Journal of Parenteral and Enteral Nutrition最新文献

{"title":"Response to \"Parenteral nutrition and bioelectrical impedance analysis estimated fat-free mass in adult patients with chronic intestinal failure: A descriptive cohort study\".","authors":"Julia W Korzilius, Manon Dumont, Harriët Jager-Wittenaar, Geert J A Wanten, Heidi E E Zweers-van Essen","doi":"10.1002/jpen.2762","DOIUrl":"https://doi.org/10.1002/jpen.2762","url":null,"abstract":"","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between GLIM diagnosed malnutrition and 18-month mortality in hospitalized adults with congestive heart failure: A prospective cohort study.","authors":"Ruoshu Duan, Suxiu Chen, Suxia Li, Jie Ding, Lei Wang, Yangli Li, Jingjing Ren, Sujing Jiang","doi":"10.1002/jpen.2760","DOIUrl":"https://doi.org/10.1002/jpen.2760","url":null,"abstract":"<p><strong>Background: </strong>The Global Leadership Initiative on Malnutrition (GLIM) criteria have been validated in various clinical settings since 2018, but prospective validation in patients with congestive heart failure (CHF) who are hospitalized remains limited. This study compares the prognostic performance of the GLIM criteria and Mini-Nutritional Assessment (MNA)-defined malnutrition for all-cause mortality in CHF patients and explores the strongest predictive indicator within the GLIM criteria.</p><p><strong>Methods: </strong>This single-center prospective cohort study included inpatients with CHF. Agreement between the GLIM criteria and MNA was assessed using Cohen κ coefficient. Survival data were analyzed using Kaplan-Meier curves and adjusted Cox regression analyses.</p><p><strong>Results: </strong>Among 498 CHF inpatients, 84 (16.9%) died during the 18-month follow-up. Malnutrition prevalence was 47.2% and 50.4% based on the GLIM criteria and MNA, respectively (κ = 0.68; P < 0.001). Malnutrition was independently associated with a higher risk of all-cause mortality (GLIM criteria: hazard ratio, 2.16 [95% confidence interval (CI), 1.13-4.13]; MNA: hazard ratio, 4.28 [95% CI, 1.98-9.22]). Low body mass index was the strongest predictor of all-cause mortality in multivariable analysis (hazard ratio, 5.14; 95% CI, 3.19-8.27).</p><p><strong>Conclusion: </strong>The GLIM criteria showed strong consistency with MNA and effectively predicted all-cause mortality in CHF patients within 18 months.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of protein and amino acids supplements on muscle strength and physical performance: A scoping review of randomized controlled trials.","authors":"Alaa H Al-Rawhani, Siti Nur'Asyura Adznam, Zalina Abu Zaid, Nor Baizura Md Yusop, Hakimah M Sallehuddin, Mohammed A Alshawsh","doi":"10.1002/jpen.2749","DOIUrl":"https://doi.org/10.1002/jpen.2749","url":null,"abstract":"<p><p>Protein and amino acid supplementation is an effective intervention that significantly enhances physical function and reduces frailty and sarcopenia in older adults. This scoping review aims to map and synthesize the available evidence on the effects of various types of protein and amino acid supplementation in this population. Following the PRISMA-ScR guidelines, we conducted a literature search to identify clinical trials examining the effects of protein and amino acid supplementation, with or without physical exercise, on muscle strength, physical performance, and body composition in healthy, frail, or sarcopenic older adults. Our analysis of 80 trials with a total of 5290 participants examines the evidence for the effectiveness of protein supplementation in enhancing muscle strength and body composition. Whey protein, creatine, milk protein, leucine, essential amino acids, and soy protein were the most used types of protein, and our findings indicate that whey protein, creatine, and milk protein yield the best results when used in conjunction with resistance training. Additionally, leucine and milk protein have shown the potential to enhance body composition even without concurrent resistance training. In conclusion, studies on the effectiveness of whey protein in improving muscle strength and body composition in older adults with resistance training are inconsistent. More research is required to explore the potential benefits of soy and leucine-enriched supplements. Protein supplementation's impact on physical performance remains inconclusive. Further studies are needed to determine the effects of protein types and supplementation on muscle-related parameters in older adults.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between enteral nutrition initiation within 48 h of intubation and 90-day mortality in patients with severe acute heart failure requiring mechanical circulatory support: A retrospective cohort study.","authors":"Takeshi Saijo, Koji Yasumoto, Kayoko Ryomoto, Chika Momoki, Daiki Habu","doi":"10.1002/jpen.2759","DOIUrl":"https://doi.org/10.1002/jpen.2759","url":null,"abstract":"<p><strong>Background: </strong>We explored the association between the initiation of enteral nutrition within 48 h of intubation and 90-day mortality in patients with severe acute heart failure requiring mechanical circulatory support.</p><p><strong>Methods: </strong>We retrospectively analyzed patients with acute heart failure who were admitted to the critical care unit and underwent endotracheal intubation and mechanical circulatory support. Multivariate Cox proportional hazard models were used to evaluate the association between early enteral nutrition and 90-day mortality. Multivariate logistic regression analyses were used to evaluate the association between early enteral nutrition and the incidence of infectious- and enteral nutrition-related complications. The following variables were used in the analysis: sequential organ failure assessment, lactate, length of mechanical circulatory support, early enteral nutrition, body mass index, chronic renal failure, serum albumin level, cardiopulmonary arrest, diabetes mellitus, intraaortic balloon pump, venoarterial extracorporeal membrane oxygenation, and IMPELLA. These variables were then examined in models with different combinations for outcomes.</p><p><strong>Results: </strong>The analysis included 80 and 35 patients in the early and delayed enteral nutrition groups, respectively. Multivariate analysis indicated that early enteral nutrition was an independent factor for reduced 90-day mortality (model 1: hazard ratio = 0.39 [95% confidence interval = 0.19-0.77]; model 2: hazard ratio = 0.38 [95% confidence interval = 0.19-0.76]; model 3: hazard ratio = 0.41 [95% confidence interval = 0.20-0.81]; and model 4: hazard ratio = 0.38 [95% confidence interval = 0.19-0.76]). Furthermore, early enteral nutrition was an independent factor for infectious complications but not for enteral nutrition-related complications.</p><p><strong>Conclusion: </strong>Early enteral nutrition can be initiated without increasing complications in patients with severe acute heart failure requiring mechanical circulatory support. This may have beneficial effect on improving prognosis.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transition readiness assessment in adolescents and young adults with chronic intestinal failure on home parenteral nutrition: A descriptive cross-sectional study.","authors":"Aysenur Demirok, Marc A Benninga, Antonella Diamanti, Myriam El Khatib, Anat Guz-Mark, Johannes Hilberath, Cécile Lambe, Lorenzo Norsa, Anna Simona Sasdelli, Alida A Sanchez, Mireille Serlie, Merit M Tabbers","doi":"10.1002/jpen.2747","DOIUrl":"https://doi.org/10.1002/jpen.2747","url":null,"abstract":"<p><strong>Background and aims: </strong>Life expectancy for patients with chronic intestinal failure (CIF) recieving home parenteral nutrition (HPN) has improved over the past decades. Consequently, more children on HPN grow into adulthood. Until now, no assessment of transition readiness of these patients exists. Aim is to assess readiness of adolescents recieving HPN.</p><p><strong>Methods: </strong>This is an international, prospective, cross-sectional multicenter study in collaboration with members of the Intestinal Failure working group-European Reference Network for Rare Inherited and Congenital (Digestive and Gastrointestinal) Anomalies and the Network of Intestinal Failure and Intestinal Transplant in Europe-European Society for Pediatric Gastroenterology Hepatology and Nutrition conducted between April and November 2023. A validated Transition Readiness Assessment Questionnaire was used to measure patient- and parent-reported transition readiness in adolescents on HPN.</p><p><strong>Results: </strong>A total of 57 participants aged 16 to 24 years were included across eight countries. Patient-reported outcomes show a lack of readiness for transition among the total cohort with 65% scoring below the threshold. Younger patients (aged 16-18 years), male patients, and those in pediatric settings reported significant lower readiness. Parent-reported scores were higher compared with the patient-reported outcomes, reaching the threshold for transition readiness.</p><p><strong>Conclusion: </strong>The transition readiness of adolescents with CIF receiving HPN presents is proven to be low. This study underscores the necessity for the use of a standardized transition protocol. Emphasizing the importance of successful transition in this vulnerable patient group will enhance the outcomes and independence of adolescents during their transition into the adult healthcare system.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143803467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of dietitians in optimizing medical nutrition therapy in cardiac surgery patients: A secondary analysis of an international multicenter observational study","authors":"Ellen Dresen PhD,&nbsp;Danielle E. Bear PhD,&nbsp;Ashley DePriest RD,&nbsp;Ranna Modir MS, RD,&nbsp;Omy Naidoo RD,&nbsp;Charlene Compher RD, PhD,&nbsp;Andrea Ho RD,&nbsp;Pui Hing Foong MSc,&nbsp;Maria Eloisa Garcia Velásquez MD,&nbsp;Zheng-Yii Lee PhD,&nbsp;Charles Chin Han Lew APD, PhD,&nbsp;Gunnar Elke MD,&nbsp;Jayshil J. Patel MD,&nbsp;Liam McKeever RDN, PhD,&nbsp;Katharina Berschauer MD,&nbsp;Catarina Rosa Domingues RD, BSc,&nbsp;Juan Carlos Lopez-Delgado MD, PhD,&nbsp;Patrick Meybohm MD,&nbsp;Daren K. Heyland MD, MSc,&nbsp;Christian Stoppe MD","doi":"10.1002/jpen.2755","DOIUrl":"10.1002/jpen.2755","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Better understanding the impact of dietetic services on nutrition practices seems required as it may represent an opportunity for optimization in post–cardiac surgery patients. The present study aims to evaluate and compare nutrition practices and clinical outcomes in post–cardiac surgery intensive care unit (ICU) patients with and without dietetic services.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is a secondary analysis of a multinational prospective observational study in patients (<i>n</i> = 237) with &gt;72 h of post–cardiac surgical ICU stay with and without dietetic services describing nutrition practices and outcomes up to 12 days after ICU admission.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Dietetic services were available in 61.5% (8 of 13) ICUs (1.0 ± 0.5 full-time equivalents/10 beds). Enteral nutrition was initiated &lt;48 h from ICU admission in 49.6% and 59.1% of patients at sites with vs without dietetic services, respectively. Parenteral nutrition was started within 118.3 ± 56.5 and 131.5 ± 69.2 h at sites with vs without dietetic services, respectively. Energy target (23.7 ± 4.8 vs 24.6 ± 4.8 kcal/kg body weight/day) and actual supply (10.5 ± 6.7 vs 10.3 ± 6.2 kcal/kg body weight/day) did not differ between the groups. Protein targets (1.4 ± 0.4 vs 1.1 ± 1.3 g/kg body weight/day) and actual protein provision (0.6 ± 0.4 vs 0.4 ± 0.3 g/kg body weight/day) were higher in patients at sites with vs without dietetic services.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Improvements in medical nutrition therapy practices in patients after cardiac surgery are needed in ICUs with and without dietetic services. Appropriately staffed dietetic services as essential members of the medical care team may be crucial to transfer knowledge on adequate medical nutrition therapy strategies into practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 4","pages":"476-487"},"PeriodicalIF":3.2,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2755","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143795686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing pregnancy with long-term parenteral nutrition: A case report and review of the literature","authors":"Muhammad Shahzil MD,&nbsp;Ammad Javaid Chaudhary MD,&nbsp;Abdullah Sohail MD,&nbsp;Kamran Haq MD,&nbsp;Muhammad Zarrar Khan MD,&nbsp;Yakir Muszkat MD,&nbsp;Syed-Mohammed Jafri MD","doi":"10.1002/jpen.2758","DOIUrl":"10.1002/jpen.2758","url":null,"abstract":"<p>Parenteral nutrition (PN) is essential for patients with chronic intestinal failure but poses significant challenges during pregnancy because of increased nutrition needs and associated risks such as central line–associated bloodstream infections. We report a case of a 29-year-old primigravid woman with Crohn's disease who required chronic PN. Despite these complexities, her pregnancy was managed successfully with tailored PN adjustments. She developed intrahepatic cholestasis of pregnancy at 38 weeks and delivered a healthy, full-term newborn. Meticulous planning and individualized nutrition management are crucial in navigating the complexities of PN during pregnancy, demonstrating the potential for successful outcomes with strategic and personalized interventions.</p>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 4","pages":"528-533"},"PeriodicalIF":3.2,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2758","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"JPEN Journal Club 92. Adjusting randomized trials.","authors":"Ronald L Koretz","doi":"10.1002/jpen.2750","DOIUrl":"https://doi.org/10.1002/jpen.2750","url":null,"abstract":"","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recognizing malnutrition in adults with critical illness: Guidance statements from the Global Leadership Initiative on Malnutrition","authors":"C. W. Compher PhD, RD,&nbsp;R. Fukushima MD, PhD,&nbsp;M. I. T. D. Correia MD, PhD,&nbsp;M. C. Gonzalez MD, PhD,&nbsp;L. McKeever PhD, RD,&nbsp;K. Nakamura MD, PhD,&nbsp;Z. Y. Lee PhD, RD,&nbsp;J. J. Patel MD,&nbsp;P. Singer MD,&nbsp;C. Stoppe MD, PhD,&nbsp;J. C. Ayala MD, PhD,&nbsp;R. Barazzoni MD, PhD,&nbsp;M. M. Berger MD, PhD,&nbsp;T. Cederholm MD, PhD,&nbsp;K. Chittawatanarat MD, PhD,&nbsp;A. Cotoia MD, PhD,&nbsp;J. C. Lopez-Delgado MD, PhD,&nbsp;C. P. Earthman PhD, RD,&nbsp;G. Elke MD, PhD,&nbsp;W. Hartl MD,&nbsp;M. S. Hasan MD, PhD,&nbsp;N. Higashibeppu MD, PhD,&nbsp;G. L. Jensen MD, PhD,&nbsp;K. J. Lambell PhD, RD,&nbsp;C. C. H. Lew PhD, RD,&nbsp;J. I. Mechanick MD,&nbsp;M. Mourtzakis PhD,&nbsp;G. C. C. Nogales MD,&nbsp;T. Oshima MD, PhD,&nbsp;S. J. Peterson PhD, RD,&nbsp;T. W. Rice MD,&nbsp;R. Rosenfeld MD, PhD,&nbsp;P. Sheean PhD, RD,&nbsp;F. M. Silva PhD, RD,&nbsp;P. C. Tah PhD, RD,&nbsp;M. Uyar MD","doi":"10.1002/jpen.2748","DOIUrl":"10.1002/jpen.2748","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Patients with critical illness may present with disease-related malnutrition upon intensive care unit (ICU) admission. They are at risk of development and progression of malnutrition over the disease trajectory because of inflammation, dysregulated metabolism, and challenges with feeding.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The Global Leadership Initiative on Malnutrition (GLIM) convened a panel of 36 clinical nutrition experts to develop consensus-based guidance statements addressing the diagnosis of malnutrition during critical illness using a modified Delphi approach with a requirement of ≥75% agreement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>(1) To identify pre-existing malnutrition, we suggest evaluation within 48 h of ICU admission when feasible (100% agreement) or within 4 days (94% agreement). (2) To identify the development and progression of malnutrition, we suggest re-evaluation of all patients every 7–10 days (97% agreement). (3) To identify progressive loss of muscle mass, we suggest evaluation of muscle mass as soon as feasible (92% agreement) and again after 7–10 days (89% agreement). (4) To identify the development and progression of malnutrition before and after ICU discharge, we suggest re-evaluating nutrition status before ICU discharge and during clinical visits that follow (100% agreement).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Research using consistent etiologic and phenotypic variables offers great potential to assess the efficacy of nutrition interventions for critically ill patients with malnutrition. Assessment of these variables during and beyond the ICU stay will clarify the trajectory of malnutrition and enable exploration of impactful treatment modalities at each juncture. GLIM offers a diagnostic approach that can be used to identify malnutrition in critically ill patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 4","pages":"405-413"},"PeriodicalIF":3.2,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jpen.2748","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143753222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between a 6-h feeding protocol and postprocedure hospital length of stay following percutaneous endoscopic gastrostomy in hospitalized adults: A before-and-after cohort study","authors":"Jeffrey L. Roberson MD, MBA","doi":"10.1002/jpen.2754","DOIUrl":"10.1002/jpen.2754","url":null,"abstract":"","PeriodicalId":16668,"journal":{"name":"Journal of Parenteral and Enteral Nutrition","volume":"49 4","pages":"404"},"PeriodicalIF":3.2,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143710351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}