Journal of Ophthalmology最新文献

{"title":"RETRACTION: Efficacy of Subconjunctival Bevacizumab Injections before and after Surgical Excision in Preventing Pterygium Recurrence.","authors":"Journal Of Ophthalmology","doi":"10.1155/joph/9895280","DOIUrl":"https://doi.org/10.1155/joph/9895280","url":null,"abstract":"<p><p>[This retracts the article DOI: 10.1155/2017/6824670.].</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"9895280"},"PeriodicalIF":2.2,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13674382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum Lipid Profile, Atherogenic Indices, and Systemic Inflammatory Markers in Retinal Vein Occlusion: A Retrospective Case-Control Study.","authors":"Nurcan Gürsoy, Şenay Deniz","doi":"10.1155/joph/6862613","DOIUrl":"10.1155/joph/6862613","url":null,"abstract":"<p><strong>Purpose: </strong>Retinal vein occlusion (RVO) is a common retinal vascular disorder associated with systemic vascular and metabolic risk factors. Although both dyslipidemia and inflammation have been implicated in its pathogenesis, the associations of conventional lipid parameters, derived atherogenic indices, and hemogram-derived inflammatory markers with RVO remain incompletely characterized.</p><p><strong>Methods: </strong>This retrospective, single-center, case-control study included 81 patients with RVO and 91 controls without RVO. Hospital records from January 2025 through December 2025 were reviewed. Conventional lipid parameters, derived atherogenic indices, and systemic inflammatory markers were compared between groups. Multivariable logistic regression analyses were performed using separate models for conventional lipid parameters, derived lipid indices, and inflammatory indices to reduce collinearity and improve interpretability.</p><p><strong>Results: </strong>Patients with RVO were older than controls and had significantly higher monocyte, neutrophil, and leukocyte counts, as well as higher C-reactive protein (CRP), low-density lipoprotein cholesterol (LDL-C), triglyceride, total cholesterol, and non-high-density lipoprotein cholesterol (non-HDL-C) levels. Among the derived indices, total cholesterol/high-density lipoprotein cholesterol (HDL-C), LDL-C/HDL-C, and non-HDL-C/HDL-C ratios were significantly higher in the RVO group, whereas neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), neutrophil-to-platelet ratio (NTR), hemoglobin-albumin-lymphocyte-platelet (HALP) score, systemic immune-inflammation index (SII), and triglyceride/HDL-C ratio were comparable between groups. In models adjusted for age, sex, and CRP, LDL-C, non-HDL-C, and total cholesterol were associated with RVO, whereas triglyceride was not. Total cholesterol/HDL-C, LDL-C/HDL-C, and non-HDL-C/HDL-C ratios were also associated with RVO in models adjusted for age, sex, and CRP, whereas triglyceride/HDL-C was not. None of the evaluated inflammatory indices was associated with RVO in models adjusted for age and sex.</p><p><strong>Conclusions: </strong>In this dataset, several cholesterol-related variables were associated with RVO in models adjusted for age, sex, and CRP, whereas none of the evaluated hemogram-derived inflammatory indices was associated with RVO in models adjusted for age and sex. Because these variables were examined in separate models with different covariate adjustments, the findings do not establish the superiority or greater relative importance of lipid markers.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"6862613"},"PeriodicalIF":2.2,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13671100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Efficacy of Phacoemulsification Combined With Trabeculectomy for Advanced Chronic Primary Angle-Closure Glaucoma With Cataract: A 3-Year Retrospective Study.","authors":"Chunxin Lai, Baodi Yang, Suwen Zhao, Ling Li, Shuilian Chen, Yongyi Niu, Junhong Fang, Yongjie Qin, Hongyang Zhang","doi":"10.1155/joph/3442493","DOIUrl":"10.1155/joph/3442493","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the long-term efficacy of phacoemulsification combined with trabeculectomy (Phaco-Trab) for advanced chronic primary angle-closure glaucoma (PACG) with cataract.</p><p><strong>Methods: </strong>Patients with advanced chronic PACG coexisting with cataracts who underwent Phaco-Trab were enrolled. The morphologic structures of filtering blebs, including characteristics under slit-lamp examination, anterior segment optical coherence tomography (AS-OCT), and in vivo confocal microscopy (IVCM), were used to evaluate the filtering function.</p><p><strong>Results: </strong>A total of 30 eyes from 27 patients were enrolled. The mean preoperative intraocular pressure (IOP) of 19.98 ± 6.48 mmHg significantly decreased to 13.73 ± 2.35 mmHg at year 3 (<i>p</i> < 0.0001). A statistically significant decrease in postoperative IOP-lowering medications was observed, but the number of drugs used increased annually (0.50 ± 0.82 at year 1, 1.00 ± 0.98 at year 2, and 1.47 ± 0.97 at year 3, <i>p</i> < 0.0001). Following Phaco-Trab, a high surgical qualified success rate was maintained over 3 years (93.3% at year 1, 90.0% at year 2, and 80.0% at year 3, <i>p</i> = 0.117). However, the complete success rate significantly decreased each year (70.0% at year 1, 36.7% at year 2, and 20.0% at year 3, <i>p</i> < 0.0001), along with an increase in the rate of failure filtering blebs, reaching 46.7%, 83.3%, and 90.0% at each time point (<i>p</i> < 0.0001). Overall, 46.7% (14/30) of participants developed complications and required postoperative procedures after Phaco-Trab, which were mainly induced by the trabeculectomy procedure.</p><p><strong>Conclusions: </strong>Phaco-Trab can significantly lower IOP and reduce the use of IOP-lowering medications for advanced chronic PACG with cataracts, but it is associated with a higher rate of complications and a higher failure rate of the filtering bleb.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"3442493"},"PeriodicalIF":2.2,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13669659/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discrepancy Between Preoperative and Intraoperative Central Corneal Epithelial Thickness During Alcohol-Assisted PRK.","authors":"Dana Barequet, Nadav Levinger, Oren Golan, Samuel Levinger, Irina Barequet","doi":"10.1155/joph/4117242","DOIUrl":"https://doi.org/10.1155/joph/4117242","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the agreement between preoperative optical coherence tomography (OCT)-derived central corneal epithelial thickness (CET) and an intraoperative epithelial thickness estimate derived from optical coherence pachymetry (OCP) during alcohol-assisted photorefractive keratectomy (PRK).</p><p><strong>Methods: </strong>A retrospective analysis was performed on 116 eyes of 58 consecutive patients who underwent bilateral myopic alcohol-assisted PRK between June 2020 and October 2021. Preoperative CET was assessed using anterior-segment OCT. The OCP-derived intraoperative epithelial thickness estimate was calculated as the difference between total corneal pachymetry readings obtained immediately before and after epithelial removal. Demographic, preoperative clinical, and refractive data, as well as intraoperative laser parameters, were collected.</p><p><strong>Results: </strong>Mean age was 26.31 ± 7.44 years (range, 18-45), and 63.8% of patients were female. Mean sphere and spherical equivalent were -3.49 ± 1.63D and -3.16 ± 1.63D, respectively. Mean preoperative OCT-derived CET was 53.2 ± 3.5  μm (range, 42-69  μm), whereas the mean OCP-derived intraoperative CET was significantly higher at 59.8 ± 14.8  μm (range, 21-99  μm; <i>p</i> < 0.0001). This discrepancy was consistent in both eyes of each patient. The intraoperative estimate exceeded the preoperative OCT-derived CET in 73.3% of eyes. Bland-Altman analysis demonstrated poor agreement between the two approaches, with wide limits of agreement from -15.7  μm to +34.8  μm. Preoperatively, 98.3% of eyes had CET values within the 40-60-μm range, compared with 44.8% of the OCP-derived intraoperative estimates. The difference between measurements significantly correlated with preoperative corneal thickness (<i>r</i> = 0.45, <i>p</i> < 0.001) and intraoperative CET (<i>r</i> = 0.97, <i>p</i> < 0.0001) but not refractive error or intraoperative and environmental parameters.</p><p><strong>Conclusion: </strong>Preoperative OCT-derived CET and OCP-derived intraoperative CET demonstrate a systematic discrepancy and poor agreement during alcohol-assisted PRK. The intraoperative estimates were higher on average and substantially more variable than preoperative OCT measurements. These differences may have implications for surface ablation procedures, particularly transepithelial PRK, in which an assumed epithelial thickness profile is incorporated into treatment planning.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"4117242"},"PeriodicalIF":2.2,"publicationDate":"2026-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13655383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149182708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical Coherence Tomography Predictors of Anatomical and Functional Recovery After Macular Hole Surgery.","authors":"Ahmet Mehmet Somuncu, Mehmet Kola, Hidayet Erdöl, Büşra Köse, Mahmut Cenap Esenülkü","doi":"10.1155/joph/5093898","DOIUrl":"10.1155/joph/5093898","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;To examine whether preoperative optical coherence tomography (OCT)-derived macular hole parameters and postoperative outer retinal restoration are associated with anatomical closure and visual recovery after macular hole surgery and to determine whether preoperative geometry and preoperative symptom duration predict different outcome domains.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This retrospective study included 48 eyes of 45 patients who underwent surgery for macular hole between January 1, 2013, and August 1, 2019, and completed at least 6 months of follow-up. Surgery consisted of 23-gauge pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling; an inverted ILM flap was additionally used in 18 eyes (37.5%) and autologous blood in 4 eyes (8.3%). Combined phacoemulsification was performed in 12 eyes (25.0%). Best-corrected visual acuity (BCVA) was recorded preoperatively and at Postoperative Months 1, 3, and 6. Preoperative OCT measurements included minimum hole diameter, basal hole diameter, hole height, macular hole index (MHI), tractional hole index (THI), diameter hole index (DHI), and hole form factor (HFF). Between-group differences are reported with Cohen's &lt;i&gt;d&lt;/i&gt; and 95% confidence intervals (CIs), and a multivariable linear regression model was constructed for Month-6 BCVA.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The cohort comprised 23 women (51.1%) and 22 men (48.9%) with a mean age of 68.4 ± 8.7 years. Anatomical success was achieved in 38 eyes (79.2%), and functional success in 36 eyes (75.0%). BCVA improved significantly through postoperative Month 6. Larger minimum and basal hole diameters were associated with worse postoperative BCVA, whereas higher MHI and THI values were associated with better postoperative BCVA. Eyes with preserved external limiting membrane (ELM) and/or ellipsoid zone (EZ) integrity at postoperative Months 3 and 6 had significantly better visual outcomes. Symptom duration was the dominant correlate of anatomical closure, and its association with BCVA strengthened across follow-up (&lt;i&gt;r&lt;/i&gt; = 0.523 preoperatively to &lt;i&gt;r&lt;/i&gt; = 0.808 at Month 6) while that of THI weakened over the same interval. HFF was the only preoperative geometric parameter that differed between closure patterns (&lt;i&gt;d&lt;/i&gt; = 0.86; 95% CI for the mean difference, 0.024 to 0.272; &lt;i&gt;p&lt;/i&gt; = 0.036), yet it showed no association with BCVA at any time point. In a multivariable analysis, preoperative BCVA and Month-6 EZ integrity were the only independent correlates of Month-6 BCVA (adjusted &lt;i&gt;R&lt;/i&gt;-squared = 0.76).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Preoperative OCT morphology is clinically informative in macular hole surgery. Minimum and basal hole diameters, MHI, and THI may help estimate postoperative visual recovery, while restoration of the ELM and EZ appears closely related to better functional outcome. In this cohort, the determinants of the two outcome domains were largely dissociable: preoperative geo","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"5093898"},"PeriodicalIF":2.2,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13646894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149137323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on a New Model for Predicting Vault After Implantable Collamer Lens (ICL) Based on Structural Parameters of the Posterior Chamber.","authors":"Qin Wang, Rundong Yang, Qizhi Zhou","doi":"10.1155/joph/5298174","DOIUrl":"10.1155/joph/5298174","url":null,"abstract":"<p><strong>Objective: </strong>To fit a new prediction model of the implantable collamer lens (ICL) vault including the parameters of the posterior chamber structure and to validate the accuracy of the new model.</p><p><strong>Methods: </strong>Seventy patients (92 eyes) undergoing ICL implantation were enrolled in the prediction model group. Spearman's rank correlation was used for univariate analysis to assess the relationship between postoperative vault and preoperative ocular parameters. A vault prediction model was developed using multiple linear regression. An independent validation cohort comprised 140 patients (204 eyes) who received ICL implantation. All patients completed preoperative ocular examinations. Postoperative vault was measured at 1 month. We calculated the proportion of eyes with optimal vault (250-1000 μm). Agreement between predicted and actual vault was assessed using (1) intraclass correlation coefficient (ICC); (2) Bland-Altman analysis (95% limits of agreement, LoA); and (3) 95% confidence intervals for mean differences.</p><p><strong>Results: </strong>The mean age of the sample included in the prediction model was 28.18 ± 7.07 years. Vault was positively correlated with spherical equivalent (SE), white-to-white (WTW) horizontal corneal diameter, anterior chamber depth (ACD), anterior chamber volume (ACV), horizontal sulcus-to-sulcus (hSTS) diameter, pupil diameter, and maximum ciliary body thickness (CBTmax) and negatively correlated with age, intraocular pressure (IOP), crystalline lens rise (CLR), and trabecular-ciliary process angle (TCA). The vault prediction model (adjusted <i>R</i> ² = 0.54) was as follows: vault (μm) = -1711.7-166.8 × ICL size + 378.6 × WTW horizontal corneal diameter + 506.8 × ACD - 11.8 × TCA. In the validation cohort, the prediction model demonstrated clinical utility with 88.2% of outcomes within the ideal vault range (250-1000 μm) and 95.1% of errors within ±500 μm. The correlation coefficient between the predicted vault and the actual vault is 0.51 (<i>p</i> < 0.01). The bias between the predicted and actual vault is 203.20 μm, with a 95% LoA of (-175.30-581.70) μm and a standard deviation (SD) of 193.10 μm; the ICC between the predicted vault and the actual vault is 0.51 (95% CI: 0.40, 0.60).</p><p><strong>Conclusion: </strong>The vault prediction model, incorporating the posterior chamber structural parameter TCA, demonstrated favorable predictive performance in an independent validation cohort. It may serve as a useful supplementary tool for ICL size selection.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"5298174"},"PeriodicalIF":2.2,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13643204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149127877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A One-Year Visual and Safety Evaluation of a Newly Available Trifocal Intraocular Lens in Patients With Bilateral Cataracts: Clinical Outcomes From a Prospective Study.","authors":"Peter Mojžiš, Andrea Janeková, Lucia Hrčková, Iveta Němcová, Philipp Eberwein","doi":"10.1155/joph/5786325","DOIUrl":"10.1155/joph/5786325","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effectiveness and safety of a new trifocal intraocular lens (IOL) in patients with age-related cataracts 12 months after surgery.</p><p><strong>Methods: </strong>This prospective, noncomparative, multicenter study included 122 patients (244 eyes) undergoing cataract surgery with bilateral implantation of the AT ELANA 841P. At 12 months postoperatively, refraction and binocular visual acuity (VA) at distance (4 m), intermediate (80 cm), and near (40 cm) were measured. Visual symptoms and spectacle independence were subjectively evaluated. Safety assessment included the rate of ocular adverse events (AEs), posterior capsule opacification (PCO), IOL tilt and decentration, and glistening formation.</p><p><strong>Results: </strong>At 12 months postoperatively, most eyes (90.6%) were within ± 0.5 D spherical equivalent (SE) refraction, and almost all (99.6%) were within ± 1.0 D. Overall, 100% of patients achieved binocular uncorrected VA of 0.2 logMAR or better at distance. Performance at intermediate and near was 98.4% and 88.5%, respectively. All patients were spectacle-free at far and intermediate distances (100%), and 88.5% were spectacle-free for near tasks; over 80% reported no visual symptoms. The eye-related AE rate was low, with mild-to-moderate intensity. Up to 12 months, 91.7% of the eyes had no PCO, while 3.2% were treated with posterior capsulotomy. IOL tilt was not observed; only a small number of decentration cases were monitored, and these were clinically insignificant (< 1 mm) at the final visit. At 12 months, the IOL showed no glistening (97.5%) or traces only.</p><p><strong>Conclusion: </strong>Implantation of the AT ELANA 841P provided reliable refractive and visual outcomes, high rates of spectacle independence, and corrected and uncorrected VA at all distances. The IOL exhibited a favorable safety profile over 12 months, characterized by minimal visual symptoms, low PCO, no glistening (or only trace), and a stable position in the eye. <b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT06247683.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"5786325"},"PeriodicalIF":2.2,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13639549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149111147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultraviolet-C Light Emitter as a Method for Reducing Bacterial Contamination of Ophthalmic Instruments.","authors":"Raul Velez-Montoya, K Carolina Franco-Ramirez, Abril T Vargas-Fernández, Jesus E Arreola-Martinez, J Armando Cruz-Cervantes, Virginia Vanzzini-Zago, Jans Fromow-Guerra","doi":"10.1155/joph/6924280","DOIUrl":"10.1155/joph/6924280","url":null,"abstract":"<p><strong>Background: </strong>To assess the efficacy of an ultraviolet light type C (UVC) emitter in reducing bacterial load in common surgical equipment used during in-office ophthalmological procedures.</p><p><strong>Methods: </strong>We used 7 steam-sterilized lid speculums. The first one was the negative control. The second was left unprotected in a high-traffic area for 24 h before being cultivated. Lid speculums 3 to 7 were contaminated with a strain of <i>Staphylococcus epidermidis</i>, recovered from an active case of postoperative endophthalmitis. The third one was cultivated immediately after contamination. Lid speculums 4 to 7 were exposed to UVC for 30 s, 2, 5, and 10 min, respectively (continuous 254 nm UVC, irradiance > 160 mW/cm²). All speculums were cultivated on Mueller-Hinton agar plates for 48 h (≈21% O₂). Differences in bacterial load, observed colonies, and colony-forming units were assessed with a Kruskal-Wallis test. All experiments were done in triplicate.</p><p><strong>Results: </strong>We analyzed 27 bacterial cultures. After 24 h, lid speculum 2 showed growth of a single colony of <i>Sphingomonas paucimobilis.</i> After 30 s of UVC exposure, bacterial growth was 108 ± 7.2 CFU (bacterial load: 3240 ± 214.7). Bacterial growth decreased progressively with increasing UVC exposure, reaching no detectable growth after 5 min, representing a 100% reduction (<i>p</i> < 0.01). A second culture obtained from lid speculum 2 and the positive control after additional 5 min of UVC exposure also showed no bacterial growth.</p><p><strong>Conclusions: </strong>This exploratory laboratory study suggests that, after 5 min of UVC exposure using a commercially available emitter, no recoverable bacteria were detected on lid speculums under these experimental conditions. Although spores, fungi, and viruses were not evaluated, these findings suggest that UVC irradiation may be a feasible approach for reducing bacterial contamination of reusable instruments during in-office ophthalmic procedures.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"6924280"},"PeriodicalIF":2.2,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13617311/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changing Epidemiology of Refractive Disorders in the Western Pacific Region, 1990-2023: Evidence From the Global Burden of Disease Study 2023.","authors":"Yuqi Jiang, Shinan Wu, Yuling Chen, Jinzhi Peng, Zuguo Liu, Yalin Wu","doi":"10.1155/joph/1397428","DOIUrl":"10.1155/joph/1397428","url":null,"abstract":"<p><strong>Introduction: </strong>Refractive disorders (RDs) are a major cause of vision impairment worldwide. Although age-standardised rates have generally declined, the absolute burden, demographic drivers and future trends of RDs in the Western Pacific Region (WPR) remain incompletely characterised. This study assessed the long-term epidemiological patterns and projected burden of RDs in the WPR using data from the Global Burden of Disease Study 2023 (GBD 2023).</p><p><strong>Materials and methods: </strong>Data on prevalent cases, prevalence and disability-adjusted life years (DALYs) due to RDs from 1990 to 2023 were obtained from GBD 2023. Age-standardised prevalence rates (ASPRs) and age-standardised DALY rates (ASDRs) were evaluated globally and across 31 countries and territories in the WPR. Temporal trends were assessed using estimated annual percentage change and joinpoint regression. Age- and sex-specific patterns were examined, and Shapley decomposition was used to quantify the contributions of population growth, population ageing and epidemiological change. ARIMA models were used to project ASPR and ASDR to 2030.</p><p><strong>Results: </strong>In the WPR, prevalent cases increased from 23.45 million in 1990 to 39.75 million in 2023, while ASPR declined from 1606.27 to 1382.90 per 100,000 population. DALYs increased from 1.09 million to 1.75 million, whereas ASDR declined from 76.00 to 59.85 per 100,000. Age-specific burden increased markedly with age, and females generally experienced a higher burden than males, particularly in middle and older age groups. Joinpoint analyses identified long-term declines in ASPR and ASDR but modest rebounds after 2019. Population growth was the dominant positive contributor to increasing absolute burden in most WPR countries, while population ageing contributed substantially, particularly in East Asia and among females; epidemiological change generally offset part of these demographic increases. By 2030, ASPR and ASDR in the WPR were projected to decline further to 1317.70 (95% PI 1282.64-1352.76) and 55.00 (95% PI 52.66-57.34) per 100,000, respectively.</p><p><strong>Conclusion: </strong>Despite declining age-standardised rates, the absolute burden of RDs in the WPR continues to increase under demographic pressure. Continued population growth and ageing, together with persistent age and sex disparities, indicate that declining rates alone may underestimate future eye-care needs. Monitoring both age-standardised and absolute burden, alongside effective refractive error coverage, will be important for regional planning and progress towards the WHO 2030 targets.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"1397428"},"PeriodicalIF":2.2,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13602173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149039350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Lens Thickness and SRK/T Refractive Prediction Error After Cataract Surgery: A Single-Center Retrospective Cohort Study.","authors":"Tao Liu, Haifeng Jiang, Yanxia Tong, Zhanpeng Zhu, Lihan Luo, Yong Wang","doi":"10.1155/joph/4944226","DOIUrl":"10.1155/joph/4944226","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the association between lens thickness (LT) and SRK/T refractive prediction error following cataract surgery and to analyze its underlying mechanism.</p><p><strong>Methods: </strong>This retrospective cohort study collected data from patients who underwent surgical treatment for age-related cataracts between January 2025 and June 2025. Patients were stratified into three groups based on LT: Group 1 (< 4.0 mm), Group 2 (4.0 ≤ LT < 5.0 mm), and Group 3 (≥ 5.0 mm). Intraocular lens (IOL) power was calculated using the SRK/T formula. Manifest refraction results were collected at ≥ 4 weeks postoperatively. Accuracy of IOL power calculation was analyzed using prediction error (PE), mean absolute error (MAE), median absolute error (MedAE), and the proportions of PE within ±0.25 D, ±0.50 D, and ±1.00 D. Correlations between LT and effective lens position (ELP) as well as postoperative refractive error were assessed.</p><p><strong>Results: </strong>A total of 431 patients (431 eyes) were included, with a mean LT of 4.50 ± 0.58 mm. The overall mean PE was -0.08 ± 0.44 D, and the mean ELP_error was -0.04 ± 0.43 mm. Statistically significant differences were observed across the three LT groups for both PE (<i>F</i> = 25.742, <i>p</i> < 0.001) and ELP_error (<i>F</i> = 10.838, <i>p</i> < 0.001). ANCOVA was further performed to adjust for age, AL, ACD, and WTW. After adjustment, the LT group effect on PE remained significant (<i>F</i> = 14.960, <i>p</i> < 0.001, partial <i>η</i> ² = 0.066), with adjusted marginal means of -0.260 D, -0.118 D, and 0.165 D for Groups 1-3, respectively, and Bonferroni-corrected pairwise comparisons confirming significant differences across all three groups (all <i>p</i> < 0.05). Group 3 (LT ≥ 5.0 mm) exhibited a positive mean PE (0.16 ± 0.45 D), whereas Groups 1 and 2 showed negative PEs. The MAE was ranked from lowest to highest as follows: Group 2 (0.33 D) < Group 3 (0.37 D) < Group 1 (0.40 D). Group 2 (4.0 ≤ LT < 5.0 mm) achieved the lowest MedAE (0.29 D), the highest proportion of PE within ±0.50 D (78.3%), and 100.0% within ±1.00 D. Significant positive linear correlations were observed between LT and PE (<i>r</i> = 0.331, <i>p</i> < 0.001) and between LT and ELP_error (<i>r</i> = 0.226, <i>p</i> < 0.001). Multivariate linear regression identified LT as the strongest predictor of PE (<i>β</i> = 0.490, <i>p</i> < 0.001), followed by ACD (<i>β</i> = 0.217, <i>p</i> = 0.012) and WTW (<i>β</i> = 0.130, <i>p</i> = 0.031), with the model explaining 21.2% of the variance in PE.</p><p><strong>Conclusion: </strong>Increased deviation of LT from the mean results in larger ELP prediction errors and greater postoperative refractive error. Thin-lens eyes tended to be myopic, while thick-lens eyes tended to be hyperopic.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"4944226"},"PeriodicalIF":2.2,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13595810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149025088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}