{"title":"Nutrition and Metabolism Research Oral Paper Session Abstracts","authors":"","doi":"10.1002/jpen.2601","DOIUrl":"https://doi.org/10.1002/jpen.2601","url":null,"abstract":"","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139937353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introduction to Conference Abstracts","authors":"","doi":"10.1002/jpen.2598","DOIUrl":"10.1002/jpen.2598","url":null,"abstract":"","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139931583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Harry M. Vars Award Candidate Abstracts","authors":"","doi":"10.1002/jpen.2600","DOIUrl":"https://doi.org/10.1002/jpen.2600","url":null,"abstract":"","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139937354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Poster Abstracts","authors":"","doi":"10.1002/jpen.2604","DOIUrl":"10.1002/jpen.2604","url":null,"abstract":"","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merve Güner MD, Sinem Girgin MD, Tolga Yıldırım, Arzu Okyar Baş MD, Serdar Ceylan MD, Yelda Öztürk MD, Meltem Koca MD, Cafer Balcı, Burcu Balam Doğu, Mustafa Cankurtaran, Meltem Gülhan Halil
{"title":"Decreased abdominal wall muscle mass defined by muscle ultrasound is associated with malnutrition according to Global Leadership Initiative on Malnutrition criteria in renal transplant recipients: A cross-sectional study","authors":"Merve Güner MD, Sinem Girgin MD, Tolga Yıldırım, Arzu Okyar Baş MD, Serdar Ceylan MD, Yelda Öztürk MD, Meltem Koca MD, Cafer Balcı, Burcu Balam Doğu, Mustafa Cankurtaran, Meltem Gülhan Halil","doi":"10.1002/jpen.2608","DOIUrl":"10.1002/jpen.2608","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Changed body composition with increased fat content and decreased muscle mass is seen in renal transplantation recipients (RTRs). Increased fat mass might mask underlying muscle mass loss; measuring low body mass index and weight reduction alone may not be sensitive enough to diagnose malnutrition in RTRs. We aimed to determine the prevalence of malnutrition in stable RTRs using the Global Leadership Initiative on Malnutrition (GLIM) criteria and to assess the use of muscle ultrasonography (US) to compare the performance of various muscle US measurements in the diagnosis of reduced muscle mass.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ninety-one patients who had renal transplantation >6 months ago were enrolled in the study. GLIM criteria were performed for all patients, but not those at risk of malnutrition. Bioelectrical impedance analysis and muscle US were performed to identify reduced muscle mass.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The prevalence of malnutrition according to GLIM criteria was 25.3% (<i>n</i> = 23). All muscle US measurements were lower in the malnourished group than the well-nourished group; however, the malnourished group had substantially lower muscle thicknesses in abdominal muscles, specifically the external oblique (EO) and internal oblique (IO) muscles, than the well-nourished group (<i>P</i> = 0.001 and <i>P</i> = 0.007, respectively). There was a significant association between malnutrition and EO (odds ratio [OR] = 0.338, 95% CI = 0.163–0.699; <i>P</i> = 0.003) and IO (OR = 0.620, 95% CI = 0.427–0.900; <i>P</i> = 0.012) regardless of age and sex.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>One in four RTRs experience malnutrition. Muscle US could be used effectively for the diagnosis of reduced muscle mass and malnutrition in RTRs according to GLIM criteria.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Berkeley N. Limketkai MD, PhD, Sameeha Rau MD, Christina Fasulo MS, RD
{"title":"Preventative and therapeutic potential of nutrition for inflammatory bowel diseases: A narrative review","authors":"Berkeley N. Limketkai MD, PhD, Sameeha Rau MD, Christina Fasulo MS, RD","doi":"10.1002/jpen.2606","DOIUrl":"10.1002/jpen.2606","url":null,"abstract":"<p>Diet strongly shapes the gut microbiome and metabolome, which in turn influence intestinal inflammation in patients with inflammatory bowel disease (IBD). Separate from inflammation and malnutrition, diet's direct interactions with the gastrointestinal system can also provoke or attenuate a host of nonspecific gastrointestinal symptoms. Given these multifaceted effects of diet on inflammation and symptoms, nutrition has been investigated for its potential roles in the prevention and treatment of IBD. This review presents epidemiological, observational cohort, and clinical trial evidence that underlie our current understanding of nutrition for prevention and treatment of IBD.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139735476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between energy delivery from parenteral nutrition and refeeding syndrome in hospitalized adults: A retrospective cohort study","authors":"Nichakarn Apiromruck PharmD, BCP, Hasma Kano BSc, RD, Kittithat Taemkaew MD, Thammasin Ingviya MD, PhD, Utcharee Intusoma MD, PhD, Chaitong Churuangsuk MD, PhD","doi":"10.1002/jpen.2605","DOIUrl":"10.1002/jpen.2605","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Patients receiving parenteral nutrition (PN) may develop refeeding syndrome (RFS). This study determined RFS prevalence in hospitalized adults on PN and evaluated whether higher energy delivered by PN on day 1 of PN initiation was associated with RFS development.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We reviewed the medical records of adult patients receiving PN at a Thai quaternary hospital from June 2019 to May 2022. RFS was defined based on the Nutrition Management Clinical Practice Recommendation by the Society of Parenteral and Enteral Nutrition of Thailand. The association between PN energy delivery and RFS development was determined using a generalized estimating equation for multiple logistic regression analysis adjusted for NICE guideline risk factors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 547 patients was included (mean age 59.8 ± 17.2 years, mean body mass index 20.7 ± 4.8 ). The prevalence of RFS was 45%. Factors associated with RFS included energy from PN on the first day of PN initiation (adjusted odds ratio [aOR] 1.17; 95% CI 1.04–1.33; for every 5 kcal/kg/day increase), starvation >5 days prior to PN (aOR 1.54; 95% CI 1.04–2.26), concomitant diuretic use (aOR 1.81; 95% CI 1.25–2.64), low baseline potassium level (aOR 1.79; 95% CI 1.19–2.70), and individual compounding PN (aOR 1.61; 95% CI 1.04–2.51).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>RFS was common among hospitalized patients receiving PN. The amount of energy delivered on the first day of PN was independently associated with RFS, raising a concern regarding initiation of PN with higher energy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139717664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian Stoppe MD, Gunnar Elke MD, Simone Chaves de Miranda Silvstre MD, Matthew Kappus MD
{"title":"Highlights in the clinical nutrition literature: A critical appraisal of current research","authors":"Christian Stoppe MD, Gunnar Elke MD, Simone Chaves de Miranda Silvstre MD, Matthew Kappus MD","doi":"10.1002/jpen.2599","DOIUrl":"10.1002/jpen.2599","url":null,"abstract":"<p>Within the American Society for Parenteral and Enteral Nutrition (ASPEN), the Physician Engagement Committee (PEC) was created in 2017 by the ASPEN Board of Directors with the goal of growing the physician community both nationally and internationally. The PEC meets each month throughout the year to develop educational and research initiatives. In 2022, the PEC began an initiative to systematically review and evaluate practice-changing literature annually with the overall aim to highlight these studies at the annual ASPEN conferences and to critically discuss the potential clinical implications. The objective of the held meeting session was to present identified key papers in the fields of critical care medicine, gastroenterology and hepatology, and adult internal medicine that were published in 2022, which would complement the knowledge of the pathogenesis, diagnosis, and management of nutrition topics as well as to identify areas of future research. Overall, several large-scale randomized controlled studies were identified in each of these sections, with practice-changing major results. This manuscript summarizes the information that was presented and the discussions that followed.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2599","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139677903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mina Sarofim MD, FRACS, Nima Ahmadi MBBS, FRACS, David L. Morris MD, PHD, FRACS
{"title":"Shifting the paradigm of long-term total parenteral nutrition: Lessons from renal dialysis","authors":"Mina Sarofim MD, FRACS, Nima Ahmadi MBBS, FRACS, David L. Morris MD, PHD, FRACS","doi":"10.1002/jpen.2602","DOIUrl":"10.1002/jpen.2602","url":null,"abstract":"<p>Parenteral nutrition (PN) stands analogous to renal dialysis in its role as replacement therapy to artificially substitute a failed organ system. Both therapies are lifesaving and allow patients to manage chronic conditions that would otherwise be fatal: just as dialysis circumvents compromised renal function to filter waste and excess fluid, PN bypasses a nonfunctional or absent gastrointestinal tract by delivering essential nutrients, protein, and fluid directly into the bloodstream. Through the lens of history, there have been many remarkable achievements of modern medicine. Renal dialysis is the pinnacle of organ replacement, which has transitioned from an emergency lifesaving procedure to a routine, gold-standard treatment for renal failure. Similarly, PN stands in its infancy on the cusp of a similar paradigm shift as a routine organ replacement therapy, which will improve patient survival and quality of life if we can address ongoing challenges, such as refining nutrient compositions to align more closely with physiological needs, reducing infection rates, mitigating liver dysfunction, and improving cost-efficiency.</p><p>The journey of renal dialysis begins in 1913 with the pioneering groundwork of John Jacob Abel. His “vividiffusion” invention was the first to demonstrate the principle of dialysis; however, it was not until the 1940s when Willem Kolff developed the first practical dialysis machine, known as the rotating drum kidney. This device was understandably rudimentary by today's standards, consisting of cellophane tubing wrapped around a drum submerged in a bath of dialysate, but it established the principle of removing waste products from the blood in acute kidney injury. This was succeeded by Fredrik Kiil's plate dialyzer, which became the standard for hemodialysis in the 1960s. The subsequent development of the hollow-fibre dialyzer by Belding Scribner and colleagues was another quantum leap. Scribner also introduced the arteriovenous shunt, which for the first time allowed for repeated access to the vascular system, making long-term dialysis possible.<span><sup>1, 2</sup></span> The advent of biocompatible membrane technology, refinement of dialysate composition to more closely mimic human plasma, and the development of sophisticated machines that closely monitor and adjust the dialysis process in real-time further enhanced efficacy and patient safety. These advancements have made renal dialysis a gold standard of care in end-stage renal disease in the absence of transplantation. Rather than the prospect of death within weeks, dialysis offers millions of patients globally a 5-year survival rate of >50% and an improved quality of life.<span><sup>3, 4</sup></span></p><p>In the 1960s, the modern concept of intravenous feeding was formulated, roughly 50 years after the foundation of dialysis was laid. Stanley Dudrick and colleagues meticulously identified requirements and techniques to deliver a complete nutrition solution i","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2602","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139650986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}