Journal of Parasitic Diseases最新文献

{"title":"Correction to: Prevalence and risk factors associated with intestinal acaroid mite and helminthic infection among school-aged children in Northern Egypt.","authors":"Sarah M Abdo, Mohamed Mostafa Tahoun, E S El-Wakil, Yusuf A Edmardash, Hend A El-Taweel, Heba Elhadad, Hend Hamdy, Ramy Mohamed Ghazy","doi":"10.1007/s12639-025-01857-5","DOIUrl":"https://doi.org/10.1007/s12639-025-01857-5","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1007/s12639-025-01835-x.].</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"513"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222132/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural compound malabaricone conjugated with silver nanoparticle as an antiamoebic agent against primary Amoebic Meningoencephalitis (PAM) caused by <i>Naegleria fowleri</i>.","authors":"Kavitha Rajendran, Devandran Apparasamy, Niwasini Krishna Kumar, Usman Ahmed, Haema Thevanayagam, Muhamad Aqmal Othman, Ayaz Anwar","doi":"10.1007/s12639-025-01886-0","DOIUrl":"10.1007/s12639-025-01886-0","url":null,"abstract":"<p><p><i>Naegleria fowleri</i>, a free-living waterborne amoeba, causes fatal primary amoebic meningoencephalitis (PAM) when it enters the brain through the nose. Treatment options are limited due to a lack of FDA-approved drugs and poor blood-brain barrier penetration. Silver nanoparticles exhibit potent antiamoebic properties and can enhance the efficacy of therapeutic agents at specific biological targets. Natural folk remedies have long been utilised in disease treatment, with phytochemicals from various plants demonstrating significant amoebicidal properties. These bioactive compounds offer potential therapeutic benefits against amoebic infections. In this study, malabaricones A, B, and C, extracted from Myristica cinnamomea, were conjugated with silver nanoparticles (AgNO₃) to determine their effects on PAM infection. These AgNPs coated with malabaricones (AgNPs-Mal-A, B, C) were characterised by using UV-visible spectrophotometry and gave a maximum absorbance at 422, 436, and 457 nm, while high-resolution transmission electron microscopy showed the nanoconjugates were regular and rounded in shape, respectively. These nanoconjugates were evaluated against trophozoites of <i>N. fowleri</i>. All three nanoconjugates showed potent activity; however, based on IC₅₀ values, Mal A-AgNPs demonstrated the highest potency, followed by Mal B-AgNPs and Mal C-AgNPs. While Mal C-AgNPs exhibited stronger effects at higher concentrations, its overall potency appears lower compared to Mal A-AgNPs. The morphological changes were recorded via scanning electron microscopy, while viability was illustrated via light microscopy. All nanoconjugates significantly reduced the host cell cytopathogenicity but showed moderate toxicity at lower concentrations against HaCaT cells. The results indicate that all three tested nanoconjugates show potential as effective alternative therapeutic agents against <i>N. fowleri</i> infections.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"493-507"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and larval morphology of <i>Nematodirus spp.</i> in sheep raised under traditional husbandry system In district Kargil, a Trans-Himalaya region of India.","authors":"Shabbir Hussain, Aqleemul Islam, Zeenat Islam, Fayaz Ahmad, Kamal Jaiswal, Suman Mishra","doi":"10.1007/s12639-025-01865-5","DOIUrl":"https://doi.org/10.1007/s12639-025-01865-5","url":null,"abstract":"<p><p>Even though the extreme cold is detrimental to the development and survival of gastrointestinal nematodes, <i>Nematodirus</i> is an important genus in terms of disease and production loss, as it requires a chilling temperature for its development. This is the first cross-sectional study that was carried out to investigate the larval morphology, prevalence, and intensity of infection, and the associated risk factors of <i>Nematodirus spp.</i> in sheep kept under the traditional husbandry system in the district Kargil, a Trans-Himalayan region of India, from March 2021 to February 2023. A total of 814 faecal samples (Year 1- 404; Year 2- 410) were examined. The morphology and micrometry study of eggs was conducted for the prevalence, while the parasite burden was determined using the modified McMaster technique. A larval morphology and micrometry study was conducted to identify species.Larval culture reports revealed that the differential larval count of <i>Nematodirus spp.</i> were 2.89% in year 1 and 2.6% in year 2 with a range of (0-8%) and (0-10%) respectively. The mean level of infection was recorded below 80 eggs per gram [EPG]. An overall 42.5% in year 1 and 40% in year 2 were found to be infected with <i>Nematodirus spp</i>. Season, sex, age, and breed were found to be relevant major risk factors that influenced the prevalence of parasites. The prevalence of <i>Nematodirus spp.</i> was significantly (<i>p</i> < 0.05) associated with seasons, age groups, and different breeds but not with gender (sex) (<i>p</i> > 0.05). Thus, it may be concluded that the purpose of the current study is not only to assess the widespreadness of infection but also to monitor and forecast future outbreaks of this important genus.</p><p><strong>Graphical abstract: </strong>The morphology study based on egg, larvae revealed that the Nematodirus spp. inhabited in the sheep raised in Kargil Ladakh, India. Larval culture findings revealed the two species of Nematodirus, Nematodirus spathiger and Nematodirus filicollis. Overall: Nematodirus spp. was found 42.5% in year 1 and 40% in year 2.The mean level of infection was recorded below 80 eggs per gram (EPG). Maximum incidence of infection found in spring and minimum in summer.Season, sex, age and breed are the various risk factors that influence the prevalence of Nematodirus spp. in sheep of Kargil Ladakh.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"372-383"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222133/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: Sparganosis in <i>Minervarya pierrei</i> (Dubois, 1975) (Amphibia: Anura: Dicroglossidae), a new host from India.","authors":"Neelanjana Saha, Sudheer Kumar Jena, Oindrila Paul, Suman Das, Upasana Bhattacharya, Anjum N Rizvi, Pratyush P Mohapatra","doi":"10.1007/s12639-025-01845-9","DOIUrl":"https://doi.org/10.1007/s12639-025-01845-9","url":null,"abstract":"<p><p>The present study reports sparganosis in <i>Minervarya pierrei</i> (Dubois, 1975) from Jharkhand, India. While human cases of sparganosis have been documented in India, this study provides a confirmed record of this parasite in an amphibian host from the country. The parasites collected from the thigh muscles of the hosts were morphologically identified as belonging to the genus <i>Spirometra</i>. This finding expands the known host range of <i>Spirometra</i> in India and highlights the need for systematic screening of such infections in the natural environment and museum collections to assess the prevalence and transmission dynamics of sparganosis in Indian amphibian populations.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12639-025-01845-9.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"509-512"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sero-positivity of anti-<i>Toxoplasma gondii</i> and anti-<i>Neospora caninum</i> antibodies among cattle and buffaloes from delta of Egypt.","authors":"Hany M Ibrahim, Adel A-H Abdel-Rahman, Nora M Bishr, Ahmed Ghonim, Dalia S Morsi","doi":"10.1007/s12639-025-01858-4","DOIUrl":"https://doi.org/10.1007/s12639-025-01858-4","url":null,"abstract":"<p><p>Due to the scarcity of data on the sero-positivity of anti-<i>T. gondii</i> & anti-<i>N. caninum</i> antibodies and the worldwide importance of these protozoans in the Republic of Egypt, our research aimed to discover the sero-prevalence of <i>T. gondii</i> & <i>N. caninum</i> in buffaloes & cows from some Delta of Egypt provinces. Both IgG & IgM against these protozoans were detected using specific recombinant surface Ag 2 of <i>T. gondii</i> (<i>Tg</i>SAG2) & surface Ag 1 of <i>N. caninum</i> (<i>Nc</i>SAG1) based ELISA. The overall sero-positivity of anti-<i>N. caninum</i> in cows from Gharbia, Beheira and Menoufia provinces were (22.19% for IgM) and (38.13% for IgG), respectively. While sero-positivity of anti-<i>T. gondii</i> in cows from the same examined provinces were (16.88% for IgM) and (31.88% for IgG), respectively. In buffaloes, the overall sero-positivity of anti- <i>Neosporoa caninum</i> from Gharbia, Damietta and Menoufia provinces were (6.82% for IgM) and (15.45% for IgG), respectively. While the total sero-positivity of anti-<i>T. gondii</i> in buffaloes from the Gharbia, Damietta and Menoufia provinces were (7.27%for IgM) and (16.82% for IgG), respectively. The rates of mixed infections were 16.56% in cattle & 9.09% in buffaloes. This study showed significant differences regarding the age; gender & season in cattle while in buffaloes significant changes were demonstrated regarding the age & season. In conclusion, toxoplasmosis and neosporosis are prevalent in cattle and buffaloes in the studied Provinces of the Delta of Egypt. In turn, these infections will represent a possible contaminated source for human infection and could affect the livestock industry development in Egypt.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12639-025-01858-4.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"341-347"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular epidemiology and risk factors associated with <i>Babesia spp</i> infections in cattle in Imbo region, Burundi.","authors":"Eric Ndayikengurukiye, Jean Bosco Ntirandekura, Lionel Nyabongo, Amos Amore, Francis McOdimba","doi":"10.1007/s12639-025-01871-7","DOIUrl":"10.1007/s12639-025-01871-7","url":null,"abstract":"<p><p>Bovine Babesiosis is one of the tick-borne diseases (TBD) caused by <i>Babesia spp</i> and is transmitted by tick vectors of the genus <i>Rhipicephalus microplus</i>. The disease causes significant economic loses to livestock farmers and it has been reported to be endemic in many countries of East African region including Burundi. A recent study conducted in Burundi showed that the vectors of the disease are present in different agro-ecological zones. A cross-sectional study was conducted in the Imbo region to assess the prevalence and risk factors associated with bovine babesiosis. A total of 400 blood samples drawn from cattle were collected from either jugular or coccinea vein. Nested Polymerase Chain Reaction (nPCR) assay based on rhoptry associated protein-1a (<i>Rap-1a)</i>, and spherical body protein-4 (<i>SBP-4)</i> was used for pathogen detection and the resulting data was used to determine the risk factors using the R statistical software. Gene sequences and the genetic characterization were determined for selected positive samples. Out of a total of 400 samples, 5.50% (3.3-7.8, 95% CI) were found to be infected with <i>Babesia spp</i> where 4.25% (2.3-6.2, 95% CI) and 1.25% (0.2-2.3, 95% CI) were infected with <i>B. bigemina</i> and <i>B. bovis</i> respectively. Age, sex, tick infestation, grazing system, and origin (commune) were found to be significantly associated with bovine babesiosis (<i>P</i> value < 0.05). The sequence analysis revealed that different genotypes of <i>B. bigemina</i> and <i>B. bovis</i> are present in the Imbo region and these results will help the competent authorities to design an effective strategy for the control of tick-borne diseases to reduce the economic losses causes by the diseases.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"399-410"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222155/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First report on coinfection of <i>Fasciola jacksoni</i> and <i>Pseudodiscus collinsi</i> in a free-ranging wild Asian elephant (<i>Elephas maximus</i>) in the Nilgiris, Tamil Nadu, India.","authors":"M Aravind, K Jeeva, S T Bino Sundar, K Rajesh Kumar, P N Richard Jagatheesan","doi":"10.1007/s12639-025-01878-0","DOIUrl":"https://doi.org/10.1007/s12639-025-01878-0","url":null,"abstract":"<p><p>In the present study 32 wild elephants across different forest ranges of the Nilgiris were screened for the presence of flukes during necropsy from December 2023 to November 2024, out of which only one elephant was found to be infected with flukes. The occurrence of <i>Fasciola jacksoni</i> flukes in liver and <i>Pseudodiscus collinsi</i> flukes in the caecum and colon of a Thirty five year old, free ranging male elephant (<i>Elephas maximus</i>) is reported. The infected elephant harboured a total of 22 numbers of <i>F</i>. <i>jacksoni</i> in the liver and 487 numbers of <i>P</i>. <i>collinsi</i> flukes in the caecum and colon. Morphologically <i>F</i>. <i>jacksoni</i> flukes were flat with ill-defined cephalic end armed with numerous minute dermal spines at both dorsal and ventral surfaces. Oral sucker was terminal and small whereas ventral sucker was large and well forward. Intestinal caeca were branched occupying nearly the whole extent of the body internally. Body of <i>P</i>. <i>collinsi</i> flukes were tapering anteriorly and rounded posteriorly with oral pouches and wavy intestinal caeca. The testes were deeply lobed, placed side by side and ovary was single, posterior to testes. The ventral sucker was subterminal. Liver of the elephant infected with <i>F. jacksoni</i> was enlarged, congested, hemorrhagic and bile tracts were filled with a dark yellowish deposition with numerous immature and mature flukes present inside the liver. Though numerous <i>P</i>. <i>collinsi</i> flukes were found in the caecum and colon, no pathological lesions were appreciable. The present observations on coinfection of <i>Fasciola jacksoni</i> and <i>Pseudodiscus collinsi</i> in a free ranging wild elephant seems to be the first report of its kind and will be important to map the status of fluke infections in wild elephants and to frame control strategies.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"444-451"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro, in vivo, and anticytotoxic effects of silver nanoparticles green synthesized by <i>Astragalus baba-alliar</i> against <i>Giardia lamblia</i> infection.","authors":"Massumeh Saadatmand, Amal Khudair Khalaf, Fatemeh Azadbakht, Hasip Cem Özyurt, Sara Golabi Azad","doi":"10.1007/s12639-025-01868-2","DOIUrl":"https://doi.org/10.1007/s12639-025-01868-2","url":null,"abstract":"<p><p>Now, numerous synthetic medications are available for managing giardiasis, such as metronidazole, furazolidone, and tinidazole. These pharmaceuticals are associated with various adverse effects. The present experimental investigation aims to assess the in vitro <i>and</i> in vivo effects of silver nanoparticles (SNP) synthesized <i>Astragalus baba-alliar</i> extract against <i>Giardia lamblia</i>. The precipitation technique was utilized for the eco-friendly synthesis of SNP by reducing silver ions. An in vitro study was conducted on <i>G. lamblia</i> cysts and trophozoites following exposure to varying concentrations of SNP (10-200 µg/mL) for durations ranging from 10 to 360 min. The impact of SNP on trophozoite plasma membrane integrity and its cytotoxic effects on both normal and colon cancer cells were evaluated. In the subsequent in vivo experiment, BALB/c mice infected with <i>Giardia</i> were administered SNP at doses of 10, 15, and 20 mg/kg/day for a duration of one week. Stool examinations were conducted on the 8th day post-infection to assess the presence of Giardia cysts and determine the reduction rate. The study found that the size of synthesized SNP ranged from 10 to 90 nm, with the highest concentration of particles falling within the 35-45 nm range. The administration of SNP significantly elevated the mortality rate of <i>G. lamblia</i> cysts in a dose-dependent manner. Specifically, at concentrations of 100 and 200 μg/mL, SNP effectively eradicated <i>G. lamblia</i> cysts after 120 and 240 h, respectively. In an in vivo setting, the treatment of infected mice with SNP at doses of 10, 15, and 20 mg/kg likewise led to a dose-dependent reduction in the viability of <i>G. lamblia</i> cysts. Exposing <i>G. lamblia</i> trophozoites to SNP led to a dose-dependent elevation in the permeability of trophozoite plasma membranes. The 50% cytotoxic concentrations (CC50) values of SNP for colon cancer and normal cell lines were measured at 361.7 μg/mL and 769.9 μg/mL, respectively. The calculated selectivity index value, which exceeds 2 (2.13), suggests that the SNP demonstrates a higher safety profile for normal cells compared to cancer cells. The experimental investigation demonstrated that SNP produced using <i>A. baba-alliar</i> exhibited significant anti-<i>Giardia</i> activity both in laboratory settings (in vitro) and in living organisms (in vivo), suggesting its potential as a treatment for <i>Giardia</i> infections. However, further studies are needed to elucidate the precise mechanisms of action and thoroughly evaluate the toxicity profile of this type of SNP.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"452-460"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of intestinal parasitic infections on haemato-immunological profile of prison inmates in Southern Ghana.","authors":"Albert Abaka-Yawson, Daniel Sai Squire, Godsway Edem Kpene, Joseph Boachie, Serwaa Akoto Bawua, John Arko-Mensah","doi":"10.1007/s12639-025-01852-w","DOIUrl":"https://doi.org/10.1007/s12639-025-01852-w","url":null,"abstract":"<p><p>Intestinal parasites are known to cause changes in blood count parameters and immunological markers among various populations. Prison inmates often have poor living conditions and limited access to healthcare, thus infections with intestinal parasites could negatively impact on their overall health and wellbeing. This study assessed the effects of intestinal parasitic infections on the haemato-immunological profile of prison inmates in Southern Ghana. A cross-sectional study using stratified sampling technique was conducted among 347 male prison inmates in three major prisons in Southern Ghana, with 44 from Ho Central prison, 257 from Nsawam Medium Security prison and 46 from Sekondi Central prison. Stool samples obtained from inmates were first concentrated using formol-ether, then stained with the modified Ziehl-Neelsen technique to determine the presence of intestinal parasites. Additionally, venous blood was drawn into EDTA tubes from each participant and analysed for full blood count parameters using an automated haematology analyser, SYSMEX XN-550. Interleukin-10 (IL-10) and Immunoglobulin E (IgE) levels were determined by ELISA. The predominant intestinal parasites identified in the study were <i>Ascaris lumbricoides</i> and <i>Entamoeba histolytica</i> which accounted for 46.6% and 18.5% of all infections identified. Compared to uninfected individuals, there was a positive relationship between intestinal parasitic infection and total white blood cell count (5.38 (3.60) vs. 4.40 (2.41) 10⁹/L; <i>p</i> = 0.022), eosinophils (0.30(0.51) vs. 0.25(0.34) 10⁹/L; <i>p</i> = 0.028) and basophil (0.05(0.04) vs. 0.04(0.02) 10⁹/L; <i>p</i> = 0.044) respectively. In addition, IgE (<i>p</i> < 0.001) and IL-10 (<i>p</i> = 0.008) levels were significantly higher among infected inmates. After adjusting for confounders, total white blood cell count (<i>p</i> = 0.003) and eosinophil count (<i>p</i> = 0.032) were associated with intestinal parasitic infection status. Intestinal parasitic infection was associated with leukocytosis and eosinophilia as well as elevated IgE and IL-10 levels among prison inmates. Future trials should evaluate the impact of regular deworming and nutritional supplementation on haematological and immunological outcomes.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"299-308"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222135/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual primary hydatid cysts of the body without liver and lung involvement.","authors":"Yener Aydin, Ali Bilal Ulas, Suat Eren, Gurkan Ozturk, Kamber Kasali, Yilmaz Aksoy, Mehmet Kursat Karadag, Eyup Senocak, Abdurrahim Colak","doi":"10.1007/s12639-025-01860-w","DOIUrl":"https://doi.org/10.1007/s12639-025-01860-w","url":null,"abstract":"<p><p>The aim of this study was to investigate hydatid cysts observed in unusual localizations of the body without liver and lung involvement. A single-center retrospective study was conducted between 2000 and 2024, evaluating a total of 173 cases of hydatid cysts located in uncommon regions of the body, excluding liver and lung involvement. Unusual hydatid cysts accounted for 4.8% (173/3623) of all hydatid cysts. Among the cases, 89 (51.4%) were female and 84 (48.6%) were male. The cohort included 49 children (≤ 18 years, 28.3%) and 124 adults (> 18 years, 71.7%), with a mean age of 33.7 ± 20.2 years (range: 5-85 years). The distribution of hydatid cysts included the spleen in 34 cases (19.7%), kidney in 27 (15.6%), intracranial in 24 (13.9%), muscle in 23 (13.3%), bone in 15 (8.7%), mediastinum in 10 (5.8%), pelvic space in 9 (5.2%), cardiac in 8 (4.6%), subcutaneous and soft tissue in 6 (3.5%), omentum in 6 (3.5%), ovarian fossa in 3 (1.7%), diaphragm in 3 (1.7%), pancreas in 3 (1.7%), uterine wall in 1 (0.6%), retroperitoneal space in 1 (0.6%), nasal cavity in 1 (0.6%), and thyroid in 1 (0.6%). Primary surgical treatment was applied to 144 cases (83.2%). Primary hydatid cysts are less common in other parts of the body without involvement of the liver and lungs. Surgical resection remains the preferred treatment method for these cases, where diagnosis can be challenging.</p>","PeriodicalId":16664,"journal":{"name":"Journal of Parasitic Diseases","volume":"50 2","pages":"332-340"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13222134/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148143663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}