular fibromas account for approximately 10% of all ovarian fibromas. While malignant fibrosarcomas are characterized by aggressive behavior, high mitotic activity, and nuclear atypia, MACFs are considered intermediate tumors, lying between cellular fibromas and fibrosarcomas in terms of mitotic activity and malignant potential. Herein, we present the case of the largest and heaviest MACF mass reported in a pediatric patient in the literature.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thickness and Contractile Performance of Lateral Abdominal Muscles and Diaphragm in Young Adult and Nulliparous Women with Primary Dysmenorrhea.","authors":"Seyda Toprak Celenay, Mehtap Balaban, Nida Lalecan, Gamze Yilmaz, Bilge Ipek Torun","doi":"10.1016/j.jpag.2025.07.006","DOIUrl":"https://doi.org/10.1016/j.jpag.2025.07.006","url":null,"abstract":"<p><strong>Objective: </strong>To compare the thickness and contractile performance (CP) of the transversus abdominis (TrA) and internal oblique (IO) muscles and diaphragm in young adult and nulliparous women with and without primary dysmenorrhea (PD).</p><p><strong>Methods: </strong>Women with (PD group, n=30) and without PD (Control group, n=30) were included. Menstrual pain intensity with a 10-cm Visual Analogue Scale was assessed. TrA and IO thickness both in a resting state and during the abdominal drawing-in maneuver (ADIM) with 11 MHz linear probe, diaphragm thickness at the end of maximum inspiration and expiration with 1-6 MHz convex probe were measured. The calculation of the percentage of change (PC) in both the thickness and CP of these muscles was conducted.</p><p><strong>Results: </strong>The mean pain intensity of PD group was found as 7.18±1.22 cm. No difference was detected between groups in terms of the thickness of the TrA and IO muscles at rest and during ADIM and the thickness of the diaphragm at the end of deep inspiration and expiration (p>0.05). PC in thickness and CP of the TrAright and TrAleft muscles were less in the PD group than the control group (p<0.05). No difference was found between groups in terms of PC in thickness and CP of IOright, IOleft and diaphragm (p>0.05).</p><p><strong>Conclusions: </strong>PC in thickness and CP of TrA muscle were less in women with PD than women without PD. Therefore, it may be important to consider the decreased PC in the TrA muscle thickness with the ADIM as compared to the thickness at rest and to provide exercise training in management of PD.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144731899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Piloting a Birth Control Navigator Program for Adolescents and Young Adults in Indiana.","authors":"Tracey A Wilkinson, Faith Coleman, Natasha Chaku, Jeffrey F Peipert, Sarah E Wiehe, Aaron E Carroll, J Dennis Fortenberry","doi":"10.1016/j.jpag.2025.07.004","DOIUrl":"10.1016/j.jpag.2025.07.004","url":null,"abstract":"<p><strong>Objectives: </strong>While increasing access to contraception is important, young people often face barriers to access prior to, within and after engagement with clinical care. The objective was to examine the feasibility of a pilot adolescent and young adult (AYA) birth control navigator program.</p><p><strong>Methods: </strong>An online and in-person outreach strategy was launched in central Indiana starting in June 2023 to reach AYA outside of clinical settings and connect them to a trained navigator. Various communication platforms were used and a link to a validated contraception decision aid and barrier assessment was sent. After program support, AYA were invited to participate in a research cohort and complete a baseline survey.</p><p><strong>Results: </strong>The outreach strategy included social media advertising with 4,327,614 impressions and 30,210 clicks and 17 social media ambassadors with 96 posts. Of the 30 people that connected with the navigator, 18 (60%) participated in the post-programmatic research cohort. Participants had a mean age of 17.3yrs (range 15-19), 33% identified as African American and 61% reported being sexually active. Addressed barriers included appointment booking (73%), access confidential care (67%) and support around transportation (30%). All participants (100%) reported that the navigator listened to them, provided helpful information, and made them feel comfortable. However, only 8 (67%) reported high-quality person-centered care was experienced during clinical encounters.</p><p><strong>Conclusions: </strong>A human-centered designed birth control navigator pilot program can provide AYA's personalized assistance with overcoming barriers faced. Recruitment outside of clinical environments of AYA in a restrictive state was challenging, despite online outreach strategies.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12324822/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing Medical Abortion Outcomes and Experiences Between Young and Adult Women: Evidence From Urban Cambodia.","authors":"Erin Pearson, Paige Logan, Elisabeth Eckersberger, Jamie Menzel, Bunsoth Mao, Sovanthida Suy, Vonthanak Saphonn, Nathalie Kapp","doi":"10.1016/j.jpag.2025.07.007","DOIUrl":"10.1016/j.jpag.2025.07.007","url":null,"abstract":"<p><strong>Introduction: </strong>Self-managed abortions are increasingly common globally, but little is known about young women's experiences.</p><p><strong>Methods: </strong>Secondary analysis of data from 1847 women accessing MA in urban Cambodia in 2018-2019 and in-depth interviews with seven women aged 15-19. Descriptive statistics compared young and adult women on self-reported abortion outcomes and experiences in clinics and pharmacies, and qualitative data contextualized quantitative findings.</p><p><strong>Results: </strong>Young women were better represented among clinic clients (30.0%) compared to pharmacy clients (20.2%). Young women had comparable MA success rates and better MA experiences across settings, but young pharmacy clients were more likely to seek support from friends and family.</p><p><strong>Discussion: </strong>Young women had comparable MA outcomes and experiences as adult women in both clinics and pharmacies, but young women self-managing their abortions may require information and support beyond the pharmacist.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Provision of Person-Centered Contraceptive Care to Adolescents: Results From a National Survey of Family Planning Clinics.","authors":"Jennifer Mueller, Tamrin A Tchou, Madeleine Haas, Priscille Osias, Laura D Lindberg, Alicia VandeVusse","doi":"10.1016/j.jpag.2025.07.005","DOIUrl":"10.1016/j.jpag.2025.07.005","url":null,"abstract":"<p><strong>Study objective: </strong>Access to contraceptive services is essential for adolescents to pursue sexual and reproductive well-being. Publicly supported family planning clinics are critical reproductive health safety net providers and are an essential source of contraceptive care for adolescents. Contraceptive care for adolescents should be centered on their needs to ensure reproductive autonomy.</p><p><strong>Methods: </strong>We fielded a national survey of publicly supported family planning clinics in the United States and conducted a cross-sectional analysis to understand the extent to which these clinics provide contraceptive services that are adolescent-centered. We also examined differences by clinic type and by state policies on adolescents' consent to contraceptive care.</p><p><strong>Results: </strong>Many clinics have taken strides to provide adolescent-centered contraceptive care, but gaps in this care still exist, particularly among federally qualified health centers.</p><p><strong>Conclusion: </strong>Gaps in the provision of adolescent-centered care should be addressed to ensure that adolescent populations are receiving high quality contraceptive care.</p>","PeriodicalId":16708,"journal":{"name":"Journal of pediatric and adolescent gynecology","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}